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María-Victoria Mateos
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Journal Articles

Predictors of unsustained measurable residual disease negativity in transplant-eligible patients with multiple myeloma

Clinical Trials & Observations Brief Report
Camila Guerrero, Noemi Puig, María-Teresa Cedena, María-José Calasanz, Norma C. Gutierrez, Manuela Fernandez, Albert Oriol, Rafael Ríos-Tamayo, Miguel-Teodoro Hernandez, Rafael Martínez-Martínez, Joan Bargay, Felipe de Arriba, Luis Palomera, Ana Pilar Gonzalez-Rodriguez, Marta-Sonia Gonzalez Perez, Alberto Orfao, María-Victoria Mateos, Joaquin Martinez-Lopez, Laura Rosiñol, Joan Bladé, Juan-Jose Lahuerta, Jesus F. San-Miguel, Bruno Paiva
Journal: Blood
Blood (2024) 143 (7): 597–603.
https://doi.org/10.1182/blood.2023022083
Published: 2024
Includes: Supplemental data
Journal Articles

Longitudinal Transcriptomic Analysis of CAR-T Cells at Single-Cell Level Allows the Identification of Molecular Mechanisms Promoting Long-Term CAR-T Cell Persistence in MM

Juan Roberto Rodriguez-Madoz, Lorea Jordana-Urriza, Guillermo Serrano, Aina Oliver-Caldes, Maria Erendira Calleja-Cervantes, Patxi San-Martin, Amaia Vilas-Zornoza, Asier Ullate-Agote, Aintzane Zabaleta, Diego Alignani, Teresa Lozano, Valentin Cabanas Perianes, Juan Luis Reguera, Almudena Navarro-Bailon, Marta Español-Rego, Mariona Pascal, Jose Maria Moraleda, Jose A. Perez-Simon, Maria Victoria Mateos, Fermin Sanchez-Guijo Martin, Alvaro Urbano-Ispizua, Manel Juan, Ana Alfonso Pierola, Jose J. Rifon, Paula Rodriguez Otero, Bruno Paiva, Susana Inogés, Ascensión López-Díaz De Cerio, Juan J Lasarte, Jesús San Miguel, Carlos Fernández de Larrea, Mikel Hernaez, Felipe Prosper
Journal: Blood
Blood (2023) 142 (Supplement 1): 2069.
https://doi.org/10.1182/blood-2023-182933
Published: 2023
Journal Articles

Trial in Progress: A Phase 1 Study of KTX-1001, an Oral, First-in-Class, Selective MMSET Inhibitor in Patients with Relapsed and Refractory Multiple Myeloma

Jesus G. Berdeja, David Dingli, Sagar Lonial, Andrew J. Yee, Alfred Chung, Cristina Gasparetto, P. Leif Bergsagel, Vivek Roy, Al-Ola Abdallah, Sharmilan Thanendrarajan, Aimaz Afrough, Laura Rosiñol, Suzanne Trudel, Paula Rodriguez Otero, Cyrille Touzeau, Pierre Bories, Soo Bang, Terry Connolly, Michelle Kim, Chad A. Lewis, Bao-Van Tran Linberg, M. Travis Quigley, Ola Landgren, Saad Z Usmani, Maria-Victoria Mateos, David S. Siegel
Journal: Blood
Blood (2023) 142 (Supplement 1): 3391.
https://doi.org/10.1182/blood-2023-174550
Published: 2023
Journal Articles

30-Minute Infusion of Isatuximab in Newly Diagnosed Multiple Myeloma (NDMM) Patients: Results of a Phase 1b Study

Enrique M Ocio, Aurore Perrot, Philippe Moreau, Maria-Victoria Mateos, Sara Bringhen, Joaquin Martinez-Lopez, Lionel Karlin, Igor Wolfgang Blau, Song-Yau Wang, Maurizio Martelli, Corina Oprea, Yvonne Dong, Ercem Kodas, Jesus San Miguel
Journal: Blood
Blood (2023) 142 (Supplement 1): 6717.
https://doi.org/10.1182/blood-2023-175020
Published: 2023
Journal Articles

Clinical Significance of Measurable Residual Disease (MRD) in Relapsed/Refractory Multiple Myeloma (RRMM) Patients (Pts) Treated with Chimeric Antigen Receptor (CAR) T Cells and T-Cell Engagers (TCE)

