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Journal Articles

Predictors of unsustained measurable residual disease negativity in transplant-eligible patients with multiple myeloma

Clinical Trials & Observations Brief Report
Camila Guerrero, Noemi Puig, María-Teresa Cedena, María-José Calasanz, Norma C. Gutierrez, Manuela Fernandez, Albert Oriol, Rafael Ríos-Tamayo, Miguel-Teodoro Hernandez, Rafael Martínez-Martínez, Joan Bargay, Felipe de Arriba, Luis Palomera, Ana Pilar Gonzalez-Rodriguez, Marta-Sonia Gonzalez Perez, Alberto Orfao, María-Victoria Mateos, Joaquin Martinez-Lopez, Laura Rosiñol, Joan Bladé, Juan-Jose Lahuerta, Jesus F. San-Miguel, Bruno Paiva
Journal: Blood
Blood (2024) 143 (7): 597–603.
https://doi.org/10.1182/blood.2023022083
Published: 2024
Includes: Supplemental data
Journal Articles

Definition and Clinical Significance of the MGUS-like Phenotype: A Study in 5,114 Patients (Pts) with Monoclonal Gammopathies

Leire Burgos, Luis Esteban Tamariz-Amador, Noemí Puig, María Teresa Cedena, Tomas Jelinek, Sarah K Johnson, Paolo Milani, Lourdes Cordon, José J Pérez, Marta Lasa, Rosalinda Termini, Albert Oriol, Miguel-Teodoro Hernández, Luis Palomera, Rafael Martinez Martinez, Javier de la Rubia, Felipe De Arriba, Rafael Rios, Maria Esther González, Mercedes Gironella, Valentin Cabañas, Maria Casanova, Isabel Krsnik, Albert Pérez, Veronica Gonzalez De La Calle, Paula Rodríguez-Otero, Vladimir Maisnar, Roman Hajek, Frits van Rhee, Victor H Jimenez-Zepeda, Giovanni Palladini, Paolo Milani, Alberto Orfao, Laura Rosinol, Joan Bladé Creixenti, Joaquín Martínez-López, Juan-José Lahuerta, Maria-Victoria Mateos, Jesús F. San-Miguel, Bruno Paiva
Journal: Blood
Blood (2021) 138 (Supplement 1): 541.
https://doi.org/10.1182/blood-2021-150092
Published: 2021
Journal Articles

Phase 1b Results for Subcutaneous Talquetamab Plus Daratumumab in Patients with Relapsed/Refractory Multiple Myeloma

Ajai Chari, Parameswaran Hari, Nizar J. Bahlis, Maria-Victoria Mateos, Niels W.C.J. van de Donk, Bhagirathbhai Dholaria, Alfred L. Garfall, Hartmut Goldschmidt, K. Martin Kortuem, Amrita Y. Krishnan, Thomas Martin, Daniel Morillo Giles, Albert Oriol, Donna E. Reece, Cesar Rodriguez, Paula Rodriguez-Otero, Jesús F. San-Miguel, Saad Z. Usmani, Raluca I. Verona, Shun Xin Wang Lin, Thomas J. Prior, Mark Wade, Brendan M. Weiss, Jenna D. Goldberg, Elham Askari
Journal: Blood
Blood (2021) 138 (Supplement 1): 161.
https://doi.org/10.1182/blood-2021-148813
Published: 2021
Journal Articles

Severity of Covid-19 Clinical Outcomes and Mortality in Multiple Myeloma Patients over Year 1 of the Pandemic

Joaquín Martínez-López, Maria-Victoria Mateos, Nieves López-Muñoz, Maria Alicia Senin Magan, Maria Dunia De Miguel, Ana López de la Guía, Anna Sureda, Cristina Encinas, Diego Conde Royo, Laura Rosinol, Lucía García Tomás, Jose Angel Hernandez-Rivas, Javier Alberto Rojas, Adrian Alegre, María Jesús Blanchard, Fernando Escalante Barrigón, Esther González Garcia, Belén Iñigo, Pilar Bravo Barahona, F. Javier Penalver, Javier De La Rubia, Noemi Fernandez-Escalada, Jose Maria Alonso Alonso, Joan Bladé, Juan Jose Lahuerta, Javier De La Cruz, Jesús F. San-Miguel
Journal: Blood
Blood (2021) 138 (Supplement 1): 2719.
https://doi.org/10.1182/blood-2021-149192
Published: 2021
Journal Articles

