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Journal Articles

The Mitochondrial Protease, Neurolysin (NLN), Regulates Respiratory Chain Complex and Supercomplex Formation and Is Necessary for AML Viability

Blood (2019) 134 (Supplement_1): 729.

https://doi.org/10.1182/blood-2019-122784

Published: 2019

Journal Articles

Proteomic Analysis of Mitochondrial Membrane Protein FAM210B in Erythroid Cells

Chie Suzuki, Tohru Fujiwara, MD PhD, Hiroki Shima, Koya Ono, MD, Kei Saito, Noriko Fukuhara, MD PhD, Yasushi Onishi, MD PhD, Hisayuki Yokoyama, MD PhD, Shinichi Fujimaki, Yukio Nakamura, MD PhD, Hideo Harigae, MD PhD

Blood (2019) 134 (Supplement_1): 3523.

https://doi.org/10.1182/blood-2019-122618

Published: 2019

Journal Articles

The Role of SOD2 in Maintaining Endothelial Cell Function in SCD

Atinuke Dosunmu-Ogunbi, Yingze Zhang, PhD, Seyed Mehdi Nouraie, PhD MD, Adam Straub, PhD

Blood (2019) 134 (Supplement_1): 3563.

https://doi.org/10.1182/blood-2019-131238

Published: 2019

Journal Articles

Loss of ZBTB7A Enhances Glycolysis and Beta Oxidation in Myeloid Leukemia

Enric Redondo Monte, MSc, BSc, Anja Wilding, MSc, Georg Leubolt, MSc, Paul Kerbs, MSc, Johannes Bagnoli, Wolfgang Hiddemann, MD PhD, Wolfgang Enard, PhD, Sebastian Theurich, MD, Philipp A. Greif, MD PD

Blood (2019) 134 (Supplement_1): 1453.

https://doi.org/10.1182/blood-2019-128378

Published: 2019

Journal Articles

Mitochondrial Dysfunction in Normal and Malignant Hematopoiesis

Aaron Schimmer, MD PhD

Blood (2018) 132 (Supplement 1): SCI-11.

https://doi.org/10.1182/blood-2018-99-109470

Published: 2018

Journal Articles

The Mitochondrial Protease, Neurolysin (NLN), Regulates Respiratory Chain Supercomplex Formation and Represents a New Therapeutic Target for AML

Sara Mirali, Botham Aaron, Veronique Voisin, PhD, Yihua Qiu, Fieke W Hoff, BSc, Rose Hurren, BSc, Marcela Gronda, MSc, Yulia Jitkova, PhD, G. Wei Xu, Neil MacLean, Xiaoming Wang, Terzah M. Horton, MD PhD, Steven M. Kornblau, MD, Steven M Chan, MD PhD, Gary D Bader, Aaron Schimmer, MD PhD

Blood (2018) 132 (Supplement 1): 1335.

https://doi.org/10.1182/blood-2018-99-110869

Published: 2018

Journal Articles

The Mitochondrial Carrier Homolog 2 (MTCH2) Regulates the Differentiation of AML Cells By Influencing the Localization of Pyruvate Dehydrogenase Complex and H3 and H4 Histone Acetylation

Dilshad H. Khan, PhD, Michael Mullokandov, Yan Wu, Marcela Gronda, Rose Hurren, Xiaoming Wang, Neil MacLean, Rob C. Laister, PhD, Atan Gross, Aaron D. Schimmer, MD PhD

Blood (2016) 128 (22): 1562.

https://doi.org/10.1182/blood.V128.22.1562.1562

Published: 2016

Journal Articles

Metabolic Profiling of Adult Acute Myeloid Leukemia (AML)

Blood (2016) 128 (22): 1684.

https://doi.org/10.1182/blood.V128.22.1684.1684

Published: 2016

Journal Articles

A recurring mutation in the respiratory complex 1 protein NDUFB11 is responsible for a novel form of X-linked sideroblastic anemia

Daniel A. Lichtenstein, Andrew W. Crispin, Anoop K. Sendamarai, Dean R. Campagna, Klaus Schmitz-Abe, Cristovao M. Sousa, Martin D. Kafina, Paul J. Schmidt, Charlotte M. Niemeyer, John Porter, Alison May, Mrinal M. Patnaik, Matthew M. Heeney, Alec Kimmelman, Sylvia S. Bottomley, Barry H. Paw, Kyriacos Markianos, Mark D. Fleming

Blood (2016) 128 (15): 1913–1917.

https://doi.org/10.1182/blood-2016-05-719062

Published: 2016

Includes: Supplemental data

Journal Articles

AML cells have low spare reserve capacity in their respiratory chain that renders them susceptible to oxidative metabolic stress

Blood (2015) 125 (13): 2120–2130.

https://doi.org/10.1182/blood-2014-08-594408

Published: 2015

Includes: Supplemental data

Journal Articles

AML Cells Have Altered Mitochondrial Biogenesis and Low Spare Reserve Capacity in Their Respiratory Chain That Renders Them Susceptible to Oxidative Metabolic Stress.

