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Journal Articles

Clonal landscape and clinical outcomes of telomere biology disorders: somatic rescue and cancer mutations

Blood (2024) 144 (23): 2402–2416.

https://doi.org/10.1182/blood.2024025023

Published: 2024

Includes: Supplemental data

Journal Articles

Danazol Treatment for Telomere Biology Disorders: Long-Term Results of a Phase I/II Study

Nicholas C. Lee, Fernanda Gutierrez-Rodrigues, Ruba Shalhoub, Tania Rene Machado, Jennifer Lotter, Lemlem Alemu, Diego Quinones Raffo, Geraldine Aubert, Colin O. Wu, Bhavisha A. Patel, Neal S. Young, Emma M. Groarke

Blood (2024) 144 (Supplement 1): 439.

https://doi.org/10.1182/blood-2024-194335

Published: 2024

Journal Articles

Trial in Progress: A Phase I/II Study of the JAK1/2 Inhibitor Ruxolitinib for Relapsed/Refractory Immune Bone Marrow Failure

Emma M. Groarke, Jennifer Lotter, Ivana Darden, Alfiya Bikineyeva, Uzoamaka Okeke, Rachel Blair, Julie Erb-Alvarez, Jichun Chen, Xingmin Feng, Jibran Durrani, Neal S. Young, Bhavisha A. Patel

Blood (2024) 144 (Supplement 1): 1323.1.

https://doi.org/10.1182/blood-2024-199789

Published: 2024

Journal Articles

T Cell Receptor Clonal Dynamics and Hematopoietic Recovery after Immunotherapy in Severe Aplastic Anemia

Zhijie Wu, Shouguo Gao, Xingmin Feng, Haoran Li, Nicolas Sompairac, Shirin Jamshidi, Desmond Choy, Rita Antunes Dos Reis, Qingyan Gao, Sachiko Kajigaya, Lemlem Alemu, Diego Quinones Raffo, Emma M. Groarke, Shahram Kordasti, Bhavisha A. Patel, Neal S. Young

Blood (2024) 144 (Supplement 1): 34.

https://doi.org/10.1182/blood-2024-203468

Published: 2024

Journal Articles

Single-Cell Multi-Omics Analysis Reveals Dysfunctional Features of the Immune Responses in Vexas Syndrome

Hiroki Mizumaki, Shouguo Gao, Zhijie Wu, Xingmin Feng, Fernanda Gutierrez-Rodrigues, Lemlem Alemu, Diego Quinones Raffo, Ivana Darden, Sachiko Kajigaya, Emma M. Groarke, Neal S. Young, Bhavisha A. Patel

Blood (2024) 144 (Supplement 1): 4056.

https://doi.org/10.1182/blood-2024-198166

Published: 2024

Journal Articles

The Impact of Body Mass Index (BMI) in Patients with Aplastic Anemia Receiving Weight-Adjusted Horse Anti-Thymocyte Globulin (hATG) on Outcome, Response and Relapse Rate

Jeanette Walter, Benjamin Rolles, Yannic Schumacher, Frauke Theis, Leo Hansmann, Markus P. Radsak, Michael Heuser, Julia-Annabell Georgi, Jörg Chromik, Beatrice Drexler, Jörg Schubert, Kim Kricheldorf, Jens Panse, Thomas Stiehl, Tim H. H. Brummendorf, Bhavisha A. Patel, Neal S. Young, Emma M. Groarke, Fabian Beier

Blood (2024) 144 (Supplement 1): 4082.

https://doi.org/10.1182/blood-2024-207190

Published: 2024

Journal Articles

Longitudinal Contribution of Distinct Hematopoietic Clones during Marrow Recovery in Immune Aplastic Anemia

Fernanda Gutierrez-Rodrigues, Emma M. Groarke, Lemlem Alemu, Olga Rios, Diego Quinones Raffo, Jennifer Lotter, Neal S. Young, Bhavisha A. Patel

Blood (2024) 144 (Supplement 1): 32.

https://doi.org/10.1182/blood-2024-206215

Published: 2024

Journal Articles

Complement Mediated Immune Activation in HLA Class I Alloimmunized Immune Aplastic Anemia Imputed from Single Cell Analysis of Peripheral Cell Subsets

Jibran Durrani, Leonard Chen, Nuri Cha, Zhijie Wu, Shouguo Gao, Hiroki Mizumaki, Jennifer Lotter, Olga Rios, Colin O. Wu, Willy Albert Flegel, Neal S. Young, Emma M. Groarke, Bhavisha A. Patel

