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Paula Rodríguez Otero
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Journal Articles

Ide-cel vs standard regimens in triple-class–exposed relapsed and refractory multiple myeloma: updated KarMMa-3 analyses

Clinical Trials & Observations
Sikander Ailawadhi, Bertrand Arnulf, Krina Patel, Michele Cavo, Ajay K. Nooka, Salomon Manier, Natalie Callander, Luciano J. Costa, Ravi Vij, Nizar J. Bahlis, Philippe Moreau, Scott Solomon, Ingerid Weum Abrahamsen, Rachid Baz, Annemiek Broijl, Christine Chen, Sundar Jagannath, Noopur Raje, Christof Scheid, Michel Delforge, Reuben Benjamin, Thomas Pabst, Shinsuke Iida, Jesús Berdeja, Sergio Giralt, Anna Truppel-Hartmann, Yanping Chen, Xiaobo Zhong, Fan Wu, Julia Piasecki, Laurie Eliason, Devender Dhanda, Jasper Felten, Andrea Caia, Mark Cook, Mihaela Popa McKiver, Paula Rodríguez-Otero
Journal: Blood
Blood (2024) 144 (23): 2389–2401.
https://doi.org/10.1182/blood.2024024582
Published: 2024
Includes: Supplemental data
Journal Articles

Large B-Cell Lymphoma in Elderly Patients: Completing Treatment Showed Impact on Overall Survival, a Real World Evidence

Victoria Wauters, Carolina Valeria Mahuad, Gonzalo Martin Garate, Maria De Los Angeles Vicente Reparaz, Florencia Aizpurua, Marta Elisa Zerga, Paula Rodriguez-Otero, Martina Rodriguez, Claudia Casali, Manuela Clavijo
Journal: Blood
Blood (2024) 144 (Supplement 1): 6440.
https://doi.org/10.1182/blood-2024-208904
Published: 2024
Journal Articles

Monumental-6: A Phase 3 Study of Talquetamab + Pomalidomide or Talquetamab + Teclistamab Vs Elotuzumab + Pomalidomide + Dexamethasone (EPd) or Pomalidomide + Bortezomib + Dexamethasone (PVd) in Patients with Relapsed/Refractory Multiple Myeloma Who Received 1-4 Prior Lines of Therapy, Including Lenalidomide and an Anti-CD38 Monoclonal Antibody

Ajay K. Nooka, Hira Mian, Cindy Lee, Paula Rodríguez-Otero, Shaji Kumar, Hermann Einsele, Deeksha Vishwamitra, Diego Vieyra, Colleen Kane, Michele Kosh, Tara J Masterson, Christoph Heuck, Ankit Kansagra, Philippe Moreau
Journal: Blood
Blood (2024) 144 (Supplement 1): 4757.1.
https://doi.org/10.1182/blood-2024-199752
Published: 2024
Journal Articles

Belantamab Mafodotin + Bortezomib + Dexamethasone Versus 2L+ Relapsed/Refractory Multiple Myeloma Regimens: Lenalidomide-Exposed, Lenalidomide-Refractory, High-Risk Cytogenic, and 2L-Only Subpopulations: A Network Meta-Analysis

Paula Rodríguez-Otero, Joshua Richter, Ajay K. Nooka, Fredrik Schjesvold, Emily Combe, Leanne Cooper, Ollie Schofield, Indeg Sly, Nick Ballew, Jacopo Bitetti, Natalie Boytsov, Simon McNamara, Molly Purser
Journal: Blood
Blood (2024) 144 (Supplement 1): 7054.
https://doi.org/10.1182/blood-2024-198712
Published: 2024
Journal Articles

An IFNγ-Mediated Immune Inflamed Microenvironment State in Multiple Myeloma with TP53 Loss That Can be Therapeutically Exploited

