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Volume 6, Issue 12

June 28 2022

In this Issue

CLINICAL GUIDELINES
STIMULUS REPORTS
CLINICAL TRIALS AND OBSERVATIONS
GENE THERAPY
HEMATOPOIESIS AND STEM CELLS
IMMUNOBIOLOGY AND IMMUNOTHERAPY
LYMPHOID NEOPLASIA
MYELOID NEOPLASIA
PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS
PLATELETS AND THROMBOPOIESIS
RED CELLS, IRON, AND ERYTHROPOIESIS
THROMBOSIS AND HEMOSTASIS
RESEARCH LETTERS
ERRATA

CLINICAL GUIDELINES

American Society of Hematology, ABHH, ACHO, Grupo CAHT, Grupo CLAHT, SAH, SBHH, SHU, SOCHIHEM, SOMETH, Sociedad Panameña de Hematología, Sociedad Peruana de Hematología, and SVH 2022 guidelines for prevention of venous thromboembolism in surgical and medical patients and long-distance travelers in Latin America

Ignacio Neumann,Ariel Izcovich,Ricardo Aguilar,Guillermo León Basantes,Patricia Casais,Cecilia C. Colorio,María Cecilia Guillermo Esposito,Pedro P. García Lázaro,Jaime Pereira,Luis A. Meillon-García,Suely Meireles Rezende,Juan Carlos Serrano,Mario L. Tejerina Valle,Felipe Vera,Lorena Karzulovic,Gabriel Rada,Holger J. Schünemann

View Articletitled, American Society of Hematology, ABHH, ACHO, Grupo CAHT, Grupo CLAHT, SAH, SBHH, SHU, SOCHIHEM, SOMETH, Sociedad Panameña de Hematología, Sociedad Peruana de Hematología, and SVH 2022 guidelines for prevention of venous thromboembolism in surgical and medical patients and long-distance travelers in Latin America

Supplemental data

STIMULUS REPORTS

CEACAM1 is a novel culture-compatible surface marker of expanded long-term reconstituting hematopoietic stem cells

Unain Ansari,Elisa Tomellini,Jalila Chagraoui,Bernhard Lehnertz,Nadine Mayotte,Marie-Eve Bordeleau,Philippe P. Roux,Guy Sauvageau

View Articletitled, CEACAM1 is a novel culture-compatible surface marker of expanded long-term reconstituting hematopoietic stem cells

Supplemental data

Physiologically based serum ferritin thresholds for iron deficiency in women of reproductive age who are blood donors

O. Yaw Addo,Zuguo Mei,Eldad A. Hod,Maria Elena Jefferds,Andrea J. Sharma,Rafael C. Flores-Ayala,Steven L. Spitalnik,Gary M. Brittenham

View Articletitled, Physiologically based serum ferritin thresholds for iron deficiency in women of reproductive age who are blood donors

Convalescent plasma with a high level of virus-specific antibody effectively neutralizes SARS-CoV-2 variants of concern

Maggie Li,Evan J. Beck,Oliver Laeyendecker,Yolanda Eby,Aaron A. R. Tobian,Patrizio Caturegli,Camille Wouters,Gregory R. Chiklis,William Block,Robert O. McKie,Michael J. Joyner,Timothy D. Wiltshire,Allan B. Dietz,Thomas J. Gniadek,Arell J. Shapiro,Anusha Yarava,Karen Lane,Daniel F. Hanley,Evan M. Bloch,Shmuel Shoham,Edward R. Cachay,Barry R. Meisenberg,Moises A. Huaman,Yuriko Fukuta,Bela Patel,Sonya L. Heath,Adam C. Levine,James H. Paxton,Shweta Anjan,Jonathan M. Gerber,Kelly A. Gebo,Arturo Casadevall,Andrew Pekosz,David J. Sullivan,and the CSSC group

View Articletitled, Convalescent plasma with a high level of virus-specific antibody effectively neutralizes SARS-CoV-2 variants of concern

Live imaging of platelets and neutrophils during antibody-mediated neurovascular thrombosis

Audree Laroche,Denis Soulet,Marc Bazin,Tania Levesque,Isabelle Allaeys,Nicolas Vallières,Matthias Gunzer,Louis Flamand,Steve Lacroix,Eric Boilard

View Articletitled, Live imaging of platelets and neutrophils during antibody-mediated neurovascular thrombosis

