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Issue Archive

Volume 113, Issue 6
February 5 2009
Issue Cover

Table of Contents

INSIDE BLOOD

IMMUNOBIOLOGY
Integrating integrins into HIV pathogenesis
Andrea Lisco,Leonid Margolis
View Articletitled, Integrating integrins into HIV pathogenesis
HEMATOPOIESIS & STEM CELLS
Is TGF-β a stemness regulator?
Stefan Karlsson
View Articletitled, Is TGF-β a stemness regulator?
INSIDE BLOOD
ROMA illuminates CLL genomic lesions
Federico Caligaris-Cappio
View Articletitled, ROMA illuminates CLL genomic lesions

BLOOD WORK

Parasternal mass
View Articletitled, Parasternal mass

REVIEW ARTICLES

HIV-associated lymphomas and gamma-herpesviruses
Antonino Carbone,Ethel Cesarman,Michele Spina,Annunziata Gloghini,Thomas F. Schulz
View Articletitled, HIV-associated lymphomas and gamma-herpesviruses

CLINICAL TRIALS AND OBSERVATIONS

Clinical relevance of decreased free protein S levels: results from a retrospective family cohort study involving 1143 relatives
Clinical Trials & Observations
Willem M. Lijfering,Rene Mulder,Min Ki ten Kate,Nic J. G. M. Veeger,Andre B. Mulder,Jan van der Meer
View Articletitled, Clinical relevance of decreased free protein S levels: results from a retrospective family cohort study involving 1143 relatives
Effects of eradication of Helicobacter pylori infection in patients with immune thrombocytopenic purpura: a systematic review
Clinical Trials & Observations
Roberto Stasi,Ameet Sarpatwari,Jodi B. Segal,John Osborn,Maria Laura Evangelista,Nichola Cooper,Drew Provan,Adrian Newland,Sergio Amadori,James B. Bussel
View Articletitled, Effects of eradication of <em>Helicobacter pylori</em> infection in patients with immune thrombocytopenic purpura: a systematic review

HEMATOPOIESIS AND STEM CELLS

Zebrafish runx1 promoter-EGFP transgenics mark discrete sites of definitive blood progenitors
Enid Yi Ni Lam,Jackie Y. M. Chau,Maggie L. Kalev-Zylinska,Timothy M. Fountaine,R. Scott Mead,Christopher J. Hall,Philip S. Crosier,Kathryn E. Crosier,Maria Vega Flores
View Articletitled, Zebrafish <em>runx1</em> promoter-EGFP transgenics mark discrete sites of definitive blood progenitors
Supplemental data
TGF-β as a candidate bone marrow niche signal to induce hematopoietic stem cell hibernation
Satoshi Yamazaki,Atsushi Iwama,Shin-ichiro Takayanagi,Koji Eto,Hideo Ema,Hiromitsu Nakauchi
View Articletitled, TGF-β as a candidate bone marrow niche signal to induce hematopoietic stem cell hibernation
Supplemental data

IMMUNOBIOLOGY

Distinctive localization of antigen-presenting cells in human lymph nodes
Catherine E. Angel,Chun-Jen J. Chen,Oliver C. Horlacher,Sintia Winkler,Thomas John,Judy Browning,Duncan MacGregor,Jonathan Cebon,P. Rod Dunbar
View Articletitled, Distinctive localization of antigen-presenting cells in human lymph nodes
Supplemental data
PRELI is a mitochondrial regulator of human primary T-helper cell apoptosis, STAT6, and Th2-cell differentiation
Johanna Tahvanainen,Teemu Kallonen,Hanna Lähteenmäki,Kaisa M. Heiskanen,Jukka Westermarck,Kanury V. S. Rao,Riitta Lahesmaa
View Articletitled, PRELI is a mitochondrial regulator of human primary T-helper cell apoptosis, STAT6, and Th2-cell differentiation
Cell adhesion through αV-containing integrins is required for efficient HIV-1 infection in macrophages
Ester Ballana,Eduardo Pauls,Jordi Senserrich,Bonaventura Clotet,Françoise Perron-Sierra,Gordon C. Tucker,José A. Esté
View Articletitled, Cell adhesion through αV-containing integrins is required for efficient HIV-1 infection in macrophages
Supplemental data

