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Journal Articles

Acute resistance to BET inhibitors remodels compensatory transcriptional programs via p300 coactivation

Blood blood.2022019306.

https://doi.org/10.1182/blood.2022019306

Published: 2024

Includes: Supplemental data

Journal Articles

Delayed Trp53 Activation Protects Dnmt3a -Mutant Haematopoietic Stem Cells from Inflammatory Attrition

Ludovica Marando, George Giotopoulos, Pedro Madrigal, Dhoyazan M A Azazi, Ryan Asby, Maria Erendira Calleja-Cervantes, David Lara-Astiaso, Nicola K. Wilson, Rebecca Hannah, Jaana Bagri, Elsa Barnard, Sarah J Horton, Berthold Gottgens, Elli Papaemmanuil, Shuchi Agrawal Singh, Malgorzata Gozdecka, George S Vassiliou, Brian J P Huntly

Blood (2024) 144 (Supplement 1): 190.

https://doi.org/10.1182/blood-2024-201612

Published: 2024

Journal Articles

Acute Resistance to BET Inhibitors Remodels Compensatory Transcriptional Programs Via p300 Co-Activation

Blood (2024) 144 (Supplement 1): 722.

https://doi.org/10.1182/blood-2024-202515

Published: 2024

Journal Articles

HOXA9 forms a repressive complex with nuclear matrix–associated protein SAFB to maintain acute myeloid leukemia

Shuchi Agrawal-Singh, Jaana Bagri, George Giotopoulos, Dhoyazan M. A. Azazi, Sarah J. Horton, Cecile K. Lopez, Shubha Anand, Anne-Sophie Bach, Frances Stedham, Robin Antrobus, Jack W. Houghton, George S. Vassiliou, Daniel Sasca, Haiyang Yun, Anthony D. Whetton, Brian J. P. Huntly

Blood (2023) 141 (14): 1737–1754.

https://doi.org/10.1182/blood.2022016528

Published: 2023

Includes: Supplemental data

Journal Articles

HOXA9 Nucleates a Repressive Chromatin Complex with Nuclear Matrix-Associated Protein- Safb to Maintain Acute Myeloid Leukemia

Shuchi Agrawal Singh, Jaana Bagri, George Giotopoulos, Eshwar Meduri, Shubha Anad, Sarah J. Horton, Daniel Sasca, Haiyang Yun, Anthony Whetton, Brian James Patrick Huntly

Blood (2022) 140 (Supplement 1): 720–721.

https://doi.org/10.1182/blood-2022-156341

Published: 2022

Journal Articles

Mutational Synergy Coordinately Remodels Chromatin Accessibility, Enhancer Landscape and 3-Dimensional DNA Topology to Alter Gene Expression during Leukemia Induction

Haiyang Yun, PhD, Shabana Vohra, PhD, Annalisa Mupo, PhD, George Giotopoulos, PhD, Daniel Sasca, MD, Sarah J. Horton, PhD, Shuchi Agrawal-Singh, PhD, Eshwar Meduri, PhD, Faisal Basheer, MBBChir, MA, PhD, Ludovica Marando, Malgorzata Gozdecka, PhD, Oliver M. Dovey, PhD, Xiaonan Wang, PhD, Paolo Gallipoli, PhD, Cameron Osborne, PhD, George S. Vassiliou, FRCPath, MRCP, PhD, Brian J. P. Huntly, PhD MRCP, MB, FRCPath

Blood (2019) 134 (Supplement_1): 278.

https://doi.org/10.1182/blood-2019-122413

Published: 2019

Journal Articles

DNA methylation changes are a late event in acute promyelocytic leukemia and coincide with loss of transcription factor binding

Blood (2013) 121 (1): 178–187.

https://doi.org/10.1182/blood-2012-08-448860

Published: 2013

Includes: Supplemental data

Journal Articles

Genome-wide analysis of histone H3 acetylation patterns in AML identifies PRDX2 as an epigenetically silenced tumor suppressor gene

Blood (2012) 119 (10): 2346–2357.

https://doi.org/10.1182/blood-2011-06-358705

Published: 2012

Includes: Supplemental data

Journal Articles

Profiling of histone H3 lysine 9 trimethylation levels predicts transcription factor activity and survival in acute myeloid leukemia

Blood (2010) 116 (18): 3564–3571.

https://doi.org/10.1182/blood-2009-09-240978

Published: 2010

Includes: Supplemental data

Journal Articles

Pim2 cooperates with PML-RARα to induce acute myeloid leukemia in a bone marrow transplantation model

Shuchi Agrawal-Singh, Steffen Koschmieder, Sandra Gelsing, Carol Stocking, Martin Stehling, Christian Thiede, Nils H. Thoennissen, Gabriele Köhler, Peter J. M. Valk, Ruud Delwel, Ken Mills, Nicole Bäumer, Lara Tickenbrock, Klaus Hansen, Wolfgang E. Berdel, Carsten Müller-Tidow, Hubert Serve

Blood (2010) 115 (22): 4507–4516.

https://doi.org/10.1182/blood-2009-03-210070

Published: 2010

Includes: Supplemental data

Journal Articles

Mtss1 Suppresses BCR-ABL Induced Cell Migration and Is Downregulated in CML Stem Cells.

