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Journal Articles

Two Novel Distinct Subtypes of Myeloid Neoplasms Molecularly Associated with Histone H3K36 Methylations

Blood (2015) 126 (23): 2841.

https://doi.org/10.1182/blood.V126.23.2841.2841

Published: 2015

Journal Articles

DDX41 Is a Tumor Suppressor Gene Associated with Inherited and Acquired Mutations

Blood (2014) 124 (21): 125.

https://doi.org/10.1182/blood.V124.21.125.125

Published: 2014

Journal Articles

Identification of CAR As a Novel Mediator of Erythroid Differentiation and Migration That Is Specifically Downregulated in Erythropoietic Progenitor Cells in Patients with MDS

Karin Bauer, PhD, Sigrid Machherndl-Spandl, MD, Susanne Suessner, MSc, Martin Danzer, MSc, Johannes Pröll, PhD, Jeroen Lauf, Gregor Eisenwort, MD PhD, Wolfgang R. Sperr, MD, Hans-Ulrich Klein, PhD, Gregor Hoermann, MD PhD, Norman Häfner, PhD, Marie Bene, PharmSciD, PhD, Uwe Platzbecker, MD, Ansgar Weltermann, MD, Christian Gabriel, MD, Ulrich Germing, Peter Bettelheim, MD, Peter Valent, MD

Blood (2014) 124 (21): 1570.

https://doi.org/10.1182/blood.V124.21.1570.1570

Published: 2014

Journal Articles

Exome Sequencing Of Paired Chronic-Blast Phase Samples In Myeloproliferative Neoplasms Reveals High Frequency Of Rare Germline Sequence Variants In TYK2 and Novel Blast Phase-Restricted Mutations

Nils H. Thoennissen, MD, Isabell Schulze, Terra L Lasho, MT, (ASCP), Georg Evers, MD, Gabriela B. Thoennissen, MD, Hans-Ulrich Klein, PhD, Martin Dugas, PhD, Wolfgang E. Berdel, MD, Carsten Müller-Tidow, MD, Animesh Pardanani, MBBS, PhD, Ayalew Tefferi, MD

Blood (2013) 122 (21): 2849.

https://doi.org/10.1182/blood.V122.21.2849.2849

Published: 2013

Journal Articles

Abnormal Expression Of The Major Coxsackie-Adenovirus Receptor CAR On Immature Dysplastic CD105+ Erythroid Progenitor Cells In Patients With MDS and Related Bone Marrow Neoplasms

Sigrid Machherndl-Spandl, MD, Susanne Suessner, Martin Danzer, Johannes Proell, Christian Gabriel, MD, Jeroen Lauf, Gregor Eisenwort, Wolfgang R Sperr, M.D., Peter Valent, Hans-Ulrich Klein, PhD, Marie-Christine Bene, PharmSciD, PhD, Ulrich Germing, MD, Uwe Platzbecker, MD, PhD, Ansgar Weltermann, MD, Otto Zach, PhD, Peter Bettelheim, MD

Blood (2013) 122 (21): 2818.

https://doi.org/10.1182/blood.V122.21.2818.2818

Published: 2013

Journal Articles

Landscape Of Genetic Lesions In 944 Patients With Myelodysplastic Syndromes

Blood (2013) 122 (21): 521.

https://doi.org/10.1182/blood.V122.21.521.521

Published: 2013

Journal Articles

Genomic instability may originate from imatinib-refractory chronic myeloid leukemia stem cells

Elisabeth Bolton-Gillespie, Mirle Schemionek, Hans-Ulrich Klein, Sylwia Flis, Grazyna Hoser, Thoralf Lange, Margaret Nieborowska-Skorska, Jacqueline Maier, Linda Kerstiens, Mateusz Koptyra, Martin C. Müller, Hardik Modi, Tomasz Stoklosa, Ilona Seferynska, Ravi Bhatia, Tessa L. Holyoake, Steffen Koschmieder, Tomasz Skorski

Blood (2013) 121 (20): 4175–4183.

https://doi.org/10.1182/blood-2012-11-466938

Published: 2013

Includes: Supplemental data

Journal Articles

DNA methylation changes are a late event in acute promyelocytic leukemia and coincide with loss of transcription factor binding

Blood (2013) 121 (1): 178–187.

https://doi.org/10.1182/blood-2012-08-448860

Published: 2013

Includes: Supplemental data

Journal Articles

Genome-wide analysis of histone H3 acetylation patterns in AML identifies PRDX2 as an epigenetically silenced tumor suppressor gene

Blood (2012) 119 (10): 2346–2357.

https://doi.org/10.1182/blood-2011-06-358705

Published: 2012

Includes: Supplemental data

Journal Articles

Whole-exome sequencing identifies somatic mutations of BCOR in acute myeloid leukemia with normal karyotype