Shrivani Sriskanthadevan, PhD, Timothy E Chung, Marko Skrtic, PhD, Bozhena Jhas, BSc, Rose Hurren, BSc, Marcela Gronda, MSc, Xiao Ming Wang, Yulia Jitkova, PhD, Mahadeo A. Sukhai, PhD, Feng-Hsu Lin, PhD, Neil Maclean, BSc, Rob C. Laister, PhD, Peter Mullen, PhD, Stephanie Xie, Linda Penn, PhD, Ian M. Rogers, PhD, John E. Dick, PhD $, Mark D. Minden, MD, PhD, Aaron D Schimmer, MD, PhD

Blood (2012) 120 (21): 2581.

https://doi.org/10.1182/blood.V120.21.2581.2581

Published: 2012

Journal Articles

Chronic Inhibition of Mitochondrial Translation Alters Metabolism and Stemness in AML

Jhas Bozhena, BSc, Shrivani Sriskanthadevan, PhD, Marko Skrtic, PhD, Mahadeo A. Sukhai, PhD, Veronique Voisin, PhD, Yulia Jitkova, PhD, Marcela Gronda, MSc, Rose Hurren, BSc, Xiaoming Wang, Rob C. Laister, PhD, Gary D. Bader, Ph.D., Mark D. Minden, MD, PhD, Aaron D. Schimmer, MD

Blood (2012) 120 (21): 1364.

https://doi.org/10.1182/blood.V120.21.1364.1364

Published: 2012

Journal Articles

Targeting Rac2 - Mitochondrial Respiratory Chain Complex III Signaling to Prevent Genomic Instability in Leukemia Stem and Progenitor Cells

Blood (2011) 118 (21): 2736.

https://doi.org/10.1182/blood.V118.21.2736.2736

Published: 2011

Journal Articles

AML Cells Have Increased Mitochondrial Mass but Less Reserve in Their Respiratory Chain Complexes Leading to Heightened Sensitivity to Inhibition of Mitochondrial Protein Translation,

Shrivani Sriskanthadevan, PhD, Skrtic Marko, BSc, Bozhena Livak, BSc, Yulia Jitkova, PhD, Rose Hurren, BSc, Marcela Gronda, MSc, Rob Laister, PhD, Peter Mullen, PhD, Linda Penn, PhD, Mark D. Minden, MD, PhD, Aaron D Schimmer, MD, PhD

Blood (2011) 118 (21): 3585.

https://doi.org/10.1182/blood.V118.21.3585.3585

Published: 2011

Journal Articles

Mitochondrial Respiratory Chain Complex III Causes Genomic Instability In CML-CP.

Piotr Kopinski, Margaret Nieborowska-Skorska, MD, PhD, Grazyna Hoser, PhD, Danielle Ngaba, Regina Ray, Mateusz Koptyra, PhD, Elisabeth Bolton, Ilona Seferynska, MD, PhD, Tomasz Stoklosa, MD, PhD, Artur Slupianek, PhD, Mamatha R. Reddy, Martin Sattler, PhD, Tomasz Skorski, MD, PhD

Blood (2010) 116 (21): 1211.

https://doi.org/10.1182/blood.V116.21.1211.1211

Published: 2010

Journal Articles

ROS-Induced DNA Damage Causing Genomic Instability in CML Stem and/or Progenitor Cells and in Quiescent and/or Proliferating Cells: Role of Mitochondrial Respiratory Chain Complex III.

Margaret Nieborowska-Skorska, Ph.D., Mateusz Koptyra, PhD, Elisabeth Bolton, Regina Ray, Danielle Ngaba, Grazyna Hoser, PhD, Tomasz Stoklosa, M.D., Ph.D., Artur Slupianek, PhD, Piotr Kopinski, Tomasz Skorski, MD, PhD

Blood (2009) 114 (22): 3268.

https://doi.org/10.1182/blood.V114.22.3268.3268

Published: 2009

Journal Articles

Somatic Expansion of the Frataxin Gene GAA Repeats in MDS Patients.

