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ALK-negative anaplastic large cell lymphoma: features and outcomes of 235 patients from the International T-Cell Project
Denosumab compared with zoledronic acid on PFS in multiple myeloma: exploratory results of an international phase 3 study
PML-controlled responses in severe congenital neutropenia with ELANE-misfolding mutations
Genomic landscape of cutaneous follicular lymphomas reveals 2 subgroups with clinically predictive molecular features
Efficacy and safety of copanlisib in patients with relapsed or refractory marginal zone lymphoma
Measurable residual disease in elderly acute myeloid leukemia: results from the PETHEMA-FLUGAZA phase 3 clinical trial
Allogeneic stem cell transplantation with omidubicel in sickle cell disease
COVID-19 and hematopoietic stem cell transplantation and immune effector cell therapy: a US cancer center experience
Dynamic angiopoietin-2 assessment predicts survival and chronic course in hospitalized patients with COVID-19
Impact of treatment delay in acute myeloid leukemia revisited
Issue Archive
February 9 2021
In this Issue
Table of Contents
CLINICAL GUIDELINES
American Society of Hematology 2021 guidelines on the use of anticoagulation for thromboprophylaxis in patients with COVID-19
Adam Cuker,Eric K. Tseng,Robby Nieuwlaat,Pantep Angchaisuksiri,Clifton Blair,Kathryn Dane,Jennifer Davila,Maria T. DeSancho,David Diuguid,Daniel O. Griffin,Susan R. Kahn,Frederikus A. Klok,Alfred Ian Lee,Ignacio Neumann,Ashok Pai,Menaka Pai,Marc Righini,Kristen M. Sanfilippo,Deborah Siegal,Mike Skara,Kamshad Touri,Elie A. Akl,Imad Bou Akl,Mary Boulos,Romina Brignardello-Petersen,Rana Charide,Matthew Chan,Karin Dearness,Andrea J. Darzi,Philipp Kolb,Luis E. Colunga-Lozano,Razan Mansour,Gian Paolo Morgano,Rami Z. Morsi,Atefeh Noori,Thomas Piggott,Yuan Qiu,Yetiani Roldan,Finn Schünemann,Adrienne Stevens,Karla Solo,Matthew Ventresca,Wojtek Wiercioch,Reem A. Mustafa,Holger J. Schünemann
EXCEPTIONAL CASE REPORT
STIMULUS REPORTS
Dissemination of extreme levels of extracellular vesicles: tissue factor activity in patients with severe COVID-19
Christophe Guervilly,Amandine Bonifay,Stephane Burtey,Florence Sabatier,Raphaël Cauchois,Evelyne Abdili,Laurent Arnaud,Guillaume Lano,Léa Pietri,Thomas Robert,Mélanie Velier,Laurent Papazian,Jacques Albanese,Gilles Kaplanski,Françoise Dignat-George,Romaric Lacroix
REVIEW ARTICLE
CLINICAL TRIALS AND OBSERVATIONS
ALK-negative anaplastic large cell lymphoma: features and outcomes of 235 patients from the International T-Cell Project
Clinical Trials & Observations
Andrei Shustov,on behalf of the T-cell Lymphoma Project,Maria Elena Cabrera,on behalf of the T-cell Lymphoma Project,Monica Civallero,on behalf of the T-cell Lymphoma Project,Monica Bellei,on behalf of the T-cell Lymphoma Project,Young Hyeh Ko,on behalf of the T-cell Lymphoma Project,Martina Manni,on behalf of the T-cell Lymphoma Project,Tetiana Skrypets,on behalf of the T-cell Lymphoma Project,Steven M. Horwitz,on behalf of the T-cell Lymphoma Project,Carmino Antonio De Souza,on behalf of the T-cell Lymphoma Project,John A. Radford,on behalf of the T-cell Lymphoma Project,Sabela