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Ernst Holler
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Journal Articles

The MAGIC algorithm probability predicts treatment response and long-term outcomes to second-line therapy for acute GVHD

Zachariah DeFilipp, Haesook T. Kim, Nikolaos Spyrou, Nikolaos Katsivelos, Steven Kowalyk, Gilbert Eng, Stelios Kasikis, Rahnuma Beheshti, Janna Baez, Yu Akahoshi, Francis Ayuk, Hannah Choe, Aaron Etra, Stephan A. Grupp, Elizabeth O. Hexner, William J. Hogan, Carrie L. Kitko, Muna Qayed, Ran Reshef, Ingrid Vasova, Robert Zeiser, Rachel Young, Ernst Holler, James L. M. Ferrara, Ryotaro Nakamura, John E. Levine, Yi-Bin Chen
Journal: Blood Advances
Blood Adv (2024) 8 (13): 3488–3496.
https://doi.org/10.1182/bloodadvances.2024012561
Published: 2024
Includes: Supplemental data
Journal Articles

Amphiregulin, ST2, and REG3α biomarker risk algorithms as predictors of nonrelapse mortality in patients with acute GVHD

Aaron Etra, Najla El Jurdi, Nikolaos Katsivelos, Deukwoo Kwon, Stephanie Gergoudis, George Morales, Nikolaos Spyrou, Steven Kowalyk, Paibel Aguayo-Hiraldo, Yu Akahoshi, Francis Ayuk, Janna Baez, Brian C. Betts, Chantiya Chanswangphuwana, Yi-Bin Chen, Hannah Choe, Zachariah DeFilipp, Sigrun Gleich, Elizabeth Hexner, William J. Hogan, Ernst Holler, Carrie L. Kitko, Sabrina Kraus, Monzr Al Malki, Margaret MacMillan, Attaphol Pawarode, Francesco Quagliarella, Muna Qayed, Ran Reshef, Tal Schechter, Ingrid Vasova, Daniel Weisdorf, Matthias Wölfl, Rachel Young, Ryotaro Nakamura, James L. M. Ferrara, John E. Levine, Shernan Holtan
Journal: Blood Advances
Blood Adv (2024) 8 (12): 3284–3292.
https://doi.org/10.1182/bloodadvances.2023011049
Published: 2024
Includes: Supplemental data
Journal Articles

Phase 2 study of natalizumab plus standard corticosteroid treatment for high-risk acute graft-versus-host disease

Clinical Trials & Observations
Monzr M. Al Malki, Kaitlyn London, Janna Baez, Yu Akahoshi, William J. Hogan, Aaron Etra, Hannah Choe, Elizabeth Hexner, Amelia Langston, Sunil Abhyankar, Doris M. Ponce, Zachariah DeFilipp, Carrie L. Kitko, Kehinde Adekola, Ran Reshef, Francis Ayuk, Alexandra Capellini, Chantiya Chanswangphuwana, Matthias Eder, Gilbert Eng, Isha Gandhi, Stephan Grupp, Sigrun Gleich, Ernst Holler, Nora Rebeka Javorniczky, Stelios Kasikis, Steven Kowalyk, George Morales, Umut Özbek, Wolf Rösler, Nikolaos Spyrou, Gregory Yanik, Rachel Young, Yi-Bin Chen, Ryotaro Nakamura, James L. M. Ferrara, John E. Levine
Journal: Blood Advances
Blood Adv (2023) 7 (17): 5189–5198.
https://doi.org/10.1182/bloodadvances.2023009853
Published: 2023
Includes: Supplemental data
Journal Articles

The utility of biomarkers in acute GVHD prognostication

Clinical Trials & Observations
Nikolaos Spyrou, Yu Akahoshi, Francis Ayuk, Ernst Holler, Hannah Choe, Aaron Etra, William J. Hogan, Wolf Rösler, Elizabeth Hexner, Zachariah DeFilipp, Ran Reshef, Chantiya Chanswangphuwana, Muna Qayed, Sabrina Kraus, Matthias Eder, Nora Rebeka Javorniczky, Stephan A. Grupp, Carrie L. Kitko, Pietro Merli, Paibel Aguayo-Hiraldo, Matthias Wölfl, Janna Baez, Rahnuma Beheshti, Gilbert Eng, Sigrun Gleich, Nikolaos Katsivelos, Alina Khan, Steven Kowalyk, George Morales, Rachel Young, Ryotaro Nakamura, Yi-Bin Chen, John E. Levine, James L. M. Ferrara
Journal: Blood Advances
Blood Adv (2023) 7 (17): 5152–5155.
https://doi.org/10.1182/bloodadvances.2023009929
Published: 2023
Includes: Supplemental data
Journal Articles

Reg3α concentrations at day of allogeneic stem cell transplantation predict outcome and correlate with early antibiotic use