Subsequent Anti-Myeloma Therapy after Idecabtagene Vicleucel (ide-cel, bb2121) Treatment in Patients with Relapsed/Refractory Multiple Myeloma from the KarMMa Study

Paula Rodriguez-Otero, Jesús F. San-Miguel, Larry D. Anderson, Jr., Sagar Lonial, Anna Truppel-Hartmann, Jill Sanford, Everton Rowe, Timothy B. Campbell, Nikhil C. Munshi
Journal: Blood
Blood (2021) 138 (Supplement 1): 2743.
https://doi.org/10.1182/blood-2021-147990
Published: 2021
Journal Articles

Curative Strategy (GEM-CESAR) for High-Risk Smoldering Myeloma (SMM): Carfilzomib, Lenalidomide and Dexamethasone (KRd) As Induction Followed By HDT-ASCT, Consolidation with Krd and Maintenance with Rd

Maria-Victoria Mateos, Joaquin Martinez Lopez, Paula Rodríguez-Otero, Veronica Gonzalez-Calle, Marta Sonia Gonzalez, Albert Oriol, Norma C. Gutierrez, Rafael Rios, Laura Rosinol, Miguel Angel Alvarez, Joan Bargay, Ana Pilar Gonzalez, Adrian Alegre, Fernando Escalante, Belén Iñigo, Javier de la Rubia, Ana Isabel Teruel, Felipe De Arriba, Luis Palomera, Miguel-Teodoro Hernández, Javier Lopez Jimenez, Aránzazu García Mateo, Marta Reinoso Segura, Enrique Ocio, Bruno Paiva, Noemi Puig, María Teresa Cedena, Joan Bladé, Juan Jose Lahuerta, Jesús F. San-Miguel
Journal: Blood
Blood (2021) 138 (Supplement 1): 1829.
https://doi.org/10.1182/blood-2021-148423
Published: 2021
Journal Articles

Baseline Correlates of Complete Response to Idecabtagene Vicleucel (ide-cel, bb2121), a BCMA-Directed CAR T Cell Therapy in Patients with Relapsed and Refractory Multiple Myeloma: Subanalysis of the KarMMa Trial

Nina Shah, Nikhil C. Munshi, Jesús G. Berdeja, Sundar Jagannath, Olivia Finney, Nathan Martin, Amit Agarwal, Everton Rowe, Timothy B. Campbell, Jesús F. San-Miguel
Journal: Blood
Blood (2021) 138 (Supplement 1): 1739.
https://doi.org/10.1182/blood-2021-148375
Published: 2021
Journal Articles

Subcutaneous Teclistamab in Combination with Daratumumab for the Treatment of Patients with Relapsed/Refractory Multiple Myeloma: Results from a Phase 1b Multicohort Study

Paula Rodriguez-Otero, Bhagirathbhai Dholaria, Elham Askari, Donna E. Reece, Niels W.C.J. van de Donk, Ajai Chari, Hartmut Goldschmidt, Amrita Y. Krishnan, Thomas Martin, Maria-Victoria Mateos, Daniel Morillo Giles, Cesar Rodriguez, Laura Rosinol, Jesús F. San-Miguel, Anna Sureda, Ralph Wäsch, Katja Weisel, Raluca I. Verona, Shun Xin Wang Lin, Thomas J. Prior, Brendan M. Weiss, Mark Wade, Jenna D. Goldberg, Albert Oriol, Parameswaran Hari
Journal: Blood
Blood (2021) 138 (Supplement 1): 1647.
https://doi.org/10.1182/blood-2021-148723
Published: 2021
Journal Articles

Selinexor in Combination with Daratumumab-Bortezomib and Dexamethasone for the Treatment of Relapse or Refractory Multiple Myeloma: Initial Results of the Phase 2, Open-Label, Multicenter GEM-Selibordara Study