Drorit Merkel, MD, H. Joachim Deeg, Amos Simon, B.A., Ninette Amariglio, PhD, Arnon Nagler, M.D., Gideon Rechavi, MD, PhD

Blood (2008) 112 (11): 1642.

https://doi.org/10.1182/blood.V112.11.1642.1642

Published: 2008

Journal Articles

Impaired Activity of Mitochondrial Respiratory Chain Enzyme Complexes and Mitochondrial Genomic Aberrations in Leukemia Cells from Patients with Acute Myeloid Leukemia.

Myung-Geun Shin, MD, Hyeoung Joon Kim, MD, Hye-Ran Kim, MS, Il-Kwon Lee, PhD, Duck Cho, MD, Seung-Jung Kee, MD, Hoon Kook, MD, Tai-Ju Hwang, MD, Jong-Hee Shin, MD, Soon-Pal Suh, MD, Dong-Wook Ryang, MD

Blood (2006) 108 (11): 1918.

https://doi.org/10.1182/blood.V108.11.1918.1918

Published: 2006

Journal Articles

Study of Uncoupling Protein 2 (UCP2) Function during Erythroid Differentiation and Maturation.

Alvaro A. Elorza, PhD, Sarah E. Haigh, PhD, Hanna K. Mikkola, MD, Orian S. Shirihai, MD, PhD

Blood (2005) 106 (11): 3535.

https://doi.org/10.1182/blood.V106.11.3535.3535

Published: 2005

Journal Articles

Ineffective hematopoiesis linked with a mitochondrial tRNA mutation (G3242A) in a patient with myelodysplastic syndrome

Norbert Gattermann, Michael Wulfert, Bärbel Junge, Ulrich Germing, Rainer Haas, Götz Hofhaus

Blood (2004) 103 (4): 1499–1502.

https://doi.org/10.1182/blood-2003-07-2446

Published: 2004

NARROW

The Mitochondrial Protease, Neurolysin (NLN), Regulates Respiratory Chain Complex and Supercomplex Formation and Is Necessary for AML Viability

Proteomic Analysis of Mitochondrial Membrane Protein FAM210B in Erythroid Cells

The Role of SOD2 in Maintaining Endothelial Cell Function in SCD

Loss of ZBTB7A Enhances Glycolysis and Beta Oxidation in Myeloid Leukemia

Mitochondrial Dysfunction in Normal and Malignant Hematopoiesis

The Mitochondrial Protease, Neurolysin (NLN), Regulates Respiratory Chain Supercomplex Formation and Represents a New Therapeutic Target for AML

The Mitochondrial Carrier Homolog 2 (MTCH2) Regulates the Differentiation of AML Cells By Influencing the Localization of Pyruvate Dehydrogenase Complex and H3 and H4 Histone Acetylation

Metabolic Profiling of Adult Acute Myeloid Leukemia (AML)

A recurring mutation in the respiratory complex 1 protein NDUFB11 is responsible for a novel form of X-linked sideroblastic anemia

AML cells have low spare reserve capacity in their respiratory chain that renders them susceptible to oxidative metabolic stress

AML Cells Have Altered Mitochondrial Biogenesis and Low Spare Reserve Capacity in Their Respiratory Chain That Renders Them Susceptible to Oxidative Metabolic Stress.

Chronic Inhibition of Mitochondrial Translation Alters Metabolism and Stemness in AML

Targeting Rac2 - Mitochondrial Respiratory Chain Complex III Signaling to Prevent Genomic Instability in Leukemia Stem and Progenitor Cells

AML Cells Have Increased Mitochondrial Mass but Less Reserve in Their Respiratory Chain Complexes Leading to Heightened Sensitivity to Inhibition of Mitochondrial Protein Translation,

Mitochondrial Respiratory Chain Complex III Causes Genomic Instability In CML-CP.

ROS-Induced DNA Damage Causing Genomic Instability in CML Stem and/or Progenitor Cells and in Quiescent and/or Proliferating Cells: Role of Mitochondrial Respiratory Chain Complex III.

Somatic Expansion of the Frataxin Gene GAA Repeats in MDS Patients.

Impaired Activity of Mitochondrial Respiratory Chain Enzyme Complexes and Mitochondrial Genomic Aberrations in Leukemia Cells from Patients with Acute Myeloid Leukemia.

Study of Uncoupling Protein 2 (UCP2) Function during Erythroid Differentiation and Maturation.

Ineffective hematopoiesis linked with a mitochondrial tRNA mutation (G3242A) in a patient with myelodysplastic syndrome

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American Society of Hematology

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ASH Publications

American Society of Hematology

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