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Journal Articles

Results from a Phase 1 Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Tebapivat (AG-946) in Patients with Sickle Cell Disease

Julia Z Xu, Enrico M Novelli, Jean-Antoine Ribeil, Andreas Glenthøj, Srila Gopal, Hanny Al-Samkari, Modupe Idowu, Jenny Despotovic, Spurthi Patil, Xiaoshu Dai, Abdullah Al Masud, Michael Callaghan, Fuad El Rassi

Blood (2024) 144 (Supplement 1): 2496.

https://doi.org/10.1182/blood-2024-203509

Published: 2024

Journal Articles

The Evaluation of Transfusion Data from the Phase 3 Clinical Study of L-Glutamine in Sickle Cell Disease

Hung Lam, Joseph M Becerra, Charles W Stark, Yutaka Niihara, Michael Callaghan

Blood (2021) 138 (Supplement 1): 3116.

https://doi.org/10.1182/blood-2021-154477

Published: 2021

Journal Articles

Trial in Progress: The Randomized, Double-Blind, Placebo-Controlled Phase IIa CROSSWALK-c Trial Evaluating the Efficacy of Crovalimab As Adjunct Treatment in the Prevention of Vaso-Occlusive Episodes (VOEs) in Patients with Sickle Cell Disease (SCD)

Michael Callaghan, Kenneth I. Ataga, Lucia De Franceschi, Caterina Minniti, Nadiesh Balachandran, Diane-Charlotte Imbs, Thomas Perretti, Julia Ramos, Alexandre Sostelly, Pablo Bartolucci

Blood (2021) 138 (Supplement 1): 3111.

https://doi.org/10.1182/blood-2021-151222

Published: 2021

Journal Articles

A Standardized Clinical Flow Adhesion Assay of Whole Blood Adhesion to VCAM-1 Predicts Severe SCD Phenotypes in a 2-Yr Prospective Observational Follow-up of the Original Elipsis Cohort

Patrick C. Hines, MD PhD, Ahmar Urooj Zaidi, MD, Xiufeng Gao, MD, Ke Liu, PhD, Muhammad O. Shareef, Michael Callaghan, Jennell White, PhD

Blood (2019) 134 (Supplement_1): 3562.

https://doi.org/10.1182/blood-2019-126371

Published: 2019

Journal Articles

Germline Mutations in ETV6 are Associated with In Vivo cytoplasmic Localization of ETV6 and Cause Transcriptional Dysregulation of Interferon Response Genes

Marlie H Fisher, Greg Kirkpatrick, PhD, Courtney L Jones, PhD, Brett M. Stevens, PhD, Michael Callaghan, MD, Eric Pietras, PhD, Kenneth L. Jones, PhD, Christopher C. Porter, MD, Jorge Di Paola, MD

Blood (2019) 134 (Supplement_1): 2316.

https://doi.org/10.1182/blood-2019-132032

Published: 2019

Journal Articles

Spontaneous Bleeding and Poor Bleeding Response with Extended Half-Life Factor IX Products: A Survey of Select US and Canadian Hemophilia Treatment Centers

Lynn M Malec, MD, Stacy E. Croteau, Michael Callaghan, MD, Davide Matino, MD MSc, Kenneth Dale Friedman, MD, Robert F. Sidonio, Jr., MD MSc

Blood (2019) 134 (Supplement_1): 2407.

https://doi.org/10.1182/blood-2019-126196

Published: 2019

Journal Articles

Studying the Role of ETV6 in Megakaryopoiesis and Thrombopoiesis Using a Novel CRISPR-Cas9 Halotag Genome Editing Strategy

Marlie H Fisher, Leila J. Noetzli, PhD, Michael Callaghan, MD, Walter H. Kahr, MDPhDFRCPC, Jesse W Rowley, PhD, Jorge Di Paola, MD

Blood (2019) 134 (Supplement_1): 2468.

https://doi.org/10.1182/blood-2019-131967

Published: 2019

Journal Articles

Factor VIII Use in the Treatment of Breakthrough Bleeds in Hemophilia A Patients without Inhibitors on Emicizumab Prophylaxis: The Phase 3 HAVEN 3 Study Experience

Michael Callaghan, MD, Benjamin Trzaskoma, MS, Richard H. Ko, MD, Lucy Lee, PharmD, Anisha M. Patel, PhD, Eunice Tzeng, PharmD, Michelle Lynn Shah, PharmD, Tiffany Y. Chang, MD MAS, Markus Niggli, PhD, Christophe Dhalluin, PhD, Johnny Mahlangu, MMed, FCPath

Blood (2019) 134 (Supplement_1): 2395.

https://doi.org/10.1182/blood-2019-123654

Published: 2019

Journal Articles

The Novel Sulfonamidebenzamide ML291 Activates Apoptotic UPR Signaling in Pediatric Leukemia

Danielle Garshott, Nicole Melong, MSc, Tania T. Sarker, MD MPH, Yue Xi, PhD, Amy Brownell, Michael Callaghan, MD, Jason N. Berman, MD, Andrew Fribley, PhD

Blood (2016) 128 (22): 3523.

