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Likui Yang
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Journal Articles

Occupancy of human EPCR by protein C induces β-arrestin-2 biased PAR1 signaling by both APC and thrombin

Ram Vinod Roy, Abdolreza Ardeshirylajimi, Peyman Dinarvand, Likui Yang, Alireza R. Rezaie
Journal: Blood
Blood (2016) 128 (14): 1884–1893.
https://doi.org/10.1182/blood-2016-06-720581
Published: 2016
Includes: Supplemental data
Journal Articles

Protein C Thr315Ala variant results in gain of function but manifests as type II deficiency in diagnostic assays

Qiulan Ding, Likui Yang, Peyman Dinarvand, Xuefeng Wang, Alireza R. Rezaie
Journal: Blood
Blood (2015) 125 (15): 2428–2434.
https://doi.org/10.1182/blood-2014-12-617274
Published: 2015
Includes: Supplemental data
Journal Articles

Polyphosphate amplifies proinflammatory responses of nuclear proteins through interaction with receptor for advanced glycation end products and P2Y 1 purinergic receptor

Peyman Dinarvand, Seyed Mahdi Hassanian, Shabir H. Qureshi, Chandrashekhara Manithody, Joel C. Eissenberg, Likui Yang, Alireza R. Rezaie
Journal: Blood
Blood (2014) 123 (6): 935–945.
https://doi.org/10.1182/blood-2013-09-529602
Published: 2014
Includes: Supplemental data
Journal Articles

Factor X/Xa Elicits Protective Signaling Responses In Endothelial Cells Directly Via PAR-2 and Indirectly Via EPCR-Dependent Recruitment of PAR-1

Alireza R. Rezaie, PhD, Jong-Sup Bae, Ph.D., Likui Yang, Ph.D.
Journal: Blood
Blood (2010) 116 (21): 2115.
https://doi.org/10.1182/blood.V116.21.2115.2115
Published: 2010
Journal Articles

Characterization of Heparin Binding Site Residues on the Catalytic Domain of Factor XIa

Likui Yang, Ph.D., Mao-fu Sun, Chandrashekhara Manithody, Ph.D., David Gailani, MD, Alireza R. Rezaie, PhD
Journal: Blood
Blood (2008) 112 (11): 1018.
https://doi.org/10.1182/blood.V112.11.1018.1018
Published: 2008
Journal Articles

The ligand occupancy of endothelial protein C receptor switches the protease-activated receptor 1-dependent signaling specificity of thrombin from a permeability-enhancing to a barrier-protective response in endothelial cells

Jong-Sup Bae, Likui Yang, Chandrashekhara Manithody, Alireza R. Rezaie
Journal: Blood
Blood (2007) 110 (12): 3909–3916.
https://doi.org/10.1182/blood-2007-06-096651
Published: 2007
Journal Articles

The Ligand Occupancy of Endothelial Protein C Receptor Switches the PAR-1 Dependent Signaling Specificity of Thrombin from a Disruptive to a Protective Response in Endothelial Cells.

Alireza R. Rezaie, PhD, Jong-Sup Bae, MS, Likui Yang, Ph.D., Chandrashekhara Manithody, Ph.D.
Journal: Blood
Blood (2007) 110 (11): 1746.
https://doi.org/10.1182/blood.V110.11.1746.1746
Published: 2007
Journal Articles

Engineering a Disulfide Bond To Stabilize the Calcium Binding Loop of Activated Protein C Eliminates Its Anticoagulant but Not Protective Signaling Properties.

Jong-Sup Bae, MS, Likui Yang, Ph.D., Chandrashekhara Manithody, Ph.D., Alireza R. Rezaie, Ph.D.
Journal: Blood
Blood (2006) 108 (11): 62.
https://doi.org/10.1182/blood.V108.11.62.62
Published: 2006
Journal Articles

Heparin-activated antithrombin interacts with the autolysis loop of target coagulation proteases

Likui Yang, Chandrashekhara Manithody, Alireza R. Rezaie
Journal: Blood
Blood (2004) 104 (6): 1753–1759.
https://doi.org/10.1182/blood-2004-03-1092
Published: 2004