Supplemental data

Defenestrated endothelium delays liver-directed gene transfer in hemophilia A mice

Tomasz W. Kaminski,Eun-Mi Ju,Shweta Gudapati,Ravi Vats,Sanya Arshad,Rikesh K. Dubey,Omika Katoch,Egemen Tutuncuoglu,Jonathan Frank,Tomasz Brzoska,Donna B. Stolz,Simon C. Watkins,Stephen Y. Chan,Margaret V. Ragni,Enrico M. Novelli,Prithu Sundd,Tirthadipa Pradhan-Sundd

View Articletitled, Defenestrated endothelium delays liver-directed gene transfer in hemophilia A mice

Supplemental data

Prevalence of heavy chain MGUS by race and family history risk groups using a high-sensitivity screening method
Clinical Trials & Observations

Celine M. Vachon,Josiah Murray,Cristine Allmer,Dirk Larson,Aaron D. Norman,Jason P. Sinnwell,Angela Dispenzieri,Geffen Kleinstern,Alissa Visram,Robert A. Kyle,S. Vincent Rajkumar,Susan L. Slager,Shaji K. Kumar,David L. Murray

View Articletitled, Prevalence of heavy chain MGUS by race and family history risk groups using a high-sensitivity screening method

Supplemental data

HSCT using carrier donors for CD40L deficiency results in excellent immune function and higher CD40L expression in cTfh

Shanmuganathan Chandrakasan,Sharat Chandra,Chengyu Prince,Lisa J. Kobrynski,Laura Lucas,Kiran Patel,Jolan Walter,Rebecca H. Buckley,Roland Meisel,Sujal Ghosh,Suhag H. Parikh

View Articletitled, HSCT using carrier donors for CD40L deficiency results in excellent immune function and higher CD40L expression in cTfh

Supplemental data

CLINICAL TRIALS AND OBSERVATIONS

Rivaroxaban for the treatment of noncirrhotic splanchnic vein thrombosis: an interventional prospective cohort study
Clinical Trials & Observations

Walter Ageno,Jan Beyer Westendorf,Laura Contino,Eugenio Bucherini,Maria Teresa Sartori,Marco Senzolo,Elvira Grandone,Rita Santoro,Marc Carrier,Aurélien Delluc,Valerio De Stefano,Fulvio Pomero,Marco Paolo Donadini,Alberto Tosetto,Cecilia Becattini,Ida Martinelli,Barbara Nardo,Laurent Bertoletti,Marcello Di Nisio,Alejandro Lazo-Langner,Alessandro Schenone,Nicoletta Riva

View Articletitled, Rivaroxaban for the treatment of noncirrhotic splanchnic vein thrombosis: an interventional prospective cohort study

Supplemental data

Interaction between maternal killer immunoglobulin-like receptors and offspring HLAs and susceptibility of childhood ALL
Clinical Trials & Observations

Qianxi Feng,Mi Zhou,Shaobo Li,Libby Morimoto,Helen Hansen,Swe Swe Myint,Rong Wang,Catherine Metayer,Alice Kang,Anna Lisa Fear,Derek Pappas,Henry Erlich,Jill A. Hollenbach,Nicholas Mancuso,Elizabeth Trachtenberg,Adam J. de Smith,Xiaomei Ma,Joseph L. Wiemels

View Articletitled, Interaction between maternal killer immunoglobulin-like receptors and offspring HLAs and susceptibility of childhood ALL

Supplemental data

Racial and ethnic differences in clonal hematopoiesis, tumor markers, and outcomes of patients with multiple myeloma
Clinical Trials & Observations

Lauren C. Peres,Christelle M. Colin-Leitzinger,Mingxiang Teng,Julie Dutil,Raghunandan R. Alugubelli,Gabriel DeAvila,Jamie K. Teer,Dongliang Du,Qianxing Mo,Erin M. Siegel,Oliver A. Hampton,Melissa Alsina,Jason Brayer,Brandon Blue,Rachid Baz,Ariosto S. Silva,Taiga Nishihori,Kenneth H. Shain,Nancy Gillis

View Articletitled, Racial and ethnic differences in clonal hematopoiesis, tumor markers, and outcomes of patients with multiple myeloma

Supplemental data

Metformin for treatment of cytopenias in children and young adults with Fanconi anemia
Clinical Trials & Observations

