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Amanda A Bouffard
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Journal Articles

CD70 CAR T cells secreting an anti-CD33/anti-CD3 dual targeting antibody overcome antigen heterogeneity in AML

Harrison Silva, Grace Martin, Filippo Birocchi, Marc Wehrli, Michael C Kann, Valentina M Supper, Aiyana Parker, Charlotte E Graham, Alexandra Grace Bratt, Amanda A Bouffard, Hannah Donner, Giulia Escobar, Hana N Takei, Alexander Armstrong, Sadie Goncalves, Trisha R Berger, Bryan D. Choi, Marcela V Maus, Mark B Leick
Journal: Blood
Blood blood.2023023210.
https://doi.org/10.1182/blood.2023023210
Published: 2024
Includes: Supplemental data
Journal Articles

Novel CD2-Targeting Trispecific Immune Effector Cell Engager (TRIEC) Coupled with CD19 CAR-T Overcomes Resistant B-Cell Lymphoma

Elijah P Darnell, Hana N Takei, Mark B Leick, Filippo Birocchi, Amanda A Bouffard, Trisha R Berger, Marcela V Maus
Journal: Blood
Blood (2024) 144 (Supplement 1): 2025.
https://doi.org/10.1182/blood-2024-194688
Published: 2024
Journal Articles

A Lenalidomide-Inducible Suicide Switch for Gene- and Cell-Based Therapy

William Lin, Ditsa Sarkar, Joanna Y Kim, Nelson H Knudsen, Isabel C Lane, Andi Cheng, Gabriele Kembaun, Tamina Kienka, Jeannie Carreiro, Amanda A Bouffard, Marcela V Maus, Robert T Manguso, Max Jan
Journal: Blood
Blood (2023) 142 (Supplement 1): 4825.
https://doi.org/10.1182/blood-2023-189628
Published: 2023
Journal Articles

Blocking IFNγ in CAR-T Reduces Checkpoint Inhibitors and Cell-Mediated Toxicity without Compromising Therapeutic Efficacy in CD19 + malignancies

Stefanie R. Bailey, Sonika Vatsa, Rebecca Larson, Amanda A Bouffard, Irene Scarfò, Kathleen M.E. Gallagher, Matthew J. Frigault, Marcela V. Maus
Journal: Blood
Blood (2021) 138 (Supplement 1): 1723.
https://doi.org/10.1182/blood-2021-146042
Published: 2021
Journal Articles

Rational Chemical and Genetic Modifications Enhance Avidity and Function of CD70-Directed CAR-T-Cells for Myeloid Leukemia

Mark B. Leick, Harrison Silva, Irene Scarfò, Rebecca Larson, Bryan D. Choi, Amanda A Bouffard, Kathleen M.E. Gallagher, Andrea Schmidts, Stefanie R. Bailey, Michael C. Kann, Max Jan, Marc Wehrli, Korneel Grauwet, Matthew J. Frigault, Marcela V. Maus
Journal: Blood
Blood (2021) 138 (Supplement 1): 405.
https://doi.org/10.1182/blood-2021-150596
Published: 2021
Journal Articles

Exploiting the Zinc Finger Degrome Targeted By Lenalidomide to Engineer Reversible Off-Switch Degradable Chimeric Antigen Receptors

Max Jan, MD PhD, Ana Castano, MD, Amanda Walker, BA, Andrew A Guirguis, MD PhD, Jessica A Gasser, PhD, Amanda A Bouffard, Mikolaj Slabicki, PhD, Alexander Tepper, Daniel E Grinshpun, Taeyoon Kyung, PhD, Quinlan Sievers, MD PhD, Michael E Birnbaum, PhD, Marcela V Maus, MD PhD, Benjamin L. Ebert, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 866.
https://doi.org/10.1182/blood-2019-124210
Published: 2019
Journal Articles

Use of CD70 Targeted Chimeric Antigen Receptor (CAR) T Cells for the Treatment of Acute Myeloid Leukemia (AML)

Mark Leick, MD, Irene Scarfò, PhD, Bryan D. Choi, MD PhD, Rebecca Larson, BS, Amanda A Bouffard, Ana Castano, MD, Maria L. Cabral, BS, Andrea Schmidts, MD, Matthew J. Frigault, MD, Marcela V. Maus, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4443.
https://doi.org/10.1182/blood-2019-127154
Published: 2019
Journal Articles

Anti-CD37 chimeric antigen receptor T cells are active against B- and T-cell lymphomas

Irene Scarfò, Maria Ormhøj, Matthew J. Frigault, Ana P. Castano, Selena Lorrey, Amanda A. Bouffard, Alexandria van Scoyk, Scott J. Rodig, Alexandra J. Shay, Jon C. Aster, Frederic I. Preffer, David M. Weinstock, Marcela V. Maus
Journal: Blood
Blood (2018) 132 (14): 1495–1506.
https://doi.org/10.1182/blood-2018-04-842708
Published: 2018
Includes: Supplemental data