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Issue Archive

Volume 114, Issue 1
July 2 2009
Issue Cover

Table of Contents

INSIDE BLOOD

CLINICAL TRIALS AND OBSERVATIONS
Iron overload in Asia
Clinical Trials & Observations
Chaim Hershko
View Articletitled, Iron overload in Asia
IMMUNOBIOLOGY
“Self”-reflection by KIR
Sarah Cooley,Jeffrey S. Miller
View Articletitled, “Self”-reflection by KIR
INSIDE BLOOD
Mighty mouse
Amy J. Johnson
View Articletitled, Mighty mouse
PLATELETS AND THROMBOPOIESIS
Megakaryocytes survive without survivin
Katya Ravid
View Articletitled, Megakaryocytes survive without survivin

BLOOD WORK

Granulocytic sarcoma
View Articletitled, Granulocytic sarcoma

REVIEW ARTICLES

Quality of life after allogeneic hematopoietic cell transplantation
Joseph Pidala,Claudio Anasetti,Heather Jim
View Articletitled, Quality of life after allogeneic hematopoietic cell transplantation

CLINICAL TRIALS AND OBSERVATIONS

Iron overload in the Asian community
Clinical Trials & Observations
Chun Yu Lok,Alison T. Merryweather-Clarke,Vip Viprakasit,Yingyong Chinthammitr,Somdet Srichairatanakool,Chanin Limwongse,David Oleesky,Anthony J. Robins,John Hudson,Phyu Wai,Anuja Premawardhena,H. Janaka de Silva,Anuradha Dassanayake,Carole McKeown,Maurice Jackson,Rousseau Gama,Nasaim Khan,William Newman,Gurvinder Banait,Andrew Chilton,Isaac Wilson-Morkeh,David J. Weatherall,Kathryn J.H. Robson
View Articletitled, Iron overload in the Asian community
Supplemental data
The immunoglobulin gene repertoire of low-count chronic lymphocytic leukemia (CLL)–like monoclonal B lymphocytosis is different from CLL: diagnostic implications for clinical monitoring
Clinical Trials & Observations
Antonis Dagklis,Claudia Fazi,Cinzia Sala,Valeria Cantarelli,Cristina Scielzo,Roberto Massacane,Daniela Toniolo,Federico Caligaris-Cappio,Kostas Stamatopoulos,Paolo Ghia
View Articletitled, The immunoglobulin gene repertoire of low-count chronic lymphocytic leukemia (CLL)–like monoclonal B lymphocytosis is different from CLL: diagnostic implications for clinical monitoring
Increased frequency (12%) of circulating chronic lymphocytic leukemia–like B-cell clones in healthy subjects using a highly sensitive multicolor flow cytometry approach
Brief Report
Wendy G. Nieto,Julia Almeida,Alfonso Romero,Cristina Teodosio,Antonio López,Ana F. Henriques,Maria Luz Sánchez,María Jara-Acevedo,Ana Rasillo,Marcos González,Paulino Fernández-Navarro,Tomás Vega,Alberto Orfao,the Primary Health Care Group of Salamanca for the Study of MBL
View Articletitled, Increased frequency (12%) of circulating chronic lymphocytic leukemia–like B-cell clones in healthy subjects using a highly sensitive multicolor flow cytometry approach
Supplemental data
The relationship between the serum free light chain assay and serum immunofixation electrophoresis, and the definition of concordant and discordant free light chain ratios
Brief Report
Seema Singhal,Eric Vickrey,Jairam Krishnamurthy,Veerpal Singh,Sharon Allen,Jayesh Mehta
View Articletitled, The relationship between the serum free light chain assay and serum immunofixation electrophoresis, and the definition of concordant and discordant free light chain ratios

