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Christopher B. Doering
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Journal Articles

SAXS analysis of the intrinsic tenase complex bound to a lipid nanodisc highlights intermolecular contacts between factors VIIIa/IXa

Kenneth C. Childers, Shaun C. Peters, Pete Lollar, Harold Trent Spencer, Christopher B. Doering, Paul C. Spiegel, Jr
Journal: Blood Advances
Blood Adv (2022) 6 (11): 3240–3254.
https://doi.org/10.1182/bloodadvances.2021005874
Published: 2022
Includes: Supplemental data
Journal Articles

Pharmacokinetic analysis identifies a factor VIII immunogenicity threshold after AAV gene therapy in hemophilia A mice

Taran S. Lundgren, Gabriela Denning, Sean R. Stowell, H. Trent Spencer, Christopher B. Doering
Journal: Blood Advances
Blood Adv (2022) 6 (8): 2628–2645.
https://doi.org/10.1182/bloodadvances.2021006359
Published: 2022
Includes: Supplemental data
Journal Articles

Identification of coagulation factor IX variants with enhanced activity through ancestral sequence reconstruction

Kristopher A. Knight, Christopher W. Coyle, Caelan E. Radford, Ernest T. Parker, Andrew Fedanov, Jordan M. Shields, Fania Szlam, Anatolii Purchel, Michelle Chen, Gabriela Denning, Roman M. Sniecinski, Pete Lollar, H. Trent Spencer, Eric A. Gaucher, Christopher B. Doering
Journal: Blood Advances
Blood Adv (2021) 5 (17): 3333–3343.
https://doi.org/10.1182/bloodadvances.2021004742
Published: 2021
Includes: Supplemental data
Journal Articles

Molecular coevolution of coagulation factor VIII and von Willebrand factor

Philip M. Zakas, Christopher W. Coyle, Anja Brehm, Marion Bayer, Barbara Solecka-Witulska, Caelan E. Radford, Christine Brown, Kate Nesbitt, Courtney Dwyer, Christoph Kannicht, H. Trent Spencer, Eric A. Gaucher, Christopher B. Doering, David Lillicrap
Journal: Blood Advances
Blood Adv (2021) 5 (3): 812–822.
https://doi.org/10.1182/bloodadvances.2020002971
Published: 2021
Includes: Supplemental data
Journal Articles

High-level protein production in erythroid cells derived from in vivo transduced hematopoietic stem cells

Hongjie Wang, Zhinan Liu, Chang Li, Sucheol Gil, Thalia Papayannopoulou, Christopher B. Doering, André Lieber
Journal: Blood Advances
Blood Adv (2019) 3 (19): 2883–2894.
https://doi.org/10.1182/bloodadvances.2019000706
Published: 2019
Includes: Supplemental data