Paula Rodríguez-Otero, Veronica Gonzalez De La Calle, Anna Sureda, Felipe De Arriba, Marta Reinoso Segura, Paz Ribas, Ana Pilar Gonzalez, Yolanda Gonzalez-Montes, Albert Oriol, Joaquín Martínez-López, Marta Sonia Gonzalez, Miguel T Hernández, Maialen Sirvent, Joan Bladé Creixenti, Juan Jose Lahuerta, Jesús F. San-Miguel, Maria-Victoria Mateos
Journal: Blood
Blood (2021) 138 (Supplement 1): 1677.
https://doi.org/10.1182/blood-2021-147725
Published: 2021
Journal Articles

CAR Density Influences Antitumoral Efficacy of BCMA CAR-T Cells and Correlates with Clinical Outcome

Paula Rodriguez-Marquez, Maria Erendira Calleja-Cervantes, Guillermo Serrano, Maria Luisa Palacios-Berraquero, Diego Alignani, Patxi San Martin-Uriz, Amaia Vilas-Zornoza, Candela Ceballos, Angel Martin-Mallo, Saray Rodríguez-Diaz, Rebeca Martínez-Turrillas, Patricia Jauregui, Cristina Calviño, Susana Inogés, Ascensión López-Diaz de Cerio, Aina Oliver-Caldés, Marta Español-Rego, Mariona Pascal, Beatriz Martin-Antonio, Manel Juan, Álvaro Urbano-Ispizua, Carlos Fernández De Larrea, Maria Cruz Viguria, Ana Margarita Redondo, Paula Rodríguez-Otero, Jose J. Rifon Roca, Ana Alfonso Pierola, Juan Jose Lasarte, Teresa Lozano, Bruno Paiva, Jesús F. San-Miguel, Mikel Hernáez, Juan Roberto Rodriguez-Madoz, Felipe Prósper
Journal: Blood
Blood (2021) 138 (Supplement 1): 735.
https://doi.org/10.1182/blood-2021-148578
Published: 2021
Journal Articles

Tumor cells in light-chain amyloidosis and myeloma show distinct transcriptional rewiring of normal plasma cell development

CME Brief Report
Daniel Alameda, Ibai Goicoechea, Marco Vicari, Elena Arriazu, Alice Nevone, Sara Rodriguez, Marta Lasa, Noemi Puig, Maria Teresa Cedena, Diego Alignani, Sonia Garate, David Lara-Astiaso, Amaia Vilas-Zornoza, Sarai Sarvide, Enrique M. Ocio, Ramon Lecumberri, Alfonso Garcia de Coca, Jorge Labrador, Maria-Esther Gonzalez, Luis Palomera, Mercedes Gironella, Valentin Cabañas, Maria Casanova, Albert Oriol, Isabel Krsnik, Albert Perez-Montaña, Javier de la Rubia, Jose-Enrique de la Puerta, Felipe de Arriba, Vito Michele Fazio, Joaquin Martinez-Lopez, Juan-Jose Lahuerta, Maria-Victoria Mateos, Maria-Dolores Odero, Felipe Prosper, Assaf Weiner, Ido Amit, Mario Nuvolone, Jesus F. San Miguel, Bruno Paiva
Journal: Blood
Blood (2021) 138 (17): 1583–1589.
https://doi.org/10.1182/blood.2020009754
Published: 2021
Includes: Supplemental data
Journal Articles

Updated Phase 1 Results of Teclistamab, a B-Cell Maturation Antigen (BCMA) x CD3 Bispecific Antibody, in Relapsed and/or Refractory Multiple Myeloma (RRMM)

Alfred L. Garfall, MD, Saad Z. Usmani, MDMBBS,MBA, María-Victoria Mateos, Hareth Nahi, MD PhD, Niels W.C.J. van de Donk, MD PhD, Jesus F. San-Miguel, MD PhD, Albert Oriol Rocafiguera, MD, Laura Rosinol, MD PhD, Ajai Chari, MD, Manisha Bhutani, MD, Lixia Pei, PhD, Raluca Verona, PhD, Suzette Girgis, PhD BPharm, MS, Tara Stephenson, PhD, Jenna D. Goldberg, MD, Arnob Banerjee, MD, Amrita Krishnan, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 27.
https://doi.org/10.1182/blood-2020-138831
Published: 2020
Journal Articles

