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Issue Archive

Volume 129, Issue 18
May 4 2017
Issue Cover

Table of Contents

INSIDE BLOOD COMMENTARIES

INSIDE BLOOD COMMENTARY
The importance of tying up loose (DNA) ends
Eric M. Pietras
View Articletitled, The importance of tying up loose (DNA) ends
INSIDE BLOOD COMMENTARY
FOXtrotting with PUMILIOs
Arefeh Rouhi,Florian Kuchenbauer
View Articletitled, FOXtrotting with PUMILIOs
INSIDE BLOOD COMMENTARY
RBCs pin platelets against the (thrombus) wall
Kellie R. Machlus,Elisabeth M. Battinelli
View Articletitled, RBCs pin platelets against the (thrombus) wall
INSIDE BLOOD COMMENTARY
Alzheimer disease makes new blood contacts
Mario Merlini,Katerina Akassoglou
View Articletitled, Alzheimer disease makes new blood contacts
INSIDE BLOOD COMMENTARY
Pirfenidone: a breath of fresh air for cGVHD
Parvathi Ranganathan
View Articletitled, Pirfenidone: a breath of fresh air for cGVHD

BLOOD SPOTLIGHT

How do messenger RNA splicing alterations drive myelodysplasia?
Poorval Joshi,Stephanie Halene,Omar Abdel-Wahab
View Articletitled, How do messenger RNA splicing alterations drive myelodysplasia?

CLINICAL TRIALS AND OBSERVATIONS

Efficacy and tolerability of nivolumab after allogeneic transplantation for relapsed Hodgkin lymphoma
Clinical Trials & Observations
Charles Herbaux,Jordan Gauthier,Pauline Brice,Elodie Drumez,Loic Ysebaert,Hélène Doyen,Luc Fornecker,Krimo Bouabdallah,Guillaume Manson,Hervé Ghesquières,Reza Tabrizi,Eric Hermet,Julien Lazarovici,Anne Thiebaut-Bertrand,Adrien Chauchet,Hélène Demarquette,Eileen Boyle,Roch Houot,Ibrahim Yakoub-Agha,Franck Morschhauser
View Articletitled, Efficacy and tolerability of nivolumab after allogeneic transplantation for relapsed Hodgkin lymphoma

HEMATOPOIESIS AND STEM CELLS

Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress
Wei Shi,Therese Vu,Didier Boucher,Anna Biernacka,Jules Nde,Raj K. Pandita,Jasmin Straube,Glen M. Boyle,Fares Al-Ejeh,Purba Nag,Jessie Jeffery,Janelle L. Harris,Amanda L. Bain,Marta Grzelak,Magdalena Skrzypczak,Abhishek Mitra,Norbert Dojer,Nicola Crosetto,Nicole Cloonan,Olivier J. Becherel,John Finnie,Jeffrey R. Skaar,Carl R. Walkley,Tej K. Pandita,Maga Rowicka,Krzysztof Ginalski,Steven W. Lane,Kum Kum Khanna
View Articletitled, Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress
Supplemental data
PUMILIO/FOXP1 signaling drives expansion of hematopoietic stem/progenitor and leukemia cells
Cécile Naudin,Aurore Hattabi,Fabio Michelet,Ayda Miri-Nezhad,Aissa Benyoucef,Françoise Pflumio,François Guillonneau,Serge Fichelson,Isabelle Vigon,Isabelle Dusanter-Fourt,Evelyne Lauret
View Articletitled, PUMILIO/FOXP1 signaling drives expansion of hematopoietic stem/progenitor and leukemia cells
Supplemental data

LYMPHOID NEOPLASIA

IL-4/CXCL12 loop is a key regulator of lymphoid stroma function in follicular lymphoma
Shubham Pandey,Frédéric Mourcin,Tony Marchand,Saba Nayar,Marion Guirriec,Céline Pangault,Céline Monvoisin,Patricia Amé-Thomas,Fabien Guilloton,Joelle Dulong,Mark Coles,Thierry Fest,Anja Mottok,Francesca Barone,Karin Tarte
View Articletitled, IL-4/CXCL12 loop is a key regulator of lymphoid stroma function in follicular lymphoma
Supplemental data
Acquired mutations associated with ibrutinib resistance in Waldenström macroglobulinemia
Clinical Trials & Observations
Lian Xu,Nicholas Tsakmaklis,Guang Yang,Jiaji G. Chen,Xia Liu,Maria Demos,Amanda Kofides,Christopher J. Patterson,Kirsten Meid,Joshua Gustine,Toni Dubeau,M. Lia Palomba,Ranjana Advani,Jorge J. Castillo,Richard R. Furman,Zachary R. Hunter,Steven P. Treon
View Articletitled, Acquired mutations associated with ibrutinib resistance in Waldenström macroglobulinemia
Supplemental data

MYELOID NEOPLASIA

Endoglin: a novel target for therapeutic intervention in acute leukemias revealed in xenograft mouse models
Keina M. C. Dourado,June Baik,Vanessa K. P. Oliveira,Miriam Beltrame,Ami Yamamoto,Charles P. Theuer,Camila A. V. Figueiredo,Michael R. Verneris,Rita C. R. Perlingeiro
View Articletitled, Endoglin: a novel target for therapeutic intervention in acute leukemias revealed in xenograft mouse models
Supplemental data

