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Journal Articles

Tumor burden quantified by Soluble B-Cell Maturation Antigen and Metabolic Tumor Volume determine myeloma CAR-T outcomes

Ciara L Freeman, Jerald Noble, Meghan Menges, Ricardo Villanueva, Justyn Y Nakashima, Nicholas B Figura, R. Petter Tonseth, Dietrich Werner Idiaquez, Lawrence Skelson, Eric C Smith, Julieta Abraham-Miranda, Salvatore Corallo, Gabriel De Avila, Omar Castaneda Puglianini, Hien D Liu, Melissa Alsina, Taiga Nishihori, Kenneth H Shain, Rachid C Baz, Brandon J Blue, Ariel Grajales-Cruz, John M. Koomen, Reginald M Atkins, Doris K Hansen, Ariosto Siqueira Silva, Jongphil Kim, Yoganand Balagurunathan, Frederick L Locke
Journal: Blood
Blood blood.2024024965.
https://doi.org/10.1182/blood.2024024965
Published: 2024
Includes: Supplemental data
Journal Articles

Outcomes of Teclistamab (Tec) in Patients with Relapsed/Refractory Multiple Myeloma (RRMM) with Prior Exposure to BCMA-Directed Therapy (BCMA-DT): A Multicenter Study from the U.S. Multiple Myeloma Immunotherapy Consortium

Danai Dima, Mariola A Vazquez-Martinez, James A Davis, Utkarsh Goel, Aimaz Afrough, Aishwarya Sannareddy, Oren Pasvolsky, Beatrice Razzo, Rahul Banerjee, Jack Khouri, Ariel Grajales-Cruz, Alex Lieberman-Cribbin, Masooma Shifa Rana, Kelley Julian, Shaun DeJarnette, Andrew J Portuguese, Mahmoud R. Gaballa, Gabriel De Avila, Sandra Susanibar-Adaniya, Shahzad Raza, Megan M Herr, Evguenia Ouchveridze, Tiffany Richards, Hitomi Hosoya, Lekha Mikkilineni, Gurbakhash Kaur, Daniel Schrum, Omar Castaneda, Adriana Rossi, Chenyu Lin, Peter A. Forsberg, Yi Lin, Shebli Atrash, Douglas W Sborov, Kenneth H. Shain, Peter M. Voorhees, Shambavi Richard, Alfred L. Garfall, Doris K. Hansen, Surbhi Sidana, Krina K. Patel, Andrew J. Cowan, Larry D Anderson, Jr., Hans C. Lee, Faiz Anwer, Christopher Ferreri, Leyla O. Shune
Journal: Blood
Blood (2024) 144 (Supplement 1): 897.
https://doi.org/10.1182/blood-2024-203409
Published: 2024
Journal Articles

Comprehensive Analysis of Pre-Treatment Biomarkers Associated with Toxicity and Durable Responses in Idecabtagene Vicleucel Therapy for Relapsed/Refractory Multiple Myeloma

Doris K. Hansen, Ciara Louise Freeman, Meghan Menges, Brett Reid, Julieta Abraham-Miranda, Kayla Reid, Luis Cuadrado Delgado, Gabriel De Avila, Laura B. Oswald, Ariel F. Grajales-Cruz, Brandon Blue, Rebecca Gonzalez, Salvatore Corallo, David R. Noyes, Mark B. Meads, Hien Liu, Taiga Nishihori, Kenneth H. Shain, Rachid Baz, Melissa Alsina, Omar Castaneda, Frederick L. Locke, Lauren C. Peres
Journal: Blood
Blood (2024) 144 (Supplement 1): 896.
https://doi.org/10.1182/blood-2024-197929
Published: 2024
Journal Articles

Pre-Apheresis Prediction of Toxicity and Response in Patients Receiving BCMA-Directed CAR-T for Relapsed/Refractory Multiple Myeloma

Kai Rejeski, Doris K. Hansen, David M. Cordas Dos Santos, Andre De Menezes Silva Corraes, Omar Castaneda, Christen M Dillard, Winfried Alsdorf, Jan H. Frenking, Anna Purcarea, Saurabh Chhabra, Ciara Louise Freeman, Mirco Julian Friedrich, Mahmoud R. Gaballa, Rebecca Gonzalez, Syed Hamza Bin Waqar, Yi Lisa Hwa, Michael D. Jain, Ricardo D. Parrondo, Oren Pasvolsky, Wajma Shahbaz, Roni Shouval, Genevieve Spiess, Haily Stephens, Sebastian Theurich, Florian Bassermann, Judith S. Hecker, Marc S. Raab, Katja C. Weisel, Frederick L. Locke, Marion Subklewe, Krina K. Patel, Yi Lin
Journal: Blood
Blood (2024) 144 (Supplement 1): 895.
https://doi.org/10.1182/blood-2024-208376
Published: 2024
Journal Articles

