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Journal Articles

Mechanisms of Deregulation of Apoptosis in Myeloma

Simone Fulda, MD

Blood (2019) 134 (Supplement_1): SCI-10.

https://doi.org/10.1182/blood-2019-121102

Published: 2019

Journal Articles

Biomarker of sensitivity to PR-104 in leukemia

Simone Fulda

Blood (2015) 126 (10): 1153–1154.

https://doi.org/10.1182/blood-2015-07-655225

Published: 2015

Journal Articles

Smac mimetic and glucocorticoids synergize to induce apoptosis in childhood ALL by promoting ripoptosome assembly

Katharina Belz, Hannah Schoeneberger, Sibylle Wehner, Andreas Weigert, Halvard Bönig, Thomas Klingebiel, Iduna Fichtner, Simone Fulda

Blood (2014) 124 (2): 240–250.

https://doi.org/10.1182/blood-2013-05-500918

Published: 2014

Includes: Supplemental data

Journal Articles

Activation of Acute Lymphocytic Leukemia Blasts with CpG ODN, IL-4 and CD40 Ligand Facilitates Enhanced Anti-Leukemic CTL Responses

Dorit Fabricius, Lucia Breckerbohm, Manon Queudeville, MD, Angelika Vollmer, Sarah M. Eckhoff, MD, Johanna Pfeil, Gudrun Strauss, PhD, Simone Fulda, MD, Bernd Jahrsdoerfer, MD, Lueder H Meyer, MD, Klaus-Michael Debatin, MD

Blood (2010) 116 (21): 3907.

https://doi.org/10.1182/blood.V116.21.3907.3907

Published: 2010

Journal Articles

XIAP Inhibitors Present a Promising New Strategy to Sensitize Childhood Acute Leukemia Cells for Chemotherapy-Induced Apoptosis.

Sandra Löder, Melanie Fakler, Irmela Jeremias, Klaus-Michael Debatin, MD, Simone Fulda

Blood (2009) 114 (22): 3791.

https://doi.org/10.1182/blood.V114.22.3791.3791

Published: 2009

Journal Articles

A Novel Paradigm to Trigger Apoptosis in Chronic Lymphocytic Leukemia.

Sandra Loeder, Thorsten Zenz, Andrea Schnaiter, Daniel Mertens, Dirk Winkler, Hartmut Döhner, Klaus-Michael Debatin, MD, Stephan Stilgenbauer, Simone Fulda

Blood (2009) 114 (22): 731.

https://doi.org/10.1182/blood.V114.22.731.731

Published: 2009

Journal Articles

Deregulated Apoptotic Pathways Point to Effectiveness of IAP Inhibitor Therapy in Acute Myeloid Leukemia.

Sonja C Lück, Annika C Russ, Konstanze Döhner, Ursula Botzenhardt, Domagoj Vucic, Kurt Deshayes, Richard F Schlenk, Hartmut Döhner, Simone Fulda, Lars Bullinger

Blood (2009) 114 (22): 1275.

https://doi.org/10.1182/blood.V114.22.1275.1275

Published: 2009

Journal Articles

Small molecule XIAP inhibitors cooperate with TRAIL to induce apoptosis in childhood acute leukemia cells and overcome Bcl-2–mediated resistance

Melanie Fakler, Sandra Loeder, Meike Vogler, Katja Schneider, Irmela Jeremias, Klaus-Michael Debatin, Simone Fulda

Blood (2009) 113 (8): 1710–1722.

https://doi.org/10.1182/blood-2007-09-114314

Published: 2009

Includes: Supplemental data

Journal Articles

Small Molecule XIAP Inhibitors Cooperate with TRAIL to Trigger Apoptosis in Childhood Acute Leukemia Cells and Overcome Bcl-2-Mediated Resistance

Melanie Fakler, Sandra Löder, Meike Vogler, Katja Schneider, Irmela Jeremias, Klaus-Michael Debatin, MD, Simone Fulda

Blood (2008) 112 (11): 857.

https://doi.org/10.1182/blood.V112.11.857.857

Published: 2008

Journal Articles

Apoptosis Induced by Extracts of Helleborus Niger in Different Lymphoma and Leukemia Cell Lines and Primary Lymphoblasts of Children with ALL Is Independent of Smac-Overexpression and Executed Via the Mitochondrial Pathway.

