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Journal Articles

Phase 3 study of recombinant factor VIII Fc fusion protein in severe hemophilia A

Clinical Trials & Observations
Johnny Mahlangu, Jerry S. Powell, Margaret V. Ragni, Pratima Chowdary, Neil C. Josephson, Ingrid Pabinger, Hideji Hanabusa, Naresh Gupta, Roshni Kulkarni, Patrick Fogarty, David Perry, Amy Shapiro, K. John Pasi, Shashikant Apte, Ivan Nestorov, Haiyan Jiang, Shuanglian Li, Srividya Neelakantan, Lynda M. Cristiano, Jaya Goyal, Jurg M. Sommer, Jennifer A. Dumont, Nigel Dodd, Karen Nugent, Gloria Vigliani, Alvin Luk, Aoife Brennan, Glenn F. Pierce
Journal: Blood
Blood (2014) 123 (3): 317–325.
https://doi.org/10.1182/blood-2013-10-529974
Published: 2014
Includes: Supplemental data
Journal Articles

Safety and prolonged activity of recombinant factor VIII Fc fusion protein in hemophilia A patients

Clinical Trials & Observations
Jerry S. Powell, Neil C. Josephson, Doris Quon, Margaret V. Ragni, Gregory Cheng, Ella Li, Haiyan Jiang, Lian Li, Jennifer A. Dumont, Jaya Goyal, Xin Zhang, Jurg Sommer, Justin McCue, Margaret Barbetti, Alvin Luk, Glenn F. Pierce
Journal: Blood
Blood (2012) 119 (13): 3031–3037.
https://doi.org/10.1182/blood-2011-09-382846
Published: 2012
Includes: Supplemental data
Journal Articles

Recombinant factor IX-Fc fusion protein (rFIXFc) demonstrates safety and prolonged activity in a phase 1/2a study in hemophilia B patients

Clinical Trials & Observations
Amy D. Shapiro, Margaret V. Ragni, Leonard A. Valentino, Nigel S. Key, Neil C. Josephson, Jerry S. Powell, Gregory Cheng, Arthur R. Thompson, Jaya Goyal, Karen L. Tubridy, Robert T. Peters, Jennifer A. Dumont, Donald Euwart, Lian Li, Bengt Hallén, Peter Gozzi, Alan J. Bitonti, Haiyan Jiang, Alvin Luk, Glenn F. Pierce
Journal: Blood
Blood (2012) 119 (3): 666–672.
https://doi.org/10.1182/blood-2011-07-367003
Published: 2012
Includes: Supplemental data
Journal Articles

A Standardized Rotation Thromboelastometry (ROTEM) Method for Evaluation of FVIII and FIX Products in a Multi-National Clinical Trial

Frank Driessler, PhD, Xiaolei Li, PhD, Tongyao Liu, Xin Zhang, M.D., Haiyan Jiang, PhD, Alvin Luk, PhD, Glenn F Pierce, M.D., PhD, Jurg M Sommer, PhD
Journal: Blood
Blood (2011) 118 (21): 1199.
https://doi.org/10.1182/blood.V118.21.1199.1199
Published: 2011
Journal Articles

Human Immune Responses to AAV-2 Capsid May Limit Duration of Expression in Liver-Directed Gene Transfer in Humans with Hemophilia B.

Katherine High, MD, Michael Tigges, PhD, Catherine Manno, MD, Denise Sabatino, PhD, Valder Arruda, MD, Roland Herzog, PhD, Pradip Rustagi, MD, John Rasko, MD, Jurg Sommer, PhD, Kristen Jaworski, RN, Margaret Ragni, MD, Bertil Glader, MD, Ruth Lessard, Alvin Luk, PhD, Linda Couto, PhD, Haiyan Jiang, PhD, Glenn Pierce, MD, Mark Kay, MD
Journal: Blood
Blood (2004) 104 (11): 413.
https://doi.org/10.1182/blood.V104.11.413.413
Published: 2004