Bobillo,on behalf of the T-cell Lymphoma Project,Maria Virginia Prates,on behalf of the T-cell Lymphoma Project,Andrés J. M. Ferreri,on behalf of the T-cell Lymphoma Project,Carlos Chiattone,on behalf of the T-cell Lymphoma Project,Michele Spina,on behalf of the T-cell Lymphoma Project,Julie M. Vose,on behalf of the T-cell Lymphoma Project,Annalisa Chiappella,on behalf of the T-cell Lymphoma Project,Daniele Laszlo,on behalf of the T-cell Lymphoma Project,Dario Marino,on behalf of the T-cell Lymphoma Project,Caterina Stelitano,on behalf of the T-cell Lymphoma Project,Massimo Federico,on behalf of the T-cell Lymphoma Project
Denosumab compared with zoledronic acid on PFS in multiple myeloma: exploratory results of an international phase 3 study
Clinical Trials & Observations
Evangelos Terpos,Noopur Raje,Peter Croucher,Ramon Garcia-Sanz,Xavier Leleu,Waltraud Pasteiner,Yang Wang,Anthony Glennane,Jude Canon,Charlotte Pawlyn
HEMATOPOIESIS AND STEM CELLS
PML-controlled responses in severe congenital neutropenia with ELANE-misfolding mutations
Clinical Trials & Observations
Patricia A. Olofsen,Dennis A. Bosch,Onno Roovers,Paulina M. H. van Strien,Hans W. J. de Looper,Remco M. Hoogenboezem,Sander Barnhoorn,Pier G. Mastroberardino,Mehrnaz Ghazvini,Vincent H. J. van der Velden,Eric M. J. Bindels,Emma M. de Pater,Ivo P. Touw
JMJD6 promotes self-renewal and regenerative capacity of hematopoietic stem cells
Hannah Lawson,Catarina Sepulveda,Louie N. van de Lagemaat,Jozef Durko,Melania Barile,Andrea Tavosanis,Elise Georges,Alena Shmakova,Penny Timms,Roderick N. Carter,Lewis Allen,Joana Campos,Milica Vukovic,Amelie V. Guitart,Peter Giles,Marie O’Shea,Douglas Vernimmen,Nicholas M. Morton,Neil P. Rodrigues,Berthold Göttgens,Christopher J. Schofield,Andreas Lengeling,Dónal O’Carroll,Kamil R. Kranc
LYMPHOID NEOPLASIA
Genomic landscape of cutaneous follicular lymphomas reveals 2 subgroups with clinically predictive molecular features
Clinical Trials & Observations
Xiaolong Alan Zhou,Jingyi Yang,Kimberly G. Ringbloom,Maria Estela Martinez-Escala,Kristen E. Stevenson,Alexander T. Wenzel,Damiano Fantini,Haley K. Martin,Andrea P. Moy,Elizabeth A. Morgan,Shannon Harkins,Christian N. Paxton,Bo Hong,Erica F. Andersen,Joan Guitart,David M. Weinstock,Lorenzo Cerroni,Jaehyuk Choi,Abner Louissaint, Jr
Efficacy and safety of copanlisib in patients with relapsed or refractory marginal zone lymphoma
Clinical Trials & Observations
Panayiotis Panayiotidis,George A. Follows,Luigina Mollica,Arnon Nagler,Muhit Özcan,Armando Santoro,Don Stevens,David Trevarthen,Florian Hiemeyer,Jose Garcia-Vargas,Barrett H. Childs,Pier Luigi Zinzani,Martin Dreyling
MYELOID NEOPLASIA
Restoring RUNX1 deficiency in RUNX1 familial platelet disorder by inhibiting its degradation
Michelle C. Krutein,Matthew R. Hart,Donovan J. Anderson,Jasmin Jeffery,Andriana G. Kotini,Jin Dai,Sylvia Chien,Michaela DelPriore,Sara Borst,Jean Ann Maguire,Deborah L. French,Paul Gadue,Eirini P. Papapetrou,Siobán B. Keel,Pamela S. Becker,Marshall S. Horwitz
Measurable residual disease in elderly acute myeloid leukemia: results from the PETHEMA-FLUGAZA phase 3 clinical trial
Clinical Trials & Observations
