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Journal Articles

Assessing Real-Time Sickling Kinetics in Individual Cells from Erythrocyte Populations of Subjects with Different HbA, HbS and HbF Percentages

Aliya U. Zaidi, Xiufeng Gao, Robert Goodrich, Marta Ferranti, Rasa Borhan, Ke Liu, Nnamdi Okeke, Michael Tarasev, Mariama Kabore, Courtney D. Fitzhugh, Priya Sethu Chockalingam, Patrick C. Hines

Blood (2023) 142 (Supplement 1): 1118.

https://doi.org/10.1182/blood-2023-190404

Published: 2023

Journal Articles

Red Blood Cell Deformability and Morphological Dynamic Sickling As a Metric to Monitor Pharmacodynamic Response to Voxelotor

Marta Ferranti, Jordan Antongiorgi, Robert Goodrich, Xiufeng Gao, Ke Liu, Nnamdi Okeke, Michael Tarasev, Patrick C. Hines

Blood (2023) 142 (Supplement 1): 5260.

https://doi.org/10.1182/blood-2023-190246

Published: 2023

Journal Articles

Evaluation of Longitudinal Pain Study in Sickle Cell Disease (ELIPSIS) by patient-reported outcomes, actigraphy, and biomarkers

Debra D. Pittman, Patrick C. Hines, David Beidler, Denis Rybin, Andrew L. Frelinger, III, Alan D. Michelson, Ke Liu, Xiufeng Gao, Jennell White, Ahmar U. Zaidi, Robert J. Charnigo, Michael U. Callaghan

Blood (2021) 137 (15): 2010–2020.

https://doi.org/10.1182/blood.2020006020

Published: 2021

Includes: Supplemental data

Journal Articles

Hemolytic Biomarkers Predict Adhesiveness of Sickle Blood Cells in a Clinical Adhesion Bioassay

Jennell White, PhD, Xiufeng Gao, MD, Michael Tarasev, Michael.tarasev@functionalfluidics.com, Ke Liu, PhD, Michael U. Callaghan, MD, Patrick C. Hines, MDPhD

Blood (2020) 136 (Supplement 1): 31.

https://doi.org/10.1182/blood-2020-143402

Published: 2020

Journal Articles

PP-14, a Novel Structurally-Enhanced Antisickling Allosteric Hemoglobin Effector, Increases Oxygen Affinity and Disrupts Hemoglobin S Polymer Formation

Martin K. Safo, PhD, Piyusha P Pagare, PhD, Mohini Ghatge, PhD, Carla Casu, PhD, Valentina Ghiaccio, PhD, Nancy Anabaraonye, Xiaomeng Xu, MS, Stefano Rivella, PhD, Patrick C. Hines, MD PhD, Ke Liu, PhD, Yan Zhang, PhD, Jürgen Venitz, MD PhD, Osheiza Abdulmalik, DVM

Blood (2019) 134 (Supplement_1): 73.

https://doi.org/10.1182/blood-2019-128646

Published: 2019

Journal Articles

A Standardized Clinical Flow Adhesion Assay of Whole Blood Adhesion to VCAM-1 Predicts Severe SCD Phenotypes in a 2-Yr Prospective Observational Follow-up of the Original Elipsis Cohort

Patrick C. Hines, MD PhD, Ahmar Urooj Zaidi, MD, Xiufeng Gao, MD, Ke Liu, PhD, Muhammad O. Shareef, Michael Callaghan, Jennell White, PhD

Blood (2019) 134 (Supplement_1): 3562.

https://doi.org/10.1182/blood-2019-126371

Published: 2019

Journal Articles

Regulatory T Cell Selective IL-2-Fc Fusion Proteins for the Treatment of Autoimmune Diseases

Rajat Varma, PhD, Ke Liu, PhD, Kendra Avery, PhD, Rumana Rashid, PhD, Suzanne Schubbert, PhD, Irene Leung, PhD, Christine Bonzon, PhD, Liz Bogaert, PhD, John Desjarlais, Matthew J. Bernett

Blood (2018) 132 (Supplement 1): 3709.

https://doi.org/10.1182/blood-2018-99-117622

Published: 2018

Journal Articles

Longitudinal Evaluation of a Standardized P-Selectin Flow Adhesion Bioassay: Potential Role for the Assessment and Prediction of Vaso-Occlusive Episodes in Sickle Cell Disease

Ke Liu, PhD, Xiufeng Gao, MD, Jennell White, PhD, Michael U. Callaghan, MD, Patrick C. Hines, MD PhD

Blood (2018) 132 (Supplement 1): 1096.

https://doi.org/10.1182/blood-2018-99-120084

Published: 2018

Journal Articles

A Longitudinal Study to Identify and Assess Adhesion Indices during Vaso-Occlusive Crises in Adults and Adolescents with Sickle Cell Disease

