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The strategy for the diagnosis of invasive pulmonary aspergillosis should depend on both the underlying condition and the leukocyte count of patients with hematologic malignancies
Patient age at diagnosis is associated with the molecular characteristics of diffuse large B-cell lymphoma
PI3Kδ inhibitor, GS-1101 (CAL-101), attenuates pathway signaling, induces apoptosis, and overcomes signals from the microenvironment in cellular models of Hodgkin lymphoma
Responses to second-line tyrosine kinase inhibitors are durable: an intention-to-treat analysis in chronic myeloid leukemia patients
In vivo imaging visualizes discoid platelet aggregations without endothelium disruption and implicates contribution of inflammatory cytokine and integrin signaling
Issue Archive
February 23 2012
In this Issue
Table of Contents
Inside Blood
Blood Work
Perspectives
Review Article
How I treat
Clinical Trials and Observations
The strategy for the diagnosis of invasive pulmonary aspergillosis should depend on both the underlying condition and the leukocyte count of patients with hematologic malignancies
CME
Anne Bergeron,Raphaël Porcher,Annie Sulahian,Cédric de Bazelaire,Karine Chagnon,Emmanuel Raffoux,Anne Vekhoff,Muriel Cornet,Françoise Isnard,Benoit Brethon,Claire Lacroix,Jean Louis Poirot,Claire Bouges,Francis Derouin,Abdellatif Tazi,Patricia Ribaud
Hematopoiesis and Stem Cells
Immunobiology
Lymphoid Neoplasia
Gene expression profiles predictive of outcome and age in infant acute lymphoblastic leukemia: a Children's Oncology Group study
Huining Kang,Carla S. Wilson,Richard C. Harvey,I.-Ming Chen,Maurice H. Murphy,Susan R. Atlas,Edward J. Bedrick,Meenakshi Devidas,Andrew J. Carroll,Blaine W. Robinson,Ronald W. Stam,Maria G. Valsecchi,Rob Pieters,Nyla A. Heerema,Joanne M. Hilden,Carolyn A. Felix,Gregory H. Reaman,Bruce Camitta,Naomi Winick,William L. Carroll,ZoAnn E. Dreyer,Stephen P. Hunger,Cheryl L. Willman
Patient age at diagnosis is associated with the molecular characteristics of diffuse large B-cell lymphoma
Clinical Trials & Observations
Wolfram Klapper,Markus Kreuz,Christian W. Kohler,Birgit Burkhardt,Monika Szczepanowski,Itziar Salaverria,Michael Hummel,Markus Loeffler,Shoji Pellissery,Wilhelm Woessmann,Carsten Schwänen,Lorenz Trümper,Swen Wessendorf,Rainer Spang,Dirk Hasenclever,Reiner Siebert,for the Molecular Mechanisms in Malignant Lymphomas Network Project of the Deutsche Krebshilfe
PI3Kδ inhibitor, GS-1101 (CAL-101), attenuates pathway signaling, induces apoptosis, and overcomes signals from the microenvironment in cellular models of Hodgkin lymphoma
Brief Report
Sarah A. Meadows,Francisco Vega,Adam Kashishian,Dave Johnson,Volker Diehl,Langdon L. Miller,Anas Younes,Brian J. Lannutti
Myeloid Neoplasia
Responses to second-line tyrosine kinase inhibitors are durable: an intention-to-treat analysis in chronic myeloid leukemia patients
Clinical Trials & Observations
Dragana Milojkovic,Jane F. Apperley,Gareth Gerrard,Amr R. Ibrahim,Richard Szydlo,Marco Bua,Alistair Reid,Katayoun Rezvani,Letizia Foroni,John Goldman,David Marin
Red Cells, Iron, and Erythropoiesis
Hydroxyurea therapy of a murine model of sickle cell anemia inhibits the progression of pneumococcal disease by down-modulating E-selectin
Jeffrey D. Lebensburger,Thad Howard,Yunming Hu,Tamara I. Pestina,Geli Gao,Melissa Johnson,Stanislav S. Zakharenko,Russell E. Ware,Elaine I. Tuomanen,Derek A. Persons,Jason W. Rosch
Thrombosis and Hemostasis
A newly identified complex of spinophilin and the tyrosine phosphatase, SHP-1, modulates platelet activation by regulating G protein–dependent signaling
Peisong Ma,Aleksandra Cierniewska,Rachel Signarvic,Marcin Cieslak,Hong Kong,Andrew J. Sinnamon,Richard R. Neubig,Debra K. Newman,Timothy J. Stalker,Lawrence F. Brass
In vivo imaging visualizes discoid platelet aggregations without endothelium disruption and implicates contribution of inflammatory cytokine and integrin signaling
e-blood
Satoshi Nishimura,Ichiro Manabe,Mika Nagasaki,Shigeru Kakuta,Yoichiro Iwakura,Naoya Takayama,Jun Ooehara,Makoto Otsu,Akihide Kamiya,Brian G. Petrich,Tetsumei Urano,Takafumi Kadono,Shinichi Sato,Atsu Aiba,Hiroshi Yamashita,Seiryo Sugiura,Takashi Kadowaki,Hiromitsu Nakauchi,Koji Eto,Ryozo Nagai
Transplantation
Vascular Biology
Other Departments
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Cover Image
Cover Image
![issue cover]()
The cover image shows a 3-dimensional fibrin gel bead assay in which Shc-deficient endothelial cells are shown abnormally extending numerous filopodia from the beads into the matrix, instead of forming capillary-like multicellular sprouts as seen with wildtype endothelial cells. F-actin is stained green (phalloidin) and nuclei are stained blue (DRAQ5). See the article by Sweet et al on page 1946.
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