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Journal Articles

Evaluation of Longitudinal Pain Study in Sickle Cell Disease (ELIPSIS) by patient-reported outcomes, actigraphy, and biomarkers

Debra D. Pittman, Patrick C. Hines, David Beidler, Denis Rybin, Andrew L. Frelinger, III, Alan D. Michelson, Ke Liu, Xiufeng Gao, Jennell White, Ahmar U. Zaidi, Robert J. Charnigo, Michael U. Callaghan

Blood (2021) 137 (15): 2010–2020.

https://doi.org/10.1182/blood.2020006020

Published: 2021

Includes: Supplemental data

Journal Articles

A phase 3 double-blind study of the addition of tocilizumab vs placebo to cyclosporin/methotrexate GVHD prophylaxis

Blood (2021) 137 (14): 1970–1979.

https://doi.org/10.1182/blood.2020009050

Published: 2021

Includes: Supplemental data

Journal Articles

Role of c-Myc haploinsufficiency in the maintenance of HSCs in mice

Yue Sheng, Rui Ma, Chunjie Yu, Qiong Wu, Steven Zhang, Kimberly Paulsen, Jiwang Zhang, Hongyu Ni, Yong Huang, Yi Zheng, Zhijian Qian

Blood (2021) 137 (5): 610–623.

https://doi.org/10.1182/blood.2019004688

Published: 2021

Includes: Supplemental data

Journal Articles

Cytokines and costimulation in acute graft-versus-host disease

Geoffrey R. Hill, Motoko Koyama

Blood (2020) 136 (4): 418–428.

https://doi.org/10.1182/blood.2019000952

Published: 2020

Journal Articles

Altered microRNA expression links IL6 and TNF-induced inflammaging with myeloid malignancy in humans and mice

Jennifer M. Grants, Joanna Wegrzyn, Tony Hui, Kieran O’Neill, Marion Shadbolt, David J. H. F. Knapp, Jeremy Parker, Yu Deng, Aparna Gopal, T. Roderick Docking, Megan Fuller, Jenny Li, Mark Boldin, Connie J. Eaves, Martin Hirst, Aly Karsan

Blood (2020) 135 (25): 2235–2251.

https://doi.org/10.1182/blood.2019003105

Published: 2020

Includes: Supplemental data

Journal Articles

Increased mTOR activation in idiopathic multicentric Castleman disease

Daniel J. Arenas, Katherine Floess, Dale Kobrin, Ruth-Anne Langan Pai, Maya B. Srkalovic, Mark-Avery Tamakloe, Rozena Rasheed, Jasira Ziglar, Johnson Khor, Sophia A. T. Parente, Sheila K. Pierson, Daniel Martinez, Gerald B. Wertheim, Taku Kambayashi, Joseph Baur, David T. Teachey, David C. Fajgenbaum

Blood (2020) 135 (19): 1673–1684.

https://doi.org/10.1182/blood.2019002792

Published: 2020

Includes: Supplemental data

Journal Articles

Assessment of ST2 for risk of death following graft-versus-host disease in pediatric and adult age groups

Courtney M. Rowan, Francis Pike, Kenneth R. Cooke, Robert Krance, Paul A. Carpenter, Christine Duncan, David A. Jacobsohn, Catherine M. Bollard, Conrad Russell Y. Cruz, Abhijeet Malatpure, Sherif S. Farag, Jamie Renbarger, Hao Liu, Giorgos Bakoyannis, Samir Hanash, Sophie Paczesny

Blood (2020) 135 (17): 1428–1437.

https://doi.org/10.1182/blood.2019002334

Published: 2020

Includes: Supplemental data

Journal Articles

Overview of Castleman disease

Angela Dispenzieri, David C. Fajgenbaum

Blood (2020) 135 (16): 1353–1364.

https://doi.org/10.1182/blood.2019000931

Published: 2020

Journal Articles

Myeloid cell–targeted miR-146a mimic inhibits NF-κB–driven inflammation and leukemia progression in vivo

Yu-Lin Su, Xiuli Wang, Mati Mann, Tomasz P. Adamus, Dongfang Wang, Dayson F. Moreira, Zhuoran Zhang, Ching Ouyang, Xin He, Bin Zhang, Piotr M. Swiderski, Stephen J. Forman, David Baltimore, Ling Li, Guido Marcucci, Mark P. Boldin, Marcin Kortylewski

Blood (2020) 135 (3): 167–180.

