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ERIC SMITH
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Journal Articles

Live-cell pick-seq (LiP-Seq): Interrogating ultra-rare Mantle Cell Lymphoma MRD after CD19-targeted CAR T-cell therapy

Free
Ran Xu, Gongwei Wu, Siobhan Rice, Jenalyn Weekes, Yifei Gao, Ajit Nirmal, Huiyun Liu, Zoe Ciantra, Qingyu Luo, Amanda Fortune, Karley Whalen, Abner Louissaint, Joshua Nordberg, Jia-Ren Lin, Michael Hemann, Scott Manalis, Philippe Armand, Eric Smith, Caron Jacobson, Mark Murakami, Peter Sorger, David Weinstock, Li Song, Andrew Lane
Journal: Blood
Blood (2025) 146 (Supplement 1): 940.
https://doi.org/10.1182/blood-2025-940
Published: 2025
Journal Articles

Spatial proteomics of the bone marrow reveals distinct Tumor–Immune niches in smoldering and relapsed myeloma and their remodeling in response to bispecific antibody and CAR-T therapy

Free
David Cordas Dos Santos, Kane Foster, Daniel Heilpern-Mallory, Sophia Schroeder, Yoshinobu Konishi, Maria-Theresa Silverio, Jacqueline Perry, Sophie Magidson, Diego Vieyra, Rocio Montes De Oca, Daniel Zangrando, Nina Lane, Adam Sperling, Eric Smith, Jacob Laubach, Elizabeth O'Donnell, Nikhil Munshi, Kenneth Anderson, Shonali Midha, Gad Getz, Omar Nadeem, Irene Ghobrial
Journal: Blood
Blood (2025) 146 (Supplement 1): 3921.
https://doi.org/10.1182/blood-2025-3921
Published: 2025
Journal Articles

Interim analysis of safety and efficacy in a Phase 2 study of MB-105, a CD5.CAR T therapy for patients with relapsed/refractory T cell lymphoma

Free
Swami Iyer, Salvia Jain, Aaron Goodman, Julie Vose, Eric Mou, LaQuisa Hill, Steven Horwitz, Natalie Grover, Anne Beaven, Aleksandr Lazaryan, Malcolm Brenner, Sarah Hein, Federica Giordano, Eric Smith, Robert Michel, Ah-Reum Jeong, Michael Tees, Andy Chen, Shashank Cingam, Maksim Mamonkin, Alice Bexon
Journal: Blood
Blood (2025) 146 (Supplement 1): 775.
https://doi.org/10.1182/blood-2025-775
Published: 2025
Journal Articles

Reprogramming CAR-NK cells with IL-7/IL-7Rα to amplify STAT1 signaling and activate bystander T cells for enhanced immunotherapy

Free
Andreia Maia, Mubin Tarannum, Sara Piccinelli, Eric de Sousa, Fabian Göllner, Tereza Kochs, Caroline Fahey, Grace Birch, Mila Stanojevic, Maily Nguyen, Eden Bobilev, Alaa Ali, Edward Briercheck, Roman Shapiro, Eric Smith, David A. Barbie, John Koreth, Robert Soiffer, Catherine Wu, Jerome Ritz, Rizwan Romee
Journal: Blood
Blood (2025) 146 (Supplement 1): 4129.
https://doi.org/10.1182/blood-2025-4129
Published: 2025
Journal Articles

Intravenously administered LV-169 delivers a functional BCMA-CAR transgene to niche-resident T cells and leads to elimination of disseminated myeloma in MHC-deficient NSG mice

Free
Stephen Russell, Gopal Naik Nenavath, Nandakumar Packiriswamy, Timothy Carey, Md Yeashin Gazi, Aaron Hawkes, Collin Gwilt, Chia-Hsuan Chin, Christian Kinney, Hamid Salimi, Thipparat Suwanmanee, Darren Phung, Karina Krotova, Rianna Vandergaast, Kartika Venugopal, Edward Briercheck, Eric Smith, Yi Lin, Kah-Whye Peng
Journal: Blood
Blood (2025) 146 (Supplement 1): 5896.
https://doi.org/10.1182/blood-2025-5896
Published: 2025
Journal Articles

Identification of persister cells and evolution of tumor clones during immunotherapy and at minimal residual disease timepoints decoded by single-cell whole-genome sequencing in multiple myeloma