LYMPHOID NEOPLASIA

Effective treatment of a murine model of adult T-cell leukemia using depsipeptide and its combination with unmodified daclizumab directed toward CD25
Jing Chen,Meili Zhang,Wei Ju,Thomas A. Waldmann
View Articletitled, Effective treatment of a murine model of adult T-cell leukemia using depsipeptide and its combination with unmodified daclizumab directed toward CD25
Novel genomic alterations and clonal evolution in chronic lymphocytic leukemia revealed by representational oligonucleotide microarray analysis (ROMA)
Vladimir Grubor,Alex Krasnitz,Jennifer E. Troge,Jennifer L. Meth,B. Lakshmi,Jude T. Kendall,Boris Yamrom,Garrick Alex,Deepa Pai,Nicholas Navin,Lisa A. Hufnagel,Yoon-Ha Lee,Kerry Cook,Steven L. Allen,Kanti R. Rai,Rajendra N. Damle,Carlo Calissano,Nicholas Chiorazzi,Michael Wigler,Diane Esposito
View Articletitled, Novel genomic alterations and clonal evolution in chronic lymphocytic leukemia revealed by representational oligonucleotide microarray analysis (ROMA)
Supplemental data

MYELOID NEOPLASIA

Oncogenic Kras-induced leukemogeneis: hematopoietic stem cells as the initial target and lineage-specific progenitors as the potential targets for final leukemic transformation
Jing Zhang,Jing Wang,Yangang Liu,Harwin Sidik,Ken H. Young,Harvey F. Lodish,Mark D. Fleming
View Articletitled, Oncogenic <em>Kras</em>-induced leukemogeneis: hematopoietic stem cells as the initial target and lineage-specific progenitors as the potential targets for final leukemic transformation
Supplemental data
Aberrant DNA methylation is a dominant mechanism in MDS progression to AML
Ying Jiang,Andrew Dunbar,Lukasz P. Gondek,Sanjay Mohan,Manjot Rataul,Christine O'Keefe,Mikkael Sekeres,Yogen Saunthararajah,Jaroslaw P. Maciejewski
View Articletitled, Aberrant DNA methylation is a dominant mechanism in MDS progression to AML

PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS

BK channels in innate immune functions of neutrophils and macrophages
Kirill Essin,Maik Gollasch,Susanne Rolle,Patrick Weissgerber,Matthias Sausbier,Erwin Bohn,Ingo B. Autenrieth,Peter Ruth,Friedrich C. Luft,William M. Nauseef,Ralph Kettritz
View Articletitled, BK channels in innate immune functions of neutrophils and macrophages
Supplemental data

PLATELETS AND THROMBOPOIESIS

Lactadherin and clearance of platelet-derived microvesicles
Swapan K. Dasgupta,Hanan Abdel-Monem,Polly Niravath,Anhquyen Le,Ricardo V. Bellera,Kimberly Langlois,Shigekazu Nagata,Rolando E. Rumbaut,Perumal Thiagarajan
View Articletitled, Lactadherin and clearance of platelet-derived microvesicles

RED CELLS, IRON, AND ERYTHROPOIESIS

Mir-144 selectively regulates embryonic α-hemoglobin synthesis during primitive erythropoiesis
Yan-Fang Fu,Ting-Ting Du,Mei Dong,Kang-Yong Zhu,Chang-Bin Jing,Yong Zhang,Lei Wang,Hong-Bo Fan,Yi Chen,Yi Jin,Gui-Ping Yue,Sai-Juan Chen,Zhu Chen,Qiu-Hua Huang,Qing Jing,Min Deng,Ting Xi Liu
View Articletitled, Mir-144 selectively regulates embryonic α-hemoglobin synthesis during primitive erythropoiesis
Supplemental data
The monovalent cation leak in overhydrated stomatocytic red blood cells results from amino acid substitutions in the Rh-associated glycoprotein
Lesley J. Bruce,Hélène Guizouarn,Nicholas M. Burton,Nicole Gabillat,Joyce Poole,Joanna F. Flatt,R. Leo Brady,Franck Borgese,Jean Delaunay,Gordon W. Stewart
View Articletitled, The monovalent cation leak in overhydrated stomatocytic red blood cells results from amino acid substitutions in the Rh-associated glycoprotein
Supplemental data

THROMBOSIS AND HEMOSTASIS

Reduced thrombin generation increases host susceptibility to group A streptococcal infection
Hongmin Sun,Xixi Wang,Jay L. Degen,David Ginsburg
View Articletitled, Reduced thrombin generation increases host susceptibility to group A streptococcal infection