Comparative Safety and Efficacy of Ciltacabtagene Autoleucel and Idecabtagene Vicleucel CAR T-Cell Therapies in Relapsed or Refractory Multiple Myeloma

Doris K. Hansen, Lauren C. Peres, Danai Dima, Alicia Richards, Leyla O. Shune, Aimaz Afrough, Shonali Midha, Binod Dhakal, Mehmet H. Kocoglu, Shebli Atrash, Chris Ferreri, Omar Castaneda, James A Davis, Evguenia Ouchveridze, Joseph P. McGuirk, Charlotte B Wagner, Radhika Bansal, Patrick Costello, Kinaya Smith, Alex Lieberman-Cribbin, Gabriel De Avila, Sneha Purvey, Hitomi Hosoya, Lekha Mikkilineni, Laura B. Oswald, Gurbakhash Kaur, Oren Pasvolsky, Mahmoud R. Gaballa, Megan M Herr, Peter A. Forsberg, Murali Janakiram, Myo Htut, Sireesha Asoori, Nilesh Kalariya, Hamza Hashmi, Ran Reshef, Douglas W Sborov, Omar Nadeem, Faiz Anwer, Jack Khouri, Shahzad Raza, Djordje Atanackovic, Melissa Alsina, Ciara Louise Freeman, Frederick L. Locke, Peter M. Voorhees, Larry D Anderson, Jr., Shambavi Richard, Thomas Martin, Yi Lin, Krina K. Patel, Surbhi Sidana
Journal: Blood
Blood (2024) 144 (Supplement 1): 936.
https://doi.org/10.1182/blood-2024-194390
Published: 2024
Journal Articles

Outcomes of Elderly Patients with Relapsed Refractory Multiple Myeloma (RRMM) Treated with Teclistamab: A Multicenter Study from the U.S. Multiple Myeloma Immunotherapy Consortium

Oren Pasvolsky, Danai Dima, Lei Feng, Wenli Dong, Tiffany Richards, James A Davis, Aimaz Afrough, Mariola A Vazquez-Martinez, Aishwarya Sannareddy, Utkarsh Goel, Rahul Banerjee, Jack Khouri, Frances N. Cervoni Curet, Mahmoud R. Gaballa, Alex Lieberman-Cribbin, Masooma S Rana, Kelley Julian, Christopher J Ferreri, Leyla O. Shune, Shaun DeJarnette, Evguenia Ouchveridze, Sandra Susanibar-Adaniya, Andrew J. Portuguese, Hitomi Hosoya, Lekha Mikkilineni, Gurbakhash Kaur, Adriana Rossi, Megan M Herr, Daniel Schrum, Chenyu Lin, Shahzad Raza, Yi Lin, Shebli Atrash, Joseph P. McGuirk, Douglas W Sborov, Peter M. Voorhees, Faiz Anwer, Melissa Alsina, Ciara Louise Freeman, Alfred L. Garfall, Surbhi Sidana, Andrew J. Cowan, Larry D Anderson, Jr., Doris K. Hansen, Shambavi Richard, Krina K. Patel, Hans C. Lee, Ariel Grajales-Cruz
Journal: Blood
Blood (2024) 144 (Supplement 1): 934.
https://doi.org/10.1182/blood-2024-205989
Published: 2024
Journal Articles

Genomic Determinants of Resistance to Anti-BCMA Chimeric Antigen Receptor T-Cell (CART) Therapies in Patients with Relapsed/Refractory Multiple Myeloma

Francesco Maura, Ciara Louise Freeman, Holly Lee, Kylee H Maclachlan, Michael Durante, Bachisio Ziccheddu, Meghan Menges, Benjamin Diamond, Marios Papadimitriou, Ariosto Siqueira Silva, Praneeth Reddy Sudalagunta, Noemie Leblay, Sungwoo Ahn, Ethan Fuller, Edward Briercheck, Phaedra Agius, Doris K. Hansen, Xiaofei Song, Xiaohong Zhao, Mark B. Meads, Jamie Teer, Ross S Firestone, Juan-Jose Garces, Tomas Jelinek, Rachid Baz, Melissa Alsina, Anusuyam Ramasubramanian, Eric Smith, Sergio Giralt, Sham Mailankody, Paola Neri, Saad Z. Usmani, Frederick Locke, Nizar J. Bahlis, Ola Landgren, Kenneth H. Shain
Journal: Blood
Blood (2024) 144 (Supplement 1): 247.
https://doi.org/10.1182/blood-2024-201288
Published: 2024
Journal Articles