Efficacy and Safety of the Panobinostat-Bortezomib-Dexamethasone Combination in Relapsed or Relapsed/Refractory Multiple Myeloma: Results from the Randomized Panorama 3 Study

Jacob P. Laubach, MD, Fredrik Schjesvold, MDPhD, Mário Mariz, Meletios A Dimopoulos, Ewa Lech-Marańda, MD PhD, Ivan Spicka, MD PhD, Vania T. M. Hungria, MD PhD, Tatiana Shelekhova, Andre Abdo, MD, Lutz Jacobasch, Chantana Polprasert, MD, Roman Hajek, MD PhD, Arpad Illes, MD, Tomasz Wróbel, MD PhD, Anna Sureda Balari, MD PhD, Meral Beksac, MD, Iara Goncalves, Joan Bladé Creixenti, S. Vincent Rajkumar, MD, Ajai Chari, MD, Sagar Lonial, MD FACP, Andrew Spencer, Pierre Maison-Blanche, Philippe Moreau, MD, Paul G. Richardson, MD, Jesus F. San-Miguel, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 4–6.
https://doi.org/10.1182/blood-2020-140697
Published: 2020
Journal Articles

Idecabtagene Vicleucel (ide-cel, bb2121) in Relapsed and Refractory Multiple Myeloma: Analyses of High-Risk Subgroups in the KarMMa Study

Noopur S. Raje, MD, David S. Siegel, MD PhD, Sundar Jagannath, MD, Sagar Lonial, MD FACP, Nikhil C. Munshi, MD, Philippe Moreau, MD, Hartmut Goldschmidt, MD, Michele Cavo, Anna Truppel-Hartmann, MD, Everton Rowe, PhD, Liping Huang, PhD, Amit Agarwal, MD PhD, Julie Wang, PharmD, PhD, Timothy B. Campbell, MD PhD, Jesus F. San-Miguel, MD PhD, Donna E. Reece, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 37–38.
https://doi.org/10.1182/blood-2020-134319
Published: 2020
Journal Articles

Predictive Markers of High-Grade or Serious Treatment-Emergent Infections with Daratumumab-Based Regimens in Newly Diagnosed Multiple Myeloma (NDMM)

Niels W. C. J. van de Donk, Sonja Zweegman, MDPhD, Jesus F. San-Miguel, MD PhD, Meletios A Dimopoulos, Michele Cavo, Kenshi Suzuki, MD PhD, Cyrille Touzeau, Saad Z. Usmani, MDMBBS,MBA, Aurore Perrot, Huiling Pei, PhD, Anupa Kudva, MD, Rian Van Rampelbergh, Jon Ukropec, PhD, Kevin Leary, Robin Carson, MD BA, Ming Qi, MD PhD, Ajai Chari
Journal: Blood
Blood (2020) 136 (Supplement 1): 10–11.
https://doi.org/10.1182/blood-2020-134923
Published: 2020
Journal Articles

Impact of Measurable Residual Disease (MRD) By Multiparameter Flow Cytometry (MFC): A Real-World Study in 1,076 Patients with Acute Myeloid Leukemia (AML)

Bruno Paiva, PhD, María Belén Vidriales, Maria Desamparados Sampere Talens, Fabian Tarin, Enrique Colado, Celina Benavente, María Teresa Cedena, MD, Joaquin Sanchez, MD, Teresa Caballero-Velázquez, MD PhD, Lourdes Cordon, David Martínez-Cuadron, MD, Teresa Bernal del Castillo, MD PhD, Carmen Botella, Sofia Grille, MDPhD, Josefina Serrano, MD, Carlos Rodriguez, Jesús Lorenzo Algarra, Juan Manuel Alonso Dominguez, MD PhD MSc, Maria Luz Amigo, MD, Manuel BARRIOS García, MDPhD, Raimundo García-Boyero, MD, Mercedes Colorado, MD, Jaime Perez De Oteyza, MDPhD, Manuel Perez Encinas, MD, Lissette Del Pilar Costilla, MD, Maria Jose Sayas, Olga Pérez-López, Marcos González, Jose A. Perez-Simon, MD PhD, Joaquin Martinez-Lopez, MD PhD, Claudia Lucia Sossa, Alberto Orfao, MD PhD, Jesús F. San-Miguel, Miguel Sanz, MD PhD, Pau Montesinos, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 13–15.
https://doi.org/10.1182/blood-2020-134349
Published: 2020
Journal Articles

