Skip to Main Content

Advertisement

Umbrella Alt Text
Cart
header search
Search
Skip Nav Destination

Issue Archive

Volume 115, Issue 10
March 11 2010
Issue Cover

Table of Contents

INSIDE BLOOD

CLINICAL TRIALS
More force or more smart?
Pieter Sonneveld
View Articletitled, More force or more smart?
CLINICAL TRIALS
Transplantation for CML: 2010
Richard T. Maziarz
View Articletitled, Transplantation for CML: 2010
HEMATOPOIESIS & STEM CELLS
CCR7/CCR9: knockin' on the thymus door
Naomi Taylor
View Articletitled, CCR7/CCR9: knockin' on the thymus door
THROMBOSIS & HEMOSTASIS
PAI-1: cardiac friend or foe?
Lindsey A. Miles,Robert J. Parmer
View Articletitled, PAI-1: cardiac friend or foe?
TRANSFUSION MEDICINE
Identification of the HNA-3a antigen
Christopher C. Silliman,David Stroncek
View Articletitled, Identification of the HNA-3a antigen

REVIEW ARTICLES

Graft-versus-host disease: regulation by microbe-associated molecules and innate immune receptors
Olaf Penack,Ernst Holler,Marcel R. M. van den Brink
View Articletitled, Graft-versus-host disease: regulation by microbe-associated molecules and innate immune receptors

CLINICAL TRIALS AND OBSERVATIONS

Melphalan 200 mg/m2 versus melphalan 100 mg/m2 in newly diagnosed myeloma patients: a prospective, multicenter phase 3 study
Clinical Trials & Observations
Antonio Palumbo,Sara Bringhen,Benedetto Bruno,Antonietta Pia Falcone,Anna Marina Liberati,Mariella Grasso,Roberto Ria,Francesco Pisani,Clotilde Cangialosi,Tommaso Caravita,Anna Levi,Giovanna Meloni,Andrea Nozza,Patrizia Pregno,Attilio Gabbas,Vincenzo Callea,Manuela Rizzo,Luciana Annino,Valerio De Stefano,Pellegrino Musto,Ileana Baldi,Federica Cavallo,Maria Teresa Petrucci,Massimo Massaia,Mario Boccadoro
View Articletitled, Melphalan 200 mg/m<sup>2</sup> versus melphalan 100 mg/m<sup>2</sup> in newly diagnosed myeloma patients: a prospective, multicenter phase 3 study
Allogeneic hematopoietic stem cell transplantation (allo SCT) for chronic myeloid leukemia in the imatinib era: evaluation of its impact within a subgroup of the randomized German CML Study IV
Clinical Trials & Observations
Susanne Saussele,Michael Lauseker,Alois Gratwohl,Dietrich W. Beelen,Donald Bunjes,Rainer Schwerdtfeger,Hans-Jochem Kolb,Anthony D. Ho,Christiane Falge,Ernst Holler,Günter Schlimok,Axel R. Zander,Renate Arnold,Lothar Kanz,Robert Dengler,Claudia Haferlach,Brigitte Schlegelberger,Markus Pfirrmann,Martin C. Müller,Susanne Schnittger,Armin Leitner,Nadine Pletsch,Andreas Hochhaus,Joerg Hasford,Rüdiger Hehlmann,for the German CML Study Group
View Articletitled, Allogeneic hematopoietic stem cell transplantation (allo SCT) for chronic myeloid leukemia in the imatinib era: evaluation of its impact within a subgroup of the randomized German CML Study IV
Supplemental data
Overview on practices in thalassemia intermedia management aiming for lowering complication rates across a region of endemicity: the OPTIMAL CARE study
Clinical Trials & Observations
Ali T. Taher,Khaled M. Musallam,Mehran Karimi,Amal El-Beshlawy,Khawla Belhoul,Shahina Daar,Mohamed-SalahEldin Saned,Abdul-Hamid El-Chafic,Maria R. Fasulo,Maria D. Cappellini
View Articletitled, Overview on practices in thalassemia intermedia management aiming for lowering complication rates across a region of endemicity: the OPTIMAL CARE study
Very long-term eradication of minimal residual disease in patients with hairy cell leukemia after a single course of cladribine
Brief Report
Darren S. Sigal,Robert Sharpe,Carol Burian,Alan Saven
View Articletitled, Very long-term eradication of minimal residual disease in patients with hairy cell leukemia after a single course of cladribine

