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Shin-ichiro Takayanagi
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Journal Articles

Dichotomous Regulation of Lysosomes By MYC and Tfeb Controls Hematopoietic Stem Cell Fate

Laura Garcia Prat, PhD BSc, MSc, Kerstin B Kaufmann, PhD, Florin Schneiter, Veronique Voisin, PhD, Alex Murison, Michelle Chan-Seng-Yue, Olga I. Gan, PhD, Jessica L. McLeod, Michelle Shoong, Kristele Pan, Kinam Gupta, Shin-Ichiro Takayanagi, PhD, Elvin Wagenblast, PhD, Weijia Wang, Timm Schroeder, PhD, Stephanie Zhi-Juan Xie, PhD, John E. Dick, PhD FRS
Journal: Blood
Blood (2020) 136 (Supplement 1): 34.
https://doi.org/10.1182/blood-2020-142671
Published: 2020
Journal Articles

Divergent Levels of CD112 and INKA1 Define a Subset of Human Hematopoietic Stem Cells That Resists Regenerative Stress to Preserve Stemness

Kerstin B Kaufmann, PhD, Andy G.X. Zeng, BSc, Etienne Coyaud, Laura Garcia Prat, PhD BSc, MSc, Efthymia Papalexi, BA, Estelle MN Laurent, Michelle Chan-Seng-Yue, Olga I. Gan, PhD, Kristele Pan, Jessica L. McLeod, Sasan Zandi, Shin-Ichiro Takayanagi, PhD, Rahul Satija, Brian Raught, Stephanie Zhi-Juan Xie, PhD, John E. Dick, PhD FRS
Journal: Blood
Blood (2020) 136 (Supplement 1): 5.
https://doi.org/10.1182/blood-2020-137725
Published: 2020
Journal Articles

A stemness screen reveals C3orf54/INKA1 as a promoter of human leukemia stem cell latency

Kerstin B. Kaufmann, Laura Garcia-Prat, Qiang Liu, Stanley W. K. Ng, Shin-Ichiro Takayanagi, Amanda Mitchell, Erno Wienholds, Peter van Galen, Christian A. Cumbaa, Mike J. Tsay, Chiara Pastrello, Elvin Wagenblast, Gabriela Krivdova, Mark D. Minden, Eric R. Lechman, Sasan Zandi, Igor Jurisica, Jean C. Y. Wang, Stephanie Z. Xie, John E. Dick
Journal: Blood
Blood (2019) 133 (20): 2198–2211.
https://doi.org/10.1182/blood-2018-10-881441
Published: 2019
Includes: Supplemental data
Journal Articles

A Stemness Screen Reveals C3ORF54/INKA1 As a Gate-Keeper of Human Stem Cell Latency

Kerstin B. Kaufmann, PhD, Laura Garcia Prat, Shin-Ichiro Takayanagi, PhD, Jessica McLeod, BSc, Olga I. Gan, Kristele Pan, Stephanie Zhi-Juan Xie, PhD, John E. Dick, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 325.
https://doi.org/10.1182/blood-2018-99-115065
Published: 2018
Journal Articles

Chromatin Accessibility Identifies CTCF As a Gatekeeper of Stemness Functions in Human Hematopoietic Development

Naoya Takayama, MD PhD, Alex Murison, PhD, Shin-ichiro Takayanagi, PhD, Sasan Zandi, MD PhD, Nadia Penrod, PhD, Amanda Mitchel, James A. Kennedy, MD PhD, Stanley W.K. Ng, MSc, Stephanie Zhi-Juan Xie, PhD, Mark D. Minden, MD PhD, John E. Dick, PhD, Mathieu Lupien, PhD
Journal: Blood
Blood (2016) 128 (22): 3873.
https://doi.org/10.1182/blood.V128.22.3873.3873
Published: 2016
Journal Articles

First Preclinical Report of the Efficacy and PD Results of KHK2823, a Non-Fucosylated Fully Human Monoclonal Antibody Against IL-3Rα

Tadakazu Akiyama, PhD, Shin-ichiro Takayanagi, PhD, Yoshimi Maekawa, Kohta Miyawaki, MD, Fumiaki Jinnouchi, MD, Takashi Jiromaru, MD, Takeshi Sugio, MD, Shinya Daitoku, MD, Hirotake Kusumoto, MD, Munetake Shimabe, PhD, Satoshi Nishikawa, Kengo Yamawaki, Kousuke Iijima, Masanori Hiura, Takeshi Takahashi, PhD, Yoshikane Kikushige, MD PhD, Hiromi Iwasaki, MD PhD, Koichi Akashi, MD PhD, Tomonori Tawara, PhD
Journal: Blood
Blood (2015) 126 (23): 1349.
https://doi.org/10.1182/blood.V126.23.1349.1349
Published: 2015
Journal Articles

TGF-β as a candidate bone marrow niche signal to induce hematopoietic stem cell hibernation

Satoshi Yamazaki, Atsushi Iwama, Shin-ichiro Takayanagi, Koji Eto, Hideo Ema, Hiromitsu Nakauchi
Journal: Blood
Blood (2009) 113 (6): 1250–1256.
https://doi.org/10.1182/blood-2008-04-146480
Published: 2009
Includes: Supplemental data
Journal Articles

In Vitro Myelo-Lymphoid Colony Formation by Mouse Hematopoietic Stem Cells

Jun Ooehara, Hina Takano, Shin-ichiro Takayanagi, Hiromitsu Nakauchi, Hideo Ema
Journal: Blood
Blood (2008) 112 (11): 3861.
https://doi.org/10.1182/blood.V112.11.3861.3861
Published: 2008
Journal Articles

Interleukin-27 directly induces differentiation in hematopoietic stem cells

Jun Seita, Masayuki Asakawa, Jun Ooehara, Shin-ichiro Takayanagi, Yohei Morita, Nobukazu Watanabe, Koji Fujita, Motoshige Kudo, Junichiro Mizuguchi, Hideo Ema, Hiromitsu Nakauchi, Takayuki Yoshimoto
Journal: Blood
Blood (2008) 111 (4): 1903–1912.
https://doi.org/10.1182/blood-2007-06-093328
Published: 2008
Includes: Supplemental data
Journal Articles

Genetic marking of hematopoietic stem and endothelial cells: identification of the Tmtsp gene encoding a novel cell surface protein with the thrombospondin-1 domain

Shin-ichiro Takayanagi, Takashi Hiroyama, Satoshi Yamazaki, Tomoko Nakajima, Yohei Morita, Joichi Usui, Koji Eto, Tsutomu Motohashi, Kensuke Shiomi, Kazuko Keino-Masu, Masayuki Masu, Yuichi Oike, Shigeo Mori, Nobuaki Yoshida, Atsushi Iwama, Hiromitsu Nakauchi
Journal: Blood
Blood (2006) 107 (11): 4317–4325.
https://doi.org/10.1182/blood-2005-09-3747
Published: 2006
Includes: Supplemental data
Journal Articles

Tmtsp , a Novel Gene Encoding a Cell Surface Protein Highly Specific to Hematopoietic Stem and Endothelial Cells.

Shin-ichiro Takayanagi, Takashi Hiroyama, Satoshi Yamazaki, Atsushi Iwama, Hiromitsu Nakauchi
Journal: Blood
Blood (2004) 104 (11): 3218.
https://doi.org/10.1182/blood.V104.11.3218.3218
Published: 2004