Aintzane Zabaleta, Noemi Puig, Maria Teresa Cedena Romero, Jose J Perez, Cristina Moreno, Luis-Esteban Tamariz-Amador, Paula Rodriguez Otero, Veronica Gonzalez-Calle, Lucia Lopez Corral, Beatriz Rey-Búa, Borja Puertas Martínez, Fatima Miras, Jose Sanchez-Pina, Nieves Lopez, Joaquin Martinez-Lopez, Maria Victoria Mateos, Jesus San-Miguel, Bruno Paiva
Journal: Blood
Blood (2023) 142 (Supplement 1): 94.
https://doi.org/10.1182/blood-2023-185980
Published: 2023
Journal Articles

Kinetics and Biology of Circulating Tumor Cells (CTCs) and Measurable Residual Disease (MRD): Two Dynamic High-Risk Clones in Multiple Myeloma (MM)

Camila Guerrero, Rosalinda Termini, Juan-José Garcés, Maria Jose Calasanz, Rafael Ríos, Elena Cabezudo, Laura Rosiñol, Bargay Joan, Albert Pérez-Montaña, Albert Oriol Rocafiguera, Valentin Cabanas Perianes, Maria-Josefa Najera, Esther Gonzalez Garcia, Enrique M Ocio, Anna Maria Sureda Balari, Felipe De Arriba, Miguel Teodoro Hernández Garcia, Antonio Garcia, Joaquin Martinez-Lopez, María-Jesús Blanchard, Marta Sonia Gonzalez Perez, Rebeca Iglesias, Alberto Orfao, Maria Victoria Mateos, Juan Jose Lahuerta Palacios, Joan Bladé, Jesus San-Miguel, María T Cedena, Noemi Puig, Bruno Paiva
Journal: Blood
Blood (2023) 142 (Supplement 1): 871.
https://doi.org/10.1182/blood-2023-185661
Published: 2023
Journal Articles

Long-Term Outcomes from the Phase 3 OCEAN (OP-103) Study: Melflufen and Dexamethasone (Dex) Versus Pomalidomide (Pom) and Dex in Relapsed Refractory Multiple Myeloma (RRMM)

Fredrik Schjesvold, Meletios A. Dimopoulos, Sosana Delimpasi, Pawel Robak, Daniel Coriu, Wojciech Maciej Legiec, Ludek Pour, Ivan Spicka, Tamas Masszi, Vadim Anatolievich Doronin, Jiri Minarik, Galina Salogub, Yulia Alexeeva, Antonio Lazzaro, Vladimir Maisnar, Gabor Mikala, Stefan Norin, Marcus Thuresson, Anna Bergan, Jakob Obermüller, Roman Hajek, Maria-Victoria Mateos, Paul G. Richardson, Pieter Sonneveld
Journal: Blood
Blood (2023) 142 (Supplement 1): 2018.
https://doi.org/10.1182/blood-2023-177945
Published: 2023
Journal Articles

Analysis of Peripheral Blood and Bone Marrow Residual Disease Dynamics during Intensive Treatment and Maintenance in Patients with Multiple Myeloma Included in the GEM12MENOS65 and GEM14MAIN Clinical Trials

Noemi Puig, Cristina Agullo, Teresa Contreras, Bruno Paiva, María T Cedena, Laura Rosiñol, Ramon Garcia-Sanz, Joaquin Martinez-Lopez, Albert Oriol Rocafiguera, María-Jesús Blanchard, Rafael Ríos, Anna Maria Sureda Balari, Miguel Teodoro Hernández Garcia, Javier De La Rubia, Felipe De Arriba, Luis Palomera, Valentín Cabañas, Maria Belen Inigo Rodriguez, José Juan Pérez, Sergio Castro, Bargay Joan, Joan Bladé, Juan Jose Lahuerta Palacios, Jesús San Miguel, Maria Victoria Mateos
Journal: Blood
Blood (2023) 142 (Supplement 1): 3324.
https://doi.org/10.1182/blood-2023-184837
Published: 2023
Journal Articles

Heterogeneity in Access and Toxicity Management of Commercially Available BCMA-Directed CAR-T and Bispecific T-Cell Engager Therapy Among the International Myeloma Community