https://doi.org/10.1182/blood.2019002045

Published: 2020

Includes: Supplemental data

Journal Articles

Targeting chronic NFAT activation with calcineurin inhibitors in diffuse large B-cell lymphoma

Philip Bucher, Tabea Erdmann, Paula Grondona, Wendan Xu, Anja Schmitt, Christoph Schürch, Myroslav Zapukhlyak, Caroline Schönfeld, Edgar Serfling, Daniela Kramer, Michael Grau, Pavel Klener, Claudia Lengerke, Klaus Schulze-Osthoff, Georg Lenz, Stephan Hailfinger

Blood (2020) 135 (2): 121–132.

https://doi.org/10.1182/blood.2019001866

Published: 2020

Includes: Supplemental data

Journal Articles

IL-6 dysregulation originates in dendritic cells and mediates graft-versus-host disease via classical signaling

Andrew N. Wilkinson, Karshing Chang, Rachel D. Kuns, Andrea S. Henden, Simone A. Minnie, Kathleen S. Ensbey, Andrew D. Clouston, Ping Zhang, Motoko Koyama, Juan Hidalgo, Stefan Rose-John, Antiopi Varelias, Slavica Vuckovic, Kate H. Gartlan, Geoffrey R. Hill

Blood (2019) 134 (23): 2092–2106.

https://doi.org/10.1182/blood.2019000396

Published: 2019

Includes: Supplemental data

Journal Articles

The Ribosomal Biogenesis Inhibitor CX-5461 Is an Anti-Cancer Therapeutic That Increases Platelet Count in Mice and in Humans

Amandeep Kaur, PhD, Katherine M Hannan, PhD, Samina Nazir, MSc, Kylee H Maclachlan, FRACP,FRCPA, Gretchen Poortinga, PhD, Si Ming Man, PhD, Simon Harrison, MBBS, MRCP, FRCPath, FRACP, PhD, Ross D Hannan, PhD, Elizabeth E. Gardiner, PhD

Blood (2019) 134 (Supplement_1): 2360.

https://doi.org/10.1182/blood-2019-121713

Published: 2019

Journal Articles

An Adaptive Design Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Emapalumab in Adult Patients with Non-Primary Hemophagocytic Lymphohistiocytosis

Veronica Asnaghi, MD, Maria Ballabio, MD, Philippe Jacqmin, Kathy de Graaf, Cristina De Min, MD

Blood (2019) 134 (Supplement_1): 2333.

https://doi.org/10.1182/blood-2019-123995

Published: 2019

Journal Articles

A Rise in Plasma Coagulability during the First 3 Months Following Provoked Venous Thromboembolism Is Associated with the Development of Post-Thrombotic Syndrome in Children and Young Adults: Analysis of the Kids-DOTT Multicenter Trial-Derived Biobank

Marisol Betensky, MDMPH, Ernest Amankwah, PhD, Stephanie Brandal, Allen Everett, MD, Neil A Goldenberg, MD PhD

Blood (2019) 134 (Supplement_1): 2424.

https://doi.org/10.1182/blood-2019-131821

Published: 2019

Journal Articles

A Feasibility and Safety Study of a New CD19-Directed Fast CAR-T Therapy for Refractory and Relapsed B Cell Acute Lymphoblastic Leukemia

Blood (2019) 134 (Supplement_1): 825.

https://doi.org/10.1182/blood-2019-121751

Published: 2019

Journal Articles

Elucidating the Role of IL6 in Stress Erythropoiesis and in the Development of Anemia Under Inflammatory Conditions

Sayantani Sinha, PhD, Ritama Gupta, PhD, Jianbing Zhang, PhD, Amaliris Guerra, PhD, Ping La, Sara Gardenghi, PhD, Stefano Rivella, PhD

Blood (2019) 134 (Supplement_1): 940.

https://doi.org/10.1182/blood-2019-128826

Published: 2019

Journal Articles

First-in-Human, Phase 1/2 Trial to Assess the Safety and Clinical Activity of Subcutaneous GEN3013 (DuoBody ® -CD3×CD20) in B-Cell Non-Hodgkin Lymphomas

Pieternella Lugtenburg, MD PhD, Rogier Mous, MD PhD, Michael Roost Clausen, Martine E.D. Chamuleau, Peter Johnson, MDFRCP, Kim Linton, PhD, Simon Rule, Roberto S Oliveri, MD PhD, Dena DeMarco, Ida H Hiemstra, PhD, Guang Chen, Ada Azaryan, Manish Gupta, Tahamtan Ahmadi, Martin Hutchings, MD PhD

