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Journal Articles

ALVR106, an Off-the-Shelf, Multivirus-Specific T-Cell Therapy, for the Treatment of Respiratory Viral Infections: Results from a Phase 1, First-in-Human, Dose-Ranging Trial

Sarah Nikiforow, Mitchell Horwitz, John M. McCarty, Anum Abbas, James M. Coghill, Jenny Stanton, Julie Ma, Spyridoula Vasileiou, Sarah Gilmore, Bhagirathbhai Dholaria, Rabi Hanna, Randy Taplitz, Rajat Bansal

Blood (2023) 142 (Supplement 1): 6889.

https://doi.org/10.1182/blood-2023-189708

Published: 2023

Journal Articles

Abrogation of Immune Effector Cell Neurotoxicity Syndrome (ICANS) By Rimiducid (RIM) in Patients Treated with CD19-Specific Chimeric Antigen Receptor Modified T-Cells (CAR-T) Engineered with an Inducible Caspase 9 (iC9 CAR.19)-Clinical and Pharmacodynamic Correlates

Matthew C. Foster, Barbara Savoldo, Winnie Lau, Clio Rubinos, Natalie S. Grover, Paul M. Armistead, James M. Coghill, Jr., Katarzyna Joanna Jamieson, Robert Hagan, J. Kaitlin Morrison, Faith Brianne Buchanan, Catherine Joyce Arago Cheng, Anastasia Ivanova, Tammy Cavallo, John West, Megan Gonzalez, Jonathan S. Serody, Gianpietro Dotti

Blood (2022) 140 (Supplement 1): 7437–7438.

https://doi.org/10.1182/blood-2022-165558

Published: 2022

Journal Articles

Third Party Type 2 Innate Lymphoid Cells Treat and Prevent GI Tract Acute GvHD

Danny W. Bruce, PhD, Oleg Kolupaev, PhD, Hemamalini Bommiasamy, PhD, Heather Stefanski, MD PhD, Bruce R. Blazar, MD, James M. Coghill, Jr., MD, Jonathan S Serody, MD

Blood (2019) 134 (Supplement_1): 3205.

https://doi.org/10.1182/blood-2019-126848

Published: 2019

Journal Articles

A Critical Role for Donor-Derived IL-22 in Cutaneous Chronic Gvhd

Blood (2017) 130 (Supplement 1): 69.

https://doi.org/10.1182/blood.V130.Suppl_1.69.69

Published: 2017

Journal Articles

A Novel Process for the Expansion of Functional Human ILC2 Cells for GCHD Prevention

Yan Xing, MDPhD, Heather Stefanski, MD PhD, Danny W. Bruce, PhD, Keli Lee Hippen, PhD, James M. Coghill, Jr., MD, Karen McKinnon, PhD, Shannon Reisdorf, BS, Bruce Blazar, MD, Jonathan S Serody, MD

Blood (2017) 130 (Supplement 1): 4432.

https://doi.org/10.1182/blood.V130.Suppl_1.4432.4432

Published: 2017

Journal Articles

The Anti-Viral Compound Cosalane Attenuates Acute Graft-Versus-Host Disease in Murine Hematopoietic Stem Cell Transplant Models

Kenneth A. Fowler, MS, Danny W. Bruce, PhD, James M. Coghill, Jr., MD

Blood (2017) 130 (Supplement 1): 3178.

https://doi.org/10.1182/blood.V130.Suppl_1.3178.3178

Published: 2017

Journal Articles

T-cell expression of AhR inhibits the maintenance of pT reg cells in the gastrointestinal tract in acute GVHD

Trisha A. Dant, Kaifeng L. Lin, Danny W. Bruce, Stephanie A. Montgomery, Oleg V. Kolupaev, Hemamalini Bommiasamy, Lisa M. Bixby, John T. Woosley, Karen P. McKinnon, Frank J. Gonzalez, Bruce R. Blazar, Benjamin G. Vincent, James M. Coghill, Jonathan S. Serody

Blood (2017) 130 (3): 348–359.

https://doi.org/10.1182/blood-2016-08-734244

Published: 2017

Includes: Supplemental data

Journal Articles

Infusion of Ex Vivo Activated Donor Type 2 Innate Lymphoid Cells Inhibit Th1 Activity and Reduces Acute Graft-Versus-Host Disease

Danny Bruce, PhD, Michelle West, BS, Trisha A Dant, BS, Angela Panoskaltsis-Mortari, PhD, Bruce R. Blazar, MD, James M Coghill, MD, Jonathan S Serody, MD

