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Journal Articles

Secondary Genetic Alterations and Measurable Residual Disease in Core Binding Factor Acute Myeloid Leukemia - a Study from the Acute Leukemia French Intergroup

Loic Vasseur, Matthieu Duchmann, Nicolas Duployez, Emmanuel Raffoux, Celine Berthon, Mael Heiblig, Alexis Genthon, Thorsten Braun, Mathieu Leclerc, Delphine Lebon, Sylvain Chantepie, Jean-Baptiste Micol, Juliette Lambert, Christian Recher, Marie-Lorraine Chrétien, Thomas Cluzeau, Julien Vaidie, Jean-Valère Malfuson, Madalina Uzunov, Arnaud Pigneux, Pierre Peterlin, Sihem Tarfi, Pierre Hirsch, Dominique Penther, Eric Jourdan, Karine Celli-Lebras, Claude Preudhomme, Hervé Dombret, Jérôme Lambert, Nicolas Boissel, Raphael Itzykson
Journal: Blood
Blood (2024) 144 (Supplement 1): 227.
https://doi.org/10.1182/blood-2024-194060
Published: 2024
Journal Articles

Sequential Intensified Conditioning Regimen Allogeneic Transplantation in Younger Adult Patients with Adverse-Risk Acute Myeloid Leukemia: A Multi-Center Prospective Study from the Acute Leukemia French Intergroup on Behalf of the Filo, ALFA, and SFGM-TC Study Groups

Regis Peffault de Latour, Edouard Forcade, Anne Huynh, Mathieu Leclerc, Stéphanie Nguyen Quoc, Patrice Ceballos, Jean-Baptiste Méar, Michael Loschi, Helene Labussiere-vallet, Jean-Henri Bourhis, Bruno Lioure, Ibrahim Yakoub-Agha, Jacques-Olivier Bay, Sylvie François, Claude-Éric Bulabois, Sylvain Chantepie, Marie-Thérèse Rubio, Patrice Chevallier, Anne Lise Mesnard, Delphine Lebon, Jean Valere Malfuson, Jérôme Cornillon, Etienne Daguindau, Pascal Turlure, Natacha Maillard, Alban Villate, Marie Robin, Nicole Raus, Jean-Yves Cahn, Arnaud Pigneux, Mathilde Hunault, Christian Recher, Hervé Dombret, Gerard Socie, Jean François Hamel, Raynier Devillier
Journal: Blood
Blood (2024) 144 (Supplement 1): 3483.
https://doi.org/10.1182/blood-2024-198603
Published: 2024
Journal Articles

Cyclosporine Versus Cyclosporine Plus Mycophenolate Mofetil in Reduced Intensity Allogeneic Stem Cell Transplantation for Intermediate-Risk AML: A Multi-Center Randomized Study from the Acute Leukemia French Intergroup, on Behalf of the Filo, ALFA, and SFGM-TC Study Groups

Edouard Forcade, Raynier Devillier, Jean-François Hamel, Jean-Baptiste Méar, Claude-Éric Bulabois, Jean-Henri Bourhis, Sylvain Chantepie, Pascal Turlure, Patrice Chevallier, Patrice Ceballos, Bruno Lioure, Jacques-Olivier Bay, Jean Valere Malfuson, Stéphanie Nguyen-Quoc, Marianne Schwarz, Jérôme Cornillon, Michael Loschi, Mathieu Leclerc, Marie-Thérèse Rubio, Etienne Daguindau, Natacha Maillard, Amandine Charbonnier, Nathalie Contentin, Hélène Labussière-Wallet, Alban Villate, Ibrahim Yakoub-Agha, Arnaud Pigneux, Mathilde Hunault, Christian Recher, Hervé Dombret, Nicole Raus, Marie Robin, Jean-Yves Cahn, Gerard Socie, Anne Huynh, Régis Peffault De Latour
Journal: Blood
Blood (2024) 144 (Supplement 1): 4909.
https://doi.org/10.1182/blood-2024-203964
Published: 2024
Journal Articles

Long Term Follow-up Data after Consolidation Therapy with Ponatinib in Combination with Cytarabine in Patients with FLT3 Mutated Acute Myeloid Leukemia in First Complete Remission

Thibaut Leguay, Laurène Fenwarth, Thomas Cluzeau, Anne Vekoff, Etienne Lengline, Juliette Lambert, Denis Caillot, Mathilde Hunault, Jean-Valère Malfuson, Sylvain Chantepie, Emmanuelle Tavernier, Berengere Gruson, José Fernandes, Pierre Peterlin, Melody Fort, Laure Morisset, Herve Dombret, Claude Preudhomme, Arnaud Pigneux, Philippe Rousselot
Journal: Blood
Blood (2024) 144 (Supplement 1): 2905.
https://doi.org/10.1182/blood-2024-209998
Published: 2024
Journal Articles