Blood (2019) 134 (Supplement_1): 758.

https://doi.org/10.1182/blood-2019-121460

Published: 2019

Journal Articles

Sickle Cell Hemoglobin Impairs Lysosomal Processing in Macrophages Leading to Inflammasome Activation and Inflammation

Marina Jerebtsova, PhD, Xiaomei Niu, MD, Sharmin Diaz, NP, Namita Kumari, PhD, Sergei Nekhai, PhD

Blood (2019) 134 (Supplement_1): 979.

https://doi.org/10.1182/blood-2019-130741

Published: 2019

Journal Articles

Phase 1 First-in-Human Trial of AMV564, a Bivalent Bispecific (2:2) CD33/CD3 T-Cell Engager, in Patients with Relapsed/Refractory Acute Myeloid Leukemia (AML)

Peter Westervelt, MD PhD, Jorge E. Cortes, MD, Jessica K. Altman, Meixiao Long, MD, Vivian G. Oehler, MD, Ivana Gojo, MD, Jeanmarie Guenot, PhD, Patrick Chun, MD, Gail J. Roboz, MD

Blood (2019) 134 (Supplement_1): 834.

https://doi.org/10.1182/blood-2019-129042

Published: 2019

Journal Articles

Genetically Engineered Hematopoietic Progenitors Derived from Human Induced Pluripotent Stem Cells Achieve the Feeder-Free and Robust Production of Neutrophils with the Functional Capacity In Vivo

Masashi Miyauchi, Yusuke ITO, MD, Fumio Nakahara, MD PhD, Fumi Nakamura, MD PhD, Yuki Iwasaki, Taiki Kawagoshi, Yuki Kagoya, MD PhD, Shunya Arai, MD PhD, Mineo Kurokawa, MD PhD

Blood (2019) 134 (Supplement_1): 720.

https://doi.org/10.1182/blood-2019-126348

Published: 2019

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Evaluation of Longitudinal Pain Study in Sickle Cell Disease (ELIPSIS) by patient-reported outcomes, actigraphy, and biomarkers

A phase 3 double-blind study of the addition of tocilizumab vs placebo to cyclosporin/methotrexate GVHD prophylaxis

Role of c-Myc haploinsufficiency in the maintenance of HSCs in mice

Cytokines and costimulation in acute graft-versus-host disease

Altered microRNA expression links IL6 and TNF-induced inflammaging with myeloid malignancy in humans and mice

Increased mTOR activation in idiopathic multicentric Castleman disease

Assessment of ST2 for risk of death following graft-versus-host disease in pediatric and adult age groups

Overview of Castleman disease

Myeloid cell–targeted miR-146a mimic inhibits NF-κB–driven inflammation and leukemia progression in vivo

Targeting chronic NFAT activation with calcineurin inhibitors in diffuse large B-cell lymphoma

IL-6 dysregulation originates in dendritic cells and mediates graft-versus-host disease via classical signaling

The Ribosomal Biogenesis Inhibitor CX-5461 Is an Anti-Cancer Therapeutic That Increases Platelet Count in Mice and in Humans

An Adaptive Design Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Emapalumab in Adult Patients with Non-Primary Hemophagocytic Lymphohistiocytosis

A Rise in Plasma Coagulability during the First 3 Months Following Provoked Venous Thromboembolism Is Associated with the Development of Post-Thrombotic Syndrome in Children and Young Adults: Analysis of the Kids-DOTT Multicenter Trial-Derived Biobank

A Feasibility and Safety Study of a New CD19-Directed Fast CAR-T Therapy for Refractory and Relapsed B Cell Acute Lymphoblastic Leukemia

Elucidating the Role of IL6 in Stress Erythropoiesis and in the Development of Anemia Under Inflammatory Conditions

First-in-Human, Phase 1/2 Trial to Assess the Safety and Clinical Activity of Subcutaneous GEN3013 (DuoBody ® -CD3×CD20) in B-Cell Non-Hodgkin Lymphomas

Sickle Cell Hemoglobin Impairs Lysosomal Processing in Macrophages Leading to Inflammasome Activation and Inflammation

Phase 1 First-in-Human Trial of AMV564, a Bivalent Bispecific (2:2) CD33/CD3 T-Cell Engager, in Patients with Relapsed/Refractory Acute Myeloid Leukemia (AML)

Genetically Engineered Hematopoietic Progenitors Derived from Human Induced Pluripotent Stem Cells Achieve the Feeder-Free and Robust Production of Neutrophils with the Functional Capacity In Vivo

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