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Journal Articles

Characterization of the bone marrow niche in patients with chronic myeloid leukemia identifies CXCL14 as a new therapeutic option

Blood (2023) 142 (1): 73–89.

https://doi.org/10.1182/blood.2022016896

Published: 2023

Includes: Supplemental data

Journal Articles

Critical role of Lama4 for hematopoiesis regeneration and acute myeloid leukemia progression

Huan Cai, Makoto Kondo, Lakshmi Sandhow, Pingnan Xiao, Anne-Sofie Johansson, Takako Sasaki, Joanna Zawacka-Pankau, Karl Tryggvason, Johanna Ungerstedt, Julian Walfridsson, Marja Ekblom, Hong Qian

Blood (2022) 139 (20): 3040–3057.

https://doi.org/10.1182/blood.2021011510

Published: 2022

Includes: Supplemental data

Journal Articles

Phenotypic and Functional Alterations of Bone Marrow Mesenchymal Stem and Progenitor Cells in Chronic Myeloid Leukemia

Monika Dolinska, Johannis Klang, Pingnan Xiao, MD, Andranik Durgaryan, Lakshmi Sandhow, Anne-Sofie Johansson, Makoto Kondo, Stefan Deneberg, MD, PhD, Johanna Ungerstedt, Associate Professor, Katarina Le Blanc, MD, PhD, Leif Stenke, MD PhD, Marja Ekblom, Ulla Stromberg, MDPhD, Satu Mustjoki, MD PhD, Soren Lehmann, MD PhD, Hong Qian, PhD

Blood (2015) 126 (23): 2398.

https://doi.org/10.1182/blood.V126.23.2398.2398

Published: 2015

Journal Articles

Modulation of Leukotriene Signaling Affecting Cell Growth in Chronic Myeloid Leukemia: A Key Pathway to Cure?

Elham Yektaei, PhD, Anders Nilsson, PhD, Barbro Näsman-Glaser, MSc, Marja Ekblom, MD PhD, Hong Qian, PhD, Olof Rådmark, PhD, Ana Zovko, PhD, Lena Kanter, MD PhD, Jonas Wallvik, MD PhD, Leif Stenke, MD PhD

Blood (2015) 126 (23): 5137.

https://doi.org/10.1182/blood.V126.23.5137.5137

Published: 2015

Journal Articles

Mature, Adaptive-like CD56 DIM NK Cells in Chronic Myeloid Leukemia Patients in Treatment Free Remission

Blood (2015) 126 (23): 343.

https://doi.org/10.1182/blood.V126.23.343.343

Published: 2015

Journal Articles

Bone Marrow Lymphocytic Status during Tyrosine Kinase Inhibitor Therapy and Its Relation to Therapy Response in Chronic Phase Chronic Myeloid Leukemia Patients

Mohamed El Missiry, MD MSc, Shady Adnan, MD MSc, Hanna Rajala, MD PhD, Ahmed Al-Samadi, DDS, PhD, Marja Ekblom, Berit Markevän, MD PhD, Ingbritt Åstrand-Grundström, Maren Wold, Birgitte Ravn Juhl, MD dr.MDsci, Ole Weis Bjerrum, MD DMSc, Inger Haulin, Kimmo Porkka, MD PhD, Ulla Olsson-Strömberg, Henrik Hjorth-Hansen, MD PhD, Satu Mustjoki, MD PhD

Blood (2015) 126 (23): 4027.

https://doi.org/10.1182/blood.V126.23.4027.4027

Published: 2015

Journal Articles

Early Disease Relapse after Tyrosine Kinase Inhibitor Treatment Discontinuation in CML Is Related Both to Low Number and Impaired Function of NK-Cells

Blood (2014) 124 (21): 812.

https://doi.org/10.1182/blood.V124.21.812.812

Published: 2014

Journal Articles

Identification Of Bipotential Lin - CD34 + CD38 - Integrin α2 - Erythrocyte-Megakaryocyte Progenitors In Human Bone Marrow

Wan Man Wong, Mikael Sigvardsson, Hong Qian, Marja Ekblom, MD, PhD

Blood (2013) 122 (21): 2423.

https://doi.org/10.1182/blood.V122.21.2423.2423

Published: 2013

Journal Articles

Primary Lin neg /CD45 neg /CD271 pos /PDGFRα low/Neg Stroma Stem Cells In Adult Human Bone Marrow Show a Distinct Molecular Signature and Potent Hematopoiesis-Supporting Function

Hongzhe Li, Ph.D, Dimitra Zacharaki, MS, Roshanak Ghazanfari, MS, Marja Ekblom, MD, PhD, Simón Méndez-Ferrer, Ph.D., Stefan Scheding, MD