Bortezomib and high-dose melphalan conditioning regimen in frontline multiple myeloma: an IFM randomized phase 3 study

Clinical Trials & Observations
Murielle Roussel, Valérie Lauwers-Cances, Margaret Macro, Xavier Leleu, Bruno Royer, Cyrille Hulin, Lionel Karlin, Aurore Perrot, Cyrille Touzeau, Marie-Lorraine Chrétien, Sophie Rigaudeau, Mamoun Dib, Emmanuelle Nicolas-Virelizier, Martine Escoffre-Barbe, Karim Belhadj, Clara Mariette, Anne-Marie Stoppa, Carla Araujo, Chantal Doyen, Jean Fontan, Brigitte Kolb, Laurent Garderet, Sabine Brechignac, Jean-Valère Malfuson, Arnaud Jaccard, Pascal Lenain, Cécile Borel, Benjamin Hebraud, Omar Benbrahim, Véronique Dorvaux, Salomon Manier, Karine Augeul-Meunier, Marie-Christiane Vekemans, Edouard Randriamalala, Driss Chaoui, Jo Caers, Carine Chaleteix, Lofti Benboubker, Laure Vincent, Sylvie Glaisner, Patricia Zunic, Borhane Slama, Jean-Richard Eveillard, Catherine Humbrecht-Kraut, Véronique Morel, Philippe Mineur, Jean-Claude Eisenmann, Hélène Demarquette, Valentine Richez, Marguerite Vignon, Denis Caillot, Thierry Facon, Philippe Moreau, Anne-Laurène Colin, Pascale Olivier, Soraya Wuilleme, Hervé Avet-Loiseau, Jill Corre, Michel Attal
Journal: Blood
Blood (2022) 139 (18): 2747–2757.
https://doi.org/10.1182/blood.2021014635
Published: 2022
Includes: Supplemental data
Journal Articles

Impact of Central Nervous System Involvement in Adult Patients with Acute Lymphoblastic Leukemia Treated in a Pediatrics-Inspired Protocol - a Graall Study

Corentin Orvain, Sylvain Chantepie, Xavier Thomas, Martine Escoffre-Barbe, Francoise Huguet, Yohan Desbrosses, Gaelle Guillerm, Thibaut Leguay, Sarah Barbieux, Norbert Vey, Patrice Chevallier, Jean Valere Malfuson, Stephane Lepretre, Jean Pierre Marolleau, Hacene Zerazhi, Diana Carp, Ambroise Marçais, Maria Pilar Gallego Hernanz, Iona Vaida, Florence Pasquier, Veronique Lheritier, Norbert Ifrah, Hervé Dombret, Nicolas Boissel, Hunault-Berger Mathilde
Journal: Blood
Blood (2021) 138 (Supplement 1): 215.
https://doi.org/10.1182/blood-2021-150705
Published: 2021
Journal Articles

Retrospective Analysis of the Outcomes of Patients with Relapsed/Refractory Acute Myeloid Leukemia Included in a Patient Named Program of Gemtuzumab Ozogamicin

Juliette Lambert, Pierre Peterlin, Cecile Pautas, Emmanuel Raffoux, Denis Caillot, Ollivier Legrand, Magalie Joris, Anna Berceanu, Jean Valere Malfuson, Sylvain Chantepie, Marc Bernard, Lauris Gastaud, Arnaud Pigneux, Omar Benbrahim, Caroline Bonmati, Hunault-Berger Mathilde, Hervé Dombret, Philippe Rousselot, Sylvie Chevret, Sylvie Castaigne
Journal: Blood
Blood (2021) 138 (Supplement 1): 876.
https://doi.org/10.1182/blood-2021-145184
Published: 2021
Journal Articles

Replacing the Anthracycline By Gemtuzumab Ozogamicin in Older Patients with De Novo Standard-Risk Acute Myeloid Leukemia Treated Intensively - Results of the Randomized ALFA1401-Mylofrance 4 Study