Free
Rosa Toenges, Jean-Baptiste Alberge, Tomoki Iemura, Francesco Corrado, Nayda Bidikian, David Cordas Dos Santos, Ankit Dutta, Romanos Sklavenitis-Pistofidis, Subear Hussein, Carlson Ketcham, Sophie Magidson, Shonali Midha, Elizabeth O'Donnell, Adam Sperling, Jacob Laubach, Kenneth Anderson, Eric Smith, Nikhil Munshi, Omar Nadeem, Gad Getz, Irene Ghobrial
Journal: Blood
Blood (2025) 146 (Supplement 1): 3930.
https://doi.org/10.1182/blood-2025-3930
Published: 2025
Journal Articles

Tumor burden quantified by soluble B-cell maturation antigen and metabolic tumor volume determines myeloma CAR-T outcomes

Available to Purchase
Ciara L. Freeman, Jerald Noble, Meghan Menges, Ricardo Villanueva, Justyn Y. Nakashima, Nicholas B. Figura, Rolf Petter Tonseth, Dietrich Werner Idiaquez, Lawrence Skelson, Eric Smith, Julieta Abraham-Miranda, Salvatore Corallo, Gabriel De Avila, Omar A. Castaneda Puglianini, Hien Liu, Melissa Alsina, Taiga Nishihori, Kenneth H. Shain, Rachid Baz, Brandon Blue, Ariel Grajales-Cruz, John M. Koomen, Reginald M. Atkins, Doris K. Hansen, Ariosto S. Silva, Jongphil Kim, Yoganand Balagurunathan, Frederick L. Locke
Journal: Blood
Blood (2025) 145 (15): 1645–1657.
https://doi.org/10.1182/blood.2024024965
Published: 2025
Includes: Supplemental data
Journal Articles

Genomic Determinants of Resistance to Anti-BCMA Chimeric Antigen Receptor T-Cell (CART) Therapies in Patients with Relapsed/Refractory Multiple Myeloma

Free
Francesco Maura, Ciara Louise Freeman, Holly Lee, Kylee H Maclachlan, Michael Durante, Bachisio Ziccheddu, Meghan Menges, Benjamin Diamond, Marios Papadimitriou, Ariosto Siqueira Silva, Praneeth Reddy Sudalagunta, Noemie Leblay, Sungwoo Ahn, Ethan Fuller, Edward Briercheck, Phaedra Agius, Doris K. Hansen, Xiaofei Song, Xiaohong Zhao, Mark B. Meads, Jamie Teer, Ross S Firestone, Juan-Jose Garces, Tomas Jelinek, Rachid Baz, Melissa Alsina, Anusuyam Ramasubramanian, Eric Smith, Sergio Giralt, Sham Mailankody, Paola Neri, Saad Z. Usmani, Frederick Locke, Nizar J. Bahlis, Ola Landgren, Kenneth H. Shain
Journal: Blood
Blood (2024) 144 (Supplement 1): 247.
https://doi.org/10.1182/blood-2024-201288
Published: 2024
Journal Articles

Characterization of Linvoseltamab's BCMA Binding Epitope and Efficacy Against BCMA Mutations in Relapsed/Refractory Multiple Myeloma

Free
Ken Lee, Yi Zhou, Matthew Franklin, Erica Ullman, Aynur Hermann, Glenn S. Kroog, Anita Boyapati, Karen Rodriguez Lorenc, Eric Smith, John Lin, William Olson, Leonardo Andres Sirulnik, Kara Olson
Journal: Blood
Blood (2024) 144 (Supplement 1): 3265.
https://doi.org/10.1182/blood-2024-208776
Published: 2024
Journal Articles

A CD38xCD28 Costimulatory Bispecific Antibody Demonstrates Potent Preclinical Combinatorial Activity with a BCMAxCD3 T Cell-Engager

Free
Kara Olson, David DiLillo, Olga Sineshchekova, Katja Mohrs, Craig McCarthy, Hassan Ahmed, Sahar Rizvi, Steven Quatela, Elizabeth Navarro, Cuiyan Lin, Amanda Dorvilliers, Glenn S. Kroog, Karen Rodriguez Lorenc, Erica Ullman, Aynur Hermann, Eric Smith, Jessica Kirshner, William Olson, John Lin
Journal: Blood
Blood (2024) 144 (Supplement 1): 3283.
https://doi.org/10.1182/blood-2024-194830
Published: 2024
Journal Articles