Marta Larrayoz, Elena Arriazu, Aintzane Zabaleta, Carmen Roncal, Ibon Tamayo, Diana Llopiz, Maddalen Jimenez, Carla Castro, Jon Celay, Carmen Vicente, Camila Guerrero, Sonia Sanz, Maria J Garcia-Barchino, Naroa Barrena, Noemi Puig, Maria Teresa Cedena Romero, Maria Jose Calasanz, Paula Rodríguez-Otero, Jesús F. San-Miguel, Mikel Hernaez, Xabier Agirre, Pablo Sarobe, Felipe Prosper, Bruno Paiva, Jose A. Martinez-Climent
Journal: Blood
Blood (2024) 144 (Supplement 1): 670.
https://doi.org/10.1182/blood-2024-194041
Published: 2024
Journal Articles

Phase I Study of Belantamab Mafodotin in Combination with Standard of Care in Transplant-Ineligible Newly Diagnosed Multiple Myeloma: Dreamm-9 Updated Interim Analysis

Saad Z. Usmani, Michal Mielnik, Mamta Garg, Irwindeep Sandhu, Al-Ola Abdallah, Youngil Koh, Albert Oriol, Hang Quach, Katja C. Weisel, Aranzazu Alonso Alonso, Enrique M Ocio, Wojciech Janowski, Chang-Ki Min, Karthik Ramasamy, Ricarda García Sánchez, Paula Rodríguez-Otero, Chris Brawley, Jacqueline L Egger, Morrys C Kaisermann, Marek Hus
Journal: Blood
Blood (2024) 144 (Supplement 1): 497.
https://doi.org/10.1182/blood-2024-198669
Published: 2024
Journal Articles

Depletion of Mature B Cells and of Normal Plasma Cells (PC) behind the Higher Incidence of Infections after Anti-BCMA VS Anti-GPRC5D Bispecific Antibodies (bsAb) in Relapsed Refractory Multiple Myeloma (RRMM)

Tomas Jelinek, David Zihala, Aintzane Zabaleta, Ioannis V Kostopoulos, Ondrej Soucek, Ondrej Venglar, Cristina Moreno, Despina Fotiou, Eva Radova, Luis-Esteban Tamariz-Amador, Foteini Theodorakakou, Ludmila Muronova, Andrea Manubens, Ourania Tsitsilonis, Tereza Popkova, Lucie Broskevicova, Jana Mihalyova, Tereza Sevcikova, Jesús F. San-Miguel, Meletios Dimopoulos, Paula Rodríguez-Otero, Jakub Radocha, Efstathios Kastritis, Bruno Paiva, Roman Hajek
Journal: Blood
Blood (2024) 144 (Supplement 1): 1934.
https://doi.org/10.1182/blood-2024-205481
Published: 2024
Journal Articles

Global Manufacturing Experience with Idecabtagene Vicleucel in Patients with Relapsed and Refractory Multiple Myeloma

Surbhi Sidana, Christof Scheid, Peter J. Mueller, Petra Schuberth, Hardik Modi, Peter Krengel, Romain Piault, Xiaobo Zhong, Paula Rodríguez-Otero
Journal: Blood
Blood (2024) 144 (Supplement 1): 3476.
https://doi.org/10.1182/blood-2024-194645
Published: 2024
Journal Articles

Cevostamab in Patients with Heavily Pretreated Relapsed/Refractory Multiple Myeloma (RRMM): Updated Results from an Ongoing Phase I Study Demonstrate Clinically Meaningful Activity and Manageable Safety and Inform the Doses and Regimen for Combination Studies

Joshua Richter, Sheeba K. Thomas, Amrita Y Krishnan, Jacob P. Laubach, Adam D. Cohen, Suzanne Trudel, Luciano J. Costa, Nizar J. Bahlis, Peter A. Forsberg, Rayan Kaedbey, Rafael Fonseca, Andrew Spencer, Paula Rodríguez-Otero, Maria-Victoria Mateos, Chihunt Wong, James Cooper, Tulika Tyagi, Rin Nakamura, Voleak Choeurng, Alexander M. Lesokhin
Journal: Blood
Blood (2024) 144 (Supplement 1): 1021.
https://doi.org/10.1182/blood-2024-199542
Published: 2024
Journal Articles