Juliette Lambert, Jérôme Lambert, Emilie Lemasle, Magalie Joris, Sylvain Chantepie, Cecile Pautas, Xavier Thomas, Jean Valere Malfuson, Lauris Gastaud, Denis Caillot, Emmanuelle Tavernier, Pascal Turlure, Diana Carp, Celine Berthon, Olivier Legrand, Ambroise Marçais, Iona Vaida, Sarah Barbieux, Philippe Rousselot, Claude Gardin, Christine Terré, Nicolas Duployez, Claude Preudhomme, Karine Celli-Lebras, Sylvie Castaigne, Herve Dombret
Journal: Blood
Blood (2021) 138 (Supplement 1): 31.
https://doi.org/10.1182/blood-2021-145152
Published: 2021
Journal Articles

Genetic identification of patients with AML older than 60 years achieving long-term survival with intensive chemotherapy

CME Clinical Trials & Observations
Raphael Itzykson, Elise Fournier, Céline Berthon, Christoph Röllig, Thorsten Braun, Alice Marceau-Renaut, Cécile Pautas, Olivier Nibourel, Emilie Lemasle, Jean-Baptiste Micol, Lionel Adès, Delphine Lebon, Jean-Valère Malfuson, Lauris Gastaud, Laure Goursaud, Emmanuel Raffoux, Kevin-James Wattebled, Philippe Rousselot, Xavier Thomas, Sylvain Chantepie, Thomas Cluzeau, Hubert Serve, Nicolas Boissel, Christine Terré, Karine Celli-Lebras, Claude Preudhomme, Christian Thiede, Hervé Dombret, Claude Gardin, Nicolas Duployez
Journal: Blood
Blood (2021) 138 (7): 507–519.
https://doi.org/10.1182/blood.2021011103
Published: 2021
Includes: Supplemental data
Journal Articles

BH3 profiling identifies ruxolitinib as a promising partner for venetoclax to treat T-cell prolymphocytic leukemia

Charles Herbaux, Christoph Kornauth, Stéphanie Poulain, Stephen J. F. Chong, Mary C. Collins, Rebecca Valentin, Liam Hackett, Olivier Tournilhac, François Lemonnier, Jehan Dupuis, Adrien Daniel, Cecile Tomowiak, Kamel Laribi, Loïc Renaud, Damien Roos-Weil, Cedric Rossi, Eric Van Den Neste, Cecile Leyronnas, Fatiha Merabet, Jean Valère Malfuson, Mourad Tiab, Loïc Ysebaert, Samuel Ng, Franck Morschhauser, Philipp B. Staber, Matthew S. Davids
Journal: Blood
Blood (2021) 137 (25): 3495–3506.
https://doi.org/10.1182/blood.2020007303
Published: 2021
Includes: Supplemental data
Journal Articles

Prognostic significance of concurrent gene mutations in intensively treated patients with IDH -mutated AML: an ALFA study

CME Clinical Trials & Observations
Matthieu Duchmann, Jean-Baptiste Micol, Nicolas Duployez, Emmanuel Raffoux, Xavier Thomas, Jean-Pierre Marolleau, Thorsten Braun, Lionel Adès, Sylvain Chantepie, Emilie Lemasle, Céline Berthon, Jean-Valère Malfuson, Cécile Pautas, Juliette Lambert, Nicolas Boissel, Karine Celli-Lebras, Denis Caillot, Pascal Turlure, Norbert Vey, Arnaud Pigneux, Christian Recher, Christine Terré, Claude Gardin, Raphaël Itzykson, Claude Preudhomme, Hervé Dombret, Stéphane de Botton
Journal: Blood
Blood (2021) 137 (20): 2827–2837.
https://doi.org/10.1182/blood.2020010165
Published: 2021
Includes: Supplemental data
Journal Articles

A personalized approach to guide allogeneic stem cell transplantation in younger adults with acute myeloid leukemia

Clinical Trials & Observations
Laurène Fenwarth, Xavier Thomas, Stéphane de Botton, Nicolas Duployez, Jean-Henri Bourhis, Auriane Lesieur, Gael Fortin, Paul-Arthur Meslin, Ibrahim Yakoub-Agha, Pierre Sujobert, Pierre-Yves Dumas, Christian Récher, Delphine Lebon, Céline Berthon, Mauricette Michallet, Arnaud Pigneux, Stéphanie Nguyen, Sylvain Chantepie, Norbert Vey, Emmanuel Raffoux, Karine Celli-Lebras, Claude Gardin, Juliette Lambert, Jean-Valère Malfuson, Denis Caillot, Sébastien Maury, Benoît Ducourneau, Pascal Turlure, Emilie Lemasle, Cécile Pautas, Sylvie Chevret, Christine Terré, Nicolas Boissel, Gérard Socié, Hervé Dombret, Claude Preudhomme, Raphael Itzykson
Journal: Blood
Blood (2021) 137 (4): 524–532.
https://doi.org/10.1182/blood.2020005524
Published: 2021
Includes: Supplemental data
Journal Articles