Blood (2013) 122 (21): 3699.

https://doi.org/10.1182/blood.V122.21.3699.3699

Published: 2013

Journal Articles

Disease Relapse After TKI Discontinuation In CML Is Related Both To Low Number and Impaired Function Of NK-Cells:Data From Euro-SKI

Blood (2013) 122 (21): 379.

https://doi.org/10.1182/blood.V122.21.379.379

Published: 2013

Journal Articles

Tyrosine kinase inhibitor usage, treatment outcome, and prognostic scores in CML: report from the population-based Swedish CML registry

Blood (2013) 122 (7): 1284–1292.

https://doi.org/10.1182/blood-2013-04-495598

Published: 2013

Journal Articles

Allogeneic Stem Cell Transplantation for Patients with Chronic Myeloid Leukemia After Prior Treatment with Nilotinib or Dasatinib

Michael Schleuning, MD, Marijke Scholten, Anja van Biezen, Arnon Nagler, M.D., Jane F. Apperley, MD, Mauricette Michallet, MD, Andrew Grigg, MD, Richard T. Silver, MD, Armin Leitner, MD, Alois Gratwohl, MD, Marja Ekblom, MD, PhD, H. Jean Khoury, MD, Theo de Witte, MD, Eduardo Olavarría, MD

Blood (2010) 116 (21): 2348.

https://doi.org/10.1182/blood.V116.21.2348.2348

Published: 2010

Journal Articles

Differential Expression of Alpha2 Integrin In Human Bone Marrow and Cord Blood CD34+CD38- Progenitors and Stem Cells Reconstituting NOD/SCID-IL2Rgamma c null Mice.

Wan Man Wong, Ingbritt Åstrand-Grundström, Hong Qian, Marja Ekblom, MD, PhD

Blood (2010) 116 (21): 2609.

https://doi.org/10.1182/blood.V116.21.2609.2609

Published: 2010

Journal Articles

Mono/oligoclonal T and NK cells are common in chronic myeloid leukemia patients at diagnosis and expand during dasatinib therapy

Anna Kreutzman, Vesa Juvonen, Veli Kairisto, Marja Ekblom, Leif Stenke, Ruth Seggewiss, Kimmo Porkka, Satu Mustjoki

Blood (2010) 116 (5): 772–782.

https://doi.org/10.1182/blood-2009-12-256800

Published: 2010

Journal Articles

Mono/Oligoclonal T and NK Cells Are Common in Philadelphia Chromosome Positive (Ph+) Leukemia Patients at Diagnosis and Expand During Successful Tyrosine Kinase Inhibitor Therapy.

Anna Kreutzman, MSc, Vesa Juvonen, PhD, Veli Kairisto, MD, PhD, Marja Ekblom, MD, PhD, Leif Stenke, MD, PhD, Ruth Seggewiss, MD, Kimmo Porkka, MD, PhD, Satu Mustjoki, MD, PhD

Blood (2009) 114 (22): 856.

https://doi.org/10.1182/blood.V114.22.856.856

Published: 2009

Journal Articles

Large Granular Lymphocyte (LGL) Expansions Comprising Oligoclonal T Cell or NK Cell Populations in Dasatinib Treated Patients Are Associated with HLA-A*0201, CMV Reactivation and Enhanced Anti-Leukemic Control.

Satu Mustjoki, MD, PhD, Anna Kreutzman, MSc, Carolin Dix, David A Price, MRCP, DPhil, Kristin Ladell, MD, Marja Ekblom, MD, PhD, Leif Stenke, MD, PhD, Hermann Einsele, MD, Kimmo Porkka, MD, PhD, Ruth Seggewiss, MD

Blood (2009) 114 (22): 1123.

https://doi.org/10.1182/blood.V114.22.1123.1123

Published: 2009

Journal Articles

Clonal Expansion of T/NK-Cells during Tyrosine Kinase Inhibitor Dasatinib Therapy

Blood (2008) 112 (11): 573.

https://doi.org/10.1182/blood.V112.11.573.573

Published: 2008

Journal Articles

Stabilin-1 and Stabilin-2 Are Expressed in Bone Marrow Sinusoidal Endothelial Cells and Mediate Scavenging and Cell Adhesive Functions

Hong Qian, Sophie Johansson, Peter McCourt, Bård Smedsrød, Marja Ekblom, Staffan Johansson

Blood (2008) 112 (11): 1368.

https://doi.org/10.1182/blood.V112.11.1368.1368

Published: 2008

Journal Articles

Clonal Large Granular Lymphocyte (LGL) Expansion Associated with Dasatinib Therapy.

