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Alan J. Bitonti
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Journal Articles

Prolonged activity of a recombinant factor VIII-Fc fusion protein in hemophilia A mice and dogs

Clinical Trials & Observations
Jennifer A. Dumont, Tongyao Liu, Susan C. Low, Xin Zhang, George Kamphaus, Paul Sakorafas, Cara Fraley, Douglas Drager, Thomas Reidy, Justin McCue, Helen W. G. Franck, Elizabeth P. Merricks, Timothy C. Nichols, Alan J. Bitonti, Glenn F. Pierce, Haiyan Jiang
Journal: Blood
Blood (2012) 119 (13): 3024–3030.
https://doi.org/10.1182/blood-2011-08-367813
Published: 2012
Includes: Supplemental data
Journal Articles

Recombinant factor IX-Fc fusion protein (rFIXFc) demonstrates safety and prolonged activity in a phase 1/2a study in hemophilia B patients

Clinical Trials & Observations
Amy D. Shapiro, Margaret V. Ragni, Leonard A. Valentino, Nigel S. Key, Neil C. Josephson, Jerry S. Powell, Gregory Cheng, Arthur R. Thompson, Jaya Goyal, Karen L. Tubridy, Robert T. Peters, Jennifer A. Dumont, Donald Euwart, Lian Li, Bengt Hallén, Peter Gozzi, Alan J. Bitonti, Haiyan Jiang, Alvin Luk, Glenn F. Pierce
Journal: Blood
Blood (2012) 119 (3): 666–672.
https://doi.org/10.1182/blood-2011-07-367003
Published: 2012
Includes: Supplemental data
Journal Articles

Prolonged activity of factor IX as a monomeric Fc fusion protein

Robert T. Peters, Susan C. Low, George D. Kamphaus, Jennifer A. Dumont, John V. Amari, Qi Lu, Greg Zarbis-Papastoitsis, Thomas J. Reidy, Elizabeth P. Merricks, Timothy C. Nichols, Alan J. Bitonti
Journal: Blood
Blood (2010) 115 (10): 2057–2064.
https://doi.org/10.1182/blood-2009-08-239665
Published: 2010
Journal Articles

Factor VIII-Fc Fusion Protein Shows Extended Half-Life and Hemostatic Activity in Hemophilia A Dogs.

Jennifer A Dumont, PhD, George D Kamphaus, PhD, Cara Fraley, MS, Tamera Ashworth, BS, Helen Franck, BS, Elizabeth P. Merricks, BS, Timothy C. Nichols, MD, Alan J Bitonti, PhD
Journal: Blood
Blood (2009) 114 (22): 545.
https://doi.org/10.1182/blood.V114.22.545.545
Published: 2009