Talquetamab Bridging: Paving the Way to B-Cell Maturation Antigen (BCMA) CAR-T Cell Therapy in Relapsed/Refractory Multiple Myeloma (RRMM)

Binod Dhakal, Othman S. Akhtar, Andrew J. Cowan, Shambavi Richard, Reed Friend, Matthew J Rees, Patrick Costello, Mariola Vazquez Martinez, Oren Pasvolsky, Charlotte B Wagner, Alexandria Jensen, James A Davis, Ran Reshef, Danai Dima, Rahul Banerjee, Manisha Bhutani, Omar Nadeem, Ricardo D. Parrondo, Lekha Mikkilineni, Shahzad Raza, Prashant Kapoor, Hitomi Hosoya, Saurabh Chhabra, Ariel Grajales-Cruz, Mahmoud R. Gaballa, Shonali Midha, Melissa Alsina, Douglas W. Sborov, Krina K. Patel, Yi Lin, Christopher J Ferreri, Doris K. Hansen, Luciano J. Costa, Surbhi Sidana
Journal: Blood
Blood (2024) 144 (Supplement 1): 931.
https://doi.org/10.1182/blood-2024-202017
Published: 2024
Journal Articles

Efficacy of Stem Cell Boost (SCB) for Chimeric Antigen Receptor T Cell (CAR-T)-Related Hematologic Toxicity in Patients with Relapsed/Refractory Multiple Myeloma (RRMM)- a Multi-Center Real World Experience

Cindy Varga, Myra Robinson, James Davis, Hamza Hashmi, Thomas Martin, Anupama Deepa Kumar, Douglas W Sborov, Charlotte B Wagner, Doris K. Hansen, Omar Castaneda, Leyla O. Shune, Shaun DeJarnette, Aimaz Afrough, Larry D Anderson, Jr., Binod Dhakal, Kinaya Smith, Megan M Herr, Shambavi Richard, Alex Lieberman-Cribbin, Daniel W. Sherbenou, Peter A. Forsberg, Peter M. Voorhees
Journal: Blood
Blood (2024) 144 (Supplement 1): 4712.
https://doi.org/10.1182/blood-2024-204257
Published: 2024
Journal Articles

The Differential Effects of Bridging Therapy on Immune Microenvironment and Outcomes with Idecabtagene-Vicleucel in Multiple Myeloma

Praneeth Reddy Sudalagunta, David R. Noyes, Gabriel De Avila, Alexandra Achille, Rafael Renatino-Canevarolo, Xiaohong Zhao, Maria Silva, Angel Perez, Mark B. Meads, Lauren C. Peres, Doris K. Hansen, Kenneth H. Shain, Ariosto Siqueira Silva
Journal: Blood
Blood (2024) 144 (Supplement 1): 4645.
https://doi.org/10.1182/blood-2024-205631
Published: 2024
Journal Articles

Single-Cell Analysis of CAR-T Cell Products Idecabtagene Vicleucel and Ciltacabtagene Autoleucel Reveals Factors That Influence Clinical Outcomes

Jerald Noble, Xiaofei Song, Meghan Menges, Julieta Abraham-Miranda, Salvatore Corallo, Gabriel De Avila, Omar Puglianini, Hien Liu, Melissa Alsina, Taiga Nishihori, Kenneth H. Shain, Rachid Baz, Brandon Blue, Ariel Grajales-Cruz, Doris K. Hansen, Reginald Atkins, Frederick L. Locke, Ciara Louise Freeman
Journal: Blood
Blood (2024) 144 (Supplement 1): 7173.
https://doi.org/10.1182/blood-2024-208709
Published: 2024
Journal Articles

Safety and Efficacy of Standard of Care (SOC) Elranatamab in Patients with Relapsed/Refractory Multiple Myeloma (RRMM), a Single Center Experience

