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Mikołaj Słabicki
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Journal Articles

DNMT3A Stability Is Maintained By Ubiquitin-Specific Peptidase 11 (USP11) and Sumoylation Countering Degradation

Taishi Yonezawa, Mikolaj Slabicki, Justine Rutter, Venkatasubramaniam Sundaramurthy, Gandhar Datar, Benjamin Levine Ebert, Margaret Goodell
Journal: Blood
Blood (2024) 144 (Supplement 1): 1344.
https://doi.org/10.1182/blood-2024-205801
Published: 2024
Journal Articles

PPM1D modulates hematopoietic cell fitness and response to DNA damage and is a therapeutic target in myeloid malignancy

Peter G. Miller, Adam S. Sperling, Christina Mayerhofer, Marie E. McConkey, Jana M. Ellegast, Carmen Da Silva, Drew N. Cohen, Chuqi Wang, Azeem Sharda, Ni Yan, Subha Saha, Cameron Schluter, Ilexa Schechter, Mikołaj Słabicki, Brittany Sandoval, Josephine Kahn, Steffen Boettcher, Christopher J. Gibson, David T. Scadden, Kimberly Stegmaier, Shruti Bhatt, R. Coleman Lindsley, Benjamin L. Ebert
Journal: Blood
Blood (2023) 142 (24): 2079–2091.
https://doi.org/10.1182/blood.2023020331
Published: 2023
Includes: Supplemental data
Journal Articles

UBR5 Is a Hect E3 Ubiquitin Ligase That Regulates Chromatin Bound Nuclear Hormone Receptor Stability

Jonathan M Tsai, Jacob D Aguirre, Jared Brown, Vivian Focht, Yen-Der Li, Georg Kempf, Lukas Kater, Pius Galli, Simone Cavadini, Brittany E Sandoval, Charles Zou, Justine Rutter, Katherine Donovan, Quinlan Sievers, Paul Park, Jevon A. Cutler, Charlie Hatton, Elizabeth Ener, Micah T Sperling, Mikolaj Slabicki, Peter G. Miller, Roger Belizaire, Adam S. Sperling, Scott A. Armstrong, Eric S. Fischer, Nicolas Thomä, Benjamin L. Ebert
Journal: Blood
Blood (2022) 140 (Supplement 1): 2968–2969.
https://doi.org/10.1182/blood-2022-167615
Published: 2022
Journal Articles

SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma

Anne C. Wilke, Carmen Doebele, Alena Zindel, Kwang Seok Lee, Sara A. Rieke, Michele Ceribelli, Federico Comoglio, James D. Phelan, James Q. Wang, Yana Pikman, Dominique Jahn, Björn Häupl, Constanze Schneider, Sebastian Scheich, Frances A. Tosto, Hanibal Bohnenberger, Philipp Stauder, Frank Schnütgen, Mikolaj Slabicki, Zana A. Coulibaly, Sebastian Wolf, Kamil Bojarczuk, Björn Chapuy, Christian H. Brandts, Philipp Stroebel, Caroline A. Lewis, Michael Engelke, Xincheng Xu, Hahn Kim, Thanh Hung Dang, Roland Schmitz, Daniel J. Hodson, Kimberly Stegmaier, Henning Urlaub, Hubert Serve, Clemens A. Schmitt, Fernando Kreuz, Gero Knittel, Joshua D. Rabinowitz, Hans Christian Reinhardt, Matthew G. Vander Heiden, Craig Thomas, Louis M. Staudt, Thorsten Zenz, Thomas Oellerich
Journal: Blood
Blood (2022) 139 (4): 538–553.
https://doi.org/10.1182/blood.2021012081
Published: 2022
Includes: Supplemental data
Journal Articles

Exploiting the Zinc Finger Degrome Targeted By Lenalidomide to Engineer Reversible Off-Switch Degradable Chimeric Antigen Receptors

Max Jan, MD PhD, Ana Castano, MD, Amanda Walker, BA, Andrew A Guirguis, MD PhD, Jessica A Gasser, PhD, Amanda A Bouffard, Mikolaj Slabicki, PhD, Alexander Tepper, Daniel E Grinshpun, Taeyoon Kyung, PhD, Quinlan Sievers, MD PhD, Michael E Birnbaum, PhD, Marcela V Maus, MD PhD, Benjamin L. Ebert, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 866.
https://doi.org/10.1182/blood-2019-124210
Published: 2019
Journal Articles

Patterns of substrate affinity, competition, and degradation kinetics underlie biological activity of thalidomide analogs