Catia Simoes,on behalf of the Programa para el Estudio de la Terapéutica en Hemopatías Malignas (PETHEMA) Cooperative Study Group,Bruno Paiva,on behalf of the Programa para el Estudio de la Terapéutica en Hemopatías Malignas (PETHEMA) Cooperative Study Group,David Martínez-Cuadrón,on behalf of the Programa para el Estudio de la Terapéutica en Hemopatías Malignas (PETHEMA) Cooperative Study Group,Juan-Miguel Bergua,on behalf of the Programa para el Estudio de la Terapéutica en Hemopatías Malignas (PETHEMA) Cooperative Study Group,Susana Vives,on behalf of the Programa para el Estudio de la Terapéutica en Hemopatías Malignas (PETHEMA) Cooperative Study Group,Lorenzo Algarra,on behalf of the Programa para el Estudio de la Terapéutica en Hemopatías Malignas (PETHEMA) Cooperative Study Group,Mar Tormo,on behalf of the Programa para el Estudio de la Terapéutica en Hemopatías Malignas (PETHEMA) Cooperative Study Group,Pilar Martinez,on behalf of the Programa para el Estudio de la Terapéutica en Hemopatías Malignas (PETHEMA) Cooperative Study Group,Josefina Serrano,on behalf of the Programa para el Estudio de la Terapéutica en Hemopatías Malignas (PETHEMA) Cooperative Study Group,Pilar Herrera,on behalf of the Programa para el Estudio de la Terapéutica en Hemopatías Malignas (PETHEMA) Cooperative Study Group,Fernando Ramos,on behalf of the Programa para el Estudio de la Terapéutica en Hemopatías Malignas (PETHEMA) Cooperative Study Group,Olga Salamero,on behalf of the Programa para el Estudio de la Terapéutica en Hemopatías Malignas (PETHEMA) Cooperative Study Group,Esperanza Lavilla,on behalf of the Programa para el Estudio de la Terapéutica en Hemopatías Malignas (PETHEMA) Cooperative Study Group,Cristina Gil,on behalf of the Programa para el Estudio de la Terapéutica en Hemopatías Malignas (PETHEMA) Cooperative Study Group,Jose-Luis Lopez,on behalf of the Programa para el Estudio de la Terapéutica en Hemopatías Malignas (PETHEMA) Cooperative Study Group,Maria-Belen Vidriales,on behalf of the Programa para el Estudio de la Terapéutica en Hemopatías Malignas (PETHEMA) Cooperative Study Group,Jorge Labrador,on behalf of the Programa para el Estudio de la Terapéutica en Hemopatías Malignas (PETHEMA) Cooperative Study Group,Jose-Francisco Falantes,on behalf of the Programa para el Estudio de la Terapéutica en Hemopatías Malignas (PETHEMA) Cooperative Study Group,María-José Sayas,on behalf of the Programa para el Estudio de la Terapéutica en Hemopatías Malignas (PETHEMA) Cooperative Study Group,Rosa Ayala,on behalf of the Programa para el Estudio de la Terapéutica en Hemopatías Malignas (PETHEMA) Cooperative Study Group,Joaquin Martinez-Lopez,on behalf of the Programa para el Estudio de la Terapéutica en Hemopatías Malignas (PETHEMA) Cooperative Study Group,Sara Villar,on behalf of the Programa para el Estudio de la Terapéutica en Hemopatías Malignas (PETHEMA) Cooperative Study Group,Maria-Jose Calasanz,on behalf of the Programa para el Estudio de la Terapéutica en Hemopatías Malignas (PETHEMA) Cooperative Study Group,Felipe Prosper,on behalf of the Programa para el Estudio de la Terapéutica en Hemopatías Malignas (PETHEMA) Cooperative Study Group,Jesús F. San-Miguel,on behalf of the Programa para el Estudio de la Terapéutica en Hemopatías Malignas (PETHEMA) Cooperative Study Group,Miguel Ángel Sanz,on behalf of the Programa para el Estudio de la Terapéutica en Hemopatías Malignas (PETHEMA) Cooperative Study Group,Pau Montesinos,on behalf of the Programa para el Estudio de la Terapéutica en Hemopatías Malignas (PETHEMA) Cooperative Study Group