Ariel F. Grajales-Cruz, Doris K. Hansen, Omar Castaneda, Allison Graeter, Mariola A Vazquez-Martinez, Shrikar Modukuri, Gabriel De Avila, Ariel Denson, Julia Fadul, Brandon Blue, Blanca Lopez, Kristy Harvey, Shrinjaya B Thapa, Katherine Tobon, Parker Melnick, Filip Ionescu, Hien Liu, Jose L. Ochoa-Bayona, Ciara Louise Freeman, Frederick Locke, Taiga Nishihori, Kenneth H. Shain, Melissa Alsina, Rachid Baz
Journal: Blood
Blood (2024) 144 (Supplement 1): 7832.
https://doi.org/10.1182/blood-2024-204276
Published: 2024
Journal Articles

Treatment Patterns and Outcomes in Triple-Class Exposed Patients with Relapsed and Refractory Multiple Myeloma: Findings from the Flatiron Database

Surbhi Sidana, Dhanalakshmi Thirumalai, Taha Itani, Elande Baro, Monique Giordana, Enrique Granados, Ken Hasegawa, Margrit B Rosado, Rebecca J Chan, Ana Kostic, Kamalika Banerjee, Krina K. Patel, Doris K. Hansen
Journal: Blood
Blood (2024) 144 (Supplement 1): 6962.
https://doi.org/10.1182/blood-2024-201119
Published: 2024
Journal Articles

Trajectories of Patient-Reported Outcomes after Idecabtagene Vicleucel Vs. Ciltacabtagene Autoleucel CAR T-Cell Therapy Among Patients with Relapsed/Refractory Multiple Myeloma in Standard of Care

Xiaoyin Li, Carina E. Ferraris, Gabriel De Avila, Lisa M. Gudenkauf, Aasha I. Hoogland, Oanh Nguyen, Yvelise Rodriguez, Sylvia L. Crowder, Nathan Parker, Tiffany L. Carson, Rachid C. Baz, Kenneth H. Shain, Brandon Blue, Ariel Grajales-Cruz, Melissa Alsina, Ciara Louise Freeman, Omar Castaneda, Taiga Nishihori, Hien Liu, Frederick L. Locke, Heather S.L. Jim, Doris K. Hansen, Lauren C. Peres, Laura B. Oswald
Journal: Blood
Blood (2024) 144 (Supplement 1): 7842.
https://doi.org/10.1182/blood-2024-208668
Published: 2024
Journal Articles

Post-CAR-T Driving Restrictions after Week 4 Appear Unnecessary: Data from the United States Myeloma Immunotherapy Consortium

Rahul Banerjee, Alicia Richards, Jack Khouri, Murali Janakiram, Kara I. Cicero, Danai Dima, Mehmet H. Kocoglu, Leyla O. Shune, Evguenia Ouchveridze, Tania Jain, Aimaz Afrough, Saurabh Zanwar, Christopher Ferreri, Oren Pasvolsky, Lekha Mikkilineni, Sneha Purvey, Lauren C. Peres, Ciara Louise Freeman, Shonali Midha, Amer Beitinjaneh, James A Davis, Charlotte B Wagner, Megan M Herr, Peter A. Forsberg, Douglas W. Sborov, Shambavi Richard, Ran Reshef, Binod Dhakal, Veronika Bachanova, Joseph P. McGuirk, Peter M. Voorhees, Larry D Anderson, Jr., Yi Lin, Thomas G Martin, Surbhi Sidana, Krina K. Patel, Doris K. Hansen, Andrew J. Cowan, Gurbakhash Kaur
Journal: Blood
Blood (2024) 144 (Supplement 1): 3765.
https://doi.org/10.1182/blood-2024-199609
Published: 2024
Journal Articles

Patterns of Progression and Outcomes in Multiple Myeloma after Anti-BCMA CAR T-Cell Therapy

Ziad Abuhelwa, Fnu Amisha, Wenyi Fan, Gabriel De Avila, Doris K. Hansen, Ariel F. Grajales-Cruz, Brandon Blue, Omar Castaneda, Hien Liu, Ciara Louise Freeman, Taiga Nishihori, Frederick Locke, Kenneth H. Shain, Rachid Baz, Melissa Alsina
Journal: Blood
Blood (2024) 144 (Supplement 1): 4692.
https://doi.org/10.1182/blood-2024-204270
Published: 2024
Journal Articles

Racial and Ethnic Differences in Outcomes of Multiple Myeloma Patients Treated with Idecabtagene Vicleucel or Ciltacabtagene Autoleucel

