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David Vetrie
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Journal Articles

Leukaemia Exposure Alters the Transcriptional Profile and Function of Macrophages in the Bone Marrow Niche

Martha M. Zarou, Amy Dawson, Bodhayan Prasad, Joana Bittencourt-Silvestre, Désirée Zerbst, Giovanny Rodriguez Blanco, Mary Scott, Karen Dunn, Vaidehi Krishnan, Mhairi Copland, David Vetrie, Ravi Bhatia, Seth Coffelt, S.Tiong Ong, Helen Wheadon, Sara Zanivan, Kristina Kirschner, G. Vignir Helgason
Journal: Blood
Blood (2023) 142 (Supplement 1): 2704.
https://doi.org/10.1182/blood-2023-181630
Published: 2023
Journal Articles

Uncoupling p53 from an Embryonic Regulome Exhausts Quiescent CML Stem Cells through Inhibition of a HIF1alpha Molecular Program

Mary T Scott, Wei Liu, Rebecca Mitchell, Cassie Clarke, Hassan Almasoudi, Felix Warren, Ross Kinstrie, Karen Dunn, John Pritchard, Mark E Drotar, Alison M Michie, Heather G Jørgensen, Brian Higgins, Mhairi Copland, David Vetrie
Journal: Blood
Blood (2021) 138 (Supplement 1): 1541.
https://doi.org/10.1182/blood-2021-150372
Published: 2021
Journal Articles

The Histone Demethylase KDM4A Is Required to Sustain H3K9me3/H3K27me3 Epigenetic States and Oncogenesis in MLL-AF9 Acute Myeloid Leukemia

Matthew E Massett, BSc, Niamh Mannion, BSc,PhD, Laura Monaghan, BSc, Joana Bittencourt-Silvestre, BSc, MSc, Sandra Marmiroli, BSc,PhD, Robert M J Liskamp, BSc, PhD, Alison M Michie, BSc, PhD, David Vetrie, BSc, PhD, Xu Huang, BSc, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3879.
https://doi.org/10.1182/blood-2018-99-111256
Published: 2018
Journal Articles

The chronic myeloid leukemia stem cell: stemming the tide of persistence

Tessa L. Holyoake, David Vetrie
Journal: Blood
Blood (2017) 129 (12): 1595–1606.
https://doi.org/10.1182/blood-2016-09-696013
Published: 2017
Journal Articles

CML cells actively evade host immune surveillance through cytokine-mediated downregulation of MHC-II expression

Anuradha Tarafdar, Lisa E. M. Hopcroft, Paolo Gallipoli, Francesca Pellicano, Jennifer Cassels, Alan Hair, Koorosh Korfi, Heather G. Jørgensen, David Vetrie, Tessa L. Holyoake, Alison M. Michie
Journal: Blood
Blood (2017) 129 (2): 199–208.
https://doi.org/10.1182/blood-2016-09-742049
Published: 2017
Includes: Supplemental data
Journal Articles

Notch Pathway Activation Targets Leukemic Stem Cells in Chronic-Phase Chronic Myeloid Leukemia (CP-CML)

Gillian A. Horne, BSc hons, MBChB, MRCP, MRes, Heather Morrison, BSc hons, Victoria Campbell, BSc hons, MBBS, MRCP, FRCPath, Ross Kinstrie, PhD BSc, Jennifer Cassels, BSc hons, Alan Hair, BSc, PhD, David Vetrie, BSc, PhD, Helen Wheadon, PhD, Tessa L. Holyoake, MD PhD FRCP, FRCPath, Mhairi Copland, BSc (Hons) MB ChB PhDFRCP FRCPath
Journal: Blood
Blood (2016) 128 (22): 3057.
https://doi.org/10.1182/blood.V128.22.3057.3057
Published: 2016
Journal Articles

Chromatin looping defines expression of TAL1 , its flanking genes, and regulation in T-ALL

Yan Zhou, Sreenivasulu Kurukuti, Peter Saffrey, Milica Vukovic, Alison M. Michie, Ruslan Strogantsev, Adam G. West, David Vetrie
Journal: Blood
Blood (2013) 122 (26): 4199–4209.
https://doi.org/10.1182/blood-2013-02-483875
Published: 2013
Includes: Supplemental data
Journal Articles

Misregulation Of The PRC2 Complex In CML Stem Cells Confers Sensitivity To An EZH2 Inhibitor

Mary T Scott, PhD, Koorosh Korfi, PhD, Paolo Gallipoli, PhD, Peter Saffrey, PhD, Heather Jorgensen, PhD, Michelle Cruz, Ashley Hamilton, PhD, Amy Sinclair, Andrew Crossan, PhD, Emmanuel Normant, PhD, Vidya Balasubramanian, Tessa L. Holyoake, PhD, David Vetrie, PhD
Journal: Blood
Blood (2013) 122 (21): 2710.
https://doi.org/10.1182/blood.V122.21.2710.2710
Published: 2013