Jessica A. Pollard,Elissa Furutani,Shanshan Liu,Erica Esrick,Laurie E. Cohen,Jacob Bledsoe,Chih-Wei Liu,Kun Lu,Maria Jose Ramirez de Haro,Jordi Surrallés,Maggie Malsch,Ashley Kuniholm,Ashley Galvin,Myriam Armant,Annette S. Kim,Kaitlyn Ballotti,Lisa Moreau,Yu Zhou,Daria Babushok,Farid Boulad,Clint Carroll,Helge Hartung,Amy Hont,Taizo Nakano,Tim Olson,Sei-Gyung Sze,Alexis A. Thompson,Marcin W. Wlodarski,Xuesong Gu,Towia A. Libermann,Alan D’Andrea,Markus Grompe,Edie Weller,Akiko Shimamura

View Articletitled, Metformin for treatment of cytopenias in children and young adults with Fanconi anemia

Supplemental data

GENE THERAPY

Transcutaneous ultrasound-mediated gene delivery into canine livers achieves therapeutic levels of factor VIII expression

Megan A. Manson,Feng Zhang,Alexander Novokhodko,Chun-Yu Chen,Maura Parker,Keith R. Loeb,Masaki Kajimoto,Carley Campbell,Rainer F. Storb,Carol H. Miao

View Articletitled, Transcutaneous ultrasound-mediated gene delivery into canine livers achieves therapeutic levels of factor VIII expression

Supplemental data

HEMATOPOIESIS AND STEM CELLS

Cell origin–dependent cooperativity of mutant Dnmt3a and Npm1 in clonal hematopoiesis and myeloid malignancy

Jennifer M. SanMiguel,Elizabeth Eudy,Matthew A. Loberg,Linde A. Miles,Tim Stearns,Jayna J. Mistry,Michael J. Rauh,Ross L. Levine,Jennifer J. Trowbridge

View Articletitled, Cell origin–dependent cooperativity of mutant Dnmt3a and Npm1 in clonal hematopoiesis and myeloid malignancy

Supplemental data

Assessment of systemic and gastrointestinal tissue damage biomarkers for GVHD risk stratification

Aaron Etra,Stephanie Gergoudis,George Morales,Nikolaos Spyrou,Jay Shah,Steven Kowalyk,Francis Ayuk,Janna Baez,Chantiya Chanswangphuwana,Yi-Bin Chen,Hannah Choe,Zachariah DeFilipp,Isha Gandhi,Elizabeth Hexner,William J. Hogan,Ernst Holler,Urvi Kapoor,Carrie L. Kitko,Sabrina Kraus,Jung-Yi Lin,Monzr Al Malki,Pietro Merli,Attaphol Pawarode,Michael A. Pulsipher,Muna Qayed,Ran Reshef,Wolf Rösler,Tal Schechter,Grace Van Hyfte,Daniela Weber,Matthias Wölfl,Rachel Young,Umut Özbek,James L. M. Ferrara,John E. Levine

View Articletitled, Assessment of systemic and gastrointestinal tissue damage biomarkers for GVHD risk stratification

Supplemental data

Functional interaction between compound heterozygous TERT mutations causes severe telomere biology disorder

Aram Niaz,Jia Truong,Annabel Manoleras,Lucy C. Fox,Piers Blombery,Raja S. Vasireddy,Hilda A. Pickett,Julie A. Curtin,Pasquale M. Barbaro,Jonathan Rodgers,John Roy,Lisa G. Riley,Jessica K. Holien,Scott B. Cohen,Tracy M. Bryan

View Articletitled, Functional interaction between compound heterozygous TERT mutations causes severe telomere biology disorder

Supplemental data

IMMUNOBIOLOGY AND IMMUNOTHERAPY

Using stroma-anchoring cytokines to augment ADCC: a phase 1 trial of F16IL2 and BI 836858 for posttransplant AML relapse
Clinical Trials & Observations

Andrew F. Berdel,Leo Ruhnke,Linus Angenendt,Martin Wermke,Christoph Röllig,Jan-Henrik Mikesch,Annika Scheller,Teresa Hemmerle,Mattia Matasci,Klaus Wethmar,Torsten Kessler,Mirjam Gerwing,Daniel Hescheler,Michael Schäfers,Wolfgang Hartmann,Bianca Altvater,Claudia Rossig,Martin Bornhäuser,Georg Lenz,Matthias Stelljes,Bjoern Rueter,Dario Neri,Wolfgang E. Berdel,Christoph Schliemann