Mutational profile and benefit of gemtuzumab ozogamicin in acute myeloid leukemia

Clinical Trials & Observations Brief Report
Elise Fournier, Nicolas Duployez, Benoît Ducourneau, Emmanuel Raffoux, Pascal Turlure, Denis Caillot, Xavier Thomas, Alice Marceau-Renaut, Sylvain Chantepie, Jean-Valère Malfuson, Emilie Lemasle, Meyling Cheok, Karine Celli-Lebras, Estelle Guerin, Christine Terré, Juliette Lambert, Cécile Pautas, Hervé Dombret, Sylvie Castaigne, Claude Preudhomme, Nicolas Boissel
Journal: Blood
Blood (2020) 135 (8): 542–546.
https://doi.org/10.1182/blood.2019003471
Published: 2020
Includes: Supplemental data
Journal Articles

Maintenance with Weekly Carfilzomib in Elderly Newly Diagnosed Multiple Myeloma (IFM 2012-03)

Arthur Bobin, Guillemette Fouquet, Alain Duhamel, PU/PH, Salomon Manier, MD PhD, Lionel Karlin, MD, Brigitte Kolb, MD, Mourad Tiab, MD, Carla Araujo, MD, Nathalie Meuleman, PhD MD, Jean Valère Malfuson, MD, Pascal Bourquard, MD, Pascal Lenain, MD, Arnaud Jaccard, MD PhD, Karim Belhadj, MD, Michel Attal, MD PhD, Philippe Moreau, MD, Cyrille Hulin, MD, Xavier Leleu, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3190.
https://doi.org/10.1182/blood-2019-131793
Published: 2019
Journal Articles

CD19 CAR T-Cell Therapy in Patients with Relapse/Refractory DLBCL: Retrospective Analysis of the Eligibility Criteria

Jérôme Paillassa, MD, Roberta Di Blasi, Sylvie Chevret, Sophie Bernard, Michael Darmon, MD PhD, Veronique Meignin, Bénédicte Deau-Fischer, Vincent Camus, Rene-Olivier Casasnovas, MD, Guillaume Cartron, Driss Chaoui, Vincent Delwail, MD, Pierre Feugier, MD PhD, Luc Mathieu Fornecker, MD PhD, Emmanuel Gyan, MD PhD, Corinne Haioun, MD PhD, Frederique Kuhnowski, MD, Jean Valère Malfuson, MD, Jean-Pierre Marolleau, MD PhD, Veronique Morel, Gandhi Damaj, MD PhD, Anne Quinquenel, MD, Sophie Rigaudeau, MD, Celia Salanoubat, Géraldine Salmeron, David Sibon, MD PhD, Elie Azoulay, MD PhD, Maxime Berquier, Catherine Thieblemont, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2887.
https://doi.org/10.1182/blood-2019-129532
Published: 2019
Journal Articles

Acute Myeloid Leukemia and Antifungal Prophylaxis Era: Compliance of AML Centers, Invasive Fungal Infection (IFI) Classification, IFI Incidence and AML Outcomes from ALFA 2007- 02 Study

Mauricette Michallet, MD PhD, Mohamad Sobh, PharmD, Stephane Morisset, BioStat, Alexandre Deloire, CRA, Emmanuel Raffoux, MD, Stephane De Botton, Denis Caillot, MD, Sylvain Chantepie, MD, Stephane Girault, MD, Celine Berthon, MD, Sarah Bertoli, MD PhD, Stephane Lepretre, Thibaut Leguay, MD, Sylvie Castaigne, MD, Jean-Pierre Marolleau, MD PhD, Cecile Pautas, MD, Jean Valère Malfuson, MD, Norbert Vey, MD PhD, Lauris Gastaud, Felipe Suarez, MD PhD, Aline Schmidt, MD, Rémy Gressin, MD, Caroline Bonmati, MD, Karine Celli-Lebras, CRA, Mohamed El-Hamri, CRA, Patricia Ribaud, MD, Herve Dombret, MD PhD, Xavier Thomas, MD PhD, Anne Bergeron
Journal: Blood
Blood (2019) 134 (Supplement_1): 2618.
https://doi.org/10.1182/blood-2019-130642
Published: 2019
Journal Articles

Prospective, Multicentric Phase II Randomized Trial Comparing the Efficacy of Methotrexate or Cyclophosphamide in Large Granular Lymphocytic Leukemia: A French National Study. Report on the Interim Analysis