Blood (2024) 144 (Supplement 1): 2693.

https://doi.org/10.1182/blood-2024-200879

Published: 2024

Journal Articles

Novel Germline ZCCHC8 Mutations Causes Dyskeratosis Congenita with Genetic Rescue By Uniparental Disomy of Chromosome 12q

Flavia S. Donaires, Sophie de Tocqueville, Marilia Bazzo Catto, Luiz Fernando Bazzo Catto, Emma M. Groarke, Barbara A. Santana, Settara C Chandrasekharappa, Frank X. Donovan, Carine Halfon-Domenech, Neal S. Young, Caroline Kannengiesser, Rodrigo T. Calado, Patrick Revy, Fernanda Gutierrez-Rodrigues

Blood (2024) 144 (Supplement 1): 1330.

https://doi.org/10.1182/blood-2024-205711

Published: 2024

Journal Articles

DNMT3A Mutant Clonal Hematopoiesis in Vexas Syndrome Epigenetically Potentiates IL-13 and IL-15 Inflammatory Pathways and Is Associated with Increased Mortality

Blood (2024) 144 (Supplement 1): 2686.

https://doi.org/10.1182/blood-2024-204334

Published: 2024

Journal Articles

Different Effects of Selective Janus Kinase (JAK) Inhibitors in Murine Bone Marrow Failure

Jibran Durrani, Xingmin Feng, Joshua Glass, Zhijie Wu, Shouguo Gao, Bhavisha A. Patel, Jichun Chen, Neal S. Young, Emma M. Groarke

Blood (2024) 144 (Supplement 1): 1309.

https://doi.org/10.1182/blood-2024-193762

Published: 2024

Journal Articles

CSF1 Receptor Inhibition Augments Murine Immune Bone Marrow Failure: New Evidence Indicative of M1-Type Macrophage Polarization Driving Hematopoietic Failure

Joshua Glass, Xingmin Feng, Jichun Chen, Neal S. Young

Blood (2024) 144 (Supplement 1): 1308.

https://doi.org/10.1182/blood-2024-193143

Published: 2024

Journal Articles

Patient Reported Outcomes in Vexas Syndrome

Bhavisha A. Patel, Emma M. Groarke, Ruba Shalhoub, Fernanda Rodrigues, Alice Fike, Kaitlin Quinn, Ivana Darden, Shanni Liu, Wendy Goodspeed, Rui Miao, Colin O. Wu, Neal S. Young, Peter C Grayson

Blood (2024) 144 (Supplement 1): 3711.

https://doi.org/10.1182/blood-2024-205755

Published: 2024

Journal Articles

Venous and arterial thrombosis in patients with VEXAS syndrome

Blood (2024) 143 (21): 2190–2200.

https://doi.org/10.1182/blood.2023022329

Published: 2024

Includes: Supplemental data

Journal Articles

Megakaryocytes Have Immune Characteristics in Murine Immune Bone Marrow Failure

Ashvind Prabahran, Ash Lee Manley, Zhijie Wu, Shouguo Gao, Hiroki Mizumaki, Christian Combs, Jichun Chen, Xingmin Feng, Neal S. Young

Blood (2023) 142 (Supplement 1): 1349.

https://doi.org/10.1182/blood-2023-174597

Published: 2023

Journal Articles

Early Initiation of Oral Therapy with Cyclosporine and Eltrombopag for Treatment Naïve Severe Aplastic Anemia: Interim Results of a Phase II Trial

Bhavisha A. Patel, Emma M. Groarke, Ruba Shahloub, Jennifer Lotter, Jeanine Superata, Joelle Khoriaty, Kimberly McKernan, Uzoamaka Okeke, Olga Rios, Colin O. Wu, Neal S. Young

Blood (2023) 142 (Supplement 1): 2711.

https://doi.org/10.1182/blood-2023-181071

Published: 2023

Journal Articles

Clinical Manifestations Are Evolving and Progressive in Patients with Vexas Syndrome

Bhavisha A. Patel, Marcela Ferrada, Kaitlin Quinn, Kristy Freeman, Ivana Darden, Wendy Goodspeed, Lisa Duncan, Roxanne Merkel, Alice Fike, Peter C Grayson, Neal S. Young, Emma M. Groarke

Blood (2023) 142 (Supplement 1): 703.

