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Journal Articles

SGN-35C: A Novel CD30-Directed Antibody-Drug Conjugate for the Treatment of Lymphomas

Kevin J. Hamblett, Julia Cochran, Katie Snead, Steven Jin, Roma Yumul, Jessica Simmons, Ivan Stone, Ryan Lyski, Jason P. Schrum, Andrea R. Lim, Astrid Clarke
Journal: Blood
Blood (2023) 142 (Supplement 1): 1440.
https://doi.org/10.1182/blood-2023-182400
Published: 2023
Journal Articles

Denintuzumab Mafodotin Stimulates Immune Responses and Synergizes with CD20 Antibodies to Heighten Anti-Tumor Activity in Preclinical Models of Non-Hodgkin Lymphoma

Heather A. Van Epps, PhD, Ryan Heiser, PhD, Anthony Cao, PhD, Kerry Klussman, Changpu Yu, Ivan Stone, Jason Neale, PhD, Shyra J. Gardai, PhD, Che-Leung Law, PhD, Maureen C. Ryan, PhD
Journal: Blood
Blood (2016) 128 (22): 4177.
https://doi.org/10.1182/blood.V128.22.4177.4177
Published: 2016
Journal Articles

SGN-CD123A, a Pyrrolobenzodiazepine Dimer Linked Anti-CD123 Antibody Drug Conjugate, Demonstrates Effective Anti-Leukemic Activity in Multiple Preclinical Models of AML

May S.K. Sutherland, PhD, Changpu Yu, Roland B. Walter, MD PhD, Lori Westendorf, John Valliere-Douglass, PhD, Lucy Pan, PhD, Django Sussman, PhD, Martha Anderson, Weiping Zeng, Ivan Stone, Kerry Klussman, Michelle Ulrich, Mechthild Jonas, PhD, Peter Senter, PhD, Jonathan G. Drachman, MD, Dennis Benjamin, PhD
Journal: Blood
Blood (2015) 126 (23): 330.
https://doi.org/10.1182/blood.V126.23.330.330
Published: 2015
Journal Articles

SGN-CD33A: a novel CD33-targeting antibody–drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML

May S. Kung Sutherland, Roland B. Walter, Scott C. Jeffrey, Patrick J. Burke, Changpu Yu, Heather Kostner, Ivan Stone, Maureen C. Ryan, Django Sussman, Robert P. Lyon, Weiping Zeng, Kimberly H. Harrington, Kerry Klussman, Lori Westendorf, David Meyer, Irwin D. Bernstein, Peter D. Senter, Dennis R. Benjamin, Jonathan G. Drachman, Julie A. McEarchern
Journal: Blood
Blood (2013) 122 (8): 1455–1463.
https://doi.org/10.1182/blood-2013-03-491506
Published: 2013
Includes: Supplemental data
Journal Articles

SGN-CD33A: A Novel CD33-Directed Antibody-Drug Conjugate, Utilizing Pyrrolobenzodiazepine Dimers, Demonstrates Preclinical Antitumor Activity Against Multi-Drug Resistant Human AML

May S.K. Sutherland, PhD, Roland B. Walter, MD, PhD, Scott C. Jeffrey, PhD, Patrick J. Burke, PhD, Changpu Yu, MD, Kimberly H. Harrington, BS, Ivan Stone, BS, Maureen C. Ryan, PhD, Django Sussman, PhD, Weiping Zeng, MD, Dennis R. Benjamin, PhD, Irwin D. Bernstein, MD, Peter D. Senter, PhD, Jonathan G. Drachman, MD, Julie A. McEarchern, PhD
Journal: Blood
Blood (2012) 120 (21): 3589.
https://doi.org/10.1182/blood.V120.21.3589.3589
Published: 2012
Journal Articles

Potent antitumor activity of the anti-CD19 auristatin antibody drug conjugate hBU12-vcMMAE against rituximab-sensitive and -resistant lymphomas

Hans-Peter Gerber, May Kung-Sutherland, Ivan Stone, Carol Morris-Tilden, Jamie Miyamoto, Renee McCormick, Stephen C. Alley, Nicole Okeley, Brad Hayes, Francisco J. Hernandez-Ilizaliturri, Charlotte F. McDonagh, Paul J. Carter, Dennis Benjamin, Iqbal S. Grewal
Journal: Blood
Blood (2009) 113 (18): 4352–4361.
https://doi.org/10.1182/blood-2008-09-179143
Published: 2009
Includes: Supplemental data
Journal Articles

SGN-70, a Humanized Anti-CD70 Antibody, Targets CD70-Expressing Hematologic Tumors.

Julie A. McEarchern, PhD, Charlotte F. McDonagh, Ph.D., Leia M. Smith, Ph.D., Kerry Klussman, B.S., Ezogelin Oflazoglu, Ph.D., Carol Morris-Tilden, B.S., Ivan Stone, B.S., Renee McCormick, B.S., Paul Carter, Ph.D., Hanspeter Gerber, Ph.D., Iqbal S. Grewal, Ph.D., Che-Leung Law, Ph.D.
Journal: Blood
Blood (2006) 108 (11): 2492.
https://doi.org/10.1182/blood.V108.11.2492.2492
Published: 2006
Journal Articles

Engineered anti-CD70 antibody with multiple effector functions exhibits in vitro and in vivo antitumor activities

Julie A. McEarchern, Ezogelin Oflazoglu, Leigh Francisco, Charlotte F. McDonagh, Kristine A. Gordon, Ivan Stone, Kerry Klussman, Eileen Turcott, Nico van Rooijen, Paul Carter, Iqbal S. Grewal, Alan F. Wahl, Che-Leung Law
Journal: Blood
Blood (2006) 109 (3): 1185–1192.
https://doi.org/10.1182/blood-2006-07-034017
Published: 2006
Journal Articles

SGN-35, an Anti-CD30 Antibody-Drug Conjugate, Exhibits Potent Antitumor Activity for the Treatment of CD30 + Malignancies.

Kevin J. Hamblett, Jeremy Barton, Charles G. Cerveny, Jamie B. Andreyka, Kim M. Kissler, Nicole M. Okeley, Ivan Stone, May K. Sutherland, Michael M. Sun, Peter D. Senter, Alan F. Wahl, Nathan C. Ihle
Journal: Blood
Blood (2005) 106 (11): 610.
https://doi.org/10.1182/blood.V106.11.610.610
Published: 2005