Blood (2011) 118 (23): 6153–6163.

https://doi.org/10.1182/blood-2011-07-365320

Published: 2011

Includes: Supplemental data

Journal Articles

Identification of the PML-RARα Associated DNA Methylome Using Reduced Representation Bisulfite Sequencing in Primary Patient Samples

Christian Rohde, PhD, Till Schoofs, Katja Hebestreit, Hans-Ulrich Klein, PhD, Anika Witten, PhD, Monika Stoll, PhD, Eva Lengfelder, MD, Wolf-Karsten Hofmann, MD, Peter Schlenke, PhD, Stefanie Göllner, PhD, Thomas Büchner, MD, Maria Cristina Sauerland, Steffen Koschmieder, MD, Wolfgang E. Berdel, Martin Dugas, MD, Carsten Müller-Tidow, MD

Blood (2011) 118 (21): 2436.

https://doi.org/10.1182/blood.V118.21.2436.2436

Published: 2011

Journal Articles

EZH2 Mutations Can Be Detected in 23% of t(10;11)(p13;q14)/ PICALM-MLLT10 Positive Acute Leukemias,

Vera Grossmann, MSc, Ulrike Bacher, MD, Valentina Artusi, MSc, Hans-Ulrich Klein, PhD, Wolfgang Kern, MD, Susanne Schnittger, PhD, Torsten Haferlach, MD, Alexander Kohlmann, PhD, Claudia Haferlach, MD

Blood (2011) 118 (21): 3440.

https://doi.org/10.1182/blood.V118.21.3440.3440

Published: 2011

Journal Articles

Whole Genome Amplification with Subsequent High Throughput Sequencing Allows Comprehensive Genome-Wide Analysis of Single Leukemic Cells

Vera Binder, MD, Christoph Bartenhagen, Vera Okpanyi, PhD, Bianca Behrens, Birte Moehlendick, PhD, Hans-Ulrich Klein, PhD, Harald Rieder, MD, Michael Gombert, PhD, Martin Dugas, MD, Nikolas Hendrik Stoecklein, MD, Arndt Borkhardt, MD

Blood (2011) 118 (21): 1437.

https://doi.org/10.1182/blood.V118.21.1437.1437

Published: 2011

Journal Articles

Genomic Instability Originates From Leukemia Stem Cells in a Mouse Model of CML-CP

Elisabeth Bolton, Mirle Schemionek, PhD, Hans-Ulrich Klein, Linda Kerstiens, Steffen Koschmieder, MD, Tomasz Skorski, MD, PhD

Blood (2011) 118 (21): 445.

https://doi.org/10.1182/blood.V118.21.445.445

Published: 2011

Journal Articles

Histone H3 Methylation Mediates All- Trans -Retinoic Acid Responsiveness in Acute Myeloid Leukemia

Tino Schenk, PhD, Stefanie Göllner, PhD, Weihsu Claire Chen, PhD, Louise Howell, BSc, Liqing Jin, MD, Katja Hebestreit, Hans-Ulrich Klein, PhD, Alan K Burnett, MD, Ken I. Mills, PhD, FRCPath, Laurence Marton, MD, Robert Casero, Jr., PhD, Patrick Woster, PhD, Martin Dugas, MD, Jean C.Y. Wang, MD, PhD, John E. Dick, PhD, Carsten Müller-Tidow, MD, Kevin Petrie, PhD, Arthur Zelent, PhD

Blood (2011) 118 (21): 224.

https://doi.org/10.1182/blood.V118.21.224.224

Published: 2011

Journal Articles

Targeted Next-Generation Sequencing and Genome-Wide High-Resolution Copy Number DNA Arrays Allow the Identification of Five Novel RUNX1 Fusions In Hematological Malignancies.

Vera Grossmann, Alexander Kohlmann, PhD, Hans-Ulrich Klein, MA, Sonja Schindela, Susanne Schnittger, PhD, Martin Dugas, MD, Wolfgang Kern, MD, Torsten Haferlach, MD, Claudia Haferlach, MD

Blood (2010) 116 (21): 1193.

https://doi.org/10.1182/blood.V116.21.1193.1193

Published: 2010

Journal Articles

Global Identification of Genomic Structural Variants In Childhood ETV6/RUNX1 ( TEL/AML1 ) Acute Lymphoblastic Leukemias by Mate-Pair Massively Parallel Sequencing.

Vera Okpanyi, Christoph Bartenhagen, Michael Gombert, PhD, Vera Binder, MD, Hans-Ulrich Klein, MA, Silja Roettgers, PhD, Jochen Harbott, PhD, Martin Dugas, MD, Arndt Borkhardt, MD

Blood (2010) 116 (21): 3364.

https://doi.org/10.1182/blood.V116.21.3364.3364

Published: 2010

Journal Articles

Robust and Sensitive Detection of Insertions, Deletions and Point Mutations In CEBPA , a GC-Rich Content Gene, Using 454 Next-Generation Deep-Sequencing (NGS).

