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Andrea Kühnl
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Journal Articles

Multi-Centre Real-World Outcomes of Large B-Cell Lymphoma Patients Treated with 2L Axicabtagene Ciloleucel in the UK

Andrea Kuhnl, Amy A Kirkwood, Claire Roddie, Caroline Besley, Jane Norman, Ben Uttenthal, Frances Seymour, Andrew J. Davies, Wendy Osborne, William Townsend, Emil Arjun Kumar, Amrith Mathew, Carlos Gonzalez Arias, Ceri Jones, Aikaterini Panopoulou, Ahmed Abdulgawad, Edward Bataillard, Pierre McCarthy, Nicolas Martinez-Calle, Vaishali Dulobdas, Rajesh Alajangi, Ram Malladi, Muddeha Waraich, Olateni Awofisayo, Hwai Jing Hiew, Callum Harris, Michael Northend, Adrian Maraj, Shankaranarayana Paneesha, Kasys Meira-Gervatauskas, Kate Cwynarski, Graham P. Collins, Roderick J. Johnson, Robin Sanderson, Maeve O'Reilly, Tobias Menne, Sridhar Chaganti
Journal: Blood
Blood (2024) 144 (Supplement 1): 2342.
https://doi.org/10.1182/blood-2024-200738
Published: 2024
Journal Articles

Tisagenlecleucel for the Management of Patients with Relapsed/Refractory Diffuse Large B-Cell Lymphoma: An Interim Report of the European Post-Authorisation Safety Study Conducted By EBMT

Silvia Montoto, Jurgen Kuball, Jarl E Mooyaart, Artak Ghandilyan, Dilyana Georgieva, Isabel Sánchez-Ortega, Chiara Bonini, Urban Novak, Dominik Schneidawind, Ibrahim Yakoub-Agha, Jakob Passweg, Sr., Nicolaus Kröger, Christian R Schultze-Florey, Barbara Dreta, Lucia Lopez Corral, Polina Stepensky, Paolo Corradini, Andrea Kuhnl, Stefania Bramanti, Carlos Solano, Ludovic Gabellier, Anja van Biezen, Annalisa Ruggeri, Bertram Glass, Christian Chabannon
Journal: Blood
Blood (2024) 144 (Supplement 1): 607.
https://doi.org/10.1182/blood-2024-200367
Published: 2024
Journal Articles

Prognostication and Treatment-Related Outcomes in Secondary Central Nervous System Involvement of Large B-Cell Lymphoma (SCNSL): Evidence from a Large International Cohort

Juan Pablo Alderuccio, Jahanzaib Khwaja, Sunwoo Han, Paola Ghione, Imran A. Nizamuddin, Aditi Saha, Ning Dong, Yucai Wang, Hua-Jay J Cherng, Seda S. Tolu, Nina Wagner-Johnston, Adam J. Olszewski, Natalie Grover, Jean L. Koff, Amrita Desai, Praveen Ramakrishnan Geethakumari, Tamara K Moyo, Jose Sandoval-Sus, Narendranath Epperla, Danielle S Wallace, Manali Kamdar, Alexey Danilov, Han W. Tun, Javier Munoz, Mayur S. Narkhede, Joanna M. Rhodes, Anca Prica, Andrea Kuhnl, Adrian Maraj, Jessica Okosun, Jeffery Smith, Wendy Osborne, Victoria Calvert, Dima el-Sharkawi, Ammar Hilali, Graham P. Collins, Kim Linton, Nagah Elmusharaf, Anna Santarsieri, Farheen Karim, Thomas Ollila, Sarah Monick, Iris Margalit Trutzer, Nilanjan Ghosh, Jones Can, Amy Ayers, Jacopo Calabrese De Feo, John Sharp, Rachel Treitman, Avyakta Kallam, Izel Okcu, Vismay Deshani, Firas Baidoun, Chathuri Abeyakoon, William Hann, Aisling Barrett, Brad Kahl, Julio C. Chavez, Kate Cwynarski
Journal: Blood
Blood (2024) 144 (Supplement 1): 571.
https://doi.org/10.1182/blood-2024-199781
Published: 2024
Journal Articles

Glofitamab and Epcoritamab in the Real World: A UK Multicentre Retrospective Analysis of Efficacy, Tolerability and Practical Implications

