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Issue Archive

Volume 132, Issue 16
October 18 2018
Issue Cover

Table of Contents

BLOOD COMMENTARIES

IMMUNOBIOLOGY AND IMMUNOTHERAPY
TIGIT checkpoint inhibition for myeloma
Fotis Asimakopoulos
View Articletitled, TIGIT checkpoint inhibition for myeloma
Myeloma escape after stem cell transplantation is a consequence of T-cell exhaustion and is prevented by TIGIT blockade
Simone A. Minnie,Rachel D. Kuns,Kate H. Gartlan,Ping Zhang,Andrew N. Wilkinson,Luke Samson,Camille Guillerey,Christian Engwerda,Kelli P. A. MacDonald,Mark J. Smyth,Kate A. Markey,Slavica Vuckovic,Geoffrey R. Hill
View Articletitled, Myeloma escape after stem cell transplantation is a consequence of T-cell exhaustion and is prevented by TIGIT blockade
Supplemental data
Lymphoid Neoplasia
t(14;18)-positive B cells: is it seed or soil?
Elaine S. Jaffe,Leticia Quintanilla-Martinez
View Articletitled, t(14;18)-positive B cells: is it seed or soil?
Red Cells, Iron, and Erythropoiesis
Silent cerebral infarction: supply and demand
Charles T. Quinn
View Articletitled, Silent cerebral infarction: supply and demand

SPECIAL REPORT

Proton therapy for adults with mediastinal lymphomas: the International Lymphoma Radiation Oncology Group guidelines
Clinical Trials & Observations
Bouthaina Shbib Dabaja,Bradford S. Hoppe,John P. Plastaras,Wayne Newhauser,Katerina Rosolova,Stella Flampouri,Radhe Mohan,N. George Mikhaeel,Youlia Kirova,Lena Specht,Joachim Yahalom
View Articletitled, Proton therapy for adults with mediastinal lymphomas: the International Lymphoma Radiation Oncology Group guidelines
Supplemental data

REVIEW ARTICLE

Update on mantle cell lymphoma
Kami Maddocks
View Articletitled, Update on mantle cell lymphoma

HOW I TREAT

How I use molecular genetic tests to evaluate patients who have or may have myelodysplastic syndromes
Clinical Trials & Observations
David P. Steensma
View Articletitled, How I use molecular genetic tests to evaluate patients who have or may have myelodysplastic syndromes

CLINICAL TRIALS AND OBSERVATIONS

A phase 2 study of ruxolitinib in combination with azacitidine in patients with myelofibrosis
Clinical Trials & Observations
Lucia Masarova,Srdan Verstovsek,Juliana E. Hidalgo-Lopez,Naveen Pemmaraju,Prithviraj Bose,Zeev Estrov,Elias J. Jabbour,Farhad Ravandi-Kashani,Koichi Takahashi,Jorge E. Cortes,Jing Ning,Maro Ohanian,Yesid Alvarado,Lingsha Zhou,Sherry Pierce,Romany Gergis,Keyur P. Patel,Rajyalakshmi Luthra,Tapan M. Kadia,Courtney D. DiNardo,Gautam Borthakur,Kapil Bhalla,Guillermo Garcia-Manero,Carlos E. Bueso-Ramos,Hagop M. Kantarjian,Naval Daver
View Articletitled, A phase 2 study of ruxolitinib in combination with azacitidine in patients with myelofibrosis
Supplemental data

IMMUNOBIOLOGY AND IMMUNOTHERAPY

Myeloma escape after stem cell transplantation is a consequence of T-cell exhaustion and is prevented by TIGIT blockade
Simone A. Minnie,Rachel D. Kuns,Kate H. Gartlan,Ping Zhang,Andrew N. Wilkinson,Luke Samson,Camille Guillerey,Christian Engwerda,Kelli P. A. MacDonald,Mark J. Smyth,Kate A. Markey,Slavica Vuckovic,Geoffrey R. Hill
View Articletitled, Myeloma escape after stem cell transplantation is a consequence of T-cell exhaustion and is prevented by TIGIT blockade
Supplemental data
TIGIT immune checkpoint blockade restores CD8+ T-cell immunity against multiple myeloma
Brief Report
Camille Guillerey,Heidi Harjunpää,Nadège Carrié,Sahar Kassem,Tricia Teo,Kim Miles,Sophie Krumeich,Marianne Weulersse,Marine Cuisinier,Kimberley Stannard,Yuan Yu,Simone A. Minnie,Geoffrey R. Hill,William C. Dougall,Hervé Avet-Loiseau,Michele W. L. Teng,Kyohei Nakamura,Ludovic Martinet,Mark J. Smyth
View Articletitled, TIGIT immune checkpoint blockade restores CD8<sup>+</sup> T-cell immunity against multiple myeloma