Daniela Weber, Markus Weber, Elisabeth Meedt, Sakhila Ghimire, Daniel Wolff, Matthias Edinger, Hendrik Poeck, Andreas Hiergeist, André Gessner, Francis Ayuk, Wolf Roesler, Matthias Wölfl, Sabrina Kraus, Robert Zeiser, Hannah Bertrand, Peter Bader, Evelyn Ullrich, Matthias Eder, Sigrun Gleich, Rachel Young, Wolfgang Herr, John E. Levine, James L. M. Ferrara, Ernst Holler
Journal: Blood Advances
Blood Adv (2023) 7 (7): 1326–1335.
https://doi.org/10.1182/bloodadvances.2022008480
Published: 2023
Includes: Supplemental data
Journal Articles

Assessment of systemic and gastrointestinal tissue damage biomarkers for GVHD risk stratification

Aaron Etra, Stephanie Gergoudis, George Morales, Nikolaos Spyrou, Jay Shah, Steven Kowalyk, Francis Ayuk, Janna Baez, Chantiya Chanswangphuwana, Yi-Bin Chen, Hannah Choe, Zachariah DeFilipp, Isha Gandhi, Elizabeth Hexner, William J. Hogan, Ernst Holler, Urvi Kapoor, Carrie L. Kitko, Sabrina Kraus, Jung-Yi Lin, Monzr Al Malki, Pietro Merli, Attaphol Pawarode, Michael A. Pulsipher, Muna Qayed, Ran Reshef, Wolf Rösler, Tal Schechter, Grace Van Hyfte, Daniela Weber, Matthias Wölfl, Rachel Young, Umut Özbek, James L. M. Ferrara, John E. Levine
Journal: Blood Advances
Blood Adv (2022) 6 (12): 3707–3715.
https://doi.org/10.1182/bloodadvances.2022007296
Published: 2022
Includes: Supplemental data
Journal Articles

Biomarker-guided preemption of steroid-refractory graft-versus-host disease with α-1-antitrypsin

Clinical Trials & Observations
Stephanie C. Gergoudis, Zachariah DeFilipp, Umut Özbek, Karamjeet S. Sandhu, Aaron M. Etra, Hannah K. Choe, Carrie L. Kitko, Francis Ayuk, Mina Aziz, Janna Baez, Kaitlyn Ben-David, Udomsak Bunworasate, Isha Gandhi, Elizabeth O. Hexner, William J. Hogan, Ernst Holler, Stelios Kasikis, Steven M. Kowalyk, Jung-Yi Lin, Pietro Merli, George Morales, Ryotaro Nakamura, Ran Reshef, Wolf Rösler, Hrishikesh Srinagesh, Rachel Young, Yi-Bin Chen, James L. M. Ferrara, John E. Levine
Journal: Blood Advances
Blood Adv (2020) 4 (24): 6098–6105.
https://doi.org/10.1182/bloodadvances.2020003336
Published: 2020
Includes: Supplemental data
Journal Articles

Amphiregulin modifies the Minnesota Acute Graft-versus-Host Disease Risk Score: results from BMT CTN 0302/0802

Clinical Trials & Observations
Shernan G. Holtan, Todd E. DeFor, Angela Panoskaltsis-Mortari, Nandita Khera, John E. Levine, Mary E. D. Flowers, Stephanie J. Lee, Yoshihiro Inamoto, George L. Chen, Sebastian Mayer, Mukta Arora, Jeanne Palmer, Corey S. Cutler, Sally Arai, Aleksandr Lazaryan, Laura F. Newell, Madan H. Jagasia, Iskra Pusic, William A. Wood, Anne S. Renteria, Gregory Yanik, William J. Hogan, Elizabeth Hexner, Francis Ayuk, Ernst Holler, Udomsak Bunworasate, Yvonne A. Efebera, James L. M. Ferrara, Joseph Pidala, Alan Howard, Juan Wu, Javier Bolaños-Meade, Vincent Ho, Amin Alousi, Bruce R. Blazar, Daniel J. Weisdorf, Margaret L. MacMillan
Journal: Blood Advances
Blood Adv (2018) 2 (15): 1882–1888.
https://doi.org/10.1182/bloodadvances.2018017343
Published: 2018
Includes: Supplemental data
Journal Articles

Third-party fecal microbiota transplantation following allo-HCT reconstitutes microbiome diversity

Clinical Trials & Observations
Zachariah DeFilipp, Jonathan U. Peled, Shuli Li, Jasmin Mahabamunuge, Zeina Dagher, Ann E. Slingerland, Candice Del Rio, Betsy Valles, Maria E. Kempner, Melissa Smith, Jami Brown, Bimalangshu R. Dey, Areej El-Jawahri, Steven L. McAfee, Thomas R. Spitzer, Karen K. Ballen, Anthony D. Sung, Tara E. Dalton, Julia A. Messina, Katja Dettmer, Gerhard Liebisch, Peter Oefner, Ying Taur, Eric G. Pamer, Ernst Holler, Michael K. Mansour, Marcel R. M. van den Brink, Elizabeth Hohmann, Robert R. Jenq, Yi-Bin Chen
Journal: Blood Advances
Blood Adv (2018) 2 (7): 745–753.
https://doi.org/10.1182/bloodadvances.2018017731
Published: 2018
Includes: Supplemental data