Early Results of MT-401 (Zedenoleucel) in Post-Transplant MRD + aml Patients

Free
Mythili Koneru, Shukaib Arslan, Margarida Magalhaes Magalhaes-Silverman, Hongtao Liu, Nelli Bejanyan, Antonio Di Stasi, Robin McCallum, Silvia Quintero, Gerald Garrett, Karrie Wang, Eric Smith, Tara Shahim, Lina Hoang, Jeannette Crisostomo, Anna Wilga-Savitski, Jennifer Pickering, Laura Angelo, Anastasiya Smith, Juan F. Vera, Betul Oran, Jingmei Hsu
Journal: Blood
Blood (2022) 140 (Supplement 1): 12718–12719.
https://doi.org/10.1182/blood-2022-155602
Published: 2022
Journal Articles

REGN5458, a Bispecific BCMAxCD3 T Cell Engaging Antibody, Demonstrates Robust In Vitro and In Vivo Anti-Tumor Efficacy in Multiple Myeloma Models, Comparable to That of BCMA CAR T Cells

Free
David J Dilillo, PhD, Kara Olson, MS, Katja Mohrs, T. Craig Meagher, PhD, Kevin Bray, PhD, Olga Sineshchekova, Thomas Startz, Marc Retter, PhD, Stephen Godin, PhD, Frank Delfino, PhD, John Lin, PhD, Eric Smith, PhD, Olin Gavin Thurston, PhD, Jessica R. Kirshner, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1944.
https://doi.org/10.1182/blood-2018-99-112500
Published: 2018
Journal Articles

CD20xCD3 Bispecific Fully Human Antibody Induces Potent Anti-Tumor Activity Against CD20-Expressing Tumors in Immune Competent Mice Humanized for CD20 and CD3

Free
Bindu Varghese, PhD, Jayanthi Menon, Luis Rodriguez, Kara Olson, Pamela Krueger, Tammy Huang, PhD, Eric Smith, PhD, Gavin Thurston, PhD, Jessica R. Kirshner, PhD
Journal: Blood
Blood (2015) 126 (23): 818.
https://doi.org/10.1182/blood.V126.23.818.818
Published: 2015
Journal Articles

A Novel CD20xCD3 Bispecific Fully Human Antibody Induces Potent Anti-Tumor Effects Against B Cell Lymphoma in Mice

Free
Bindu Varghese, PhD, Jayanthi Menon, Luis Rodriguez, Lauric Haber, Kara Olson, Paurene Duramad, PhD, Adelekan Oyejide, Eric Smith, PhD, Gavin Thurston, PhD, Jessica Kirshner, PhD
Journal: Blood
Blood (2014) 124 (21): 4501.
https://doi.org/10.1182/blood.V124.21.4501.4501
Published: 2014
Journal Articles

Treatment of Newly Diagnosed, Inner-City Multiple Myeloma Patients with Low-Dose Thalidomide in Combination with Dexamethasone and Zoledronate: A Phase II Trial.

Free
Uwe Klueppelberg, MD, PhD, Iuliana Shapira, MD, Eric Smith, PhD, Marc Braunstein, BS, David Kahn, MD, Yury Pertsovsky, Olcay Batuman, MD
Journal: Blood
Blood (2005) 106 (11): 5180.
https://doi.org/10.1182/blood.V106.11.5180.5180
Published: 2005
Journal Articles

First-Line Treatment of Multiple Myeloma with a Combination of Thalidomide, Dexamethasone, and Zoledronate (TDZ) in an Inner-City Population with High HIV Prevalence.

Free
Uwe Klueppelberg, MD PhD, Eric Smith, PhD, Laurie Chen, MD, Chona M. Aloba, MD, Iuliana Shapira, MD, Mehdi M. Moezi, MD, Olcay Batuman, MD
Journal: Blood
Blood (2004) 104 (11): 4932.
https://doi.org/10.1182/blood.V104.11.4932.4932
Published: 2004
Journal Articles

Evidence for Clonality in Circulating Endothelial Progenitor Cells in Multiple Myeloma.

Free
Tayfun Ozcelik, MD, Varsha Vakil, Eric Smith, PhD, Marc Braunstein, Justin Maroney, Uwe Klueppelberg, MD PhD, Sevgi Bagislar, Cemaliye Akyerli, Olcay Batuman, MD
Journal: Blood
Blood (2004) 104 (11): 2357.
https://doi.org/10.1182/blood.V104.11.2357.2357
Published: 2004
Journal Articles

Metastatic Acropachy in Lymphatic Leukemia

Free
ROWLAND J. CALVERT, ERIC SMITH
Journal: Blood
Blood (1955) 10 (5): 545–549.
https://doi.org/10.1182/blood.V10.5.545.545
Published: 1955