Vera Grossmann, MA, Susanne Schnittger, PhD, Sonja Schindela, Hans-Ulrich Klein, MA, Christiane Eder, PhD, Martin Dugas, MD, Wolfgang Kern, MD, Claudia Haferlach, MD, Torsten Haferlach, MD, Alexander Kohlmann, PhD

Blood (2010) 116 (21): 1657.

https://doi.org/10.1182/blood.V116.21.1657.1657

Published: 2010

Journal Articles

Targeted Next-Generation Sequencing (NGS) Enables a Broad Screening of 95 Molecular Mutations In a One-Step Approach and Detects Recurrent Mutations In AML with a Normal Karyotype In MYH11 and NOTCH1

Alexander Kohlmann, PhD, Vera Grossmann, MA, Hans-Ulrich Klein, MA, Susanne Schnittger, PhD, Martin Dugas, MD, Wolfgang Kern, MD, Claudia Haferlach, MD, Torsten Haferlach, MD

Blood (2010) 116 (21): 175.

https://doi.org/10.1182/blood.V116.21.175.175

Published: 2010

Journal Articles

The Interlaboratory RObustness of Next-Generation Sequencing (IRON) Study: Deep-Sequencing Investigating TET2 , CBL , and KRAS Mutations In 4464 Amplicons by An International Group Involving 8 Laboratories.

Blood (2010) 116 (21): 1665.

https://doi.org/10.1182/blood.V116.21.1665.1665

Published: 2010

NARROW

Two Novel Distinct Subtypes of Myeloid Neoplasms Molecularly Associated with Histone H3K36 Methylations

DDX41 Is a Tumor Suppressor Gene Associated with Inherited and Acquired Mutations

Identification of CAR As a Novel Mediator of Erythroid Differentiation and Migration That Is Specifically Downregulated in Erythropoietic Progenitor Cells in Patients with MDS

Exome Sequencing Of Paired Chronic-Blast Phase Samples In Myeloproliferative Neoplasms Reveals High Frequency Of Rare Germline Sequence Variants In TYK2 and Novel Blast Phase-Restricted Mutations

Abnormal Expression Of The Major Coxsackie-Adenovirus Receptor CAR On Immature Dysplastic CD105+ Erythroid Progenitor Cells In Patients With MDS and Related Bone Marrow Neoplasms

Landscape Of Genetic Lesions In 944 Patients With Myelodysplastic Syndromes

Genomic instability may originate from imatinib-refractory chronic myeloid leukemia stem cells

DNA methylation changes are a late event in acute promyelocytic leukemia and coincide with loss of transcription factor binding

Genome-wide analysis of histone H3 acetylation patterns in AML identifies PRDX2 as an epigenetically silenced tumor suppressor gene

Whole-exome sequencing identifies somatic mutations of BCOR in acute myeloid leukemia with normal karyotype

Identification of the PML-RARα Associated DNA Methylome Using Reduced Representation Bisulfite Sequencing in Primary Patient Samples

EZH2 Mutations Can Be Detected in 23% of t(10;11)(p13;q14)/ PICALM-MLLT10 Positive Acute Leukemias,

Whole Genome Amplification with Subsequent High Throughput Sequencing Allows Comprehensive Genome-Wide Analysis of Single Leukemic Cells

Genomic Instability Originates From Leukemia Stem Cells in a Mouse Model of CML-CP

Histone H3 Methylation Mediates All- Trans -Retinoic Acid Responsiveness in Acute Myeloid Leukemia

Targeted Next-Generation Sequencing and Genome-Wide High-Resolution Copy Number DNA Arrays Allow the Identification of Five Novel RUNX1 Fusions In Hematological Malignancies.

Global Identification of Genomic Structural Variants In Childhood ETV6/RUNX1 ( TEL/AML1 ) Acute Lymphoblastic Leukemias by Mate-Pair Massively Parallel Sequencing.

Robust and Sensitive Detection of Insertions, Deletions and Point Mutations In CEBPA , a GC-Rich Content Gene, Using 454 Next-Generation Deep-Sequencing (NGS).

Targeted Next-Generation Sequencing (NGS) Enables a Broad Screening of 95 Molecular Mutations In a One-Step Approach and Detects Recurrent Mutations In AML with a Normal Karyotype In MYH11 and NOTCH1

The Interlaboratory RObustness of Next-Generation Sequencing (IRON) Study: Deep-Sequencing Investigating TET2 , CBL , and KRAS Mutations In 4464 Amplicons by An International Group Involving 8 Laboratories.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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