Blood (2014) 124 (21): 538.

https://doi.org/10.1182/blood.V124.21.538.538

Published: 2014

Journal Articles

Plasticity of Th17 Cells and Conversion to Th1 Cells during Acute GvHD

Hemamalini Bommiasamy, PhD, Michelle West, BS, Brigitta Stockinger, PhD, James M Coghill, MD, Jonathan S Serody, MD

Blood (2014) 124 (21): 3821.

https://doi.org/10.1182/blood.V124.21.3821.3821

Published: 2014

Journal Articles

Intravital imaging of donor allogeneic effector and regulatory T cells with host dendritic cells during GVHD

Kaifeng Lisa Lin, LeShara M. Fulton, Matthew Berginski, Michelle L. West, Nicholas A. Taylor, Timothy P. Moran, James M. Coghill, Bruce R. Blazar, James E. Bear, Jonathan S. Serody

Blood (2014) 123 (10): 1604–1614.

https://doi.org/10.1182/blood-2013-09-526020

Published: 2014

Includes: Multimedia, Supplemental data

Journal Articles

CC chemokine receptor 8 potentiates donor T reg survival and is critical for the prevention of murine graft-versus-host disease

James M. Coghill, Kenneth A. Fowler, Michelle L. West, LeShara M. Fulton, Hendrik van Deventer, Karen P. McKinnon, Benjamin G. Vincent, Kaifeng Lin, Angela Panoskaltsis-Mortari, Donald N. Cook, Bruce R. Blazar, Jonathan S. Serody

Blood (2013) 122 (5): 825–836.

https://doi.org/10.1182/blood-2012-06-435735

Published: 2013

Includes: Supplemental data

Journal Articles

Effector CD4 + T cells, the cytokines they generate, and GVHD: something old and something new

James M. Coghill, Stefanie Sarantopoulos, Timothy P. Moran, William J. Murphy, Bruce R. Blazar, Jonathan S. Serody

Blood (2011) 117 (12): 3268–3276.

https://doi.org/10.1182/blood-2010-12-290403

Published: 2011

Journal Articles

The Absence of CC-Chemokine Receptor 8 on Donor Regulatory T Cells Impairs Their Ability to Prevent Lethal Acute Gvhd.

James M. Coghill, MD, Michelle L. West, BS, Donald N. Cook, PhD, Jonathan S. Serody, MD, PhD

Blood (2010) 116 (21): 3743.

https://doi.org/10.1182/blood.V116.21.3743.3743

Published: 2010

Journal Articles

Separation of graft-versus-host disease from graft-versus-leukemia responses by targeting CC-chemokine receptor 7 on donor T cells

James M. Coghill, Michael J. Carlson, Angela Panoskaltsis-Mortari, Michelle L. West, Joseph E. Burgents, Bruce R. Blazar, Jonathan S. Serody

Blood (2010) 115 (23): 4914–4922.

https://doi.org/10.1182/blood-2009-08-239848

Published: 2010

Includes: Supplemental data

Journal Articles

The Efficacy and Safety of VP-16 and G-CSF as a Mobilization Regimen Prior to Autologous Stem Cell Transplantation (ASCT) for Patients (Pts) with Multiple Myeloma (MM) and Lymphoma.

William A. Wood, MD, MPH, Julia Whitley, Dominic T Moore, PhD, Jonathan S Serody, MD, Don A. Gabriel, MD, PhD, James M. Coghill, MD, Robert Irons, PA-C, Thomas C. Shea, MD

Blood (2009) 114 (22): 4225.

https://doi.org/10.1182/blood.V114.22.4225.4225

Published: 2009

Journal Articles

CCR1 Is Required for Treg-Mediated Protection From Lethal Acute Graft-Versus-Host Disease.

Michael J Carlson, PhD, James M. Coghill, MD, Michelle L. West, B.S., Angela Panoskaltsis-Mortari, PhD, Bruce R. Blazar, MD, Jonathan S Serody, MD

Blood (2009) 114 (22): 1337.

https://doi.org/10.1182/blood.V114.22.1337.1337

Published: 2009

Journal Articles

In vitro–differentiated TH17 cells mediate lethal acute graft-versus-host disease with severe cutaneous and pulmonary pathologic manifestations

Michael J. Carlson, Michelle L. West, James M. Coghill, Angela Panoskaltsis-Mortari, Bruce R. Blazar, Jonathan S. Serody

Blood (2009) 113 (6): 1365–1374.

