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Transplants for the elderly in myeloma
Bortezomib induction, reduced-intensity transplantation, and lenalidomide consolidation-maintenance for myeloma: updated results
Clofarabine doubles the response rate in older patients with acute myeloid leukemia but does not improve survival
Revised response criteria for myelofibrosis: International Working Group-Myeloproliferative Neoplasms Research and Treatment (IWG-MRT) and European LeukemiaNet (ELN) consensus report
An evolutionarily conserved program of B-cell development and activation in zebrafish
Issue Archive
Table of Contents
INSIDE BLOOD
CLINICAL TRIALS & OBSERVATIONS
Transplants for the elderly in myeloma
Clinical Trials & Observations
BLOOD WORK
PLENARY PAPER
Toward eliminating HLA class I expression to generate universal cells from allogeneic donors
Hiroki Torikai,Andreas Reik,Frank Soldner,Edus H. Warren,Carrie Yuen,Yuanyue Zhou,Denise L. Crossland,Helen Huls,Nicholas Littman,Ziying Zhang,Scott S. Tykodi,Partow Kebriaei,Dean A. Lee,Jeffrey C. Miller,Edward J. Rebar,Michael C. Holmes,Rudolf Jaenisch,Richard E. Champlin,Philip D. Gregory,Laurence J. N. Cooper
REVIEW ARTICLE
HOW I TREAT
CLINICAL TRIALS AND OBSERVATIONS
Bortezomib induction, reduced-intensity transplantation, and lenalidomide consolidation-maintenance for myeloma: updated results
Clinical Trials & Observations
Francesca Gay,Valeria Magarotto,Claudia Crippa,Norbert Pescosta,Tommasina Guglielmelli,Federica Cavallo,Sara Pezzatti,Samantha Ferrari,Anna Marina Liberati,Stefania Oliva,Francesca Patriarca,Massimo Offidani,Paola Omedé,Vittorio Montefusco,Maria Teresa Petrucci,Nicola Giuliani,Roberto Passera,Giuseppe Pietrantuono,Mario Boccadoro,Paolo Corradini,Antonio Palumbo
Clofarabine doubles the response rate in older patients with acute myeloid leukemia but does not improve survival
Clinical Trials & Observations
Alan K. Burnett,Nigel H. Russell,Ann E. Hunter,Donald Milligan,Steven Knapper,Keith Wheatley,John Yin,Mary F. McMullin,Sahra Ali,David Bowen,Robert K. Hills,on behalf of the UK National Cancer Research Institute AML Working Group
Revised response criteria for myelofibrosis: International Working Group-Myeloproliferative Neoplasms Research and Treatment (IWG-MRT) and European LeukemiaNet (ELN) consensus report
Brief Report
Ayalew Tefferi,Francisco Cervantes,Ruben Mesa,Francesco Passamonti,Srdan Verstovsek,Alessandro M. Vannucchi,Jason Gotlib,Brigitte Dupriez,Animesh Pardanani,Claire Harrison,Ronald Hoffman,Heinz Gisslinger,Nicolaus Kröger,Juergen Thiele,Tiziano Barbui,Giovanni Barosi
GENE THERAPY
IMMUNOBIOLOGY
An evolutionarily conserved program of B-cell development and activation in zebrafish
e-blood
Dawne M. Page,Valerie Wittamer,Julien Y. Bertrand,Kanako L. Lewis,David N. Pratt,Noemi Delgado,Sarah E. Schale,Caitlyn McGue,Bradley H. Jacobsen,Alyssa Doty,Yvonne Pao,Hongbo Yang,Neil C. Chi,Brad G. Magor,David Traver
LYMPHOID NEOPLASIA
HLA specificities are related to development and prognosis of diffuse large B-cell lymphoma
Miguel Alcoceba,Elena Sebastián,Luis Marín,Ana Balanzategui,M. Eugenia Sarasquete,M. Carmen Chillón,Cristina Jiménez,Noemí Puig,Rocío Corral,Emilia Pardal,Carlos Grande,José Luis Bello,Carmen Albo,Fátima de la Cruz,Carlos Panizo,Alejandro Martín,Eva González-Barca,M. Dolores Caballero,Jesús F. San Miguel,Ramón García-Sanz,Marcos González
MYELOID NEOPLASIA
SGN-CD33A: a novel CD33-targeting antibody–drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML
May S. Kung Sutherland,Roland B. Walter,Scott C. Jeffrey,Patrick J. Burke,Changpu Yu,Heather Kostner,Ivan Stone,Maureen C. Ryan,Django Sussman,Robert P. Lyon,Weiping Zeng,Kimberly H. Harrington,Kerry Klussman,Lori Westendorf,David Meyer,Irwin D. Bernstein,Peter D. Senter,Dennis R. Benjamin,Jonathan G. Drachman,Julie A. McEarchern
THROMBOSIS AND HEMOSTASIS
TRANSFUSION MEDICINE
Alloantibodies to a paternally derived RBC KEL antigen lead to hemolytic disease of the fetus/newborn in a murine model
Sean R. Stowell,Kate L. Henry,Nicole H. Smith,Krystalyn E. Hudson,Greg R. Halverson,Jaekeun C. Park,Ashley M. Bennett,Kathryn R. Girard-Pierce,C. Maridith Arthur,Silvia T. Bunting,James C. Zimring,Jeanne E. Hendrickson
TRANSPLANTATION
Rituximab prophylaxis prevents corticosteroid-requiring chronic GVHD after allogeneic peripheral blood stem cell transplantation: results of a phase 2 trial
Corey Cutler,Haesook T. Kim,Bhavjot Bindra,Stefanie Sarantopoulos,Vincent T. Ho,Yi-Bin Chen,Jacalyn Rosenblatt,Sean McDonough,Phandee Watanaboonyongcharoen,Philippe Armand,John Koreth,Brett Glotzbecker,Edwin Alyea,Bruce R. Blazar,Robert J. Soiffer,Jerome Ritz,Joseph H. Antin
VASCULAR BIOLOGY
ERRATA
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Cover Image
Cover Image
Immunofluorescence staining of developing microvasculature in a Matrigel plug in the flank of a wild-type mouse. The red-orange material is CD31; the green stain is NG2, a chondroitin 4 epitope that is a marker for vascular smooth muscle cells; and the yellow color is their colocalization. The balanced NG2/CD31 antigen ratio seen in this photomicrograph is contrasted with that seen in Matrigel plugs in PRCPgt/gt mice. Prolylcarboxypeptidase (PRCP) deficient cells have reduced endothelial cell growth and migration. PRCP deficient mice (PRCPgt/gt) have reduced angiogenesis and reduced the ability for ischemic repair. See the article by Adams et al on page 1522.
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