Thierry Lamy, PhD MD, Cedric Pastoret, MD, Roch Houot, MD PhD, Loic Ysebaert, MD PhD, Mathilde Hunault, MD PhD, Gandhi Damaj, Anne Banos, Olivier Tournilhac, Bachra Choufi, Jean-Pierre Marolleau, MD PhD, Jehan Dupuis, MD, Alain Jacques Delmer, MD PhD, Stephane Lepretre, Emmanuel Gyan, MD PhD, Pierre Feugier, MD PhD, Sophie Rigaudeau, MD, Anne Lazareth, MD, Jean Valère Malfuson, MD, Thierry Fest, Eric Bellissant
Journal: Blood
Blood (2019) 134 (Supplement_1): 1545.
https://doi.org/10.1182/blood-2019-123439
Published: 2019
Journal Articles

Prognostic Significance of Concurrent Gene Mutations in Intensively Treated Patients with IDH1/2 Mutated AML

Matthieu Duchmann, Jean-Baptiste Micol, MD, Nicolas Duployez, PharmD, PhD, Emmanuel Raffoux, MD, Xavier Thomas, MD PhD, Jean-Pierre Marolleau, MD PhD, Thorsten Braun, MD, Lionel Ades, MD PhD, Sylvain Chantepie, MD, Emilie Lemasle, MD, Celine Berthon, MD PhD, Jean Valère Malfuson, MD, Cecile Pautas, MD, Juliette Lambert, MD, Nicolas Boissel, MD PhD, Karine Celli-Lebras, CRA, Denis Caillot, MD, Pascal Turlure, MD, Norbert Vey, MD PhD, Arnaud Pigneux, Christian Recher, MD PhD, Christine Terré, PharmD, PhD, Claude Gardin, Raphael Itzykson, MD PhD, Claude Preudhomme, PharmD, PhD, Herve Dombret, MD PhD, Stephane De Botton
Journal: Blood
Blood (2019) 134 (Supplement_1): 1416.
https://doi.org/10.1182/blood-2019-127082
Published: 2019
Journal Articles

Characterizing the Anti-Apoptotic Dependencies of T-Cell Prolymphocytic Leukemia Identifies HDAC and JAK/STAT Pathway Inhibitors As Promising Combination Partners to Augment Bcl-2 Targeted Killing By Venetoclax

Charles Herbaux, MD MSc, Christoph Kornauth, Stéphanie Poulain, MD PhD, Olivier Tournilhac, Mary C Collins, BA, Rebecca Valentin, MD, Stephen Jun Fei Chong, PhD, Jehan Dupuis, MD, Adrien Daniel, Micha Srour, MD, Cecile Tomowiak, MD, Kamel Laribi, MD, Damien Roos-Weil, Cedric Rossi, MD PhD, Nicolas Vanlangendonck, MSc, Cecile Leyronnas, Fatiha Merabet, MD, Jean Valère Malfuson, MD, Mourad Tiab, Samuel Ng, MD PhD, Franck Morschhauser, MD, Philipp Bernhard Staber, MD PhD, Matthew S. Davids, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 807.
https://doi.org/10.1182/blood-2019-126773
Published: 2019
Journal Articles

Light Chain Escape in Multiple Myeloma

Thomas Dejoie, MD, Guillemette Fouquet, Cyrille Hulin, Murielle Roussel, Benjamin Hebraud, Lionel Karlin, MD, Brigitte Kolb, MD, Carla Araujo, MD, Nathalie Meuleman, PhD MD, Mourad Tiab, MD, Jean Valère Malfuson, MD, Pascal Bourquard, MD, Pascal Lenain, MD, Arnaud Jaccard, MD PhD, Karim Belhadj, Gérard Lepeu, MD, Marie Lorraine Chretien, MD, Denis Caillot, Jean Fontan, MD, Philippe Rodon, MD, Anna Schmitt, Laurent Voillat, MD, Sophie Cereja, MD, Brigitte Pegourie, MD, Frederique Kuhnowski, MD, Sophie Rigaudeau, MD, Olivier Decaux, MD, Catherine Humbrecht-Kraut, MD, Jamilé Frayfer, MD, Laurent Garderet, Damien Roos-Weil, MD, Jean Claude Eisenmann, MD, Veronique Dorvaux, MD, Eric G. Voog, MD, Claire Mathiot, MD, Jean-Paul Fermand, MD, Thierry Facon, Hervé Avet-Loiseau, MD PhD, Jean Luc Harousseau, MD, Philippe Moreau, Michel Attal, MD PhD, Xavier Leleu, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1881.
https://doi.org/10.1182/blood-2018-99-112396
Published: 2018