https://doi.org/10.1182/blood.V128.22.3523.3523

Published: 2016

Journal Articles

Natural History Of Inhibitor Recurrence Following Successful Immune Tolerance Induction

Ana G. Antun, MD, Paul Monahan, MD, Marilyn J. Manco-Johnson, MD, Michael Callaghan, MD, Guy Young, MD, Christine Knoll, MD, Shannon Carpenter, MD, MS, Joanna A. Davis, MD, Michael F. Guerrera, MD, Rebecca Kruse-Jarres, MD, MPH, Margaret V. Ragni, MD, MPH, Char Witmer, MD, MSCE, Courtney E. McCracken, PhD, Maralee Kanin, Christine L. Kempton, MD, MSc

Blood (2013) 122 (21): 1106.

https://doi.org/10.1182/blood.V122.21.1106.1106

Published: 2013

Journal Articles

Thromboelastography for Monitoring of Hemostatic Changes Following Factor Administration

Meera B. Chitlur, MD, Latha B. Rao, MD, Michael Callaghan, MD, Madhvi Rajpurkar, MD, Jeanne M. Lusher, MD

Blood (2012) 120 (21): 3373.

https://doi.org/10.1182/blood.V120.21.3373.3373

Published: 2012

Journal Articles

Emergency Room Visits in Children with Hemophilia

Ayesha N Zia, MD, Bulent Ozgonenel, MD, Meera B. Chitlur, MD, Madhvi Rajpurkar, MD, Michael Callaghan, MD, Jeanne M. Lusher, MD

Blood (2011) 118 (21): 1227.

https://doi.org/10.1182/blood.V118.21.1227.1227

Published: 2011

Journal Articles

The Natural Product Borrelidin Induces UPR and Apoptosis in AML Cell Lines

Leah Jackson, Shelby Bechler, Justin Miller, B.S., Amy Brownell, B.S., Danielle Garshott, B.S., Michael Callaghan, MD, Andrew M Fribley, Ph.D.

Blood (2011) 118 (21): 4260.

https://doi.org/10.1182/blood.V118.21.4260.4260

Published: 2011

Journal Articles

The Utility of Thromboelastography As a Screening Test for Bleeding Disorders

Ayesha N Zia, MD, Muhammad Fawad Bilal, MD, Madhvi Rajpurkar, MD, Meera B. Chitlur, MD, Michael Callaghan, MD, Jeanne M. Lusher, MD

Blood (2011) 118 (21): 4352.

https://doi.org/10.1182/blood.V118.21.4352.4352

Published: 2011

Journal Articles

Mycophenolate Mofetil Therapy Is a Steroid Sparing In Childhood and Young Adult Chronic ITP and Evans Syndrome.

Zaher Naji, Madhvi Rajpurkar, MD, Sureyya Savasan, MD, Roland Chu, MD, Meera Chitlur, Michael Callaghan, MD

Blood (2010) 116 (21): 1441.

https://doi.org/10.1182/blood.V116.21.1441.1441

Published: 2010

NARROW

Results from a Phase 1 Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Tebapivat (AG-946) in Patients with Sickle Cell Disease

The Evaluation of Transfusion Data from the Phase 3 Clinical Study of L-Glutamine in Sickle Cell Disease

Trial in Progress: The Randomized, Double-Blind, Placebo-Controlled Phase IIa CROSSWALK-c Trial Evaluating the Efficacy of Crovalimab As Adjunct Treatment in the Prevention of Vaso-Occlusive Episodes (VOEs) in Patients with Sickle Cell Disease (SCD)

A Standardized Clinical Flow Adhesion Assay of Whole Blood Adhesion to VCAM-1 Predicts Severe SCD Phenotypes in a 2-Yr Prospective Observational Follow-up of the Original Elipsis Cohort

Germline Mutations in ETV6 are Associated with In Vivo cytoplasmic Localization of ETV6 and Cause Transcriptional Dysregulation of Interferon Response Genes

Spontaneous Bleeding and Poor Bleeding Response with Extended Half-Life Factor IX Products: A Survey of Select US and Canadian Hemophilia Treatment Centers

Studying the Role of ETV6 in Megakaryopoiesis and Thrombopoiesis Using a Novel CRISPR-Cas9 Halotag Genome Editing Strategy

Factor VIII Use in the Treatment of Breakthrough Bleeds in Hemophilia A Patients without Inhibitors on Emicizumab Prophylaxis: The Phase 3 HAVEN 3 Study Experience

The Novel Sulfonamidebenzamide ML291 Activates Apoptotic UPR Signaling in Pediatric Leukemia

Natural History Of Inhibitor Recurrence Following Successful Immune Tolerance Induction

Thromboelastography for Monitoring of Hemostatic Changes Following Factor Administration

Emergency Room Visits in Children with Hemophilia

The Natural Product Borrelidin Induces UPR and Apoptosis in AML Cell Lines

The Utility of Thromboelastography As a Screening Test for Bleeding Disorders

Mycophenolate Mofetil Therapy Is a Steroid Sparing In Childhood and Young Adult Chronic ITP and Evans Syndrome.

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American Society of Hematology

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American Society of Hematology

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