PLATELETS AND THROMBOPOIESIS

Elevated hematocrit enhances platelet accumulation following vascular injury
Bethany L. Walton,Marcus Lehmann,Tyler Skorczewski,Lori A. Holle,Joan D. Beckman,Jeremy A. Cribb,Micah J. Mooberry,Adam R. Wufsus,Brian C. Cooley,Jonathan W. Homeister,Rafal Pawlinski,Michael R. Falvo,Nigel S. Key,Aaron L. Fogelson,Keith B. Neeves,Alisa S. Wolberg
View Articletitled, Elevated hematocrit enhances platelet accumulation following vascular injury
Supplemental data

THROMBOSIS AND HEMOSTASIS

Depletion of coagulation factor XII ameliorates brain pathology and cognitive impairment in Alzheimer disease mice
Zu-Lin Chen,Alexey S. Revenko,Pradeep Singh,A. Robert MacLeod,Erin H. Norris,Sidney Strickland
View Articletitled, Depletion of coagulation factor XII ameliorates brain pathology and cognitive impairment in Alzheimer disease mice
Supplemental data

TRANSFUSION MEDICINE

T regulatory cells and dendritic cells protect against transfusion-related acute lung injury via IL-10
Rick Kapur,Michael Kim,Rukhsana Aslam,Mark J. McVey,Arata Tabuchi,Alice Luo,Jonathan Liu,Yuan Li,Shanjeevan Shanmugabhavananthan,Edwin R. Speck,Anne Zufferey,George Yousef,Haibo Zhang,Matthew T. Rondina,Andrew S. Weyrich,Leendert Porcelijn,Wolfgang M. Kuebler,Arthur S. Slutsky,John W. Semple
View Articletitled, T regulatory cells and dendritic cells protect against transfusion-related acute lung injury via IL-10
Supplemental data

TRANSPLANTATION

Pirfenidone ameliorates murine chronic GVHD through inhibition of macrophage infiltration and TGF-β production
Jing Du,Katelyn Paz,Ryan Flynn,Ante Vulic,Tara M. Robinson,Katie E. Lineburg,Kylie A. Alexander,Jingjing Meng,Sabita Roy,Angela Panoskaltsis-Mortari,Michael Loschi,Geoffrey R. Hill,Jonathan S. Serody,Ivan Maillard,David Miklos,John Koreth,Corey S. Cutler,Joseph H. Antin,Jerome Ritz,Kelli P. MacDonald,Timothy W. Schacker,Leo Luznik,Bruce R. Blazar
View Articletitled, Pirfenidone ameliorates murine chronic GVHD through inhibition of macrophage infiltration and TGF-β production
Supplemental data

LETTERS TO BLOOD

Ventricular arrhythmias and sudden death in patients taking ibrutinib
Clinical Trials & Observations
Benjamin L. Lampson,Lijian Yu,Robert J. Glynn,Jacqueline C. Barrientos,Eric D. Jacobsen,Versha Banerji,Jeffrey A. Jones,Renata Walewska,Kerry J. Savage,Gregory F. Michaud,Javid J. Moslehi,Jennifer R. Brown
View Articletitled, Ventricular arrhythmias and sudden death in patients taking ibrutinib
Supplemental data
More than 1 TP53 abnormality is a dominant characteristic of pure erythroid leukemia
Clinical Trials & Observations
Guillermo Montalban-Bravo,Christopher B. Benton,Sa A. Wang,Farhad Ravandi,Tapan Kadia,Jorge Cortes,Naval Daver,Koichi Takahashi,Courtney DiNardo,Elias Jabbour,Gautam Borthakur,Marina Konopleva,Sherry Pierce,Carlos Bueso-Ramos,Keyur Patel,Steven Kornblau,Hagop Kantarjian,Ken H. Young,Guillermo Garcia-Manero,Michael Andreeff
View Articletitled, More than 1 <em>TP53</em> abnormality is a dominant characteristic of pure erythroid leukemia
Supplemental data
Somatic TP53 mutations characterize preleukemic stem cells in acute myeloid leukemia
Ridhima Lal,Karin Lind,Ellen Heitzer,Peter Ulz,Kristina Aubell,Karl Kashofer,Jan M. Middeke,Christian Thiede,Eduard Schulz,Angelika Rosenberger,Sybille Hofer,Birgit Feilhauer,Beate Rinner,Vendula Svendova,Michael G. Schimek,Frank G. Rücker,Gerald Hoefler,Konstanze Döhner,Armin Zebisch,Albert Wölfler,Heinz Sill
View Articletitled, Somatic <em>TP53</em> mutations characterize preleukemic stem cells in acute myeloid leukemia
Supplemental data

BLOOD WORK

Large B-cell lymphoma variant of Richter transformation originates in pseudoproliferation centers of small lymphocytic lymphoma
Huan-You Wang
View Articletitled, Large B-cell lymphoma variant of Richter transformation originates in pseudoproliferation centers of small lymphocytic lymphoma
Triple-hit blastoid mantle cell lymphoma presenting like acute leukemia
Jie Xu,Shaoying Li
View Articletitled, Triple-hit blastoid mantle cell lymphoma presenting like acute leukemia
All Issues

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