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Journal Articles

RNAi screen of the druggable genome identifies modulators of proteasome inhibitor sensitivity in myeloma including CDK5

Yuan Xiao Zhu, Rodger Tiedemann, Chang-Xin Shi, Holly Yin, Jessica E. Schmidt, Laura A. Bruins, Jonathan J. Keats, Esteban Braggio, Chris Sereduk, Spyro Mousses, A. Keith Stewart
Journal: Blood
Blood (2011) 117 (14): 3847–3857.
https://doi.org/10.1182/blood-2010-08-304022
Published: 2011
Includes: Supplemental data
Journal Articles

Kinome-wide RNAi studies in human multiple myeloma identify vulnerable kinase targets, including a lymphoid-restricted kinase, GRK6

Rodger E. Tiedemann, Yuan Xiao Zhu, Jessica Schmidt, Hongwei Yin, Chang-Xin Shi, Qiang Que, Gargi Basu, David Azorsa, Louise M. Perkins, Esteban Braggio, Rafael Fonseca, P. Leif Bergsagel, Spyro Mousses, A. Keith Stewart
Journal: Blood
Blood (2010) 115 (8): 1594–1604.
https://doi.org/10.1182/blood-2009-09-243980
Published: 2010
Includes: Supplemental data
Journal Articles

Achilles Heel Molecular Vulnerabilities in Multiple Myeloma Identified From Genome-Scale RNA Interference Screening.

Rodger E. Tiedemann, MBChB, PhD, FRACP, FRCPA, Yuan Xiao Zhu, Jessica Schmidt, BS, Chang-Xin Shi, Hongwei Yin, PhD, Spyro Mousses, PhD, A. Keith Stewart, MD
Journal: Blood
Blood (2009) 114 (22): 2801.
https://doi.org/10.1182/blood.V114.22.2801.2801
Published: 2009
Journal Articles

Kinome-Wide RNAi Studies in Human Multiple Myeloma Identify a Lymphoid Restricted Kinase GRK6 as a Selectively Vulnerable Target That Regulates STAT3/MCL1.

Rodger E. Tiedemann, MBChB, PhD, FRACP, FRCPA, Yuan Xiao Zhu, Jessica Schmidt, BS, Hongwei Yin, PhD, Quick Que, PhD, David Azorsa, PhD, Louise M. Perkins, PhD, Esteban Braggio, PhD, Craig B. Reeder, MD, Rafael Fonseca, MD, P. Leif Bergsagel, MD, Spyro Mousses, PhD, A. Keith Stewart, MD
Journal: Blood
Blood (2009) 114 (22): 601.
https://doi.org/10.1182/blood.V114.22.601.601
Published: 2009
Journal Articles

RNAi Screen of the Druggable Genome Identifies Modulators of Proteasome Inhibitor Sensitivity in Myeloma Including CDK5.

Yuan Xiao Zhu, PhD, Rodger E. Tiedemann, MBChB, PhD, FRACP, FRCPA, Chang-Xin Shi, PhD, Jessica Schmidt, BS, Laura Bruins, Jonathan J Keats, PhD, Holly Yin, PhD, Chris Sereduk, Spyro Mousses, PhD, A. Keith Stewart, MBChB
Journal: Blood
Blood (2009) 114 (22): 602.
https://doi.org/10.1182/blood.V114.22.602.602
Published: 2009
Journal Articles

Identification of Sensitizing Targets to the Hypomethylating Agent 5-Azacytidine in Acute Myeloid Leukemia Cells Using RNAi-Based Functional Genomics Screening

Raoul Tibes, MD, PhD, Ashish Choudhary, PhD, Amanda Henrichs, BS, Sadia Guled, BS, Irma Monzon, BS, Lourdes Peralta, BS, Spyro Mousses, PhD, David Azorsa, PhD
Journal: Blood
Blood (2008) 112 (11): 2665.
https://doi.org/10.1182/blood.V112.11.2665.2665
Published: 2008
Journal Articles

The Multiple Myeloma Research Consortium Genomics Initiative.

Jeffrey Trent, PhD, John Carpten, PhD, Michael Reich, PhD, Ted Liefeld, PhD, Jonathan Keats, PhD, Spyro Mousses, PhD, William Hahn, MD, PhD, Suzanne Trudel, MD, David Siegel, PhD, S. Vincent Rajkumar, MD, Melissa Alsina, MD, Paul Richardson, MD, Kenneth Anderson, MD, Daniel Auclair, PhD, Louise M. Perkins, PhD, Kathy Giusti, Rafael Fonseca, MD, Todd R. Golub, MD
Journal: Blood
Blood (2007) 110 (11): 2498.
https://doi.org/10.1182/blood.V110.11.2498.2498
Published: 2007
Journal Articles

Kinome and Druggable Genome Vulnerabilities in Multiple Myeloma Identified by Systematic RNA Interference Screening.

Rodger E. Tiedemann, MD, PhD, Yuan-Xiao Zhu, PhD, Holly Yin, PhD, Quick Que, PhD, Chang-Xin Shi, PhD, Spyro Mousses, PhD, Keith Stewart, MD
Journal: Blood
Blood (2007) 110 (11): 391.
https://doi.org/10.1182/blood.V110.11.391.391
Published: 2007
Journal Articles

RNAi Screen of the Druggable Genome To Identify Modulators of Bortezomib in Myeloma.

Yuan Xiao Zhu, PhD, Holly Yin, Ph.D., Qiang Que, Ph.D., Rodger E. Tiedemann, M.D., Ph.D., Wee-Joo Chng, M.D., Chang Xin Shi, Ph.D., Spyro Mousses, Ph.D, Keith Stewart, M.D
Journal: Blood
Blood (2007) 110 (11): 2478.
https://doi.org/10.1182/blood.V110.11.2478.2478
Published: 2007
Journal Articles

Mathematical Models To Identify Combined Protein and Clinical Biomarkers of Response to Induction Chemotherapy in Acute Myeloid Leukemia (AML).

Raoul Tibes, MD, PhD, Natalie Meurice, PhD, Steven P. Anthony, DO, YiHua Qiu, PhD, Steven M. Kornblau, MD, Spyro Mousses, PhD, Joachim Petit, PhD
Journal: Blood
Blood (2007) 110 (11): 2399.
https://doi.org/10.1182/blood.V110.11.2399.2399
Published: 2007
Journal Articles

A Comprehensive Study of Chromosome 13 Abnormalities (Δ 13) in Multiple Myeloma Using High-Throughput, Array-Based Methods.

Angela S. Baker, Ph.D., Tammy Price-Troska, Michael L. Bittner, Ph.D., Scott A. Van Wier, Rachel Rempel, Gregory J. Ahmann, Tyler S. Pidgeon, Spyro Mousses, Ph.D., Bernie Futscher, Ph.D., Rafael D. Fonseca, M.D., John D. Carpten, Ph.D.
Journal: Blood
Blood (2004) 104 (11): 1417.
https://doi.org/10.1182/blood.V104.11.1417.1417
Published: 2004