View Articletitled, Using stroma-anchoring cytokines to augment ADCC: a phase 1 trial of F16IL2 and BI 836858 for posttransplant AML relapse

Supplemental data

LYMPHOID NEOPLASIA

Prediction of clinical outcome in CLL based on recurrent gene mutations, CLL-IPI variables, and (para)clinical data

Mehdi Parviz,Christian Brieghel,Rudi Agius,Carsten U. Niemann

View Articletitled, Prediction of clinical outcome in CLL based on recurrent gene mutations, CLL-IPI variables, and (para)clinical data

Supplemental data

MYELOID NEOPLASIA

The differential role of the lipid raft-associated protein flotillin 2 for progression of myeloid leukemia

Rahul Kumar,Raquel S. Pereira,Julian Niemann,Alexander I. Azimpour,Costanza Zanetti,Christina Karantanou,Wahyu Minka,Valentina R. Minciacchi,Eric Kowarz,Melanie Meister,Parimala S. Godavarthy,Véronique Maguer-Satta,Sylvain Lefort,Eliza Wiercinska,Halvard Bonig,Rolf Marschalek,Daniela S. Krause

View Articletitled, The differential role of the lipid raft-associated protein flotillin 2 for progression of myeloid leukemia

Supplemental data

Geriatric assessment for older adults receiving less-intensive therapy for acute myeloid leukemia: report of CALGB 361101

Ellen K. Ritchie,Heidi D. Klepin,Elizabeth Storrick,Brittny Major,Jennifer Le-Rademacher,Martha Wadleigh,Alison Walker,Richard A. Larson,Gail J. Roboz

View Articletitled, Geriatric assessment for older adults receiving less-intensive therapy for acute myeloid leukemia: report of CALGB 361101

Supplemental data

PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS

IFNγ regulates NAD⁺ metabolism to promote the respiratory burst in human monocytes

Katelyn J. McCann,Stephen M. Christensen,Devon H. Colby,Peter J. McGuire,Ian A. Myles,Christa S. Zerbe,Clifton L. Dalgard,Gauthaman Sukumar,Warren J. Leonard,Beth A. McCormick,Steven M. Holland

View Articletitled, IFNγ regulates NAD+ metabolism to promote the respiratory burst in human monocytes

Supplemental data

PLATELETS AND THROMBOPOIESIS

Platelet activation by SARS-CoV-2 implicates the release of active tissue factor by infected cells

Florian Puhm,Isabelle Allaeys,Emile Lacasse,Isabelle Dubuc,Yannick Galipeau,Younes Zaid,Loubna Khalki,Clemence Belleannée,Yves Durocher,Alain R. Brisson,Alisa S. Wolberg,Marc-André Langlois,Louis Flamand,Eric Boilard

View Articletitled, Platelet activation by SARS-CoV-2 implicates the release of active tissue factor by infected cells

Supplemental data

Laboratory assays of VWF activity and use of desmopressin trials in the diagnosis of VWD: a systematic review and meta-analysis
Clinical Trials & Observations

Mohamad A. Kalot,Nedaa Husainat,Omar Abughanimeh,Osama Diab,Abdallah El Alayli,Sammy Tayiem,Bader Madoukh,Ahmad Dimassi,Aref Qureini,Barbara Ameer,Jeroen Eikenboom,Nicolas Giraud,Sandra Haberichter,Vicky Jacobs-Pratt,Barbara A. Konkle,Simon McRae,Robert Montgomery,James S. O’Donnell,Romina Brignardello-Petersen,Veronica Flood,Nathan T. Connell,Paula James,Reem A. Mustafa

View Articletitled, Laboratory assays of VWF activity and use of desmopressin trials in the diagnosis of VWD: a systematic review and meta-analysis

Supplemental data

RED CELLS, IRON, AND ERYTHROPOIESIS

ATG4A regulates human erythroid maturation and mitochondrial clearance

Massiel Chavez Stolla,Andreea Reilly,Rochelle Bergantinos,Sintra Stewart,Neele Thom,Courtnee A. Clough,Rachel C. Wellington,Raisa Stolitenko,Janis L. Abkowitz,Sergei Doulatov

View Articletitled, ATG4A regulates human erythroid maturation and mitochondrial clearance

