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Issue Archive

Volume 132, Issue 19
November 8 2018
Issue Cover

Table of Contents

BLOOD COMMENTARIES

CLINICAL TRIALS AND OBSERVATIONS
Chemotherapy-free induction in MCL: ready for prime time?
Clinical Trials & Observations
Kami Maddocks
View Articletitled, Chemotherapy-free induction in MCL: ready for prime time?
PLATELETS AND THROMBOPOIESIS
EPHB2 regulates platelet activation
Michael C. Berndt,Robert K. Andrews
View Articletitled, EPHB2 regulates platelet activation
Red Cells, Iron, and Erythropoiesis
Erythrocytes and erythroblasts give up iron
Tomas Ganz
View Articletitled, Erythrocytes and erythroblasts give up iron
TRANSPLANTATION
HLH: watch and wait, or act and cure?
Kenneth L. McClain,Caridad A. Martinez
View Articletitled, HLH: watch and wait, or <em>act and cure</em>?
THROMBOSIS AND HEMOSTASIS
One over PAR or one under PAR: vive la différence
Jorge Di Paola,Paul F. Bray
View Articletitled, One over PAR or one under PAR: vive la différence

PERSPECTIVE

Testing and monitoring direct oral anticoagulants
Jean M. Connors
View Articletitled, Testing and monitoring direct oral anticoagulants

CLINICAL TRIALS AND OBSERVATIONS

Five-year follow-up of lenalidomide plus rituximab as initial treatment of mantle cell lymphoma
Clinical Trials & Observations
Jia Ruan,Peter Martin,Paul Christos,Leandro Cerchietti,Wayne Tam,Bijal Shah,Stephen J. Schuster,Amelyn Rodriguez,David Hyman,Maria Nieves Calvo-Vidal,Sonali M. Smith,Jakub Svoboda,Richard R. Furman,Morton Coleman,John P. Leonard
View Articletitled, Five-year follow-up of lenalidomide plus rituximab as initial treatment of mantle cell lymphoma

LYMPHOID NEOPLASIA

PRMT5 interacts with the BCL6 oncoprotein and is required for germinal center formation and lymphoma cell survival
Xiaoqing Lu,Tharu M. Fernando,Chen Lossos,Nevin Yusufova,Fan Liu,Lorena Fontán,Matthew Durant,Huimin Geng,Jacob Melnick,Yuan Luo,Francisco Vega,Vincent Moy,Giorgio Inghirami,Stephen Nimer,Ari M. Melnick,Izidore S. Lossos
View Articletitled, PRMT5 interacts with the BCL6 oncoprotein and is required for germinal center formation and lymphoma cell survival
Supplemental data
Genome-wide association study implicates immune dysfunction in the development of Hodgkin lymphoma
Amit Sud,Hauke Thomsen,Giulia Orlando,Asta Försti,Philip J. Law,Peter Broderick,Rosie Cooke,Fadi Hariri,Tomi Pastinen,Douglas F. Easton,Paul D. P. Pharoah,Alison M. Dunning,Julian Peto,Federico Canzian,Rosalind Eeles,ZSofia Kote-Jarai,Kenneth Muir,Nora Pashayan,Daniele Campa,the PRACTICAL Consortium,Per Hoffmann,Markus M. Nöthen,Karl-Heinz Jöckel,Elke Pogge von Strandmann,Anthony J. Swerdlow,Andreas Engert,Nick Orr,Kari Hemminki,Richard S. Houlston
View Articletitled, Genome-wide association study implicates immune dysfunction in the development of Hodgkin lymphoma
Supplemental data

MYELOID NEOPLASIA

Bone marrow–specific loss of ABI1 induces myeloproliferative neoplasm with features resembling human myelofibrosis
Anna Chorzalska,John Morgan,Nagib Ahsan,Diana O. Treaba,Adam J. Olszewski,Max Petersen,Nathan Kingston,Yan Cheng,Kara Lombardo,Christoph Schorl,Xiaoqing Yu,Roberta Zini,Annalisa Pacilli,Alexander Tepper,Jillian Coburn,Anita Hryniewicz-Jankowska,Ting C. Zhao,Elena Oancea,John L. Reagan,Olin Liang,Leszek Kotula,Peter J. Quesenberry,Philip A. Gruppuso,Rossella Manfredini,Alessandro Maria Vannucchi,Patrycja M. Dubielecka
View Articletitled, Bone marrow–specific loss of <em>ABI1</em> induces myeloproliferative neoplasm with features resembling human myelofibrosis
Supplemental data

