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Journal Articles

A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction As a Developmental Susceptibility to ETV6-RUNX1

Simon E Richardson, MA, MD PhD MRCP, FRPATH, Charlotta Boiers, MDPhD, Alya Zriwil, PhD, Emma Laycock, Virginia A Turati, DPhil, John Brown, PhD, Jason Wray, PhD, Chela James, PhD, Dapeng Wang, PhD, Javier Herrero, PhD, Ewa Sitnicka, PhD, Stefan Karlsson, MD, Andrew J.H. Smith, PhD, Sten Eirik Jacobsen, MDPhD, Tariq Enver, PhD

Blood (2017) 130 (Supplement 1): 1218.

https://doi.org/10.1182/blood.V130.Suppl_1.1218.1218

Published: 2017

Journal Articles

Unravelling Cell Cycle and Ontogeny Transcriptional Heterogeneity in Hematopoietic Stem Cells through Integrated Single Cell RNA-Seq

Benjamin Povinelli, PhD, Quin Wills, MD PhD, Nikolaos Barkas, PhD, Christopher Booth, Kieran Campbell, Sten Eirik Jacobsen, MDPhD, Christopher Yau, PhD, Adam J Mead, MD PhD

Blood (2017) 130 (Supplement 1): 769.

https://doi.org/10.1182/blood.V130.Suppl_1.769.769

Published: 2017

Journal Articles

Single-Cell Analysis of Clonal Dynamics in Childhood ALL Reveals a Key Role for Transcriptional Intratumor Heterogeneity in Driving Resistance to Chemotherapy

Virginia A Turati, PhD, José Afonso Guerra-Assunção, PhD, John C Ambrose, PhD, John Brown, PhD, Mike Hubank, PhD, Alex Hobbs, PhD, Mark Lynch, PhD, Bernadett Gaal, PhD, Sarah Inglott, Lucia Conde, PhD, Simon Richardson, MD PhD, Javier Herrero, PhD, Sten Eirik Jacobsen, MD PhD, Tariq Enver, PhD

Blood (2016) 128 (22): 606.

https://doi.org/10.1182/blood.V128.22.606.606

Published: 2016

Journal Articles

Progression in Patients with with Low- and Intermediate-1 Risk Del(5q) MDS Is Predicted By a Limited Subset of Mutations

Christian Scharenberg, MD, Petter S. Woll, PhD, Valentina Giai, MD PhD, Andrea Pellagatti, PhD, Leonie Saft, MD PhD, Marios Dimitriou, Martin Jädersten, Monika Jansson, Iyadh Douagi, PhD, Donna S. Neuberg, ScD, Mohsen Karimi, Katarina Le Blanc, MD, PhD, Jacqueline Boultwood, PhD, Sten Eirik Jacobsen, MD PhD, Eva Hellstrom-Lindberg, MD PhD

Blood (2016) 128 (22): 4329.

https://doi.org/10.1182/blood.V128.22.4329.4329

Published: 2016

Journal Articles

Single Cell Whole Transcriptome Analysis Reveals Distinct Molecular Signatures of Therapy-Resistant Chronic Myeloid Leukemia Stem Cells

Alice Giustacchini, Supat Thongjuea, Petter S. Woll, PhD, Paul Sopp, Ana Duenas Perez, Nikolaos Barkas, Christopher Booth, Ruggiero Norfo, Sally-Ann Clark, Lauren Jamieson, Sten Eirik Jacobsen, Adam Mead

Blood (2015) 126 (23): 13.

https://doi.org/10.1182/blood.V126.23.13.13

Published: 2015

Journal Articles

Ezh2 and Runx1 Mutations Targeted to Early Lymphoid Progenitors Collaborate to Promote Early Thymic Progenitor Leukemia

Christopher Booth, Nikolas Barkas, Wen Hao Neo, Elizabeth Soilleux, Hanane Boukarabila, Alice Giustacchini, Thomas Milne, Neil Ashley, Joana Carrelha, Lauren Jamieson, Deborah Atkinson, Tiphaine Bouriez-Jones, Sten Eirik Jacobsen, Adam Mead

Blood (2015) 126 (23): 846.

https://doi.org/10.1182/blood.V126.23.846.846

Published: 2015

Journal Articles

An Integrative Genomics Approach Uncovers the Basis of Resistance to AZA Therapy in MDS and CMML

Blood (2015) 126 (23): 710.

https://doi.org/10.1182/blood.V126.23.710.710

Published: 2015

Journal Articles

In Infant ALL with t(4;11)/ MLL-AF4 Multiple and Phenotypically Distinct CD19+ BM Subsets Initiate Leukemia in NOD/SCID Mice..