Euan Haynes, Kushani Ediriwickrema, Sarah Lawless, Kevin Joyce, Matthew Wells, Jeffrey Smith, Kim Linton, Anna Santarsieri, George Follows, John Willan, Robert Osborn, Matthew R Wilson, Pamela McKay, Mahina Baloch, Rory McCulloch, Mary Gleeson, David Wrench, David Foldes, Edward Kanfer, Kyaw Zin Maw, Andrea Kuhnl, Matthew Ahearne, Mary Owen, Jane Norman, Ravindu De Silva, Nimish Shah, Harriet Ambrose, Christopher P. Fox, Janine Qasim, Graham P. Collins, Martha Vickers, David Tucker, Li Yuan Chan, Sunil Iyengar, Dima el-Sharkawi, Rebecca Auer, Catherine Cox, Hwai Jing Hiew, Andrew J. Davies, Philippa Kelsey, David John Lewis, Abigail Martin, Gavin Preston, Dominic J. Culligan, Angus Broom, William Wilson, Wendy Osborne, William Townsend
Journal: Blood
Blood (2024) 144 (Supplement 1): 3100.
https://doi.org/10.1182/blood-2024-203781
Published: 2024
Journal Articles

The Post-CAR Prognostic Index (PC-PI): A New Prognostic Score to Predict Overall Survival in Large B-Cell Lymphoma Patients Progressing after Chimeric Antigen Receptor T-Cell Therapy

Gloria Iacoboni, Victor Navarro Garces, Josu Iraola, Pierre Sesques, Kai Rejeski, Fabio Serpenti, Mariana Bastos-Oreiro, ANA Africa Martin Lopez, Javier Delgado, Ariadna Perez, Manuel Guerreiro, Ana Carolina Caballero Gonzalez, Nuria Martinez-Cibrian, Hugo Daniel Luzardo Henriquez, Jose Maria Sanchez Pina, Juan-Manuel Sancho, Herve Ghesquieres, Alberto Mussetti, Pere Barba, Lucia Lopez Corral, Rafael Hernani, Juan Luis Reguera, Anna Maria Sureda Balari, Francesc Bosch, Alejandro Martin Garcia-Sancho, Mi Kwon, Andrea Kuhnl, Marion Subklewe, Emmanuel Bachy, Guillermo Villacampa, Pau Abrisqueta Costa
Journal: Blood
Blood (2023) 142 (Supplement 1): 227.
https://doi.org/10.1182/blood-2023-184942
Published: 2023
Journal Articles

Efficacy of CD19-Directed CAR T Cell Therapy in Patients with Primary or Secondary CNS Lymphoma - an Analysis of the EBMT Lymphoma WP and the Gocart Coalition

Anna Ossami Saidy, Stephan Fuhrmann, Christophe Peczynski, Ariane Boumendil, Eva Michel, Jacques-Emmanuel Galimard, Hervé Finel, Michael Daskalakis, Urban Novak, David Beauvais, Peter Vandenberghe, Nicolaus Kröger, Ron Ram, Jürgen Finke, Matthias Stelljes, Gerald G. Wulf, Wolfgang Andreas Bethge, Malte von Bonin, Gesine Bug, Andrea Kuhnl, Jakob Passweg, Sr., Friedrich Stoelzel, Bastian von Tresckow, Anna Maria Sureda Balari, Peter Dreger, Norbert Schmitz, Bertram Glass
Journal: Blood
Blood (2023) 142 (Supplement 1): 1031.
https://doi.org/10.1182/blood-2023-174883
Published: 2023
Journal Articles

Brexucabtagene Autoleucel for Relapsed/Refractory Mantle Cell Lymphoma: Real-World Outcomes in the United Kingdom

Maeve A O'Reilly, Robin Sanderson, William Wilson, David Burns, Caroline Besley, Thomas Creasey, Ben Uttenthal, Johnathon Elliot, Claire Roddie, Andrea Kuhnl, Shankara Paneesha, Frances Seymour, Sunil Iyengar, Lourdes Rubio, Matthew Wilson, Stephen Boyle, Kathleen PL Cheok, Graham P. Collins, Rod Johnson, Andrew K. McMillan
Journal: Blood
Blood (2022) 140 (Supplement 1): 7519–7521.
https://doi.org/10.1182/blood-2022-165031
Published: 2022
Journal Articles

Improvement in Lymphoma CAR-T Outcomes over Time in the UK - CAR-T Learning Curve or Better Bridging?