Supplemental data

THROMBOSIS AND HEMOSTASIS

Alterations in B- and circulating T-follicular helper cell subsets in immune thrombotic thrombocytopenic purpura

Jin-Sup Shin,Maryam Owais Subhan,Geraldine Cambridge,Yanping Guo,Rens de Groot,Marie Scully,Mari Thomas

View Articletitled, Alterations in B- and circulating T-follicular helper cell subsets in immune thrombotic thrombocytopenic purpura

Supplemental data

RESEARCH LETTERS

TTMV-RARA fusion as a recurrent cause of AML with APL characteristics
Clinical Trials & Observations

Olga Sala-Torra,Lan W. Beppu,Faduma A. Abukar,Jerald P. Radich,Cecilia C. S. Yeung

View Articletitled, TTMV-RARA fusion as a recurrent cause of AML with APL characteristics

Supplemental data

Real-world evidence of brexucabtagene autoleucel for the treatment of relapsed or refractory mantle cell lymphoma

Gloria Iacoboni,Kai Rejeski,Guillermo Villacampa,Jaap A. van Doesum,Annalisa Chiappella,Francesca Bonifazi,Lucia Lopez-Corral,Michiel van Aalderen,Mi Kwon,Nuria Martínez-Cibrian,Stefania Bramanti,Juan Luis Reguera-Ortega,Lina Camacho-Arteaga,Christian Schmidt,Ana Marín-Niebla,Marie José Kersten,Alejandro Martin Garcia-Sancho,Pier Luigi Zinzani,Paolo Corradini,Tom van Meerten,Marion Subklewe,Pere Barba

View Articletitled, Real-world evidence of brexucabtagene autoleucel for the treatment of relapsed or refractory mantle cell lymphoma

Supplemental data

Prevalence of IGLV3-21^R110 among familial CLL: a retrospective study of 45 cases

Marine Armand,Patricia Verrier,Floriane Theves,Clotilde Bravetti,Magali Le Garff-Tavernier,Sylvain Choquet,Frédéric Davi

View Articletitled, Prevalence of IGLV3-21R110 among familial CLL: a retrospective study of 45 cases

Supplemental data

Simplified detection of Epstein-Barr virus for diagnosis of endemic Burkitt lymphoma

Andrea Gardner,Julio Alvarez,Caitlyn Genovese,Ryan Snodgrass,Varun Kopparthy,David Erickson,Ethel Cesarman

View Articletitled, Simplified detection of Epstein-Barr virus for diagnosis of endemic Burkitt lymphoma

Supplemental data

High frequency of central nervous system involvement in transformed Waldenström macroglobulinemia
Clinical Trials & Observations

Eric Durot,Lukshe Kanagaratnam,Saurabh Zanwar,Elise Toussaint,Efstathios Kastritis,Shirley D’Sa,Miguel Alcoceba,Cécile Tomowiak,Bénédicte Hivert,Caroline Protin,Jithma P. Abeykoon,Josephine M. I. Vos,Anne-Sophie Michallet,Cyrielle Rodier,Jehan Dupuis,Stéphane Leprêtre,Fatiha Merabet,Xavier Roussel,Jean-Marc Zini,Caroline Regny,Aisha Patel,Pierre Morel,Damien Roos-Weil,Steven P. Treon,Meletios A. Dimopoulos,Ramon Garcia-Sanz,Prashant Kapoor,Jorge J. Castillo,Alain Jacques Delmer

View Articletitled, High frequency of central nervous system involvement in transformed Waldenström macroglobulinemia

Supplemental data

Fertility testing knowledge and attitudes in male adolescents and young adults with SCD and their caregivers: a pilot study
Clinical Trials & Observations

Leena Nahata,Charis J. Stanek,Charleen I. Theroux,Anna L. Olsavsky,Gwendolyn P. Quinn,Susan E. Creary

View Articletitled, Fertility testing knowledge and attitudes in male adolescents and young adults with SCD and their caregivers: a pilot study

ERRATA

Lissitchkov T, Willemze A, Katragadda S, et al. Efanesoctocog alfa for hemophilia A: results from a phase 1 repeat-dose study. Blood Adv. 2022;6(4):1089-1094.

View Articletitled, Lissitchkov T, Willemze A, Katragadda S, et al. Efanesoctocog alfa for hemophilia A: results from a phase 1 repeat-dose study. Blood Adv. 2022;6(4):1089-1094.