LYMPHOID NEOPLASIA

Duodenal-type and nodal follicular lymphomas differ by their immune microenvironment rather than their mutation profiles
Clinical Trials & Observations
Johannes C. Hellmuth,Abner Louissaint, Jr,Monika Szczepanowski,Sarah Haebe,Alessandro Pastore,Stefan Alig,Annette M. Staiger,Sylvia Hartmann,Robert Kridel,Matthew D. Ducar,Peter Koch,Martin Dreyling,Martin-Leo Hansmann,German Ott,Andreas Rosenwald,Randy D. Gascoyne,David M. Weinstock,Wolfgang Hiddemann,Wolfram Klapper,Oliver Weigert
View Articletitled, Duodenal-type and nodal follicular lymphomas differ by their immune microenvironment rather than their mutation profiles
Supplemental data

MYELOID NEOPLASIA

Measurable residual disease monitoring by NGS before allogeneic hematopoietic cell transplantation in AML
Clinical Trials & Observations
Felicitas Thol,Razif Gabdoulline,Alessandro Liebich,Piroska Klement,Johannes Schiller,Christian Kandziora,Lothar Hambach,Michael Stadler,Christian Koenecke,Madita Flintrop,Mira Pankratz,Martin Wichmann,Blerina Neziri,Konstantin Büttner,Bennet Heida,Sabrina Klesse,Anuhar Chaturvedi,Arnold Kloos,Gudrun Göhring,Brigitte Schlegelberger,Verena I. Gaidzik,Lars Bullinger,Walter Fiedler,Albert Heim,Iyas Hamwi,Matthias Eder,Jürgen Krauter,Richard F. Schlenk,Peter Paschka,Konstanze Döhner,Hartmut Döhner,Arnold Ganser,Michael Heuser
View Articletitled, Measurable residual disease monitoring by NGS before allogeneic hematopoietic cell transplantation in AML
Supplemental data

RED CELLS, IRON, AND ERYTHROPOIESIS

Silent infarcts in sickle cell disease occur in the border zone region and are associated with low cerebral blood flow
CME
Andria L. Ford,Dustin K. Ragan,Slim Fellah,Michael M. Binkley,Melanie E. Fields,Kristin P. Guilliams,Hongyu An,Lori C. Jordan,Robert C. McKinstry,Jin-Moo Lee,Michael R. DeBaun
View Articletitled, Silent infarcts in sickle cell disease occur in the border zone region and are associated with low cerebral blood flow

BLOOD WORK

Walking on myeloma
Bart Barlogie,Joshua Richter
View Articletitled, Walking on myeloma
Unusual location of a follicular lymphoma with features of pediatric-type follicular lymphoma
Christina Kanaan,Barbara Burroni
View Articletitled, Unusual location of a follicular lymphoma with features of pediatric-type follicular lymphoma

ERRATUM

Malard F, Labopin M, Chevallier P, et al. Larger number of invariant natural killer T cells in PBSC allografts correlates with improved GVHD-free and progression-free survival. Blood. 2016;127(14):1828-1835.
View Articletitled, Malard F, Labopin M, Chevallier P, et al. Larger number of invariant natural killer T cells in PBSC allografts correlates with improved GVHD-free and progression-free survival. <em>Blood.</em> 2016;127(14):1828-1835.

CONTINUING MEDICAL EDUCATION (CME) QUESTIONS

Location of silent cerebral infarcts in SIT
CME
View Articletitled, Location of silent cerebral infarcts in SIT
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