Michela Bardini, Lilian Wittmann, Lilia Corral, Luca Lo Nigro, Zhi Ma, Rakesh Singh, Giuseppe Basso, Giulio De Rossi, Mel Greaves, Andrea Biondi, Giovanni Cazzaniga, Sten Eirik Jacobsen

Blood (2009) 114 (22): 1432.

https://doi.org/10.1182/blood.V114.22.1432.1432

Published: 2009

Journal Articles

Maintenance Treatment with 5-Azacitidine for Patients with High Risk Myelodysplastic Syndr–ome (MDS) or Acute Myeloid Leukemia Following MDS (MDS-AML) in Complete Remission (CR) after Induction Chemotherapy

Michael Grövdal, Rasheed Khan, Anni Aggerholm, Petar Antunovic, Jan Astermark, Per Bernell, Lena-Maria Engström, Lars Kjeldsen, Olle Linder, Lars Nilsson, Anna Olsson, Jonas Wallvik, Jon Magnus Tangen, Gunnar Öberg, Sten Eirik Jacobsen, Anna Porwit, Peter Hokland, Eva Hellström-Lindberg

Blood (2008) 112 (11): 223.

https://doi.org/10.1182/blood.V112.11.223.223

Published: 2008

Journal Articles

Leukemogenic FLT3 Mutations Confer Enhanced Proliferation and Survival Properties to Multipotent Progenitor Cells in a Murine Model of Chronic Myelomonocytic Leukemia.

Benjamin H. Lee, Zuzana Tothova, Ross L. Levine, Kristina Anderson, Natalija Buza-Vidas, Dana E. Cullen, Elizabeth P. McDowell, Jennifer Adelsperger, Stefan Frohling, Brian J.P. Huntly, Miloslav Beran, Sten Eirik Jacobsen, D. Gary Gilliland

Blood (2007) 110 (11): 1613.

https://doi.org/10.1182/blood.V110.11.1613.1613

Published: 2007

Journal Articles

Maintenance Treatment with Azacytidine for Patients with High Risk Myelodysplastic Syndromes or Acute Myeloid Leukaemia in Complete Remission after Intensive Chemotherapy.

Michael Grövdal, Rasheed Khan, Anni Aggerholm, Petar Antunovic, Jan Astermark, Per Bernell, Lena-Maria Engström, Lars Kjeldsen, Olle Linder, Lars Nilsson, Anna Olsson, Jonas Wallvik, Jon Magnus Tangen, Gunnar Öberg, Sten Eirik Jacobsen, Peter Hokland, Anna Porwit, Eva Hellström-Lindberg

Blood (2007) 110 (11): 818.

https://doi.org/10.1182/blood.V110.11.818.818

Published: 2007

Journal Articles

Enforced Expression of GATA-2 Confers Quiescence on Human Hematopoietic Stem and Progenitor Cells In Vitro and In Vivo .

Alex J. Tipping, Cristina Pina, Anders Castor, Ann Atzberger, Dengli Hong, Lorenza Lazzari, Gillian May, Sten Eirik Jacobsen, Tariq Enver

Blood (2006) 108 (11): 83.

https://doi.org/10.1182/blood.V108.11.83.83

Published: 2006

Journal Articles

Contribution of α6 integrins to hematopoietic stem and progenitor cell homing to bone marrow and collaboration with α4 integrins

Hong Qian, Karl Tryggvason, Sten Eirik Jacobsen, Marja Ekblom

Blood (2006) 107 (9): 3503–3510.

https://doi.org/10.1182/blood-2005-10-3932

Published: 2006

Journal Articles

Notch Activation Converts B Cells into a T Cell Fate at the Earliest Stages of B Cell Committed Progenitors.