Koh J, Jang I, Mun S, et al. Genetic profiles of subcutaneous panniculitis-like T-cell lymphoma and clinicopathological impact of HAVCR2 mutations. Blood Adv. 2021;5(20):3919-3930.

View Articletitled, Koh J, Jang I, Mun S, et al. Genetic profiles of subcutaneous panniculitis-like T-cell lymphoma and clinicopathological impact of HAVCR2 mutations. Blood Adv. 2021;5(20):3919-3930.

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Immunofluorescence studies on 3T3 fibroblasts transduced with MLL-AF9-expressing retrovirus and Flot2 shRNA-expressing lentivirus, grown on coverslips and stained with phalloidin and DAPI. See the article by Kumar et al.
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Subsequent malignant neoplasms in patients previously treated with anti-CD19 CAR T-cell therapy

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A multicenter study of venetoclax-based treatment for patients with Richter transformation of chronic lymphocytic leukemia

Race and ethnicity reporting and representation in hemophilia clinical trials

Issue Archive

Table of Contents

CLINICAL GUIDELINES

STIMULUS REPORTS

Prevalence of heavy chain MGUS by race and family history risk groups using a high-sensitivity screening method Clinical Trials & Observations

CLINICAL TRIALS AND OBSERVATIONS

Rivaroxaban for the treatment of noncirrhotic splanchnic vein thrombosis: an interventional prospective cohort study Clinical Trials & Observations

Interaction between maternal killer immunoglobulin-like receptors and offspring HLAs and susceptibility of childhood ALL Clinical Trials & Observations

Racial and ethnic differences in clonal hematopoiesis, tumor markers, and outcomes of patients with multiple myeloma Clinical Trials & Observations

Metformin for treatment of cytopenias in children and young adults with Fanconi anemia Clinical Trials & Observations

GENE THERAPY

HEMATOPOIESIS AND STEM CELLS

IMMUNOBIOLOGY AND IMMUNOTHERAPY

Using stroma-anchoring cytokines to augment ADCC: a phase 1 trial of F16IL2 and BI 836858 for posttransplant AML relapse Clinical Trials & Observations

LYMPHOID NEOPLASIA

MYELOID NEOPLASIA

PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS

PLATELETS AND THROMBOPOIESIS

Laboratory assays of VWF activity and use of desmopressin trials in the diagnosis of VWD: a systematic review and meta-analysis Clinical Trials & Observations

RED CELLS, IRON, AND ERYTHROPOIESIS

THROMBOSIS AND HEMOSTASIS

RESEARCH LETTERS

TTMV-RARA fusion as a recurrent cause of AML with APL characteristics Clinical Trials & Observations

High frequency of central nervous system involvement in transformed Waldenström macroglobulinemia Clinical Trials & Observations

Fertility testing knowledge and attitudes in male adolescents and young adults with SCD and their caregivers: a pilot study Clinical Trials & Observations

ERRATA

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American Society of Hematology

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Prevalence of heavy chain MGUS by race and family history risk groups using a high-sensitivity screening method
Clinical Trials & Observations

Rivaroxaban for the treatment of noncirrhotic splanchnic vein thrombosis: an interventional prospective cohort study
Clinical Trials & Observations

Interaction between maternal killer immunoglobulin-like receptors and offspring HLAs and susceptibility of childhood ALL
Clinical Trials & Observations

Racial and ethnic differences in clonal hematopoiesis, tumor markers, and outcomes of patients with multiple myeloma
Clinical Trials & Observations

Metformin for treatment of cytopenias in children and young adults with Fanconi anemia
Clinical Trials & Observations

Using stroma-anchoring cytokines to augment ADCC: a phase 1 trial of F16IL2 and BI 836858 for posttransplant AML relapse
Clinical Trials & Observations

Laboratory assays of VWF activity and use of desmopressin trials in the diagnosis of VWD: a systematic review and meta-analysis
Clinical Trials & Observations

TTMV-RARA fusion as a recurrent cause of AML with APL characteristics
Clinical Trials & Observations

High frequency of central nervous system involvement in transformed Waldenström macroglobulinemia
Clinical Trials & Observations

Fertility testing knowledge and attitudes in male adolescents and young adults with SCD and their caregivers: a pilot study
Clinical Trials & Observations