Jennell White, PhD, Xiufeng Gao, MD, Ke Liu, PhD, Michael U. Callaghan, MD, Patrick C. Hines, MD PhD

Blood (2018) 132 (Supplement 1): 1097.

https://doi.org/10.1182/blood-2018-99-120311

Published: 2018

Journal Articles

Elipsis: A Longitudinal Study of Electronic Patient-Reported Outcomes, Actigraphy and Biomarkers to Identify and Assess at-Home Vaso-Occlusive Crises in Adults and Adolescents with Sickle Cell Disease

Michael U. Callaghan, Patrick C. Hines, MD PhD, Debra D Pittman, MS, David Beidler, PhD, Denis Rybin, PhD, Ahmar Urooj Zaidi, MD BSc, Jennell White, PhD, Ke Liu, PhD, Bryan Hannan, MS, Xiufeng Gao, MD, Andreas M Pleil, PhD, Alexandra Barsdorf, PhD, Martin David, Pharm D, Melanie Simmons, PMP, PSM, Andrew L Frelinger, III, PhD, Alan D Michelson, MD, Nick Clarke, PhD, Robert J Charnigo, MS

Blood (2017) 130 (Supplement 1): 973.

https://doi.org/10.1182/blood.V130.Suppl_1.973.973

Published: 2017

Journal Articles

Sevuparin Blocks Sickle Blood Cell Adhesion and Sickle-Leukocyte Rolling on Immobilized L-Selectin in a Dose Dependent Manner

Maria Lindgren, PhD, Jennell White, PhD, Ke Liu, PhD, Lena Jendeberg, PhD, Patrick C. Hines, MD PhD

Blood (2016) 128 (22): 2482.

https://doi.org/10.1182/blood.V128.22.2482.2482

Published: 2016

Journal Articles

Evaluation of Purified Poloxamer-188 (vepoloxamer) on Sickle Red Blood Cell (RBC) Membrane Function Properties

Jennell White, PhD, Patrick C. Hines, MD PhD, Ke Liu, PhD, Lennette J. Benjamin, MD, Xiufeng Gao, Martin Emanuele, PhD

Blood (2015) 126 (23): 2180.

https://doi.org/10.1182/blood.V126.23.2180.2180

Published: 2015

Journal Articles

Role of a 5′-enhancer in the transcriptional regulation of the human endothelial cell protein C receptor gene

Luigina R. Mollica, James T. B. Crawley, Ke Liu, James B. Rance, Peter N. Cockerill, George A. Follows, Josette-Renee Landry, Dominic J. Wells, David A. Lane

Blood (2006) 108 (4): 1251–1259.

https://doi.org/10.1182/blood-2006-02-001461

Published: 2006

Includes: Supplemental data

NARROW

Assessing Real-Time Sickling Kinetics in Individual Cells from Erythrocyte Populations of Subjects with Different HbA, HbS and HbF Percentages

Red Blood Cell Deformability and Morphological Dynamic Sickling As a Metric to Monitor Pharmacodynamic Response to Voxelotor

Evaluation of Longitudinal Pain Study in Sickle Cell Disease (ELIPSIS) by patient-reported outcomes, actigraphy, and biomarkers

Hemolytic Biomarkers Predict Adhesiveness of Sickle Blood Cells in a Clinical Adhesion Bioassay

PP-14, a Novel Structurally-Enhanced Antisickling Allosteric Hemoglobin Effector, Increases Oxygen Affinity and Disrupts Hemoglobin S Polymer Formation

A Standardized Clinical Flow Adhesion Assay of Whole Blood Adhesion to VCAM-1 Predicts Severe SCD Phenotypes in a 2-Yr Prospective Observational Follow-up of the Original Elipsis Cohort

Regulatory T Cell Selective IL-2-Fc Fusion Proteins for the Treatment of Autoimmune Diseases

Longitudinal Evaluation of a Standardized P-Selectin Flow Adhesion Bioassay: Potential Role for the Assessment and Prediction of Vaso-Occlusive Episodes in Sickle Cell Disease

A Longitudinal Study to Identify and Assess Adhesion Indices during Vaso-Occlusive Crises in Adults and Adolescents with Sickle Cell Disease

Elipsis: A Longitudinal Study of Electronic Patient-Reported Outcomes, Actigraphy and Biomarkers to Identify and Assess at-Home Vaso-Occlusive Crises in Adults and Adolescents with Sickle Cell Disease

Sevuparin Blocks Sickle Blood Cell Adhesion and Sickle-Leukocyte Rolling on Immobilized L-Selectin in a Dose Dependent Manner

Evaluation of Purified Poloxamer-188 (vepoloxamer) on Sickle Red Blood Cell (RBC) Membrane Function Properties

Role of a 5′-enhancer in the transcriptional regulation of the human endothelial cell protein C receptor gene

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American Society of Hematology

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American Society of Hematology

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