Hamza Hassan, Mehmet K. Samur, Adam D. Cohen, Philippe Moreau, Paula Rodríguez Otero, Shaji Kunnathu Kumar, María Victoria Mateos, David Avigan, Adam S. Sperling, Omar Nadeem, Michael Hudecek, Carlos Fernández de Larrea, Joaquin Martínez-López, Maria Themeli, Kwee Yong, Jesus G. Berdeja, Ajai Chari, Pieter Sonneveld, Francesca Gay, Amrita Krishnan, Saad Z Usmani, Kenneth C. Anderson, Sundar Jagannath, Hermann Einsele, Nikhil C Munshi, Shonali Midha
Journal: Blood
Blood (2023) 142 (Supplement 1): 7248.
https://doi.org/10.1182/blood-2023-184710
Published: 2023
Journal Articles

Clinical Outcomes of Subsequent Therapies in Patients with Relapsed/Refractory Multiple Myeloma Following Talquetamab Treatment: Analyses from the Phase 1/2 MonumenTAL-1 Study

Larysa Sanchez, Carolina Schinke, Amrita Krishnan, Jésus G Berdeja, Niels WCJ van de Donk, María Victoria Mateos, Ajai Chari, Samir Parekh, Tarek H. Mouhieddine, Sundar Jagannath, Nizar J Bahlis, Cyrille Touzeau, Albert Oriol, Jesus San-Miguel, Paula Rodriguez Otero, Monique C Minnema, Michela Campagna, Tara J Masterson, Brandi W Hilder, Jaszianne Tolbert, Thomas Renaud, Kathleen Gray, Damiette Smit, Christoph Heuck, Leo Rasche
Journal: Blood
Blood (2023) 142 (Supplement 1): 2007.
https://doi.org/10.1182/blood-2023-182330
Published: 2023
Journal Articles

ARI0002h (Cesnicabtagene Autoleucel), an Academic Point-of-Care B-Cell Maturation Antigen (BCMA)-Directed Chimeric Antigen Receptor (CAR) T-Cell Strategy: Activity and Safety after Fractionated Initial Therapy and Booster Dose in 60 Patients with Relapsed/Refractory Multiple Myeloma

Aina Oliver-Caldes, Veronica Gonzalez-Calle, Valentín Cabañas, Nieves Lopez-Muñoz, Paula Rodriguez Otero, Juan Luis Reguera, Marta Español-Rego, Susana Inoges, Aintzane Zabaleta, Lucia Lopez Corral, Beatriz Martin-Antonio, Lorena Perez-Amill, Bruno Paiva, Laura Rosiñol, Ascensión López-Díaz De Cerio, Sergio Navarro, Joan Cid, Natalia Tovar, Joaquin Saez-Peñataro, Miriam Lopez Parra, Eulalia Olesti, Elena Guillén, Sara Varea, Julio Delgado, Jose Maria Sanchez Pina, Anthony Battram, Marta Sonia Gonzalez Perez, Andres Sanchez Salinas, Valentin Ortiz-Maldonado, Felipe Prosper, Manel Juan, Joaquin Martinez Lopez, Jose Maria Moraleda, Maria Victoria Mateos, Mariona Pascal, Alvaro Urbano-Ispizua, Carlos Fernández de Larrea
Journal: Blood
Blood (2023) 142 (Supplement 1): 1026.
https://doi.org/10.1182/blood-2023-180828
Published: 2023
Journal Articles

Efficacy and Safety of Less Frequent/Lower Intensity Dosing of Talquetamab in Patients with Relapsed/Refractory Multiple Myeloma: Results from the Phase 1/2 MonumenTAL-1 Study

Ajai Chari, Albert Oriol, Amrita Krishnan, Maria Del Carmen Martinez Chamorro, Luciano Costa, Maria Victoria Mateos, Monique C Minnema, Michela Campagna, Tara J Masterson, Brandi W Hilder, Jaszianne Tolbert, Thomas Renaud, M. Damiette Smit, Swarna Ramanjulu, Paula Rodríguez Otero
Journal: Blood
Blood (2023) 142 (Supplement 1): 1010.
https://doi.org/10.1182/blood-2023-181228
Published: 2023
Journal Articles

Renal Sub-Study (GEM-KyCyDex): Cystatin C Improves the Proficiency of Creatinine Alone in the Detection and Management of Myeloma-Related Renal Impairment