Mirle Schemionek, Shuchi Agrawal, PhD, Martin Stehling, PhD, Daniel G. Tenen, MD, Ashley Hamilton, Tessa Holyoake, MD, PhD, Ulrich Steidl, MD, PhD, Wolfgang E. Berdel, MD, Albrecht Schwab, MD, Carsten Müller-Tidow, MD, Steffen Koschmieder, MD

Blood (2008) 112 (11): 1077.

https://doi.org/10.1182/blood.V112.11.1077.1077

Published: 2008

Journal Articles

ChIP-Chip in Primary AML Blasts Identifies Peroxiredoxin-II as An Epigenetically Silenced Tumor Suppressor.

Shuchi Agrawal-Singh, Markus Wiechmann, Sandra Doths, Christina Nolte, Nils Heinrich Thoennissen, Hans-Ulrich Klein, Martin Dugas, MD, Wolfgang E. Berdel, Steffen Koschmieder, MD, Hubert Serve, MD, PhD, Carsten Mueller-Tidow

Blood (2008) 112 (11): 3351.

https://doi.org/10.1182/blood.V112.11.3351.3351

Published: 2008

Journal Articles

Chromatin modifications induced by PML-RARα repress critical targets in leukemogenesis as analyzed by ChIP-Chip

Claudia Hoemme, Abdul Peerzada, Gerhard Behre, Yipeng Wang, Michael McClelland, Kay Nieselt, Matthias Zschunke, Christine Disselhoff, Shuchi Agrawal, Fabienne Isken, Nicola Tidow, Wolfgang E. Berdel, Hubert Serve, Carsten Müller-Tidow

Blood (2008) 111 (5): 2887–2895.

https://doi.org/10.1182/blood-2007-03-079921

Published: 2008

Includes: Supplemental data

Journal Articles

The C/EBPδ tumor suppressor is silenced by hypermethylation in acute myeloid leukemia

Shuchi Agrawal, Wolf-Karsten Hofmann, Nicola Tidow, Mathias Ehrich, Dirk van den Boom, Steffen Koschmieder, Wolfgang E. Berdel, Hubert Serve, Carsten Müller-Tidow

Blood (2007) 109 (9): 3895–3905.

https://doi.org/10.1182/blood-2006-08-040147

Published: 2007

Includes: Supplemental data

Journal Articles

Decitabine and Vitamin D3 Differentially Increase C-Jun, PU.1, and Sp1 Hematopoietic Transcription Factors To Induce Monocytic Differentiation.

Steffen Koschmieder, MD, Shuchi Agrawal, Hanna S. Radomska, PhD, Claudia S. Huettner, PhD, Daniel G. Tenen, MD, Oliver G. Ottmann, MD, Wolfgang E. Berdel, MD, Hubert L. Serve, MD, Carsten Mueller-Tidow, MD

Blood (2006) 108 (11): 2223.

https://doi.org/10.1182/blood.V108.11.2223.2223

Published: 2006

Journal Articles

Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations

Masao Mizuki, Joachim Schwäble, Claudia Steur, Chunaram Choudhary, Shuchi Agrawal, Bülent Sargin, Björn Steffen, Itaru Matsumura, Yuzuru Kanakura, Frank D. Böhmer, Carsten Müller-Tidow, Wolfgang E. Berdel, Hubert Serve

Blood (2003) 101 (8): 3164–3173.

https://doi.org/10.1182/blood-2002-06-1677

Published: 2003

NARROW

Acute resistance to BET inhibitors remodels compensatory transcriptional programs via p300 coactivation

Delayed Trp53 Activation Protects Dnmt3a -Mutant Haematopoietic Stem Cells from Inflammatory Attrition

Acute Resistance to BET Inhibitors Remodels Compensatory Transcriptional Programs Via p300 Co-Activation

HOXA9 forms a repressive complex with nuclear matrix–associated protein SAFB to maintain acute myeloid leukemia

HOXA9 Nucleates a Repressive Chromatin Complex with Nuclear Matrix-Associated Protein- Safb to Maintain Acute Myeloid Leukemia

Mutational Synergy Coordinately Remodels Chromatin Accessibility, Enhancer Landscape and 3-Dimensional DNA Topology to Alter Gene Expression during Leukemia Induction

DNA methylation changes are a late event in acute promyelocytic leukemia and coincide with loss of transcription factor binding

Genome-wide analysis of histone H3 acetylation patterns in AML identifies PRDX2 as an epigenetically silenced tumor suppressor gene

Profiling of histone H3 lysine 9 trimethylation levels predicts transcription factor activity and survival in acute myeloid leukemia

Pim2 cooperates with PML-RARα to induce acute myeloid leukemia in a bone marrow transplantation model

Mtss1 Suppresses BCR-ABL Induced Cell Migration and Is Downregulated in CML Stem Cells.

ChIP-Chip in Primary AML Blasts Identifies Peroxiredoxin-II as An Epigenetically Silenced Tumor Suppressor.

Chromatin modifications induced by PML-RARα repress critical targets in leukemogenesis as analyzed by ChIP-Chip

The C/EBPδ tumor suppressor is silenced by hypermethylation in acute myeloid leukemia

Decitabine and Vitamin D3 Differentially Increase C-Jun, PU.1, and Sp1 Hematopoietic Transcription Factors To Induce Monocytic Differentiation.

Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations

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American Society of Hematology

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American Society of Hematology

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