Stephen Boyle, Robin Sanderson, Maeve A. O'Reilly, Tobias F. Menne, Jane Norman, Adrian Bloor, Sanne Lugthart, Sridhar Chaganti, Carlos Gonzalez-Arias, Ceri Jones, Anne-Louise Latif, Reuben Benjamin, Piers Patten, Deborah Yallop, Victoria Potter, Claire Roddie, Andrea Kuhnl
Journal: Blood
Blood (2022) 140 (Supplement 1): 4649–4651.
https://doi.org/10.1182/blood-2022-159217
Published: 2022
Journal Articles

CAR-T Toxicity Management and Steroid Use in High-Grade B-Cell Lymphoma: Impact on Real-World Survival Outcomes in the UK

Robin Sanderson, Andrea Kuhnl, Eleni Tholouli, Tobias F Menne, Amit Patel, Sridhar Chaganti, Caroline Besley, Emma Nicholson, Anne-Louise Latif, Ceri Jones, Lourdes Rubio, Charlotte Stenson, Amrith Mathew, Kirsty Sharplin, Jessica Bazin, Lorna Neill, Kathleen Pao Lynn Cheok, Katarzyna Aleksandra Aleksandra Jalowiec, Claire Roddie, Maeve A O'Reilly
Journal: Blood
Blood (2021) 138 (Supplement 1): 531.
https://doi.org/10.1182/blood-2021-149501
Published: 2021
Journal Articles

Real-World Data of High-Grade Lymphoma Patients Treated with CD19 CAR-T in England

Andrea Kuhnl, Claire Roddie, PhD MD, Nuria Martinez-Cibrian, Tobias F Menne, MD PhD FRCPath, Kim Linton, MBChB PhD, Sanne Lugthart, Sridhar Chaganti, MDPhDMRCP,FRCPath, Robin Sanderson, MRCP,FRCPath, Maria A V Marzolini, Jane Norman, MD, Wendy Osborne, MD, John Radford, Stephen Robinson, MBBS, PhD BSc, Ram Malladi, Piers E.M. Patten, BSc, MRCP, MRCPath, PhD, Maeve A O'Reilly, MBBCHBAO, Muhammad Saif, MD, Geoff Shenton, Adrian Bloor, FRCPath, Clare J Rowntree, MBBS, PhD FRCP, FRCPath, David A. Irvine, BSc, MBBChir, MRCP, FRCPath, PhD, Orla Stewart, Arzhang Ardavan, Kate Robinson, Antonio Pagliuca, MBBS, MA, FRCP, FRCPath, Kristian M Bowles, MBBS, PhD, Graham P. Collins, MA, MBBS, MRCP, FRCPath, DPhil, Rod Johnson, Andrew K McMillan, FRCP
Journal: Blood
Blood (2019) 134 (Supplement_1): 767.
https://doi.org/10.1182/blood-2019-124177
Published: 2019
Journal Articles

Durable Remissions Achieved with R-CHOP Chemotherapy without Radiotherapy in Patients with Primary Mediastinal B-Cell Lymphoma - the Royal Marsden Experience

Vasiliki Michalarea, MD, Dima El-Sharkawi, MBBS BSc FRCPath MD, Siraj Yusuf, Mary Gleeson, Laura Hickmott, Andrew Wotherspoon, Ayoma Attygalle, Simon O'Connor, Bhupinder Sharma, Yong Du, Imene Zerizer, Alan Horwich, Gillian Ross, Andrea Kuhnl, Sunil Iyengar, Ian Chau, MD, David Cunningham
Journal: Blood
Blood (2018) 132 (Supplement 1): 4240.
https://doi.org/10.1182/blood-2018-99-119560
Published: 2018
Journal Articles

Diffuse Large B-Cell Lymphoma Remodels the Fibroblastic Reticular Network That Acquires Aberrant Immunosuppressive Capabilities; Implications for the Regulation of Anti-Tumor Immunity in the Immuno-Oncology Era

Benedetta Apollonio, PhD, Peter Jarvis, MSc, Beth Phillips, MBBS, FRCPath, BSc, Andrea Kuhnl, Jon Salisbury, Georgios Zacharioudakis, Lesley-Ann Sutton, Richard Rosenquist, MD PhD, Ruth Jarrett, MBBChir, FRCPath, FRCP, Rose-Marie Amini, Anna Vardi, MD PhD, Alan G. Ramsay, BSc,MSc,PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 675.
https://doi.org/10.1182/blood-2018-99-116409
Published: 2018
Journal Articles

R-GEM-Lenalidomide Versus R-GEM-P As Second-Line Treatment of Diffuse Large B-Cell Lymphoma: Results from the UK NCRI Phase II Randomized Legend Trial

Andrea Kuhnl, MD, Clare Peckitt, Bijal Patel, Kirit M Ardeshna, MD, Marian P Macheta, John Radford, MD, Rod Johnson, Shankaranarayana Paneesha, Sarah Barton, Ian Chau, MD, Martin F Kaiser, MD, Ruwaida Begum, Nicola Valeri, Andrew Wotherspoon, Yong Du, Imene Zerizer, David Cunningham, MD FRCP
Journal: Blood
Blood (2017) 130 (Supplement 1): 2829.
https://doi.org/10.1182/blood.V130.Suppl_1.2829.2829
Published: 2017
Journal Articles