Unraveling Long-Term Survival of Multiple Myeloma Patients, the GEM2000 Experience

Rafael Alonso Fernandez, Andrés Arroyo Barea, Maria Teresa Cedena Romero, Laura Rosiñol Dachs, Javier de la Rubia, Sara Miqueleiz, Veronica Gonzalez-Calle, Felipe De Arriba, Luis Felipe Casado Montero, Miguel Teodoro Hernandez, Maria Mas Esteve, Pascual Fernandez, Paula Rodríguez-Otero, Carmen Calle Primo, Eugenia Abella, Paz Ribas, Adrian Alegre, Juan Miguel Bergua, Irene Gomez-Catalan, Jose Maria Arguiñano Perez, Luis Palomera, Enrique M Ocio, Maria Jose Busto Medina, Nieves Somolinos, Jose Maria Alonso Alonso, Aránzazu García Mateo, Joan Bargay, Pilar Delgado, Dunia De Miguel Llorente, Javier de la Cruz, Maria Victoria Mateos, Jesús F. San-Miguel, Joan Bladé, Juan-Jose Lahuerta Palacios, Joaquin Martinez Lopez
Journal: Blood
Blood (2024) 144 (Supplement 1): 1957.
https://doi.org/10.1182/blood-2024-211383
Published: 2024
Journal Articles

Health-Related Quality of Life in Transplant-Eligible Patients with Newly Diagnosed Multiple Myeloma: Data from the Perseus Trial of Subcutaneous Daratumumab Combined with Bortezomib, Lenalidomide, and Dexamethasone (D-VRd)

Pieter Sonneveld, Meletios A. Dimopoulos, Mario Boccadoro, Hang Quach, Phoebe Joy Ho, Meral Beksac, Cyrille Hulin, Elisabetta Antonioli, Xavier Leleu, Silvia Mangiacavalli, Aurore Perrot, Michele Cavo, Angelo Belotti, Annemiek Broijl, Francesca Gay, Roberto Mina, Inger S. Nijhof, Niels W.C.J. van de Donk, Eirini Katodritou, Fredrik Schjesvold, Anna Sureda Balari, Laura Rosiñol Dachs, Michel Delforge, Wilfried Roeloffzen, Christoph Driessen, Annette Vangsted, Hermann Einsele, Andrew Spencer, Roman Hajek, Artur Jurczyszyn, Sarah Lonergan, Yanfang Liu, Jianping Wang, Emilie M.J. van Brummelen, Veronique Vanquickelberghe, Anna Sitthi-Amorn, Carla J. de Boer, Robin Carson, Eva G. Katz, Katharine S. Gries, Jiaqi Song, Kai Fai Ho, Paula Rodríguez-Otero, Joan Bladé, Philippe Moreau
Journal: Blood
Blood (2024) 144 (Supplement 1): 2000.
https://doi.org/10.1182/blood-2024-201630
Published: 2024
Journal Articles

First-in-Human Phase 1 Study of SAR442257 in Patients with Relapsed/Refractory Multiple Myeloma and Non-Hodgkin Lymphoma

Fredrik Schjesvold, Tomas Jelinek, Kamila Polgarova, Ludek Pour, Sung-Soo Yoon, Won Seog Kim, Alexander Fosså, Jesús F. San-Miguel, Miguel Canales, Paula Rodríguez-Otero, Albert Oriol, Javier de la Rubia, Joaquín Martínez-Lopez, Sonia González De Villambrosia, Prashant Kapoor, Ola Landgren, James Edward Hoffman, Noopur Raje, Hongfang Wang, Kunal Jhunjhunwala, Liang Zhao, Zhini Wang, Mony Morisse, Helgi Van de Velde, Nitya Nathwani
Journal: Blood
Blood (2024) 144 (Supplement 1): 1992.
https://doi.org/10.1182/blood-2024-204614
Published: 2024
Journal Articles

