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Journal Articles

Preclinical Development of AT1412, a Patient Derived CD9 Antibody That Does Not Induce Thrombosis for Treatment of B ALL

Remko Schotte, Julien Villaudy, PhD, Greta De Jong, MD, Viviana Neviani, PhD, Wouter Pos, PhD, Sophie E Levie, Daniel M Go, Etsuko Yasuda, PhD, Esmay Frankin, Madalina Cercel, Susan E van Hal-van Veen, Dorien van de Berg, Anikó Szabó, MD, Christien Fatmawati, Martijn Kedde, PhD, Yvonne Claassen, Sjeng Horbach, PhD, Anita W Rijneveld, MD PhD, Piet Gros, prof, Hergen Spits, prof, Mette D Hazenberg, MD PhD, Hans van Eenennaam, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 41–42.
https://doi.org/10.1182/blood-2020-134088
Published: 2020
Journal Articles

AT1412, a Patient-Derived Antibody in Development for the Treatment of CD9 Positive Precursor B-Acute Lymphoblastic Leukemia

Greta De Jong, Sophie E Levie, Remko Schotte, PhD, Wouter Pos, PhD, Daniel Go, Etsuko Yasuda, Madalina Cercel, Susan E van Hal-van Veen, Esmay Frankin, Anikó Szabó, MD, Julien Villaudy, PhD, Pauline M van Helden, PhD, Hans van Eenennaam, PhD, Hergen Spits, PhD, Anita W Rijneveld, MD PhD, Mette D Hazenberg, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4461.
https://doi.org/10.1182/blood-2019-127894
Published: 2019
Journal Articles

The macrophage mannose receptor promotes uptake of ADAMTS13 by dendritic cells

Nicoletta Sorvillo, Wouter Pos, Linda M. van den Berg, Rob Fijnheer, Luisa Martinez-Pomares, Teunis B. Geijtenbeek, Eszter Herczenik, Jan Voorberg
Journal: Blood
Blood (2012) 119 (16): 3828–3835.
https://doi.org/10.1182/blood-2011-09-377754
Published: 2012
Includes: Supplemental data
Journal Articles

C-Type Lectin Receptor Mediated Immune Recognition of ADAMTS13 Promotes HLA-DRB1*11 Dependent Presentation of CUB1-2 Derived Peptides by Dendritic Cells

Nicoletta Sorvillo, Simon D van Haren, Wouter Pos, Eszter Herczenik, Rob Fijnheer, Luisa Martinez-Pomares, Teunis B Geijtenbeek, Alexander B Meijer, Jan Voorberg
Journal: Blood
Blood (2011) 118 (21): 196.
https://doi.org/10.1182/blood.V118.21.196.196
Published: 2011
Journal Articles

IgG Antibodies Directed towards a Single Antigenic Surface In the Spacer Domain of ADAMTS13 Predominate In Plasma of Patients with Acquired TTP.

Wouter Pos, Rob Fijnheer, Gestur Vidarsson, Jan Voorberg
Journal: Blood
Blood (2010) 116 (21): 1438.
https://doi.org/10.1182/blood.V116.21.1438.1438
Published: 2010
Journal Articles

An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS13 spacer domain identifies a binding site for the A2 domain of VWF

Wouter Pos, James T. B. Crawley, Rob Fijnheer, Jan Voorberg, David A. Lane, Brenda M. Luken
Journal: Blood
Blood (2010) 115 (8): 1640–1649.
https://doi.org/10.1182/blood-2009-06-229203
Published: 2010
Journal Articles

Critical Amino Acids in a Conserved Region of the Spacer Domain Contributing to the Binding of Anti-ADAMTS13 Antibodies

Wouter Pos, M.Sc., Brenda M. Luken, Ph.D., Ellen A.M. Turenhout, Bas de Laat, Ph.D., Rob Fijnheer, Ph.D./M.D., Jan Voorberg, Ph.D.
Journal: Blood
Blood (2008) 112 (11): 275.
https://doi.org/10.1182/blood.V112.11.275.275
Published: 2008
Journal Articles

Human Antibodies with Specificity for the Spacer Domain of ADAMTS13 Are Derived from VH1-69 Germline Genes.

Wouter Pos, MSc, Brenda M. Luken, PhD, Johanna Kremer-Hovinga, MD, PhD, Ellen A.M. Turenhout, Roy Jefferis, PhD, Jing-fei Dong, MD, PhD, Rob Fijnheer, MD, PhD, Jan Voorberg, PhD
Journal: Blood
Blood (2007) 110 (11): 2158.
https://doi.org/10.1182/blood.V110.11.2158.2158
Published: 2007
Journal Articles

Beta2-Glycoprotein I: Implications for a Regulatory Role in Thrombotic Thrombocytopenic Purpura.

Bas de Laat, PhD, Johanna A. Kremer Hovinga, MD, PhD, Wouter Pos, Evelyn Groot, Jing-Fei Dong, MD, PhD, Bernard Lammle, MD, PhD, Jan Voorberg, PhD, Philip G. de Groot, PhD
Journal: Blood
Blood (2007) 110 (11): 278.
https://doi.org/10.1182/blood.V110.11.278.278
Published: 2007