Genome-Wide Methylation Analysis of Patients with Diffuse Large B Cell Lymphoma Treated on the UK NCRI R-CHOP 14 Vs 21 Trial

Andrea Kühnl, MD, Ridwan Shaikh, David Cunningham, Sharon L Barrans, Cathy H Burton, Andrew Jack, Mary Gleeson, Nicholas Counsell, Paul Smith, Oliver Schofield, David C. Linch, FRCP, Michael Hubank, PhD
Journal: Blood
Blood (2016) 128 (22): 1747.
https://doi.org/10.1182/blood.V128.22.1747.1747
Published: 2016
Journal Articles

Outcome of Elderly Patients with Diffuse Large B-Cell Lymphoma Treated with R-CHOP: Subgroup Analysis from the UK NCRI R-CHOP 14 Vs 21 Trial

Andrea Kühnl, MD, David Cunningham, Nicholas Counsell, Eliza A Hawkes, Wendi Qian, PhD, Paul Smith, Nick Chadwick, Anthony Lawrie, Paul Mouncey, Andrew S Jack, Christopher Pocock, Kirit Ardeshna, MD, John Radford, Andrew McMillan, PhD, John Davies, Deborah Turner, Anton Kruger, Peter W Johnson, MD, Joanna Gambell, David C Linch, FMedSci
Journal: Blood
Blood (2015) 126 (23): 1516.
https://doi.org/10.1182/blood.V126.23.1516.1516
Published: 2015
Journal Articles

Downregulation of the Wnt inhibitor CXXC5 predicts a better prognosis in acute myeloid leukemia

Clinical Trials & Observations
Andrea Kühnl, Peter J. M. Valk, Mathijs A. Sanders, Adam Ivey, Robert K. Hills, Ken I. Mills, Rosemary E. Gale, Martin F. Kaiser, Richard Dillon, Melanie Joannides, Amanda Gilkes, Torsten Haferlach, Susanne Schnittger, Estelle Duprez, David C. Linch, Ruud Delwel, Bob Löwenberg, Claudia D. Baldus, Ellen Solomon, Alan K. Burnett, David Grimwade
Journal: Blood
Blood (2015) 125 (19): 2985–2994.
https://doi.org/10.1182/blood-2014-12-613703
Published: 2015
Includes: Supplemental data
Journal Articles

Downregulation Of The Wnt Inhibitor CXXC5 Predicts a Better Prognosis In Acute Myeloid Leukemia

Andrea Kühnl, Peter J. M. Valk, Mathijs A. Sanders, Robert K. Hills, MA, MSc, DPhil, Ken I. Mills, PhD, Rosemary E Gale, PhD, Martin Kaiser, MD, Richard Dillon, Melanie Joannides, Adam Ivey, Amanda F Gilkes, MSc, Torsten Haferlach, MD, Susanne Schnittger, PhD, Estelle Duprez, David Linch, FMedSci, Ruud Delwel, Bob Löwenberg, MD, PhD, Claudia D. Baldus, MD, PhD, Ellen Solomon, Alan K Burnett, MD, David Grimwade, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 52.
https://doi.org/10.1182/blood.V122.21.52.52
Published: 2013
Journal Articles

Overexpression of LEF1 predicts unfavorable outcome in adult patients with B-precursor acute lymphoblastic leukemia

Clinical Trials & Observations
Andrea Kühnl, Nicola Gökbuget, Martin Kaiser, Cornelia Schlee, Andrea Stroux, Thomas Burmeister, Liliana H. Mochmann, Dieter Hoelzer, Wolf-Karsten Hofmann, Eckhard Thiel, Claudia D. Baldus
Journal: Blood
Blood (2011) 118 (24): 6362–6367.
https://doi.org/10.1182/blood-2011-04-350850
Published: 2011
Journal Articles

High BAALC expression predicts chemoresistance in adult B-precursor acute lymphoblastic leukemia

Andrea Kühnl, Nicola Gökbuget, Andrea Stroux, Thomas Burmeister, Martin Neumann, Sandra Heesch, Torsten Haferlach, Dieter Hoelzer, Wolf-Karsten Hofmann, Eckhard Thiel, Claudia D. Baldus
Journal: Blood
Blood (2010) 115 (18): 3737–3744.
https://doi.org/10.1182/blood-2009-09-241943
Published: 2010