Circulating Tumor Cells As a Biomarker to Identify High-Risk Transplant Eligible Myeloma Patients Treated with Bortezomib, Lenalidomide and Dexamethasone with or without Daratumumab during Induction/Consolidation, and Lenalidomide with or without Daratumumab during Maintenance: Results from the Perseus Study

Luca Bertamini, Cathelijne Fokkema, Paula Rodríguez-Otero, Mark van Duin, Niels W.C.J. Van De Donk, Mattia D'Agostino, Evangelos Terpos, Diego Vieyra, Ricardo M. Attar, Anna Sitthi-Amorn, Robin Carson, Michel Delforge, Christoph Driessen, Roman Hajek, Mario Boccadoro, Hermann Einsele, Annette Vangsted, Vincent H.J. Van Der Velden, Fredrik Schjesvold, Artur Jurczyszyn, Meral Beksac, Andrew Spencer, Annemiek Broijl, Tom Cupedo, Philippe Moreau, Pieter Sonneveld
Journal: Blood
Blood (2024) 144 (Supplement 1): 487.
https://doi.org/10.1182/blood-2024-199550
Published: 2024
Journal Articles

Identification and Evaluation of Novel Sdab-Based CAR-T Cells Against BCMA with Improved Therapeutic Efficacy for Multiple Myeloma

Vianca Ibarra-Garcia, Eva Molina, Franco Bernasconi-Bisio, Federica Rochira, Saray Rodríguez Diaz, Rebeca Martínez Turrillas, Paula Rodriguez-Marquez, Patricia Jauregui, Lucia Vanrell, Sara Villar, Paula Rodríguez-Otero, Juan J Lasarte, Juan Roberto Rodriguez-Madoz, Felipe Prosper, Antonio Pineda-Lucena
Journal: Blood
Blood (2024) 144 (Supplement 1): 7155.
https://doi.org/10.1182/blood-2024-208103
Published: 2024
Journal Articles

Delayed Neurotoxicity after CAR-T in Multiple Myeloma: Results from a Global IMWG Registry

Anupama Deepa Kumar, Suheil Albert Atallah-Yunes, Sridevi Rajeeve, Ahmed Abdelhak, Hamza Hashmi, Andre Corraes, Myo Htut, Paula Rodriguez-Otero, Ricardo D. Parrondo, Saurabh Chhabra, K. Martin Kortüm, Lukas Scheller, Sofie-Katrin Kadel, Hermann Einsele, Niels W.C.J. van de Donk, Jana Mihalyova, Roman Hajek, Joaquin Martinez Lopez, Noa Biran, Carlos Fernández de Larrea, Ingerid Weum Abrahamsen, Szu-Ying Chen, Melissa Ng, Bonell Patino Escobar, Simon J Harrison, Caitlin Costello, Isadora Matos, Edvan Crusoe, Luciano J. Costa, Arun P Wiita, Sasha Gupta, Thomas Martin, Yi Lin, Ajai Chari
Journal: Blood
Blood (2024) 144 (Supplement 1): 4758.
https://doi.org/10.1182/blood-2024-201783
Published: 2024
Journal Articles

Higher Teclistamab Step-up Dosing in Patients with Relapsed or Refractory Multiple Myeloma (RRMM): Results from the Majestec-1 Trial

Jeffrey V Matous, Niels W.C.J. van de Donk, Albert Oriol, Alfred L. Garfall, Paula Rodríguez-Otero, Thomas Chalopin, Laura Rosinol Dachs, Katarina Uttervall, Maria- Victoria Mateos, Danielle Trancucci, Natalia Quijano Cardé, Caroline Hodin, Tara Stephenson, Athena Zuppa, Katherine Chastain, Lionel Karlin
Journal: Blood
Blood (2024) 144 (Supplement 1): 4749.
https://doi.org/10.1182/blood-2024-204007
Published: 2024
Journal Articles