TRANSPLANTATION

In vitro–differentiated TH17 cells mediate lethal acute graft-versus-host disease with severe cutaneous and pulmonary pathologic manifestations
Michael J. Carlson,Michelle L. West,James M. Coghill,Angela Panoskaltsis-Mortari,Bruce R. Blazar,Jonathan S. Serody
View Articletitled, In vitro–differentiated TH17 cells mediate lethal acute graft-versus-host disease with severe cutaneous and pulmonary pathologic manifestations
Supplemental data
Myeloablative allogeneic versus autologous stem cell transplantation in adult patients with acute lymphoblastic leukemia in first remission: a prospective sibling donor versus no-donor comparison
Jan J. Cornelissen,Bronno van der Holt,Gregor E. G. Verhoef,Mars B. van 't Veer,Marinus H. J. van Oers,Harry C. Schouten,Gert Ossenkoppele,Pieter Sonneveld,Johan Maertens,Marinus van Marwijk Kooy,Martijn R. Schaafsma,Pierre W. Wijermans,Douwe H. Biesma,Shulamit Wittebol,Paul J. Voogt,Joke W. Baars,Pierre Zachée,Leo F. Verdonck,Bob Löwenberg,Adriaan W. Dekker,on behalf of the Dutch-Belgian HOVON Cooperative Group,on behalf of the Dutch-Belgian HOVON Cooperative Group,on behalf of the Dutch-Belgian HOVON Cooperative Group,on behalf of the Dutch-Belgian HOVON Cooperative Group,on behalf of the Dutch-Belgian HOVON Cooperative Group,on behalf of the Dutch-Belgian HOVON Cooperative Group,on behalf of the Dutch-Belgian HOVON Cooperative Group,on behalf of the Dutch-Belgian HOVON Cooperative Group,on behalf of the Dutch-Belgian HOVON Cooperative Group,on behalf of the Dutch-Belgian HOVON Cooperative Group,on behalf of the Dutch-Belgian HOVON Cooperative Group,on behalf of the Dutch-Belgian HOVON Cooperative Group,on behalf of the Dutch-Belgian HOVON Cooperative Group,on behalf of the Dutch-Belgian HOVON Cooperative Group,on behalf of the Dutch-Belgian HOVON Cooperative Group,on behalf of the Dutch-Belgian HOVON Cooperative Group,on behalf of the Dutch-Belgian HOVON Cooperative Group,on behalf of the Dutch-Belgian HOVON Cooperative Group,on behalf of the Dutch-Belgian HOVON Cooperative Group,on behalf of the Dutch-Belgian HOVON Cooperative Group
View Articletitled, Myeloablative allogeneic versus autologous stem cell transplantation in adult patients with acute lymphoblastic leukemia in first remission: a prospective sibling donor versus no-donor comparison
Supplemental data

VASCULAR BIOLOGY

Urokinase mediates endothelial cell survival via induction of the X-linked inhibitor of apoptosis protein
Gerald W. Prager,Judit Mihaly,Patrick M. Brunner,Yuri Koshelnick,Gunilla Hoyer-Hansen,Bernd R. Binder
View Articletitled, Urokinase mediates endothelial cell survival via induction of the X-linked inhibitor of apoptosis protein

CORRESPONDENCE

Biclonal expansion and heterogeneous lineage involvement in a case of chronic myeloproliferative disease with concurrent MPLW515L/JAK2V617F mutation
Kais Hussein,Oliver Bock,Katharina Theophile,Jerome Schlue,Matthias Ballmaier,Nicolaus Kröger,Gudrun Göhring,Guntram Büsche,Hans Kreipe
View Articletitled, Biclonal expansion and heterogeneous lineage involvement in a case of chronic myeloproliferative disease with concurrent MPL<sup>W515L</sup>/JAK2<sup>V617F</sup> mutation
Supplemental data

ERRATUM

Wang et al. Regulatory polymorphism in vitamin K epoxide reductase complex subunit 1 (VKORC1) affects gene expression and warfarin dose requirement. Blood. 2008;112:1013-10211013–1021
View Articletitled, Wang et al. Regulatory polymorphism in vitamin K epoxide reductase complex subunit 1 (<em>VKORC1</em>) affects gene expression and warfarin dose requirement. Blood. 2008;112:1013-1021<span class="related-article">1013–1021</span>
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