HEMATOPOIESIS AND STEM CELLS

C/EBPα initiates primitive myelopoiesis in pluripotent embryonic cells
Yaoyao Chen,Ricardo M. B. Costa,Nick R. Love,Ximena Soto,Martin Roth,Roberto Paredes,Enrique Amaya
View Articletitled, C/EBPα initiates primitive myelopoiesis in pluripotent embryonic cells
Supplemental data
Thrombin-cleaved osteopontin regulates hemopoietic stem and progenitor cell functions through interactions with α9β1 and α4β1 integrins
Jochen Grassinger,David N. Haylock,Melonie J. Storan,Gemma O. Haines,Brenda Williams,Genevieve A. Whitty,Andrew R. Vinson,Cheang Ly Be,Songhui Li,Esben S. Sørensen,Patrick P.L. Tam,David T. Denhardt,Dean Sheppard,Peter F. Choong,Susan K. Nilsson
View Articletitled, Thrombin-cleaved osteopontin regulates hemopoietic stem and progenitor cell functions through interactions with α<sub>9</sub>β<sub>1</sub> and α<sub>4</sub>β<sub>1</sub> integrins
Expression of Scl in mesoderm rescues hematopoiesis in the absence of Oct-4
Brief Report
Kimi Y. Kong,Elizabeth A. Williamson,Jason H. Rogers,Tam Tran,Robert Hromas,Richard Dahl
View Articletitled, Expression of Scl in mesoderm rescues hematopoiesis in the absence of Oct-4
Supplemental data

IMMUNOBIOLOGY

Identification of crassin acetate as a new immunosuppressant triggering heme oxygenase-1 expression in dendritic cells
Hironori Matsushima,Hiroaki Tanaka,Norikatsu Mizumoto,Akira Takashima
View Articletitled, Identification of crassin acetate as a new immunosuppressant triggering heme oxygenase-1 expression in dendritic cells
Supplemental data
The importance of Src homology 2 domain-containing leukocyte phosphoprotein of 76 kilodaltons sterile-α motif domain in thymic selection and T-cell activation
Shudan Shen,Jasmine Lau,Minghua Zhu,Jianwei Zou,Deirdre Fuller,Qi-jing Li,Weiguo Zhang
View Articletitled, The importance of Src homology 2 domain-containing leukocyte phosphoprotein of 76 kilodaltons sterile-α motif domain in thymic selection and T-cell activation
HIV-1–infected dendritic cells show 2 phases of gene expression changes, with lysosomal enzyme activity decreased during the second phase
Andrew N. Harman,Marianne Kraus,Chris R. Bye,Karen Byth,Stuart G. Turville,Owen Tang,Sarah K. Mercier,Najla Nasr,Josh L. Stern,Barry Slobedman,Christoph Driessen,Anthony L. Cunningham
View Articletitled, HIV-1–infected dendritic cells show 2 phases of gene expression changes, with lysosomal enzyme activity decreased during the second phase
Supplemental data
KIR acquisition probabilities are independent of self-HLA class I ligands and increase with cellular KIR expression
Sandra Andersson,Cyril Fauriat,Jenny-Ann Malmberg,Hans-Gustaf Ljunggren,Karl-Johan Malmberg
View Articletitled, KIR acquisition probabilities are independent of self-HLA class I ligands and increase with cellular KIR expression
Supplemental data
Early defects in human T-cell development severely affect distribution and maturation of thymic stromal cells: possible implications for the pathophysiology of Omenn syndrome
Brief Report
Pietro Luigi Poliani,Fabio Facchetti,Maria Ravanini,Andrew Richard Gennery,Anna Villa,Chaim M. Roifman,Luigi D. Notarangelo
View Articletitled, Early defects in human T-cell development severely affect distribution and maturation of thymic stromal cells: possible implications for the pathophysiology of Omenn syndrome
Supplemental data

LYMPHOID NEOPLASIA

EBV Zta protein induces the expression of interleukin-13, promoting the proliferation of EBV-infected B cells and lymphoblastoid cell lines
Shu-Chun Tsai,Sue-Jane Lin,Po-Wen Chen,Wen-Yi Luo,Te-Huei Yeh,Hsei-Wei Wang,Chi-Ju Chen,Ching-Hwa Tsai
View Articletitled, EBV Zta protein induces the expression of interleukin-13, promoting the proliferation of EBV-infected B cells and lymphoblastoid cell lines
A mouse model for chronic lymphocytic leukemia based on expression of the SV40 large T antigen
Petra J. ter Brugge,Van B. T. Ta,Marjolein J. W. de Bruijn,Guido Keijzers,Alex Maas,Dik C. van Gent,Rudi W. Hendriks
View Articletitled, A mouse model for chronic lymphocytic leukemia based on expression of the SV40 large T antigen
Supplemental data
Induction of angiogenesis by normal and malignant plasma cells
Dirk Hose,Jérôme Moreaux,Tobias Meissner,Anja Seckinger,Hartmut Goldschmidt,Axel Benner,Karène Mahtouk,Jens Hillengass,Thierry Rème,John De Vos,Michael Hundemer,Maud Condomines,Uta Bertsch,Jean-François Rossi,Anna Jauch,Bernard Klein,Thomas Möhler
View Articletitled, Induction of angiogenesis by normal and malignant plasma cells
Supplemental data

