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Journal Articles

Quercetin: A Novel Targeted Chemoprevention for Patients with Fanconi Anemia (FA)

Parinda A Mehta, MD, Tsuyoshi Fukuda, Junfang Zhao, Cancelas-Perez Jose, Sara Loveless, BSN, Kenneth Setchell, Alexander A. Vinks, Qishen Pang, Deborah Elder, Susan Rose, Kasiani C. Myers, MD, Adam S. Nelson, Stephanie Edwards, Adam Lane, Stella M Davies

Blood (2017) 130 (Supplement 1): 1178.

https://doi.org/10.1182/blood.V130.Suppl_1.1178.1178

Published: 2017

Journal Articles

KIT blockade is sufficient for donor hematopoietic stem cell engraftment in Fanconi anemia mice

Shanmuganathan Chandrakasan, Rajeswari Jayavaradhan, John Ernst, Archana Shrestha, Anastacia Loberg, Phillip Dexheimer, Michael Jordan, Qishen Pang, Bruce Aronow, Punam Malik

Blood (2017) 129 (8): 1048–1052.

https://doi.org/10.1182/blood-2015-12-689083

Published: 2017

Includes: Supplemental data

Journal Articles

Hyper-Active Non-Homologous End Joining Selects for Synthetic Lethality Resistant and Pathological Hematopoietic Stem Cells

Wei Du, MD, PhD, Surya Amarachintha, Wilson Andrew, Qishen Pang, PhD

Blood (2015) 126 (23): 5400.

https://doi.org/10.1182/blood.V126.23.5400.5400

Published: 2015

Journal Articles

KIT Blockade Is Sufficient to Sustain Donor Hematopoietic Stem Cell Engraftment in Fanconi Anemia Mice

Shanmuganathan Chandrakasan, MD, Rajeswari Jayavaradhan, MS, Ernst John, Archana Shrestha, MS, Phillip Dexheimer, MS, Michael B. Jordan, MD, Qishen Pang, PhD, Bruce J. Aronow, PhD, Punam Malik, MD

Blood (2015) 126 (23): 1206.

https://doi.org/10.1182/blood.V126.23.1206.1206

Published: 2015

Journal Articles

Differential Response of Fanconi Anemia Hematopoietic Stem and Progenitor Cells to Oxidative and Oncogenic Stresses

Wei Du, MD PhD, Surya Amarachintha, PhD, Erden Ozlem, Qishen Pang, PhD

Blood (2014) 124 (21): 3593.

https://doi.org/10.1182/blood.V124.21.3593.3593

Published: 2014

Journal Articles

Deletion of Fanca or Fancd2 dysregulates Treg in mice

Wei Du, Ozlem Erden, Andrew Wilson, Jared M. Sipple, Jonathan Schick, Parinda Mehta, Kasiani C. Myers, Kris A. Steinbrecher, Stella M. Davies, Qishen Pang

Blood (2014) 123 (12): 1938–1947.

https://doi.org/10.1182/blood-2013-09-528018

Published: 2014

Includes: Supplemental data

Journal Articles

Deletion Of Fanca Or Fancd2 Dysregulates Treg Activity and Exacerbates Gvhd In Mice

Wei Du, MD, PhD, Ozlem Erden, MS, Andrew Wilson, MS, Jared Sipple, Jonathan Schick, Parinda A. Mehta, Stella M. Davies, MBBS, PhD, Kris Steinbrecher, PhD, Qishen Pang, Ph.D

Blood (2013) 122 (21): 3239.

https://doi.org/10.1182/blood.V122.21.3239.3239

Published: 2013

Journal Articles

Fancd2 Deficiency Impairs Autophagy Via Deregulating The Ampk/Foxo3a/Akt Pathway

Mathieu Sertorio, Ph.D, Surya Amarachintha, Ph.D, Andrew Wilson, BS, Qishen Pang, Ph.D

Blood (2013) 122 (21): 3713.

https://doi.org/10.1182/blood.V122.21.3713.3713

Published: 2013

Journal Articles

Enhanced Notch Signaling Skews Hematopoietic Stem Cell Differentiation in Fanconi Anemia Murine Models

Wei Du, MD, PhD, Jared Sipple, Jonathan Schick, Qishen Pang, PhD

Blood (2012) 120 (21): 1191.

https://doi.org/10.1182/blood.V120.21.1191.1191

Published: 2012

Journal Articles

Salidroside stimulates DNA repair enzyme Parp-1 activity in mouse HSC maintenance

Xue Li, Jared Sipple, Qishen Pang, Wei Du

Blood (2012) 119 (18): 4162–4173.

https://doi.org/10.1182/blood-2011-10-387332

Published: 2012

Includes: Supplemental data

Journal Articles

The FA pathway counteracts oxidative stress through selective protection of antioxidant defense gene promoters

Wei Du, Reena Rani, Jared Sipple, Jonathan Schick, Kasiani C. Myers, Parinda Mehta, Paul R. Andreassen, Stella M. Davies, Qishen Pang

Blood (2012) 119 (18): 4142–4151.

https://doi.org/10.1182/blood-2011-09-381970

Published: 2012

Includes: Supplemental data

Journal Articles

FAAP20: a novel ubiquitin-binding FA nuclear core-complex protein required for functional integrity of the FA-BRCA DNA repair pathway

Abdullah Mahmood Ali, Arun Pradhan, Thiyam Ramsingh Singh, Changhu Du, Jie Li, Kebola Wahengbam, Elke Grassman, Arleen D. Auerbach, Qishen Pang, Amom Ruhikanta Meetei

Blood (2012) 119 (14): 3285–3294.

