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Old variables, new value: a refined IPI for DLBCL
Ph+ ALL: imatinib grows older with patients
An enhanced International Prognostic Index (NCCN-IPI) for patients with diffuse large B-cell lymphoma treated in the rituximab era
UKALLXII/ECOG2993: addition of imatinib to a standard treatment regimen enhances long-term outcomes in Philadelphia positive acute lymphoblastic leukemia
Issue Archive
Table of Contents
INSIDE BLOOD
CLINICAL TRIALS & OBSERVATIONS
Old variables, new value: a refined IPI for DLBCL
Clinical Trials & Observations
CLINICAL TRIALS & OBSERVATIONS
Ph+ ALL: imatinib grows older with patients
Clinical Trials & Observations
BLOOD WORK
PLENARY PAPER
GATA2 deficiency: a protean disorder of hematopoiesis, lymphatics, and immunity
Michael A. Spinner,Lauren A. Sanchez,Amy P. Hsu,Pamela A. Shaw,Christa S. Zerbe,Katherine R. Calvo,Diane C. Arthur,Wenjuan Gu,Christine M. Gould,Carmen C. Brewer,Edward W. Cowen,Alexandra F. Freeman,Kenneth N. Olivier,Gulbu Uzel,Adrian M. Zelazny,Janine R. Daub,Christine D. Spalding,Reginald J. Claypool,Neelam K. Giri,Blanche P. Alter,Emily M. Mace,Jordan S. Orange,Jennifer Cuellar-Rodriguez,Dennis D. Hickstein,Steven M. Holland
EVIDENCE-BASED FOCUSED REVIEW
Meta-analysis of low-molecular-weight heparin to prevent recurrent placenta-mediated pregnancy complications
Marc A. Rodger,Marc Carrier,Grégoire Le Gal,Ida Martinelli,Annalisa Perna,Évelyne Rey,J. I. P. de Vries,Jean-Christophe Gris,on behalf of the Low-Molecular-Weight Heparin for Placenta-Mediated Pregnancy Complications Study Group
HOW I TREAT
CLINICAL TRIALS AND OBSERVATIONS
An enhanced International Prognostic Index (NCCN-IPI) for patients with diffuse large B-cell lymphoma treated in the rituximab era
Clinical Trials & Observations
Zheng Zhou,Laurie H. Sehn,Alfred W. Rademaker,Leo I. Gordon,Ann S. LaCasce,Allison Crosby-Thompson,Ann Vanderplas,Andrew D. Zelenetz,Gregory A. Abel,Maria A. Rodriguez,Auayporn Nademanee,Mark S. Kaminski,Myron S. Czuczman,Michael Millenson,Joyce Niland,Randy D. Gascoyne,Joseph M. Connors,Jonathan W. Friedberg,Jane N. Winter
UKALLXII/ECOG2993: addition of imatinib to a standard treatment regimen enhances long-term outcomes in Philadelphia positive acute lymphoblastic leukemia
Clinical Trials & Observations
Adele K. Fielding,Jacob M. Rowe,Georgina Buck,Letizia Foroni,Gareth Gerrard,Mark R. Litzow,Hillard Lazarus,Selina M. Luger,David I. Marks,Andrew K. McMillan,Anthony V. Moorman,Bella Patel,Elisabeth Paietta,Martin S. Tallman,Anthony H. Goldstone
HEMATOPOIESIS AND STEM CELLS
The evolution of cellular deficiency in GATA2 mutation
Rachel E. Dickinson,Paul Milne,Laura Jardine,Sasan Zandi,Sabina I. Swierczek,Naomi McGovern,Sharon Cookson,Zaveyna Ferozepurwalla,Alexander Langridge,Sarah Pagan,Andrew Gennery,Tarja Heiskanen-Kosma,Sari Hämäläinen,Mikko Seppänen,Matthew Helbert,Eleni Tholouli,Eleonora Gambineri,Sigrún Reykdal,Magnús Gottfreðsson,James E. Thaventhiran,Emma Morris,Gideon Hirschfield,Alex G. Richter,Stephen Jolles,Chris M. Bacon,Sophie Hambleton,Muzlifah Haniffa,Yenan Bryceson,Carl Allen,Josef T. Prchal,John E. Dick,Venetia Bigley,Matthew Collin
LYMPHOID NEOPLASIA
Lyn-mediated procaspase 8 dimerization blocks apoptotic signaling in B-cell chronic lymphocytic leukemia
Francesca Zonta,Mario Angelo Pagano,Livio Trentin,Elena Tibaldi,Federica Frezzato,Cristina Gattazzo,Veronica Martini,Valentina Trimarco,Marco Mazzorana,Luciana Bordin,Gianpietro Semenzato,Anna Maria Brunati
MYELOID NEOPLASIA
Comparing cancer vs normal gene expression profiles identifies new disease entities and common transcriptional programs in AML patients
Nicolas Rapin,Frederik Otzen Bagger,Johan Jendholm,Helena Mora-Jensen,Anders Krogh,Alexander Kohlmann,Christian Thiede,Niels Borregaard,Lars Bullinger,Ole Winther,Kim Theilgaard-Mönch,Bo T. Porse
AZD1208, a potent and selective pan-Pim kinase inhibitor, demonstrates efficacy in preclinical models of acute myeloid leukemia
Erika K. Keeton,Kristen McEachern,Keith S. Dillman,Sangeetha Palakurthi,Yichen Cao,Michael R. Grondine,Surinder Kaur,Suping Wang,Yuching Chen,Allan Wu,Minhui Shen,Francis D. Gibbons,Michelle L. Lamb,Xiaolan Zheng,Richard M. Stone,Daniel J. DeAngelo,Leonidas C. Platanias,Les A. Dakin,Huawei Chen,Paul D. Lyne,Dennis Huszar
Mutations in the cohesin complex in acute myeloid leukemia: clinical and prognostic implications
Felicitas Thol,Robin Bollin,Marten Gehlhaar,Carolin Walter,Martin Dugas,Karl Josef Suchanek,Aylin Kirchner,Liu Huang,Anuhar Chaturvedi,Martin Wichmann,Lutz Wiehlmann,Rabia Shahswar,Frederik Damm,Gudrun Göhring,Brigitte Schlegelberger,Richard Schlenk,Konstanze Döhner,Hartmut Döhner,Jürgen Krauter,Arnold Ganser,Michael Heuser
PLATELETS AND THROMBOPOIESIS
TRANSFUSION MEDICINE
VASCULAR BIOLOGY
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Cover Image
Cover Image
![issue cover]()
Focused ion beam/scanning electron microscopy (FIB/SEM) 3D reconstruction of the pre-demarcation membrane system (pre-DMS; orange) located between the two lobes of the nucleus (gray) of an immature MK. See the article by Eckly et al on page 921.
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