https://doi.org/10.1182/blood-2008-06-162420

Published: 2009

Includes: Supplemental data

Journal Articles

The Absence of CCR7 on Donor T Cells Leads to Attenuated Graft-Versus- Host Disease (GVHD) with a Preserved Graft-Versus-Leukemia (GVL) Effect

James M. Coghill, MD, Karen N. Hogan, BS, Jonathan S. Serody, MD, PhD

Blood (2008) 112 (11): 810.

https://doi.org/10.1182/blood.V112.11.810.810

Published: 2008

Journal Articles

Adhesion Molecule Blockade with the Humanized Anti-LFA-1 Monoclonal Antibody Efalizumab Improves Steroid Refractory Acute and Chronic Graft-Versus-Host Disease of the Skin

James M. Coghill, MD, Kristine E. Nograles, MD, James G. Krueger, MD, PhD, Amy S. Coghill, RN, MSN, Jonathan S. Serody, MD, PhD, Anastasia Ivanova, PhD, Julia Whitley, BS, Donald Gabriel, MD, PhD, Terrance Comeau, MD, Thomas Shea, MD

Blood (2008) 112 (11): 4350.

https://doi.org/10.1182/blood.V112.11.4350.4350

Published: 2008

Journal Articles

Absence of CCR4 Enhances the Function of Expanded Regulatory T-Cells.

James M. Coghill, MD, Hans Seidel, BS, Jonathan S. Serody, MD, PhD

Blood (2007) 110 (11): 2172.

https://doi.org/10.1182/blood.V110.11.2172.2172

Published: 2007

NARROW

ALVR106, an Off-the-Shelf, Multivirus-Specific T-Cell Therapy, for the Treatment of Respiratory Viral Infections: Results from a Phase 1, First-in-Human, Dose-Ranging Trial

Abrogation of Immune Effector Cell Neurotoxicity Syndrome (ICANS) By Rimiducid (RIM) in Patients Treated with CD19-Specific Chimeric Antigen Receptor Modified T-Cells (CAR-T) Engineered with an Inducible Caspase 9 (iC9 CAR.19)-Clinical and Pharmacodynamic Correlates

Third Party Type 2 Innate Lymphoid Cells Treat and Prevent GI Tract Acute GvHD

A Critical Role for Donor-Derived IL-22 in Cutaneous Chronic Gvhd

A Novel Process for the Expansion of Functional Human ILC2 Cells for GCHD Prevention

The Anti-Viral Compound Cosalane Attenuates Acute Graft-Versus-Host Disease in Murine Hematopoietic Stem Cell Transplant Models

T-cell expression of AhR inhibits the maintenance of pT reg cells in the gastrointestinal tract in acute GVHD

Infusion of Ex Vivo Activated Donor Type 2 Innate Lymphoid Cells Inhibit Th1 Activity and Reduces Acute Graft-Versus-Host Disease

Plasticity of Th17 Cells and Conversion to Th1 Cells during Acute GvHD

Intravital imaging of donor allogeneic effector and regulatory T cells with host dendritic cells during GVHD

CC chemokine receptor 8 potentiates donor T reg survival and is critical for the prevention of murine graft-versus-host disease

Effector CD4 + T cells, the cytokines they generate, and GVHD: something old and something new

The Absence of CC-Chemokine Receptor 8 on Donor Regulatory T Cells Impairs Their Ability to Prevent Lethal Acute Gvhd.

Separation of graft-versus-host disease from graft-versus-leukemia responses by targeting CC-chemokine receptor 7 on donor T cells

The Efficacy and Safety of VP-16 and G-CSF as a Mobilization Regimen Prior to Autologous Stem Cell Transplantation (ASCT) for Patients (Pts) with Multiple Myeloma (MM) and Lymphoma.

CCR1 Is Required for Treg-Mediated Protection From Lethal Acute Graft-Versus-Host Disease.

In vitro–differentiated TH17 cells mediate lethal acute graft-versus-host disease with severe cutaneous and pulmonary pathologic manifestations

The Absence of CCR7 on Donor T Cells Leads to Attenuated Graft-Versus- Host Disease (GVHD) with a Preserved Graft-Versus-Leukemia (GVL) Effect

Adhesion Molecule Blockade with the Humanized Anti-LFA-1 Monoclonal Antibody Efalizumab Improves Steroid Refractory Acute and Chronic Graft-Versus-Host Disease of the Skin

Absence of CCR4 Enhances the Function of Expanded Regulatory T-Cells.

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American Society of Hematology

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American Society of Hematology

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