https://doi.org/10.1182/blood-2023-187454

Published: 2023

Journal Articles

Clonal Bone Marrow Plasma Cells Are Common in Patients with Vexas Syndrome

Alina Dulau-Florea, Raul C. Braylan, Yanna Ding, Nisha Patel, Katherine Calvo, Elizabeth Hill, Emma M. Groarke, Neal S. Young, Bhavisha A. Patel

Blood (2023) 142 (Supplement 1): 4681.

https://doi.org/10.1182/blood-2023-186736

Published: 2023

Journal Articles

Characterization of Hematopoietic Stem and Progenitor Cells of PNH Patients Using Single-Cell RNA Sequencing Analysis

Hiroki Mizumaki, Shouguo Gao, Zhijie Wu, Emma M. Groarke, Lemlem Alemu, Diego Quinones Raffo, Olga Rios, Sachiko Kajigaya, Bhavisha A. Patel, Neal S. Young

Blood (2023) 142 (Supplement 1): 4085.

https://doi.org/10.1182/blood-2023-181078

Published: 2023

Journal Articles

Ahemolytic PNH: Clinical Features of a Distinct Phenotype of Paroxysmal Nocturnal Hemoglobinuria

Zehra Tombul, Waled Bahaj, Merve Ozturk, Bhavisha A. Patel, Alina Dulau-Florea, Ahmet Celal Toprak, Ibrahim F. Ibrahim, Weina Chen, Franklin Fuda, Olisaemeka Ogbue, Carmelo Gurnari, Charles Parker, Neal S. Young, Jaroslaw P. Maciejewski, Munevver Duran, Taha Bat

Blood (2023) 142 (Supplement 1): 1352.

https://doi.org/10.1182/blood-2023-186528

Published: 2023

NARROW

Clonal landscape and clinical outcomes of telomere biology disorders: somatic rescue and cancer mutations

Danazol Treatment for Telomere Biology Disorders: Long-Term Results of a Phase I/II Study

Trial in Progress: A Phase I/II Study of the JAK1/2 Inhibitor Ruxolitinib for Relapsed/Refractory Immune Bone Marrow Failure

T Cell Receptor Clonal Dynamics and Hematopoietic Recovery after Immunotherapy in Severe Aplastic Anemia

Single-Cell Multi-Omics Analysis Reveals Dysfunctional Features of the Immune Responses in Vexas Syndrome

The Impact of Body Mass Index (BMI) in Patients with Aplastic Anemia Receiving Weight-Adjusted Horse Anti-Thymocyte Globulin (hATG) on Outcome, Response and Relapse Rate

Longitudinal Contribution of Distinct Hematopoietic Clones during Marrow Recovery in Immune Aplastic Anemia

Complement Mediated Immune Activation in HLA Class I Alloimmunized Immune Aplastic Anemia Imputed from Single Cell Analysis of Peripheral Cell Subsets

Novel Germline ZCCHC8 Mutations Causes Dyskeratosis Congenita with Genetic Rescue By Uniparental Disomy of Chromosome 12q

DNMT3A Mutant Clonal Hematopoiesis in Vexas Syndrome Epigenetically Potentiates IL-13 and IL-15 Inflammatory Pathways and Is Associated with Increased Mortality

Different Effects of Selective Janus Kinase (JAK) Inhibitors in Murine Bone Marrow Failure

CSF1 Receptor Inhibition Augments Murine Immune Bone Marrow Failure: New Evidence Indicative of M1-Type Macrophage Polarization Driving Hematopoietic Failure

Patient Reported Outcomes in Vexas Syndrome

Venous and arterial thrombosis in patients with VEXAS syndrome

Megakaryocytes Have Immune Characteristics in Murine Immune Bone Marrow Failure

Early Initiation of Oral Therapy with Cyclosporine and Eltrombopag for Treatment Naïve Severe Aplastic Anemia: Interim Results of a Phase II Trial

Clinical Manifestations Are Evolving and Progressive in Patients with Vexas Syndrome

Clonal Bone Marrow Plasma Cells Are Common in Patients with Vexas Syndrome

Characterization of Hematopoietic Stem and Progenitor Cells of PNH Patients Using Single-Cell RNA Sequencing Analysis

Ahemolytic PNH: Clinical Features of a Distinct Phenotype of Paroxysmal Nocturnal Hemoglobinuria

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American Society of Hematology

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American Society of Hematology

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