Bob Löwenberg,for the Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK),Thomas Pabst,for the Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK),Johan Maertens,for the Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK),Yvette van Norden,for the Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK),Bart J. Biemond,for the Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK),Harry C. Schouten,for the Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK),Olivier Spertini,for the Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK),Edo Vellenga,for the Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK),Carlos Graux,for the Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK),Violaine Havelange,for the Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK),Georgine E. de Greef,for the Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK),Okke de Weerdt,for the Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK),Marie-Cecile J. C. Legdeur,for the Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK),Juergen Kuball,for the Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK),Marinus van Marwijk Kooy,for the Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK),Bjorn T. Gjertsen,for the Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK),Mojca Jongen-Lavrencic,for the Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK),Arjan A. van de Loosdrecht,for the Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK),Daniëlle van Lammeren-Venema,for the Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK),Beata Hodossy,for the Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK),Dimitri A. Breems,for the Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK),Yves Chalandon,for the Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK),Jakob Passweg,for the Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK),Peter J. M. Valk,for the Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK),Markus G. Manz,for the Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK),Gert J. Ossenkoppele,for the Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON) and Swiss Group for Clinical Cancer Research (SAKK)

View Articletitled, Therapeutic value of clofarabine in younger and middle-aged (18-65 years) adults with newly diagnosed AML

Supplemental data

International, evidence-based consensus diagnostic criteria for HHV-8–negative/idiopathic multicentric Castleman disease
Clinical Trials & Observations

David C. Fajgenbaum,Thomas S. Uldrick,Adam Bagg,Dale Frank,David Wu,Gordan Srkalovic,David Simpson,Amy Y. Liu,David Menke,Shanmuganathan Chandrakasan,Mary Jo Lechowicz,Raymond S. M. Wong,Sheila Pierson,Michele Paessler,Jean-François Rossi,Makoto Ide,Jason Ruth,Michael Croglio,Alexander Suarez,Vera Krymskaya,Amy Chadburn,Gisele Colleoni,Sunita Nasta,Raj Jayanthan,Christopher S. Nabel,Corey Casper,Angela Dispenzieri,Alexander Fosså,Dermot Kelleher,Razelle Kurzrock,Peter Voorhees,Ahmet Dogan,Kazuyuki Yoshizaki,Frits van Rhee,Eric Oksenhendler,Elaine S. Jaffe,Kojo S. J. Elenitoba-Johnson,Megan S. Lim

View Articletitled, International, evidence-based consensus diagnostic criteria for HHV-8–negative/idiopathic multicentric Castleman disease

Clinical and pathological characteristics of HIV- and HHV-8–negative Castleman disease
Clinical Trials & Observations

Li Yu,Meifeng Tu,Jorge Cortes,Zijun Y. Xu-Monette,Roberto N. Miranda,Jun Zhang,Robert Z. Orlowski,Sattva Neelapu,Prajwal C. Boddu,Mary A. Akosile,Thomas S. Uldrick,Robert Yarchoan,L. Jeffrey Medeiros,Yong Li,David C. Fajgenbaum,Ken H. Young

View Articletitled, Clinical and pathological characteristics of HIV- and HHV-8–negative Castleman disease

IMMUNOBIOLOGY

Platelets activate a pathogenic response to blood-stage Plasmodium infection but not a protective immune response

Irene Gramaglia,Joyce Velez,Valery Combes,Georges E. R. Grau,Melanie Wree,Henri C. van der Heyde

View Articletitled, Platelets activate a pathogenic response to blood-stage Plasmodium infection but not a protective immune response

Supplemental data

LYMPHOID NEOPLASIA

In utero cytomegalovirus infection and development of childhood acute lymphoblastic leukemia
Clinical Trials & Observations Brief Report

Stephen Starko Francis,Amelia D. Wallace,George A. Wendt,Linlin Li,Fenyong Liu,Lee W. Riley,Scott Kogan,Kyle M. Walsh,Adam J. de Smith,Gary V. Dahl,Xiaomei Ma,Eric Delwart,Catherine Metayer,Joseph L. Wiemels

View Articletitled, In utero cytomegalovirus infection and development of childhood acute lymphoblastic leukemia

Supplemental data

MYELOID NEOPLASIA

Molecular disease monitoring using circulating tumor DNA in myelodysplastic syndromes
Clinical Trials & Observations Brief Report

Paul Yeh,Michael Dickinson,Sarah Ftouni,Tane Hunter,Devbarna Sinha,Stephen Q. Wong,Rishu Agarwal,Ravikiran Vedururu,Kenneth Doig,Chun Yew Fong,Piers Blombery,David Westerman,Mark A. Dawson,Sarah-Jane Dawson

View Articletitled, Molecular disease monitoring using circulating tumor DNA in myelodysplastic syndromes

Supplemental data

PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS

CSF-1–induced Src signaling can instruct monocytic lineage choice

Max Endele,Dirk Loeffler,Konstantinos D. Kokkaliaris,Oliver Hilsenbeck,Stavroula Skylaki,Philipp S. Hoppe,Axel Schambach,E. Richard Stanley,Timm Schroeder

View Articletitled, CSF-1–induced Src signaling can instruct monocytic lineage choice

Supplemental data

PLATELETS AND THROMBOPOIESIS

Platelet secretion is crucial to prevent bleeding in the ischemic brain but not in the inflamed skin or lung in mice
Brief Report

Carsten Deppermann,Peter Kraft,Julia Volz,Michael K. Schuhmann,Sarah Beck,Karen Wolf,David Stegner,Guido Stoll,Bernhard Nieswandt