MYELOID NEOPLASIA

Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies
Brief Report
Omar Abdel-Wahab,Ann Mullally,Cyrus Hedvat,Guillermo Garcia-Manero,Jay Patel,Martha Wadleigh,Sebastien Malinge,JinJuan Yao,Outi Kilpivaara,Rukhmi Bhat,Kety Huberman,Sabrena Thomas,Igor Dolgalev,Adriana Heguy,Elisabeth Paietta,Michelle M. Le Beau,Miloslav Beran,Martin S. Tallman,Benjamin L. Ebert,Hagop M. Kantarjian,Richard M. Stone,D. Gary Gilliland,John D. Crispino,Ross L. Levine
View Articletitled, Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies
Supplemental data
Molecular stratification model for prognosis in cytogenetically normal acute myeloid leukemia
Brief Report
Carlos M. Santamaría,María C. Chillón,Ramón García-Sanz,Cristina Pérez,María D. Caballero,Fernando Ramos,Alfonso García de Coca,José M. Alonso,Pilar Giraldo,Teresa Bernal,José A. Queizán,Juan N. Rodriguez,Pascual Fernández-Abellán,Abelardo Bárez,María J. Peñarrubia,Ana Balanzategui,María B. Vidriales,María E. Sarasquete,Miguel Alcoceba,Joaquín Díaz-Mediavilla,Jesús F. San Miguel,Marcos Gonzalez
View Articletitled, Molecular stratification model for prognosis in cytogenetically normal acute myeloid leukemia

PLATELETS AND THROMBOPOIESIS

Survivin is not required for the endomitotic cell cycle of megakaryocytes
Brief Report
Qiang Wen,Cindy Leung,Zan Huang,Sara Small,Alagarsamy Lakku Reddi,Jonathan D. Licht,John D. Crispino
View Articletitled, Survivin is not required for the endomitotic cell cycle of megakaryocytes
Supplemental data
Platelet membrane proteomics: a novel repository for functional research
e-blood
Urs Lewandrowski,Stefanie Wortelkamp,Katharina Lohrig,René P. Zahedi,Dirk A. Wolters,Ulrich Walter,Albert Sickmann
View Articletitled, Platelet membrane proteomics: a novel repository for functional research
Supplemental data

RED CELLS, IRON, AND ERYTHROPOIESIS

Mitochondrial clearance is regulated by Atg7-dependent and -independent mechanisms during reticulocyte maturation
Ji Zhang,Mindy S. Randall,Melanie R. Loyd,Frank C. Dorsey,Mondira Kundu,John L. Cleveland,Paul A. Ney
View Articletitled, Mitochondrial clearance is regulated by Atg7-dependent and -independent mechanisms during reticulocyte maturation
Supplemental data
GATA-1 associates with and inhibits p53
Cecelia D. Trainor,Caroline Mas,Patrick Archambault,Paola Di Lello,James G. Omichinski
View Articletitled, GATA-1 associates with and inhibits p53
Supplemental data
Impaired FANCD2 monoubiquitination and hypersensitivity to camptothecin uniquely characterize Fanconi anemia complementation group M
Thiyam Ramsing Singh,Sietske T. Bakker,Sheba Agarwal,Michael Jansen,Elke Grassman,Barbara C. Godthelp,Abdullah Mahmood Ali,Chang-hu Du,Martin A. Rooimans,Qiang Fan,Kebola Wahengbam,Jurgen Steltenpool,Paul R. Andreassen,David A. Williams,Hans Joenje,Johan P. de Winter,Amom Ruhikanta Meetei
View Articletitled, Impaired FANCD2 monoubiquitination and hypersensitivity to camptothecin uniquely characterize Fanconi anemia complementation group M
Supplemental data
Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells
Toshihiko Tanno,Prashanth Porayette,Orapan Sripichai,Seung-Jae Noh,Colleen Byrnes,Ajoy Bhupatiraju,Y. Terry Lee,Julia B. Goodnough,Omid Harandi,Tomas Ganz,Robert F. Paulson,Jeffery L. Miller
View Articletitled, Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells
Supplemental data
SCF induces γ-globin gene expression by regulating downstream transcription factor COUP-TFII
Wulin Aerbajinai,Jianqiong Zhu,Chutima Kumkhaek,Kyung Chin,Griffin P. Rodgers
View Articletitled, SCF induces γ-globin gene expression by regulating downstream transcription factor COUP-TFII
Supplemental data