HEMATOPOIESIS AND STEM CELLS

CCR7 and CCR9 together recruit hematopoietic progenitors to the adult thymus
Daniel A. Zlotoff,Arivazhagan Sambandam,Theodore D. Logan,J. Jeremiah Bell,Benjamin A. Schwarz,Avinash Bhandoola
View Articletitled, CCR7 and CCR9 together recruit hematopoietic progenitors to the adult thymus
Supplemental data
CC chemokine receptor 7 and 9 double-deficient hematopoietic progenitors are severely impaired in seeding the adult thymus
Andreas Krueger,Stefanie Willenzon,Marcin Łyszkiewicz,Elisabeth Kremmer,Reinhold Förster
View Articletitled, CC chemokine receptor 7 and 9 double-deficient hematopoietic progenitors are severely impaired in seeding the adult thymus
Supplemental data
Intrathymic transplantation of bone marrow–derived progenitors provides long-term thymopoiesis
Rita Vicente,Oumeya Adjali,Chantal Jacquet,Valérie S. Zimmermann,Naomi Taylor
View Articletitled, Intrathymic transplantation of bone marrow–derived progenitors provides long-term thymopoiesis
Supplemental data

IMMUNOBIOLOGY

TAK1 targeting by glucocorticoids determines JNK and IκB regulation in Toll-like receptor–stimulated macrophages
Sandip Bhattacharyya,Christine K. Ratajczak,Sherri K. Vogt,Crystal Kelley,Marco Colonna,Robert D. Schreiber,Louis J. Muglia
View Articletitled, TAK1 targeting by glucocorticoids determines JNK and IκB regulation in Toll-like receptor–stimulated macrophages
Supplemental data
Allogeneic T regulatory cell–mediated transplantation tolerance in adoptive therapy depends on dominant peripheral suppression and central tolerance
Dennis Adeegbe,Robert B. Levy,Thomas R. Malek
View Articletitled, Allogeneic T regulatory cell–mediated transplantation tolerance in adoptive therapy depends on dominant peripheral suppression and central tolerance
CD137 agonist antibody prevents cancer recurrence: contribution of CD137 on both hematopoietic and nonhematopoietic cells
Hidehiko Narazaki,Yuwen Zhu,Liqun Luo,Gefeng Zhu,Lieping Chen
View Articletitled, CD137 agonist antibody prevents cancer recurrence: contribution of CD137 on both hematopoietic and nonhematopoietic cells
Supplemental data
Plasmacytoid dendritic cell–derived type I interferon is crucial for the adjuvant activity of Toll-like receptor 7 agonists
Deepa Rajagopal,Carine Paturel,Yannis Morel,Satoshi Uematsu,Shizuo Akira,Sandra S. Diebold
View Articletitled, Plasmacytoid dendritic cell–derived type I interferon is crucial for the adjuvant activity of Toll-like receptor 7 agonists
Supplemental data
Skin-draining lymph nodes contain dermis-derived CD103− dendritic cells that constitutively produce retinoic acid and induce Foxp3+ regulatory T cells
Martin Guilliams,Karine Crozat,Sandrine Henri,Samira Tamoutounour,Pierre Grenot,Elisabeth Devilard,Béatrice de Bovis,Lena Alexopoulou,Marc Dalod,Bernard Malissen
View Articletitled, Skin-draining lymph nodes contain dermis-derived CD103<sup>−</sup> dendritic cells that constitutively produce retinoic acid and induce Foxp3<sup>+</sup> regulatory T cells
Supplemental data