Patrick Jesse, Gritt Mottke, Georg Seifert, Simone Fulda, MD, Guenter Henze, MD, Aram Prokop, PhD MD

Blood (2007) 110 (11): 4215.

https://doi.org/10.1182/blood.V110.11.4215.4215

Published: 2007

Journal Articles

Newly identified c-KIT receptor tyrosine kinase ITD in childhood AML induces ligand-independent growth and is responsive to a synergistic effect of imatinib and rapamycin

Selim Corbacioglu, Mehtap Kilic, Mike-Andrew Westhoff, Dirk Reinhardt, Simone Fulda, Klaus-Michael Debatin

Blood (2006) 108 (10): 3504–3513.

https://doi.org/10.1182/blood-2006-05-021691

Published: 2006

Journal Articles

Radiosensitization of Human Cancers by Smac Agonists.

Stavros Giagkousiklidis, BS, Meike Vogler, BS, Andrew Westhoff, PhD, Hubert Kasperczyk, BS, Klaus-Michael Debatin, MD, Simone Fulda, MD

Blood (2005) 106 (11): 1523.

https://doi.org/10.1182/blood.V106.11.1523.1523

Published: 2005

Journal Articles

Sensitization for γ-Irradiation-Induced Apoptosis by Smac.

Stavros Giagkousiklidis, MSc, Hubert Kasperczyk, MSc, Meike Vogler, MSc, Klaus-Michael Debatin, MD, Simone Fulda, MD

Blood (2004) 104 (11): 3392.

https://doi.org/10.1182/blood.V104.11.3392.3392

Published: 2004

Journal Articles

Activation of apoptosis pathways in peripheral blood lymphocytes by in vivo chemotherapy

Karsten Stahnke, Simone Fulda, Claudia Friesen, Gudrun Strauß, Klaus-Michael Debatin

Blood (2001) 98 (10): 3066–3073.

https://doi.org/10.1182/blood.V98.10.3066

Published: 2001

Journal Articles

Functional CD95 ligand and CD95 death-inducing signaling complex in activation-induced cell death and doxorubicin-induced apoptosis in leukemic T cells

Simone Fulda, Gudrun Strauss, Eric Meyer, Klaus-Michael Debatin

Blood (2000) 95 (1): 301–308.

https://doi.org/10.1182/blood.V95.1.301

Published: 2000

Journal Articles

Cross-Resistance of CD95- and Drug-Induced Apoptosis as a Consequence of Deficient Activation of Caspases (ICE/Ced-3 Proteases)

Marek Los, Ingrid Herr, Claudia Friesen, Simone Fulda, Klaus Schulze-Osthoff, Klaus-Michael Debatin

Blood (1997) 90 (8): 3118–3129.

https://doi.org/10.1182/blood.V90.8.3118

Published: 1997

NARROW

Mechanisms of Deregulation of Apoptosis in Myeloma

Biomarker of sensitivity to PR-104 in leukemia

Smac mimetic and glucocorticoids synergize to induce apoptosis in childhood ALL by promoting ripoptosome assembly

Activation of Acute Lymphocytic Leukemia Blasts with CpG ODN, IL-4 and CD40 Ligand Facilitates Enhanced Anti-Leukemic CTL Responses

XIAP Inhibitors Present a Promising New Strategy to Sensitize Childhood Acute Leukemia Cells for Chemotherapy-Induced Apoptosis.

A Novel Paradigm to Trigger Apoptosis in Chronic Lymphocytic Leukemia.

Deregulated Apoptotic Pathways Point to Effectiveness of IAP Inhibitor Therapy in Acute Myeloid Leukemia.

Small molecule XIAP inhibitors cooperate with TRAIL to induce apoptosis in childhood acute leukemia cells and overcome Bcl-2–mediated resistance

Small Molecule XIAP Inhibitors Cooperate with TRAIL to Trigger Apoptosis in Childhood Acute Leukemia Cells and Overcome Bcl-2-Mediated Resistance

Apoptosis Induced by Extracts of Helleborus Niger in Different Lymphoma and Leukemia Cell Lines and Primary Lymphoblasts of Children with ALL Is Independent of Smac-Overexpression and Executed Via the Mitochondrial Pathway.

Newly identified c-KIT receptor tyrosine kinase ITD in childhood AML induces ligand-independent growth and is responsive to a synergistic effect of imatinib and rapamycin

Radiosensitization of Human Cancers by Smac Agonists.

Sensitization for γ-Irradiation-Induced Apoptosis by Smac.

Activation of apoptosis pathways in peripheral blood lymphocytes by in vivo chemotherapy

Functional CD95 ligand and CD95 death-inducing signaling complex in activation-induced cell death and doxorubicin-induced apoptosis in leukemic T cells

Cross-Resistance of CD95- and Drug-Induced Apoptosis as a Consequence of Deficient Activation of Caspases (ICE/Ced-3 Proteases)

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American Society of Hematology

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American Society of Hematology

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