Measurable Residual Disease (MRD) in Elderly Acute Myeloid Leukemia (AML): Results from the Pethema-Flugaza Phase III Clinical Trial

Catia Patricia Simoes, MD, Bruno Paiva, PhD, David Martínez-Cuadron, MD, Juan-Miguel Bergua, MD, Susana Vives, MD, Jesús Lorenzo Algarra, Mar Tormo, MD, Pilar Martinez, MD, Josefina Serrano, MD, Pilar Herrera, MD, Fernando Ramos, MDPhD, Olga Salamero, MD, Esperanza Lavilla, Cristina Gil, Jose Luiz Lopez Lorenzo, MD, Maria-Belen Vidriales, MD, Jorge Labrador, José F. Falantes, Maria Jose Sayas, Rosa Ayala, MD PhD, Joaquin Martinez-Lopez, MD, Sara Villar, María José Calasanz, PhD, Felipe Prosper, MD, Jesús F. San-Miguel, Miguel A. Sanz, Pau Montesinos, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 32.
https://doi.org/10.1182/blood-2020-134651
Published: 2020
Journal Articles

Predictive Biomarkers of Response to Venetoclax in Combination with Cobimetinib in Relapsed/Refractory Multiple Myeloma (RRMM)

Aparna Raval, Habib Hamidi, Olivia Hwang, Cherie Green, Catarina Maia, Marta Lasa, Maika Onishi, Paula Rodriguez-Otero, Jesús F. San-Miguel, Jorge D. Gallo, Bruno Paiva, PhD, Fredrik Schjesvold, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 30–31.
https://doi.org/10.1182/blood-2020-134910
Published: 2020
Journal Articles

Clinical Significance and Biomarkers to Predict Unsustained Complete Remission in Transplant-Eligible Multiple Myeloma

Ana Jimenez-Ubieto, Bruno Paiva, PhD, Joaquin Martinez Lopez, María Teresa Cedena, MD, Noemi Puig, MD PhD, Albert Oriol, MD, Maria Jesús Blanchard, MD, Rafael Rios, MD PhD, Lucia Lopez-Anglada, PhD, Jesús Martín, Rafael Martínez, Anna Sureda Balari, MD PhD, Miguel Hernández, Javier de la Rubia, Isabel Krsnik, MD PhD, Valentin Cabañas, MD, Luis Palomera, MD PhD, Joan Bargay, MD, Jose Maria Moraleda, MD PhD, Laura Rosiñol, María-Victoria Mateos, MD PhD, Jesus F. San-Miguel, MD PhD, Joan Bladé, MD PhD, Juan-José Lahuerta, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 5–6.
https://doi.org/10.1182/blood-2020-136181
Published: 2020
Journal Articles

Clinical Validation of a NGS Capture Panel to Identify Mutations, Copy Number Variations and Translocations in Patients with Multiple Myeloma

Isabel Cuenca, MSc, Alejandro Medina, MD, Laura Rosinol, MD PhD, Iria Vazquez, PhD BSc, Ricardo Sanchez, Norma C. Gutierrez, MD PhD, Yanira Ruiz-Heredia, Santiago Barrio, Albert Oriol, MD, Maria Luisa Martin-Ramos, Manuela Fernández-Guijarro, María Jesús Blanchard, Rafael Rios, MD PhD, Anna Sureda Balari, MD PhD, Miguel T Hernández, Javier de la Rubia, Gorka Alkorta, Xabier Agirre, PhD, Gonzalo R Ordóñez, Rafael Valdés-Mas, Maria-Victoria Mateos, MD PhD, Joan Blade Creixenti, Juan Jose Lahuerta, MD PhD, Jesus F. San-Miguel, MD PhD, Maria Jose Calasanz, PhD BSc, Ramon Garcia-Sanz, Joaquin Martinez-Lopez, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 13–14.
https://doi.org/10.1182/blood-2020-140711
Published: 2020