Satu Mustjoki, MD, PhD, Tuisku Laurinolli, Marja Ekblom, MD, PhD, Auvo Rauhala, MD, PhD, Marjatta Sinisalo, MD, Anders Almqvist, MD, Elli Koivunen, MD, PhD, Tuija Lundan, Msc, Freja Ebeling, MD, PhD, Perttu Koskenvesa, MD, Henrik Hjorth-Hansen, MD, PhD, Petteri Arstila, MD, PhD, Leif Stenke, MD, PhD, Juan Luis Steegmann, MD, PhD, Martin Hoglund, MD, PhD, Bengt Simonsson, MD, PhD, Neil Shah, MD, PhD, Ronald Paquette, MD, PhD, Kimmo Porkka, MD, PhD

Blood (2007) 110 (11): 2938.

https://doi.org/10.1182/blood.V110.11.2938.2938

Published: 2007

Journal Articles

Distinct roles of integrins α6 and α4 in homing of fetal liver hematopoietic stem and progenitor cells

Hong Qian, Elisabeth Georges-Labouesse, Alexander Nyström, Anna Domogatskaya, Karl Tryggvason, Sten Eirik W. Jacobsen, Marja Ekblom

Blood (2007) 110 (7): 2399–2407.

https://doi.org/10.1182/blood-2006-10-051276

Published: 2007

Includes: Supplemental data

NARROW

Characterization of the bone marrow niche in patients with chronic myeloid leukemia identifies CXCL14 as a new therapeutic option

Critical role of Lama4 for hematopoiesis regeneration and acute myeloid leukemia progression

Phenotypic and Functional Alterations of Bone Marrow Mesenchymal Stem and Progenitor Cells in Chronic Myeloid Leukemia

Modulation of Leukotriene Signaling Affecting Cell Growth in Chronic Myeloid Leukemia: A Key Pathway to Cure?

Mature, Adaptive-like CD56 DIM NK Cells in Chronic Myeloid Leukemia Patients in Treatment Free Remission

Bone Marrow Lymphocytic Status during Tyrosine Kinase Inhibitor Therapy and Its Relation to Therapy Response in Chronic Phase Chronic Myeloid Leukemia Patients

Early Disease Relapse after Tyrosine Kinase Inhibitor Treatment Discontinuation in CML Is Related Both to Low Number and Impaired Function of NK-Cells

Identification Of Bipotential Lin - CD34 + CD38 - Integrin α2 - Erythrocyte-Megakaryocyte Progenitors In Human Bone Marrow

Primary Lin neg /CD45 neg /CD271 pos /PDGFRα low/Neg Stroma Stem Cells In Adult Human Bone Marrow Show a Distinct Molecular Signature and Potent Hematopoiesis-Supporting Function

Disease Relapse After TKI Discontinuation In CML Is Related Both To Low Number and Impaired Function Of NK-Cells:Data From Euro-SKI

Tyrosine kinase inhibitor usage, treatment outcome, and prognostic scores in CML: report from the population-based Swedish CML registry

Allogeneic Stem Cell Transplantation for Patients with Chronic Myeloid Leukemia After Prior Treatment with Nilotinib or Dasatinib

Differential Expression of Alpha2 Integrin In Human Bone Marrow and Cord Blood CD34+CD38- Progenitors and Stem Cells Reconstituting NOD/SCID-IL2Rgamma c null Mice.

Mono/oligoclonal T and NK cells are common in chronic myeloid leukemia patients at diagnosis and expand during dasatinib therapy

Mono/Oligoclonal T and NK Cells Are Common in Philadelphia Chromosome Positive (Ph+) Leukemia Patients at Diagnosis and Expand During Successful Tyrosine Kinase Inhibitor Therapy.

Large Granular Lymphocyte (LGL) Expansions Comprising Oligoclonal T Cell or NK Cell Populations in Dasatinib Treated Patients Are Associated with HLA-A*0201, CMV Reactivation and Enhanced Anti-Leukemic Control.

Clonal Expansion of T/NK-Cells during Tyrosine Kinase Inhibitor Dasatinib Therapy

Stabilin-1 and Stabilin-2 Are Expressed in Bone Marrow Sinusoidal Endothelial Cells and Mediate Scavenging and Cell Adhesive Functions

Clonal Large Granular Lymphocyte (LGL) Expansion Associated with Dasatinib Therapy.

Distinct roles of integrins α6 and α4 in homing of fetal liver hematopoietic stem and progenitor cells

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American Society of Hematology

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American Society of Hematology

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