https://doi.org/10.1182/blood-2011-10-385963

Published: 2012

Includes: Supplemental data

Journal Articles

mTOR Regulates DNA Damage Response of Hematopoietic Stem and Progenitor Cells Through Modulation of Fanconi Anemia Core Complex

Fukun Guo, Jie Li, PhD, Wei Du, MD, PhD, Shuangmin Zhang, Wei Liu, M.D., M.S., George Thomas, Sara Kozma, Qishen Pang, PhD, Yi Zheng, PhD

Blood (2011) 118 (21): 864.

https://doi.org/10.1182/blood.V118.21.864.864

Published: 2011

Journal Articles

Selective Damage to Antioxidant Gene Promoters in FA Cells

Wei Du, MD, PhD, Reena Rani, Jared Sipple, Jonathan Schick, Qishen Pang, PhD

Blood (2011) 118 (21): 2413.

https://doi.org/10.1182/blood.V118.21.2413.2413

Published: 2011

Journal Articles

Increased Oxidative Stress and Genomic Instability in Peripheral Blood and Bone Marrow of Individuals with Fanconi Anemia,

Kasiani C. Myers, MD, Gretchen A Radloff, Melissa Scholz, Lisa Campbell, Jennifer E Hauser, Parinda A Mehta, MD, Robin Mueller, Lisa Vormohr, Richard E. Harris, MD, Qishen Pang, PhD, Stella M. Davies, MBBS, PhD

Blood (2011) 118 (21): 3425.

https://doi.org/10.1182/blood.V118.21.3425.3425

Published: 2011

Journal Articles

Targeting mTOR by a New Generation of Kinase Inhibitors Sensitizes Leukemia Cells for Chemotherapy Via Suppressing FANCD2 Expression

Jie Li, Fukun Guo, Jared Sipple, Sara Kozma, George Thomas, Yi Zheng, PhD, Qishen Pang, PhD

Blood (2011) 118 (21): 1514.

https://doi.org/10.1182/blood.V118.21.1514.1514

Published: 2011

Journal Articles

HSCs: stressing out over ROS

Qishen Pang

Blood (2011) 118 (11): 2932–2934.

https://doi.org/10.1182/blood-2011-07-367755

Published: 2011

Journal Articles

Overexpression of IL-3Rα on CD34 + CD38 − stem cells defines leukemia-initiating cells in Fanconi anemia AML

Wei Du, Xu-E Li, Jared Sipple, Qishen Pang

Blood (2011) 117 (16): 4243–4252.

https://doi.org/10.1182/blood-2010-09-309179

Published: 2011

Includes: Supplemental data

Journal Articles

Loss of Foxo3a In FA Mice Leads to Hematopoietic Stem Cell Exhaustion That Can Be Attenuated by Natural Anti-Oxidant Quercetin.

Jie Li, Jared Sipple, Qishen Pang, PhD

Blood (2010) 116 (21): 1166.

https://doi.org/10.1182/blood.V116.21.1166.1166

Published: 2010

Journal Articles

Overexpression of IL-3R alpha on CD34+CD38- Stem Cells Defines Leukemia-Initiating Cells In FA AML.

Wei Du, MD, PhD, Jared Sipple, Qishen Pang, PhD

Blood (2010) 116 (21): 1667.

https://doi.org/10.1182/blood.V116.21.1667.1667

Published: 2010

NARROW

Quercetin: A Novel Targeted Chemoprevention for Patients with Fanconi Anemia (FA)

KIT blockade is sufficient for donor hematopoietic stem cell engraftment in Fanconi anemia mice

Hyper-Active Non-Homologous End Joining Selects for Synthetic Lethality Resistant and Pathological Hematopoietic Stem Cells

KIT Blockade Is Sufficient to Sustain Donor Hematopoietic Stem Cell Engraftment in Fanconi Anemia Mice

Differential Response of Fanconi Anemia Hematopoietic Stem and Progenitor Cells to Oxidative and Oncogenic Stresses

Deletion of Fanca or Fancd2 dysregulates Treg in mice

Deletion Of Fanca Or Fancd2 Dysregulates Treg Activity and Exacerbates Gvhd In Mice

Fancd2 Deficiency Impairs Autophagy Via Deregulating The Ampk/Foxo3a/Akt Pathway

Enhanced Notch Signaling Skews Hematopoietic Stem Cell Differentiation in Fanconi Anemia Murine Models

Salidroside stimulates DNA repair enzyme Parp-1 activity in mouse HSC maintenance

The FA pathway counteracts oxidative stress through selective protection of antioxidant defense gene promoters

FAAP20: a novel ubiquitin-binding FA nuclear core-complex protein required for functional integrity of the FA-BRCA DNA repair pathway

mTOR Regulates DNA Damage Response of Hematopoietic Stem and Progenitor Cells Through Modulation of Fanconi Anemia Core Complex

Selective Damage to Antioxidant Gene Promoters in FA Cells

Increased Oxidative Stress and Genomic Instability in Peripheral Blood and Bone Marrow of Individuals with Fanconi Anemia,

Targeting mTOR by a New Generation of Kinase Inhibitors Sensitizes Leukemia Cells for Chemotherapy Via Suppressing FANCD2 Expression

HSCs: stressing out over ROS

Overexpression of IL-3Rα on CD34 + CD38 − stem cells defines leukemia-initiating cells in Fanconi anemia AML

Loss of Foxo3a In FA Mice Leads to Hematopoietic Stem Cell Exhaustion That Can Be Attenuated by Natural Anti-Oxidant Quercetin.

Overexpression of IL-3R alpha on CD34+CD38- Stem Cells Defines Leukemia-Initiating Cells In FA AML.

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American Society of Hematology

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American Society of Hematology

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