Javier Cepeda-Piorno, Borja Puertas Martínez, Laura Rosiñol, Albert Oriol, Felipe De Arriba, Luis Palomera, Miguel Teodoro Hernandez, Jaime Pérez De Oteyza, Ana Pilar Gonzalez, David Carballo, Veronica Gonzalez-Calle, Paula Chavez, Vanesa Garcia-Moreira, Enrique M Ocio, Maria Victoria Mateos, Esther Gonzalez Garcia
Journal: Blood
Blood (2023) 142 (Supplement 1): 4758.
https://doi.org/10.1182/blood-2023-185012
Published: 2023
Journal Articles

Alnuctamab (ALNUC; BMS-986349; CC-93269), a 2+1 B-Cell Maturation Antigen (BCMA) × CD3 T-Cell Engager (TCE), Administered Subcutaneously (SC) in Patients (Pts) with Relapsed/Refractory Multiple Myeloma (RRMM): Updated Results from a Phase 1 First-in-Human Clinical Study

Noffar Bar, Maria Victoria Mateos, Paz Ribas, Markus Hansson, Laura Paris, Craig C. Hofmeister, Paula Rodriguez Otero, Maria Aranzazu Bermúdez, Thomas Martin, Armando Santoro, Andrew J. Yee, Maria Creignou, Cristina Encinas Rodriguez, Claudio Cerchione, Javier De La Rubia, Albert Oriol, Heidi Waibel, Britta Besemer, Ethan Thompson, Brian Kiesel, Jinjie Chen, Alexander Chung, Isaac W. Boss, Allison Gaudy, Shaoyi Li, Kevin Hsu, Colin Godwin, Michael R. Burgess, Jesús San-Miguel, Luciano Costa
Journal: Blood
Blood (2023) 142 (Supplement 1): 2011.
https://doi.org/10.1182/blood-2023-180013
Published: 2023
Journal Articles

Lenalidomide and dexamethasone maintenance with or without ixazomib, tailored by residual disease status in myeloma

Clinical Trials & Observations
Laura Rosiñol, Albert Oriol, Rafael Ríos, María Jesús Blanchard, Isidro Jarque, Joan Bargay, Miguel Teodoro Hernández, Valentín Cabañas, Estrella Carrillo-Cruz, Anna Sureda, Joaquín Martínez-López, Isabel Krsnik, Maria Esther González, Luis Felipe Casado, Josep María Martí, Cristina Encinas, Felipe de Arriba, Luis Palomera, Antonia Sampol, Yolanda González-Montes, Elena Cabezudo, Bruno Paiva, Noemí Puig, María Teresa Cedena, Javier de la Cruz, María-Victoria Mateos, Jesús San Miguel, Juan José Lahuerta, Joan Bladé
Journal: Blood
Blood (2023) 142 (18): 1518–1528.
https://doi.org/10.1182/blood.2022019531
Published: 2023
Journal Articles

Outcomes of Patients with Extramedullary Disease in Triple-Class Exposed Relapsed/Refractory Multiple Myeloma from the LocoMMotion + MoMMent Studies

Philippe Moreau, Maria-Victoria Mateos, Hartmut Goldschmidt, Esther Gonzalez Garcia, Britta Besemer, Marta Sonia Gonzalez Perez, Mohamad Mohty, Joanne Lindsey-Hill, Suriya Kirkpatrick, Michel Delforge, Emanuele Angelucci, Francesco Di Raimondo, Ravi Vij, Margaret Doyle, Kathleen Gray, Claire Albrecht, Vadim Strulev, Imène Haddad, Silva Saarinen, Lada Mitchell, Jozefien Buyze, Katja Weisel
Journal: Blood
Blood (2023) 142 (Supplement 1): 4698.
https://doi.org/10.1182/blood-2023-181235
Published: 2023
Journal Articles

Biological and Clinical Significance of Undetectable Circulating Tumor Cells (CTCs) in Patients (Pts) with Multiple Myeloma (MM)