Adam S. Sperling, Michael Burgess, Hasmik Keshishian, Jessica A. Gasser, Shruti Bhatt, Max Jan, Mikołaj Słabicki, Rob S. Sellar, Emma C. Fink, Peter G. Miller, Brian J. Liddicoat, Quinlan L. Sievers, Rohan Sharma, Dylan N. Adams, Elyse A. Olesinski, Mariateresa Fulciniti, Namrata D. Udeshi, Eric Kuhn, Anthony Letai, Nikhil C. Munshi, Steven A. Carr, Benjamin L. Ebert
Journal: Blood
Blood (2019) 134 (2): 160–170.
https://doi.org/10.1182/blood.2019000789
Published: 2019
Includes: Supplemental data
Journal Articles

TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma

Alexander Jethwa, Mikołaj Słabicki, Jennifer Hüllein, Marius Jentzsch, Vineet Dalal, Sophie Rabe, Lena Wagner, Tatjana Walther, Wolfram Klapper, MMML Network Project, Hanibal Bohnenberger, Mandy Rettel, Junyan Lu, Arne H. Smits, Frank Stein, Mikhail M. Savitski, Wolfgang Huber, Yael Aylon, Moshe Oren, Thorsten Zenz
Journal: Blood
Blood (2018) 131 (25): 2789–2802.
https://doi.org/10.1182/blood-2017-09-806679
Published: 2018
Includes: Supplemental data
Journal Articles

HDAC6 inhibition upregulates CD20 levels and increases the efficacy of anti-CD20 monoclonal antibodies

Malgorzata Bobrowicz, Michal Dwojak, Beata Pyrzynska, Joanna Stachura, Angelika Muchowicz, Elise Berthel, Nicole Dalla-Venezia, Mieszko Kozikowski, Marta Siernicka, Nina Miazek, Piotr Zapala, Antoni Domagala, Kamil Bojarczuk, Agata Malenda, Joanna Barankiewicz, Agnieszka Graczyk-Jarzynka, Agnieszka Zagozdzon, Magdalena Gabrysiak, Jean-Jacques Diaz, Marta Karp, Ewa Lech-Maranda, Malgorzata Firczuk, Krzysztof Giannopoulos, Dimitar G. Efremov, Luca Laurenti, Dunja Baatout, Lukas Frenzel, Agata Malinowska, Mikolaj Slabicki, Thorsten Zenz, Abdessamad Zerrouqi, Jakub Golab, Magdalena Winiarska
Journal: Blood
Blood (2017) 130 (14): 1628–1638.
https://doi.org/10.1182/blood-2016-08-736066
Published: 2017
Includes: Supplemental data
Journal Articles

Recurrent CDKN1B (p27) mutations in hairy cell leukemia

Brief Report
Sascha Dietrich, Jennifer Hüllein, Stanley Chun-Wei Lee, Barbara Hutter, David Gonzalez, Sandrine Jayne, Martin J. S. Dyer, Małgorzata Oleś, Monica Else, Xiyang Liu, Mikołaj Słabicki, Bian Wu, Xavier Troussard, Jan Dürig, Mindaugas Andrulis, Claire Dearden, Christof von Kalle, Martin Granzow, Anna Jauch, Stefan Fröhling, Wolfgang Huber, Manja Meggendorfer, Torsten Haferlach, Anthony D. Ho, Daniela Richter, Benedikt Brors, Hanno Glimm, Estella Matutes, Omar Abdel Wahab, Thorsten Zenz
Journal: Blood
Blood (2015) 126 (8): 1005–1008.
https://doi.org/10.1182/blood-2015-04-643361
Published: 2015
Includes: Supplemental data
Journal Articles

Understanding CD20 Regulation By Loss-Of-Function RNAi Screen

Mikolaj Slabicki, PhD, Leopold Sellner, MD, Alexander Jethwa, Tatjana Stolz, Srinivas Mamidi, PhD, Michael Boettcher, PhD, Michael Kirschfink, Thorsten Zenz, MD
Journal: Blood
Blood (2013) 122 (21): 4221.
https://doi.org/10.1182/blood.V122.21.4221.4221
Published: 2013
Journal Articles

Systematic Mapping Of Drug and Pathway Sensitivity In Chronic Lymphocytic Leukemia Identifies Synthetic Lethal Interactions Of Mutant p53

Leopold Sellner, MD, Oles Malgorzata, Mikolaj Slabicki, PhD, Carolin Blume, Hüllein Jennifer, Tatjana Stolz, Martin Sill, PhD, Sascha Dietrich, MD, Olaf Merkel, PhD, Anna Jauch, PhD, Manfred Hensel, MD, Davide Rossi, Zirlik Katja, MD, Martina Seiffert, PhD, Anthony D. Ho, MD, von Kalle Christof, MD, Hanno Glimm, MD, Wolfgang Huber, PhD, Thorsten Zenz, MD
Journal: Blood
Blood (2013) 122 (21): 173.
https://doi.org/10.1182/blood.V122.21.173.173
Published: 2013