Genomic characterization of relapsed acute myeloid leukemia reveals novel putative therapeutic targets
Svea Stratmann,Sara A. Yones,Markus Mayrhofer,Nina Norgren,Aron Skaftason,Jitong Sun,Karolina Smolinska,Jan Komorowski,Morten Krogh Herlin,Christer Sundström,Anna Eriksson,Martin Höglund,Josefine Palle,Jonas Abrahamsson,Kirsi Jahnukainen,Monica Cheng Munthe-Kaas,Bernward Zeller,Katja Pokrovskaja Tamm,Lucia Cavelier,Linda Holmfeldt
PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS
THROMBOSIS AND HEMOSTASIS
Molecular coevolution of coagulation factor VIII and von Willebrand factor
Philip M. Zakas,Christopher W. Coyle,Anja Brehm,Marion Bayer,Barbara Solecka-Witulska,Caelan E. Radford,Christine Brown,Kate Nesbitt,Courtney Dwyer,Christoph Kannicht,H. Trent Spencer,Eric A. Gaucher,Christopher B. Doering,David Lillicrap
TRANSFUSION MEDICINE
TRANSPLANTATION
Allogeneic stem cell transplantation with omidubicel in sickle cell disease
Clinical Trials & Observations
COVID-19 and hematopoietic stem cell transplantation and immune effector cell therapy: a US cancer center experience
Clinical Trials & Observations
Katie Maurer,Anna Saucier,Haesook T. Kim,Utkarsh Acharya,Clifton C. Mo,Julie Porter,Cindy Albert,Corey Cutler,Joseph H. Antin,John Koreth,Mahasweta Gooptu,Rizwan Romee,Catherine J. Wu,Robert J. Soiffer,Sarah Nikiforow,Caron Jacobson,Vincent T. Ho
VASCULAR BIOLOGY
Dynamic angiopoietin-2 assessment predicts survival and chronic course in hospitalized patients with COVID-19
Clinical Trials & Observations
Erica Villa,Rosina Critelli,Simone Lasagni,Alessandra Melegari,Angela Curatolo,Ciro Celsa,Dante Romagnoli,Gabriele Melegari,Alessandra Pivetti,Lorenza Di Marco,Federico Casari,Dimitriy Arioli,Fabrizio Turrini,Valentina Zuccaro,Irene Cassaniti,Mattia Riefolo,Elena de Santis,Veronica Bernabucci,Marcello Bianchini,Barbara Lei,Nicola De Maria,Lucia Carulli,Filippo Schepis,Chiara Gozzi,Silvio Malaguti,Mariagrazia Del Buono,Lucio Brugioni,Pietro Torricelli,Tommaso Trenti,Giovanni Pinelli,Elisabetta Bertellini,Raffaele Bruno,Calogero Cammà,Antonia d’Errico
COMMENTARIES
Impact of treatment delay in acute myeloid leukemia revisited
Clinical Trials & Observations
Gunnar Juliusson,for the Swedish AML Registry,Oskar Hagberg,for the Swedish AML Registry,Vladimir Lj Lazarevic,for the Swedish AML Registry,Sören Lehmann,for the Swedish AML Registry,Martin Höglund,for the Swedish AML Registry
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Cover Image
Cover Image
COVER FIGURE
G-protein–coupled receptor 56 (Gpr56) expression in the aorta of a wild-type 10.5-day-old embryonic mouse, as detected by in situ hybridization. See the article by Maglitto et al. - PDF Icon PDF LinkFront Matter
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