THROMBOSIS AND HEMOSTASIS

Structural and therapeutic insights from the species specificity and in vivo antithrombotic activity of a novel αIIb-specific αIIbβ3 antagonist
Robert Blue,M. Anna Kowalska,Jessica Hirsch,Marta Murcia,Christin A. Janczak,Amanda Harrington,Marketa Jirouskova,Jihong Li,Rudy Fuentes,Michael A. Thornton,Marta Filizola,Mortimer Poncz,Barry S. Coller
View Articletitled, Structural and therapeutic insights from the species specificity and in vivo antithrombotic activity of a novel αIIb-specific αIIbβ3 antagonist
Supplemental data

TRANSPLANTATION

A chromosome 16 quantitative trait locus regulates allogeneic bone marrow engraftment in nonmyeloablated mice
Thai M. Cao,Alun Thomas,Yuanyuan Wang,Schickwann Tsai,Kathryn Logronio,Judith A. Shizuru
View Articletitled, A chromosome 16 quantitative trait locus regulates allogeneic bone marrow engraftment in nonmyeloablated mice
Supplemental data
Hematopoietic stem cell transplantation in Griscelli syndrome type 2: a single-center report on 10 patients
Jana Pachlopnik Schmid,Despina Moshous,Nathalie Boddaert,Bénédicte Neven,Liliane Dal Cortivo,Marc Tardieu,Marina Cavazzana-Calvo,Stéphane Blanche,Geneviève de Saint Basile,Alain Fischer
View Articletitled, Hematopoietic stem cell transplantation in Griscelli syndrome type 2: a single-center report on 10 patients
Supplemental data
Cellular senescence of white blood cells in very long-term survivors after allogeneic hematopoietic stem cell transplantation: the role of chronic graft-versus-host disease and female donor sex
Brief Report
Gabriela M. Baerlocher,Alicia Rovó,Astrid Müller,Sybille Matthey,Martin Stern,Jörg Halter,Dominik Heim,Johannes Rischewski,Alois Gratwohl,André Tichelli
View Articletitled, Cellular senescence of white blood cells in very long-term survivors after allogeneic hematopoietic stem cell transplantation: the role of chronic graft-versus-host disease and female donor sex

CORRESPONDENCE

Plasma quantitation of JAK2 mutation is not suitable as a clinical test: an artifact of storage
Mohamed E. Salama,Sabina I. Swierczek,Kimberly Hickman,Andrew Wilson,Josef T. Prchal
View Articletitled, Plasma quantitation of JAK2 mutation is not suitable as a clinical test: an artifact of storage
Response:Plasma and JAK2 mutation
Maher Albitar,Wanlong Ma,Hagop Kantarjian,Francis Giles
View Articletitled, Response:Plasma and JAK2 mutation
Incidence of second cancers after allogeneic hematopoietic stem cell transplantation using reduced-dose radiation
Matthew M. Hsieh,Courtney D. Fitzhugh,John F. Tisdale
View Articletitled, Incidence of second cancers after allogeneic hematopoietic stem cell transplantation using reduced-dose radiation
Response:Solid cancers after allogeneic hematopoietic cell transplantation
J. Douglas Rizzo,Rochelle E. Curtis,H. Joachim Deeg,Lois B. Travis,on behalf of the coauthors
View Articletitled, Response:Solid cancers after allogeneic hematopoietic cell transplantation

ERRATUM

Skovseth et al. Endostatin dramatically inhibits endothelial cell migration, vascular morphogenesis, and perivascular cell recruitment in vivo. Blood. 2005;105(3):1044-1051.
View Articletitled, Skovseth et al. Endostatin dramatically inhibits endothelial cell migration, vascular morphogenesis, and perivascular cell recruitment in vivo. <em>Blood</em>. 2005;105(3):1044-1051.
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