Juan-José Garcés, Rosalinda Termini, Esperanza Martín-Sánchez, Marta Lasa, Jose J Perez, Norma C. Gutierrez, Manuela Fernández, Maria Jose Calasanz, Laura Rosiñol, Miguel Teodoro Hernández Garcia, Albert Oriol, Anna Maria Sureda Balari, Albert Perez Montaña, Enrique M Ocio, Maria Casanova Espinosa, Felipe Prosper, Joaquin Martinez-Lopez, Jorge Labrador, Esther Gonzalez Garcia, Rafael Ríos, Fernando Escalante, Joan Bargay, Elena Cabezudo, Valentín Cabañas, Niels Weinhold, Aldo Roccaro, Herve Avet-Loiseau, Alberto Orfao, Joan Blade Creixenti, Maria Victoria Mateos, Juan Jose Lahuerta Palacios, Jesus San-Miguel, María T Cedena, Noemi Puig, Bruno Paiva
Journal: Blood
Blood (2023) 142 (Supplement 1): 646.
https://doi.org/10.1182/blood-2023-186411
Published: 2023
Journal Articles

Isolated and Dynamic Peripheral Blood Residual Disease Status Characterized By Mass Spectrometry Predicts Outcome in Patients with High Risk Smoldering Multiple Myeloma Treated in the GEM-CESAR Trial

Noemi Puig, Cristina Agullo, Teresa Contreras, Bruno Paiva, Maria Teresa Cedena Romero, José Juan Pérez, Irene Aires, Joaquin Martinez-Lopez, Paula Rodriguez Otero, Veronica Gonzalez-Calle, Marta Sonia Gonzalez Perez, Norma C. Gutierrez, Albert Oriol Rocafiguera, Rafael Ríos, Laura Rosiñol, Miguel Angel Alvarez Rivas, Maria Jose Calasanz, Bargay Joan, Ramon Garcia-Sanz, Ana Pilar Gonzalez, Adrián Alegre, Fernando Escalante, Rafael Martínez, Javier De La Rubia, Ana Isabel Teruel, Felipe De Arriba, Luis Palomera, Sergio Castro, Miguel Teodoro Hernández Garcia, Javier López, Aránzazu García Mateo, Enrique M Ocio, Joan Bladé, Juan Jose Lahuerta Palacios, Jesús San Miguel, Maria Victoria Mateos
Journal: Blood
Blood (2023) 142 (Supplement 1): 645.
https://doi.org/10.1182/blood-2023-182964
Published: 2023
Journal Articles

Minimally Invasive Assessment of Measurable Residual Disease (MRD) in Multiple Myeloma (MM)

Carmen Gonzalez, Marta Lasa, Laura Notarfranchi, Cristina Agullo, Natalia Buenache Cuenda, Anastasiia Zherniakova, Sergio Castro, José Juan Pérez, Veronica Gonzalez-Calle, Maria Teresa Cedena Romero, Santiago Barrio, Alejandro Martín-Muñoz, Leire Burgos, Diego Alignani, Maria Jose Calasanz, Paula Rodriguez Otero, Laura Rosiñol, Felipe De Arriba, Enrique M Ocio, Albert Oriol Rocafiguera, Luis Palomera, Yolanda González-Montes, Anna Maria Sureda Balari, Miguel Teodoro Hernandez Garcia, Maria Esther Clavero Sanchez, Angela Ibanez Garcia, Clara Gomez, Alberto Orfao, Maria Victoria Mateos, Juan Jose Lahuerta Palacios, Joan Bladé, Jesus San-Miguel, Joaquin Martinez-Lopez, Noemi Puig, Bruno Paiva
Journal: Blood
Blood (2023) 142 (Supplement 1): 339.
https://doi.org/10.1182/blood-2023-186916
Published: 2023
Journal Articles

Symptoms, Functioning, and Health-Related Quality of Life in Patients with Relapsed/Refractory Multiple Myeloma Treated with Talquetamab: Updated Patient-Reported Outcomes from the Phase 1/2 MonumenTAL-1 Study

Carolina Schinke, Cyrille Touzeau, Albert Oriol, María-Victoria Mateos, Don A. Stevens, Leo Rasche, Xiang Qin, Kelly Kato, Timothy Ming, Eva G Katz, Katharine S Gries, Michela Campagna, Tara J Masterson, Brandi W Hilder, Jaszianne Tolbert, Thomas Renaud, Christoph Heuck, Philippe Moreau, Jesús San-Miguel, Paula Rodríguez Otero, Ajai Chari
Journal: Blood
Blood (2023) 142 (Supplement 1): 6711.
https://doi.org/10.1182/blood-2023-189151
Published: 2023