Jalal Taneera, Emma Smith, Mikael Sigvardsson, Emil Hansson, Urban Lindahl, Inga-Lill Martensson, Sten Eirik Jacobsen

Blood (2005) 106 (11): 3151.

https://doi.org/10.1182/blood.V106.11.3151.3151

Published: 2005

Journal Articles

Laminin isoform–specific promotion of adhesion and migration of human bone marrow progenitor cells

Yu-Chen Gu, Jarkko Kortesmaa, Karl Tryggvason, Jenny Persson, Peter Ekblom, Sten-Eirik Jacobsen, Marja Ekblom

Blood (2003) 101 (3): 877–885.

https://doi.org/10.1182/blood-2002-03-0796

Published: 2003

Journal Articles

Lentiviral gene transfer into primary and secondary NOD/SCID repopulating cells

Niels-Bjarne Woods, Cecilia Fahlman, Hanna Mikkola, Isao Hamaguchi, Karin Olsson, Romain Zufferey, Sten Eirik Jacobsen, Didier Trono, Stefan Karlsson

Blood (2000) 96 (12): 3725–3733.

https://doi.org/10.1182/blood.V96.12.3725

Published: 2000

Journal Articles

Interleukin-13 in Combination With CD40 Ligand Potently Inhibits Apoptosis in Human B Lymphocytes: Upregulation of Bcl-xL and Mcl-1

Jon Lømo, Heidi Kiil Blomhoff, Sten Eirik Jacobsen, Stanislaw Krajewski, John C. Reed, Erlend B. Smeland

Blood (1997) 89 (12): 4415–4424.

https://doi.org/10.1182/blood.V89.12.4415

Published: 1997

NARROW

A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction As a Developmental Susceptibility to ETV6-RUNX1

Unravelling Cell Cycle and Ontogeny Transcriptional Heterogeneity in Hematopoietic Stem Cells through Integrated Single Cell RNA-Seq

Single-Cell Analysis of Clonal Dynamics in Childhood ALL Reveals a Key Role for Transcriptional Intratumor Heterogeneity in Driving Resistance to Chemotherapy

Progression in Patients with with Low- and Intermediate-1 Risk Del(5q) MDS Is Predicted By a Limited Subset of Mutations

Single Cell Whole Transcriptome Analysis Reveals Distinct Molecular Signatures of Therapy-Resistant Chronic Myeloid Leukemia Stem Cells

Ezh2 and Runx1 Mutations Targeted to Early Lymphoid Progenitors Collaborate to Promote Early Thymic Progenitor Leukemia

An Integrative Genomics Approach Uncovers the Basis of Resistance to AZA Therapy in MDS and CMML

In Infant ALL with t(4;11)/ MLL-AF4 Multiple and Phenotypically Distinct CD19+ BM Subsets Initiate Leukemia in NOD/SCID Mice..

Maintenance Treatment with 5-Azacitidine for Patients with High Risk Myelodysplastic Syndr–ome (MDS) or Acute Myeloid Leukemia Following MDS (MDS-AML) in Complete Remission (CR) after Induction Chemotherapy

Leukemogenic FLT3 Mutations Confer Enhanced Proliferation and Survival Properties to Multipotent Progenitor Cells in a Murine Model of Chronic Myelomonocytic Leukemia.

Maintenance Treatment with Azacytidine for Patients with High Risk Myelodysplastic Syndromes or Acute Myeloid Leukaemia in Complete Remission after Intensive Chemotherapy.

Enforced Expression of GATA-2 Confers Quiescence on Human Hematopoietic Stem and Progenitor Cells In Vitro and In Vivo .

Contribution of α6 integrins to hematopoietic stem and progenitor cell homing to bone marrow and collaboration with α4 integrins

Notch Activation Converts B Cells into a T Cell Fate at the Earliest Stages of B Cell Committed Progenitors.

Laminin isoform–specific promotion of adhesion and migration of human bone marrow progenitor cells

Lentiviral gene transfer into primary and secondary NOD/SCID repopulating cells

Interleukin-13 in Combination With CD40 Ligand Potently Inhibits Apoptosis in Human B Lymphocytes: Upregulation of Bcl-xL and Mcl-1

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American Society of Hematology

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American Society of Hematology

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