Lauren C. Peres, Alicia Richards, Surbhi Sidana, Laura B. Oswald, Danai Dima, Aimaz Afrough, Leyla O. Shune, Shonali Midha, Omar Castaneda, Christopher Ferreri, James A Davis, Oren Pasvolsky, Christen M. Dillard, Megan M Herr, Mehmet H. Kocoglu, Shebli Atrash, Brandon Blue, Evguenia Ouchveridze, Joseph P. McGuirk, Charlotte B Wagner, Radhika Bansal, Patrick Costello, Kinaya Smith, Alex Lieberman-Cribbin, Gabriel De Avila, Sneha Purvey, Hitomi Hosoya, Lekha Mikkilineni, Gurbakhash Kaur, Mahmoud R. Gaballa, Peter A. Forsberg, Ciara Louise Freeman, Murali Janakiram, Myo Htut, Sireesha Asoori, Nilesh Kalariya, Djordje Atanackovic, Binod Dhakal, Jack Khouri, Shahzad Raza, Ran Reshef, Melissa Alsina, Frederick L. Locke, Omar Nadeem, Faiz Anwer, Larry D Anderson, Jr., Shambavi Richard, Yi Lin, Thomas Martin, Peter M. Voorhees, Krina K. Patel, Doris K. Hansen, Douglas W Sborov
Journal: Blood
Blood (2024) 144 (Supplement 1): 3785.
https://doi.org/10.1182/blood-2024-210078
Published: 2024
Journal Articles

Single Center Real World Experience of Talquetamab in Patients with Relapsed and Refractory Multiple Myeloma

Ariel F. Grajales-Cruz, Allison Graeter, Doris K. Hansen, Omar Castaneda, Mariola A Vazquez-Martinez, Shrikar Modukuri, Gabriel De Avila, Ariel Denson, Julia Fadul, Katherine Tobon, Brandon Blue, Blanca Lopez, Kristy Harvey, Parker Melnick, Shrinjaya B Thapa, Filip Ionescu, Hien Liu, Jose L. Ochoa-Bayona, Ciara Louise Freeman, Frederick Locke, Taiga Nishihori, Kenneth H. Shain, Rachid Baz, Melissa Alsina
Journal: Blood
Blood (2024) 144 (Supplement 1): 3784.
https://doi.org/10.1182/blood-2024-204232
Published: 2024
Journal Articles

Predictors and Characterization of Cytokine Release Syndrome (CRS) and Immune Effector Cell-Associated Neurotoxicity Syndrome (ICANS) in Patients with Multiple Myeloma Receiving Teclistamab

Oren Pasvolsky, Aimaz Afrough, Lei Feng, Wenli Dong, Tiffany Richards, James A Davis, Danai Dima, Ariel Grajales-Cruz, Mariola A Vazquez-Martinez, Aishwarya Sannareddy, Utkarsh Goel, Rahul Banerjee, Mahmoud R. Gaballa, Alex Lieberman-Cribbin, Masooma S Rana, Kelley Julian, Christopher J Ferreri, Leyla O. Shune, Shaun DeJarnette, Evguenia Ouchveridze, Sandra Susanibar-Adaniya, Andrew J. Portuguese, Peter A. Forsberg, Hitomi Hosoya, Lekha Mikkilineni, Gurbakhash Kaur, Adriana Rossi, Megan M Herr, Erin Eberwein, Chenyu Lin, Brandon Blue, Shahzad Raza, Yi Lin, Joseph P. McGuirk, Shebli Atrash, Douglas W Sborov, Peter M. Voorhees, Faiz Anwer, Doris K. Hansen, Krina K. Patel, Surbhi Sidana, Andrew J. Cowan, Larry D Anderson, Jr., Shambavi Richard, Alfred L. Garfall, Hans C. Lee, Jack Khouri
Journal: Blood
Blood (2024) 144 (Supplement 1): 3337.
https://doi.org/10.1182/blood-2024-206357
Published: 2024
Journal Articles

Activity and Safety of Venetoclax (VEN)-Based Treatment in t(11;14)-Positive Relapsed/Refractory Multiple Myeloma (R/R MM)

Filip Ionescu, Shrinjaya B Thapa, Parth C Patel, Dimitrios Drekolias, Ariosto Siqueira Silva, Praneeth R Sudalagunta, Phaedra Agius, Brandon Blue, Doris K. Hansen, Omar Castaneda, Hien Liu, Jose L. Ochoa-Bayona, Ciara Louise Freeman, Frederick Locke, Taiga Nishihori, Melissa Alsina, Kenneth H. Shain, Rachid Baz, Ariel Grajales-Cruz
Journal: Blood
Blood (2024) 144 (Supplement 1): 4740.
https://doi.org/10.1182/blood-2024-210069
Published: 2024