MYELOID NEOPLASIA

Mutations of an E3 ubiquitin ligase c-Cbl but not TET2 mutations are pathogenic in juvenile myelomonocytic leukemia
Hideki Muramatsu,Hideki Makishima,Anna M. Jankowska,Heather Cazzolli,Christine O'Keefe,Nao Yoshida,Yinyan Xu,Nobuhiro Nishio,Asahito Hama,Hiroshi Yagasaki,Yoshiyuki Takahashi,Koji Kato,Atsushi Manabe,Seiji Kojima,Jaroslaw P. Maciejewski
View Articletitled, Mutations of an E3 ubiquitin ligase <em>c-Cbl</em> but not <em>TET2</em> mutations are pathogenic in juvenile myelomonocytic leukemia
Leukemia-initiating cells from some acute myeloid leukemia patients with mutated nucleophosmin reside in the CD34− fraction
David C. Taussig,Jacques Vargaftig,Farideh Miraki-Moud,Emmanuel Griessinger,Kirsty Sharrock,Tina Luke,Debra Lillington,Heather Oakervee,Jamie Cavenagh,Samir G. Agrawal,T. Andrew Lister,John G. Gribben,Dominique Bonnet
View Articletitled, Leukemia-initiating cells from some acute myeloid leukemia patients with mutated <em>nucleophosmin</em> reside in the CD34<sup>−</sup> fraction
Supplemental data
Acute erythroid leukemia: a reassessment using criteria refined in the 2008 WHO classification
Robert P. Hasserjian,Zhuang Zuo,Christine Garcia,Guilin Tang,Armen Kasyan,Rajyalakshmi Luthra,Lynne V. Abruzzo,Hagop M. Kantarjian,L. Jeffrey Medeiros,Sa A. Wang
View Articletitled, Acute erythroid leukemia: a reassessment using criteria refined in the 2008 WHO classification
Identification of DJ-1/PARK-7 as a determinant of stroma-dependent and TNF-α–induced apoptosis in MDS using mass spectrometry and phosphopeptide analysis
A. Mario Marcondes,Xiang Li,Ted A. Gooley,Brian Milless,H. Joachim Deeg
View Articletitled, Identification of DJ-1/PARK-7 as a determinant of stroma-dependent and TNF-α–induced apoptosis in MDS using mass spectrometry and phosphopeptide analysis
Supplemental data
Clonal analysis of TET2 and JAK2 mutations suggests that TET2 can be a late event in the progression of myeloproliferative neoplasms
Brief Report
Franz X. Schaub,Renate Looser,Sai Li,Hui Hao-Shen,Thomas Lehmann,Andre Tichelli,Radek C. Skoda
View Articletitled, Clonal analysis of <em>TET2</em> and <em>JAK2</em> mutations suggests that <em>TET2</em> can be a late event in the progression of myeloproliferative neoplasms
Supplemental data

PLATELETS AND THROMBOPOIESIS

Deletion of the p110β isoform of phosphoinositide 3-kinase in platelets reveals its central role in Akt activation and thrombus formation in vitro and in vivo
Brief Report
Valérie Martin,Julie Guillermet-Guibert,Gaétan Chicanne,Cendrine Cabou,Martine Jandrot-Perrus,Monique Plantavid,Bart Vanhaesebroeck,Bernard Payrastre,Marie-Pierre Gratacap
View Articletitled, Deletion of the p110β isoform of phosphoinositide 3-kinase in platelets reveals its central role in Akt activation and thrombus formation in vitro and in vivo
Supplemental data

RED CELLS, IRON, AND ERYTHROPOIESIS

Placenta growth factor in sickle cell disease: association with hemolysis and inflammation
Julia E. Brittain,Ben Hulkower,Susan K. Jones,Dell Strayhorn,Laura De Castro,Marilyn J. Telen,Eugene P. Orringer,Alan Hinderliter,Kenneth I. Ataga
View Articletitled, Placenta growth factor in sickle cell disease: association with hemolysis and inflammation
Membrane remodeling during reticulocyte maturation
Jing Liu,Xinhua Guo,Narla Mohandas,Joel A. Chasis,Xiuli An
View Articletitled, Membrane remodeling during reticulocyte maturation
Supplemental data
H4R3 methylation facilitates β-globin transcription by regulating histone acetyltransferase binding and H3 acetylation
Xingguo Li,Xin Hu,Bhavita Patel,Zhuo Zhou,Shermi Liang,River Ybarra,Yi Qiu,Gary Felsenfeld,Jörg Bungert,Suming Huang
View Articletitled, H4R3 methylation facilitates β<em>-globin</em> transcription by regulating histone acetyltransferase binding and H3 acetylation
Supplemental data

THROMBOSIS AND HEMOSTASIS

Plasminogen activator inhibitor-1 (PAI-1) is cardioprotective in mice by maintaining microvascular integrity and cardiac architecture
Zhi Xu,Francis J. Castellino,Victoria A. Ploplis
View Articletitled, Plasminogen activator inhibitor-1 (PAI-1) is cardioprotective in mice by maintaining microvascular integrity and cardiac architecture
Fibrinolytic cross-talk: a new mechanism for plasmin formation
Tiphaine Dejouvencel,Loïc Doeuvre,Romaric Lacroix,Laurent Plawinski,Françoise Dignat-George,H. Roger Lijnen,Eduardo Anglés-Cano
View Articletitled, Fibrinolytic cross-talk: a new mechanism for plasmin formation
Supplemental data
Prolonged activity of factor IX as a monomeric Fc fusion protein
Robert T. Peters,Susan C. Low,George D. Kamphaus,Jennifer A. Dumont,John V. Amari,Qi Lu,Greg Zarbis-Papastoitsis,Thomas J. Reidy,Elizabeth P. Merricks,Timothy C. Nichols,Alan J. Bitonti
View Articletitled, Prolonged activity of factor IX as a monomeric Fc fusion protein
Molecular characterization of in-frame and out-of-frame alternative splicings in coagulation factor XI pre-mRNA
Rosanna Asselta,Valeria Rimoldi,Ilaria Guella,Giulia Soldà,Raimondo De Cristofaro,Flora Peyvandi,Stefano Duga
View Articletitled, Molecular characterization of in-frame and out-of-frame alternative splicings in coagulation factor XI pre-mRNA
Supplemental data

