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Emergence of BCR-ABL–specific cytotoxic T cells in the bone marrow of patients with Ph+ acute lymphoblastic leukemia during long-term imatinib mesylate treatment
Autosomal dominant and sporadic monocytopenia with susceptibility to mycobacteria, fungi, papillomaviruses, and myelodysplasia
The Mantle Cell Lymphoma International Prognostic Index (MIPI) is superior to the International Prognostic Index (IPI) in predicting survival following intensive first-line immunochemotherapy and autologous stem cell transplantation (ASCT)
Clinical-grade production of human mesenchymal stromal cells: occurrence of aneuploidy without transformation
ADAMTS13 gene deletion aggravates ischemic brain damage: a possible neuroprotective role of ADAMTS13 by ameliorating postischemic hypoperfusion
Issue Archive
February 25 2010
In this Issue
Table of Contents
INSIDE BLOOD
PLENARY PAPERS
PERSPECTIVES
Immunoglobulin heavy chain locus chromosomal translocations in B-cell precursor acute lymphoblastic leukemia: rare clinical curios or potent genetic drivers?
Martin J. S. Dyer,Takashi Akasaka,Melania Capasso,Palminder Dusanjh,Yin Fai Lee,E. Loraine Karran,Inga Nagel,Inga Vater,Gunnar Cario,Reiner Siebert
CLINICAL TRIALS AND OBSERVATIONS
Emergence of BCR-ABL–specific cytotoxic T cells in the bone marrow of patients with Ph+ acute lymphoblastic leukemia during long-term imatinib mesylate treatment
Clinical Trials & Observations
Giovanni Riva,Mario Luppi,Patrizia Barozzi,Chiara Quadrelli,Sabrina Basso,Daniela Vallerini,Eleonora Zanetti,Monica Morselli,Fabio Forghieri,Monica Maccaferri,Francesco Volzone,Cinzia Del Giovane,Roberto D'Amico,Franco Locatelli,Giuseppe Torelli,Patrizia Comoli,Leonardo Potenza
Autosomal dominant and sporadic monocytopenia with susceptibility to mycobacteria, fungi, papillomaviruses, and myelodysplasia
Clinical Trials & Observations
Donald C. Vinh,Smita Y. Patel,Gulbu Uzel,Victoria L. Anderson,Alexandra F. Freeman,Kenneth N. Olivier,Christine Spalding,Stephen Hughes,Stefania Pittaluga,Mark Raffeld,Lynn R. Sorbara,Houda Z. Elloumi,Douglas B. Kuhns,Maria L. Turner,Edward W. Cowen,Danielle Fink,Debra Long-Priel,Amy P. Hsu,Li Ding,Michelle L. Paulson,Adeline R. Whitney,Elizabeth P. Sampaio,David M. Frucht,Frank R. DeLeo,Steven M. Holland
The Mantle Cell Lymphoma International Prognostic Index (MIPI) is superior to the International Prognostic Index (IPI) in predicting survival following intensive first-line immunochemotherapy and autologous stem cell transplantation (ASCT)
Brief Report
Christian H. Geisler,Arne Kolstad,Anna Laurell,Riikka Räty,Mats Jerkeman,Mikael Eriksson,Marie Nordström,Eva Kimby,Anne Marie Boesen,Herman Nilsson-Ehle,Outi Kuittinen,Grete F. Lauritzsen,Elisabeth Ralfkiær,Mats Ehinger,Christer Sundström,Jan Delabie,Marja-Liisa Karjalainen-Lindsberg,Peter Brown,Erkki Elonen,for the Nordic Lymphoma Group
GENE THERAPY
A highly efficient short hairpin RNA potently down-regulates CCR5 expression in systemic lymphoid organs in the hu-BLT mouse model
Saki Shimizu,Patrick Hong,Balamurugan Arumugam,Lauren Pokomo,Joshua Boyer,Naoya Koizumi,Panyamol Kittipongdaja,Angela Chen,Greg Bristol,Zoran Galic,Jerome A. Zack,Otto Yang,Irvin S. Y. Chen,Benhur Lee,Dong Sung An
HEMATOPOIESIS AND STEM CELLS
Clinical-grade production of human mesenchymal stromal cells: occurrence of aneuploidy without transformation
Brief Report
Karin Tarte,Julien Gaillard,Jean-Jacques Lataillade,Loic Fouillard,Martine Becker,Hossein Mossafa,Andrei Tchirkov,Hélène Rouard,Catherine Henry,Marie Splingard,Joelle Dulong,Delphine Monnier,Patrick Gourmelon,Norbert-Claude Gorin,Luc Sensebé,on behalf of Société Française de Greffe de Moelle et Thérapie Cellulaire
IMMUNOBIOLOGY
LYMPHOID NEOPLASIA
Kinome-wide RNAi studies in human multiple myeloma identify vulnerable kinase targets, including a lymphoid-restricted kinase, GRK6
Rodger E. Tiedemann,Yuan Xiao Zhu,Jessica Schmidt,Hongwei Yin,Chang-Xin Shi,Qiang Que,Gargi Basu,David Azorsa,Louise M. Perkins,Esteban Braggio,Rafael Fonseca,P. Leif Bergsagel,Spyro Mousses,A. Keith Stewart
MYELOID NEOPLASIA
PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS
RED CELLS, IRON, AND ERYTHROPOIESIS
THROMBOSIS AND HEMOSTASIS
ADAMTS13 gene deletion aggravates ischemic brain damage: a possible neuroprotective role of ADAMTS13 by ameliorating postischemic hypoperfusion
Brief Report
Masayuki Fujioka,Kazuhide Hayakawa,Kenichi Mishima,Ai Kunizawa,Keiichi Irie,Sei Higuchi,Takafumi Nakano,Carl Muroi,Hidetada Fukushima,Mitsuhiko Sugimoto,Fumiaki Banno,Koichi Kokame,Toshiyuki Miyata,Michihiro Fujiwara,Kazuo Okuchi,Kenji Nishio
VASCULAR BIOLOGY
OTHER DEPARTMENTS
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Cover Image
Cover Image
![issue cover]()
Early postnatal mouse retina develops a stereotypic vascular pattern (top image). Systemic delivery of ALK1Fc caused a profound alteration of retinal vascular morphology (bottom image). Endothelial cell staining (green, isolectin-B4) revealed a dramatic increase in retinal vascular density, failed remodeling of the primary retinal capillary plexus into a mature vascular pattern, and defective arteriogenesis as indicated by the loss of smooth muscle actin (SMA, red). See the article by Niessen et al on page 1654.
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