To be or Not to be? Exploring the Monitoring of Direct Oral Anticoagulants (DOACs) in Routine Clinical Practice

Clara Martínez, Balma Fernandez, Isabel Munuera, Julia Morell, Mireia Mico, Paula Rodriguez-Otero, Marcos Rivada, Cristina Soler, Sonia Martí, Soraya Palao, Claudia Gomez, Pedro Mirete, Juan Ramón De Moya, Edelmira Martí, Daniela Andrea Morello, Carlos Solano
Journal: Blood
Blood (2024) 144 (Supplement 1): 1258.
https://doi.org/10.1182/blood-2024-210888
Published: 2024
Journal Articles

Multiomic Characterization of Clonotypic B Cells in Patients with Monoclonal Gammopathies

Carmen Gonzalez, Camila Guerrero, Juan-José Garcés, Alejandro Medina, Noemi Puig, Maria Teresa Cedena Romero, Diego Alignani, Sarai Sarvide, Paula Aguirre-Ruiz, Jose Maria Lamo-Espinosa, Felipe Prosper, Paula Rodríguez-Otero, Jose A. Martinez-Climent, Aldo Roccaro, Antonio Sacco, Mario Nuvolone, Giovanni O. Palladini, Laura Rosiñol Dachs, Ramon García-Sanz, Joaquín Martínez-Lopez, Juan-Jose Lahuerta Palacios, Maria-Victoria Mateos, Joan Bladé, Jesús F. San-Miguel, Bruno Paiva
Journal: Blood
Blood (2024) 144 (Supplement 1): 1879.
https://doi.org/10.1182/blood-2024-201435
Published: 2024
Journal Articles

First Results from the Dose Escalation Part of the Phase 1 Study of KTX1001, an Oral, First-in-Class, Potent Inhibitor of MMSET/NSD2 for Relapsed/Refractory Multiple Myeloma (RRMM)

Pierre Bories, Cristina Gasparetto, David Dingli, Sagar Lonial, Saad Z. Usmani, Jesus G Berdeja, Alfred Chung, Aimaz Afrough, Laura Rosiñol, Andrew J. Yee, Suzanne Trudel, David S. Siegel, Paula Rodríguez-Otero, Soo Bang, Terry Connolly, Chad A. Lewis, Erin Flynt, Julie Vazquez, Sanjana U. Miskin, Benjamin Winograd, Maria-Victoria Mateos, Cyrille Touzeau, Vivek Roy
Journal: Blood
Blood (2024) 144 (Supplement 1): 3370.
https://doi.org/10.1182/blood-2024-199174
Published: 2024
Journal Articles

Molecular Mechanisms Promoting Long-Term Cytopenia after BCMA CAR-T Therapy in Multiple Myeloma

Maria Luisa Palacios-Berraquero, Paula Rodriguez-Marquez, Maria Erendira Calleja-Cervantes, Nerea Berastegui, Aintzane Zabaleta, Leire Burgos, Diego Alignani, Patxi San-Martin, Amaia Vilas-Zornoza, Saray Rodríguez Diaz, Susana Inogés, Ascensión López-Díaz De Cerio, Sofia Huerga, Luis-Esteban Tamariz-Amador, Jose J. Rifon, Ana Alfonso Pierola, Juan J Lasarte, Bruno Paiva, Mikel Hernaez, Paula Rodríguez-Otero, Jesús F. San-Miguel, Teresa Ezponda, Juan Roberto Rodriguez-Madoz, Felipe Prosper
Journal: Blood
Blood (2024) 144 (Supplement 1): 4798.
https://doi.org/10.1182/blood-2024-207990
Published: 2024