TRANSFUSION MEDICINE

The neutrophil alloantigen HNA-3a (5b) is located on choline transporter-like protein 2 and appears to be encoded by an R>Q154 amino acid substitution
Brief Report
Brian R. Curtis,Nancy J. Cox,Mia J. Sullivan,Anuar Konkashbaev,Krista Bowens,Kirk Hansen,Richard H. Aster
View Articletitled, The neutrophil alloantigen HNA-3a (5b) is located on choline transporter-like protein 2 and appears to be encoded by an R&gt;Q154 amino acid substitution
Supplemental data

TRANSPLANTATION

Antibodies specifically target AML antigen NuSAP1 after allogeneic bone marrow transplantation
Persis P. Wadia,Marc Coram,Randall J. Armstrong,Michael Mindrinos,Atul J. Butte,David B. Miklos
View Articletitled, Antibodies specifically target AML antigen NuSAP1 after allogeneic bone marrow transplantation
Supplemental data
Human rhinovirus and coronavirus detection among allogeneic hematopoietic stem cell transplantation recipients
Filippo Milano,Angela P. Campbell,Katherine A. Guthrie,Jane Kuypers,Janet A. Englund,Lawrence Corey,Michael Boeckh
View Articletitled, Human rhinovirus and coronavirus detection among allogeneic hematopoietic stem cell transplantation recipients
Induction of tolerance to bone marrow allografts by donor-derived host nonreactive ex vivo–induced central memory CD8 T cells
Eran Ophir,Yaki Eidelstein,Ran Afik,Esther Bachar-Lustig,Yair Reisner
View Articletitled, Induction of tolerance to bone marrow allografts by donor-derived host nonreactive ex vivo–induced central memory CD8 T cells
Supplemental data

VASCULAR BIOLOGY

15(S)-hydroxyeicosatetraenoic acid–induced angiogenesis requires Src-mediated Egr-1–dependent rapid induction of FGF-2 expression
Venkatesh Kundumani-Sridharan,Jixiao Niu,Dong Wang,Dong Van Quyen,Qiuhua Zhang,Nikhlesh K. Singh,Jaganathan Subramani,Saradasri Karri,Gadiparthi N. Rao
View Articletitled, 15(S)-hydroxyeicosatetraenoic acid–induced angiogenesis requires Src-mediated Egr-1–dependent rapid induction of FGF-2 expression

CORRESPONDENCE

Challenging the adult T-cell leukemia/lymphoma (ATL) stem cell concept based on limiting dilution transplantation assay
Thierry Bonnefoix,Mary Callanan
View Articletitled, Challenging the adult T-cell leukemia/lymphoma (ATL) stem cell concept based on limiting dilution transplantation assay
Response: Estimating frequency of cancer stem cells in a mouse model of adult T-cell leukemia/lymphoma
Jumpei Yamazaki,Takuo Mizukami,William W. Hall,Isao Hamaguchi
View Articletitled, Response: Estimating frequency of cancer stem cells in a mouse model of adult T-cell leukemia/lymphoma
All Issues

Advertisement

Asciminib is a novel inhibitor of ABL1 and ABL2 gene fusions in ALL but requires the ABL SH3 domain for efficacy
NGS-based stratification refines the risk stratification in T-ALL and identifies a Very High-Risk subgroup of patients
Foxo1 is an iron-responsive transcriptional factor regulating systemic iron homeostasis
How I Treat Low-risk Polycythemia Vera Patients who Require Cytoreduction
How I manage major hemorrhage

Advertisement

Advertisement

  • American Society of Hematology
  • 2021 L Street NW, Suite 900
  • Washington, DC 20036
  • TEL +1 202-776-0544
  • FAX +1 202-776-0545

ASH Publications

American Society of Hematology

Copyright 2024 by American Society of Hematology
 
Close Modal
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal

Advertisement