PLATELETS AND THROMBOPOIESIS

A mutation of the human EPHB2 gene leads to a major platelet functional defect
Eliane Berrou,Christelle Soukaseum,Rémi Favier,Frédéric Adam,Ziane Elaib,Alexandre Kauskot,Jean-Claude Bordet,Paola Ballerini,Stephane Loyau,Miao Feng,Karine Dias,Abbas Muheidli,Stephane Girault,Alan T. Nurden,Ernest Turro,Willem H. Ouwehand,Cécile V. Denis,Martine Jandrot-Perrus,Jean-Philippe Rosa,Paquita Nurden,Marijke Bryckaert
View Articletitled, A mutation of the human <em>EPHB2</em> gene leads to a major platelet functional defect
Supplemental data

RED CELLS, IRON, AND ERYTHROPOIESIS

Ferroportin deficiency in erythroid cells causes serum iron deficiency and promotes hemolysis due to oxidative stress
De-Liang Zhang,Manik C. Ghosh,Hayden Ollivierre,Yan Li,Tracey A. Rouault

There is a Blood Commentary on this article in this issue.

View Articletitled, Ferroportin deficiency in erythroid cells causes serum iron deficiency and promotes hemolysis due to oxidative stress
Supplemental data

TRANSPLANTATION

Treatment dilemmas in asymptomatic children with primary hemophagocytic lymphohistiocytosis
Giovanna Lucchini,Rebecca Marsh,Kimberly Gilmour,Austen Worth,Zohreh Nademi,Anupama Rao,Claire Booth,Persis Amrolia,Juliana Silva,Robert Chiesa,Robert Wynn,Kai Lehmberg,Itziar Astigarraga,Tayfun Güngör,Jan Stary,Despina Moshous,Marianne Ifversen,Daniel Zinn,Michael Jordan,Ashish Kumar,Takahiro Yasumi,Paul Veys,Kanchan Rao
View Articletitled, Treatment dilemmas in asymptomatic children with primary hemophagocytic lymphohistiocytosis
Supplemental data

LETTER TO BLOOD

Promising activity of nelfinavir-bortezomib-dexamethasone in proteasome inhibitor–refractory multiple myeloma
Clinical Trials & Observations
Christoph Driessen,Rouven Müller,Urban Novak,Nathan Cantoni,Daniel Betticher,Nicolas Mach,Axel Rüfer,Ulrich Mey,Panagiotis Samaras,Karin Ribi,Lenka Besse,Andrej Besse,Catherine Berset,Stephanie Rondeau,Hanne Hawle,Felicitas Hitz,Thomas Pabst,Thilo Zander
View Articletitled, Promising activity of nelfinavir-bortezomib-dexamethasone in proteasome inhibitor–refractory multiple myeloma
Supplemental data
Mutational landscape of myelodysplastic/myeloproliferative neoplasm–unclassifiable
Prithviraj Bose,Aziz Nazha,Rami S. Komrokji,Keyur P. Patel,Sherry A. Pierce,Najla Al-Ali,Andrew Sochacki,Aaron Shaver,Wencai Ma,Xiaoping Su,Naval G. Daver,Courtney D. DiNardo,Guillermo Garcia-Manero,Sanam Loghavi,Carlos Bueso-Ramos,Hagop M. Kantarjian,Mikkael A. Sekeres,Michael R. Savona,Jaroslaw P. Maciejewski,Srdan Verstovsek
View Articletitled, Mutational landscape of myelodysplastic/myeloproliferative neoplasm–unclassifiable
Supplemental data
Frequency of PAR4 Ala120Thr variant associated with platelet reactivity significantly varies across sub-Saharan African populations
Menikae K. Heenkenda,Tomas L. Lindahl,Abdimajid Osman
View Articletitled, Frequency of PAR4 Ala120Thr variant associated with platelet reactivity significantly varies across sub-Saharan African populations

BLOOD WORK

B & B: basophils and bleeding, an atypical case of acute promyelocytic leukemia
Benjamin Lebecque,Nicolas Lechevalier
View Articletitled, B &amp; B: basophils and bleeding, an atypical case of acute promyelocytic leukemia
All Issues

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