View Articletitled, Platelet secretion is crucial to prevent bleeding in the ischemic brain but not in the inflamed skin or lung in mice

Supplemental data

THROMBOSIS AND HEMOSTASIS

Polyphosphate nanoparticles on the platelet surface trigger contact system activation

Johan J. F. Verhoef,Arjan D. Barendrecht,Katrin F. Nickel,Kim Dijkxhoorn,Ellinor Kenne,Linda Labberton,Owen J. T. McCarty,Raymond Schiffelers,Harry F. Heijnen,Antoni P. Hendrickx,Huub Schellekens,Marcel H. Fens,Steven de Maat,Thomas Renné,Coen Maas

View Articletitled, Polyphosphate nanoparticles on the platelet surface trigger contact system activation

Supplemental data

TRANSPLANTATION

Tolerogenic interactions between CD8⁺ dendritic cells and NKT cells prevent rejection of bone marrow and organ grafts

David Hongo,Xiaobin Tang,Xiangyue Zhang,Edgar G. Engleman,Samuel Strober

View Articletitled, Tolerogenic interactions between CD8+ dendritic cells and NKT cells prevent rejection of bone marrow and organ grafts

Supplemental data

LETTERS TO BLOOD

KMT2E-ASNS: a novel relapse-specific fusion gene in early T-cell precursor acute lymphoblastic leukemia

Fida Khater,Mathieu Lajoie,Sylvie Langlois,Jasmine Healy,Sonia Cellot,Chantal Richer,Patrick Beaulieu,Pascal St-Onge,Virginie Saillour,Mark Minden,Monia Marzouki,Maja Krajinovic,Henrique Bittencourt,Daniel Sinnett

View Articletitled, KMT2E-ASNS: a novel relapse-specific fusion gene in early T-cell precursor acute lymphoblastic leukemia

Supplemental data

Platelet CD34 expression and α/δ-granule abnormalities in GFI1B- and RUNX1-related familial bleeding disorders

Anna E. Marneth,Waander L. van Heerde,Konnie M. Hebeda,Britta A. P. Laros-van Gorkom,Wideke Barteling,Brigith Willemsen,Aniek O. de Graaf,Annet Simons,Joop H. Jansen,Frank Preijers,Marjolijn C. Jongmans,Bert A. van der Reijden

View Articletitled, Platelet CD34 expression and α/δ-granule abnormalities in GFI1B- and RUNX1-related familial bleeding disorders

Supplemental data

BLOOD WORK

A case of bad Carma!

David Buchbinder,Aaron Sassoon

View Articletitled, A case of bad Carma!

Cover Image

Cover Image

Incorporation of polyphosphate nanoparticles into platelet aggregates. The image shows a cross-section of platelet aggregates (bright-field microscopy; 2.9 μm from the surface), formed by flowing citrated whole blood over immobilized collagen at a shear rate of 1600 s⁻¹ for 10 minutes. Extracellular platelet polyphosphate was simultaneously visualized by fluorescence microscopy with SYTOX (orange). See the article by Verhoef et al on page 1707.
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Issue Archive

Table of Contents

EDITORIAL

INSIDE BLOOD COMMENTARIES

Multicentric Castleman disease: consensus at last? Clinical Trials & Observations

Unraveling Castleman: progress in a complex process Clinical Trials & Observations

REVIEW SERIES

CLINICAL TRIALS AND OBSERVATIONS

Therapeutic value of clofarabine in younger and middle-aged (18-65 years) adults with newly diagnosed AML Clinical Trials & Observations

International, evidence-based consensus diagnostic criteria for HHV-8–negative/idiopathic multicentric Castleman disease Clinical Trials & Observations

Clinical and pathological characteristics of HIV- and HHV-8–negative Castleman disease Clinical Trials & Observations

IMMUNOBIOLOGY

LYMPHOID NEOPLASIA

In utero cytomegalovirus infection and development of childhood acute lymphoblastic leukemia Clinical Trials & Observations Brief Report

MYELOID NEOPLASIA

Molecular disease monitoring using circulating tumor DNA in myelodysplastic syndromes Clinical Trials & Observations Brief Report

PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS

PLATELETS AND THROMBOPOIESIS

Platelet secretion is crucial to prevent bleeding in the ischemic brain but not in the inflamed skin or lung in mice Brief Report

THROMBOSIS AND HEMOSTASIS

TRANSPLANTATION

LETTERS TO BLOOD

BLOOD WORK

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ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only

Multicentric Castleman disease: consensus at last?
Clinical Trials & Observations

Unraveling Castleman: progress in a complex process
Clinical Trials & Observations

Therapeutic value of clofarabine in younger and middle-aged (18-65 years) adults with newly diagnosed AML
Clinical Trials & Observations

International, evidence-based consensus diagnostic criteria for HHV-8–negative/idiopathic multicentric Castleman disease
Clinical Trials & Observations

Clinical and pathological characteristics of HIV- and HHV-8–negative Castleman disease
Clinical Trials & Observations

In utero cytomegalovirus infection and development of childhood acute lymphoblastic leukemia
Clinical Trials & Observations Brief Report

Molecular disease monitoring using circulating tumor DNA in myelodysplastic syndromes
Clinical Trials & Observations Brief Report

Platelet secretion is crucial to prevent bleeding in the ischemic brain but not in the inflamed skin or lung in mice
Brief Report