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Journal Articles

Safety and prolonged activity of recombinant factor VIII Fc fusion protein in hemophilia A patients

Clinical Trials & Observations
Jerry S. Powell, Neil C. Josephson, Doris Quon, Margaret V. Ragni, Gregory Cheng, Ella Li, Haiyan Jiang, Lian Li, Jennifer A. Dumont, Jaya Goyal, Xin Zhang, Jurg Sommer, Justin McCue, Margaret Barbetti, Alvin Luk, Glenn F. Pierce
Journal: Blood
Blood (2012) 119 (13): 3031–3037.
https://doi.org/10.1182/blood-2011-09-382846
Published: 2012
Includes: Supplemental data
Journal Articles

Enhanced Efficacy of Recombinant Factor VIII in Non-Covalent Complex with PEGylated Liposome in Hemophilia A Mice.

Junliang Pan, PhD, Tongyao Liu, Ji-Yun Kim, PhD, Chandra Patel, PhD, Jim Newgren, MS, Jurg Sommer, PhD, Glenn Pierce, MD, PhD, Haiyan Jiang, PhD
Journal: Blood
Blood (2007) 110 (11): 3149.
https://doi.org/10.1182/blood.V110.11.3149.3149
Published: 2007
Journal Articles

Effects of transient immunosuppression on adenoassociated, virus-mediated, liver-directed gene transfer in rhesus macaques and implications for human gene therapy

Haiyan Jiang, Linda B. Couto, Susannah Patarroyo-White, Tongyao Liu, Dea Nagy, Joseph A. Vargas, Shangzhen Zhou, Ciaran D. Scallan, Jurg Sommer, Sharmila Vijay, Federico Mingozzi, Katherine A. High, Glenn F. Pierce
Journal: Blood
Blood (2006) 108 (10): 3321–3328.
https://doi.org/10.1182/blood-2006-04-017913
Published: 2006
Journal Articles

AAV8-Factor IX Hepatic Gene Transfer with Transient Immunosuppression Is Safe but Is Abrogated by Low Titers of Neutralizing Antibody in Rhesus Macaques.

Haiyan Jiang, PhD, Susannah Patarroyo-White, BS, Tongyao Liu, BS, Bin Yang, Ph.D, Dea Nagy, M.D, Lin He, M.D, Ciaran D. Scallan, Ph.D, Jurg Sommer, Ph.D, Shangzhen Zhou, M.D, Linda B. Couto, Ph.D, Katherine A. High, M.D, Glenn F. Pierce, M.D/Ph.D
Journal: Blood
Blood (2005) 106 (11): 5532.
https://doi.org/10.1182/blood.V106.11.5532.5532
Published: 2005
Journal Articles

Human Immune Responses to AAV-2 Capsid May Limit Duration of Expression in Liver-Directed Gene Transfer in Humans with Hemophilia B.

Katherine High, MD, Michael Tigges, PhD, Catherine Manno, MD, Denise Sabatino, PhD, Valder Arruda, MD, Roland Herzog, PhD, Pradip Rustagi, MD, John Rasko, MD, Jurg Sommer, PhD, Kristen Jaworski, RN, Margaret Ragni, MD, Bertil Glader, MD, Ruth Lessard, Alvin Luk, PhD, Linda Couto, PhD, Haiyan Jiang, PhD, Glenn Pierce, MD, Mark Kay, MD
Journal: Blood
Blood (2004) 104 (11): 413.
https://doi.org/10.1182/blood.V104.11.413.413
Published: 2004