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Journal Articles

AML cells have low spare reserve capacity in their respiratory chain that renders them susceptible to oxidative metabolic stress

Shrivani Sriskanthadevan, Danny V. Jeyaraju, Timothy E. Chung, Swayam Prabha, Wei Xu, Marko Skrtic, Bozhena Jhas, Rose Hurren, Marcela Gronda, Xiaoming Wang, Yulia Jitkova, Mahadeo A. Sukhai, Feng-Hsu Lin, Neil Maclean, Rob Laister, Carolyn A. Goard, Peter J. Mullen, Stephanie Xie, Linda Z. Penn, Ian M. Rogers, John E. Dick, Mark D. Minden, Aaron D. Schimmer
Journal: Blood
Blood (2015) 125 (13): 2120–2130.
https://doi.org/10.1182/blood-2014-08-594408
Published: 2015
Includes: Supplemental data
Journal Articles

Ibrutinib Sensitizes AML Cells to ROS Inducers Via a BTK-Independent Mechanism

Lianne E Rotin, BHSc, Marcela Gronda, MSc, Neil Maclean, BSc, Feng-Hsu Lin, PhD, Jeff Wrana, PhD, Alessandro Datti, PhD, Dwayne L Barber, PhD, Michael F Moran, PhD, Mark D Minden, MDPhD, Malik Slassi, PhD, Aaron D Schimmer, MDPhD
Journal: Blood
Blood (2014) 124 (21): 2226.
https://doi.org/10.1182/blood.V124.21.2226.2226
Published: 2014
Journal Articles

AML Cells Have Altered Mitochondrial Biogenesis and Low Spare Reserve Capacity in Their Respiratory Chain That Renders Them Susceptible to Oxidative Metabolic Stress.

Shrivani Sriskanthadevan, PhD, Timothy E Chung, Marko Skrtic, PhD, Bozhena Jhas, BSc, Rose Hurren, BSc, Marcela Gronda, MSc, Xiao Ming Wang, Yulia Jitkova, PhD, Mahadeo A. Sukhai, PhD, Feng-Hsu Lin, PhD, Neil Maclean, BSc, Rob C. Laister, PhD, Peter Mullen, PhD, Stephanie Xie, Linda Penn, PhD, Ian M. Rogers, PhD, John E. Dick, PhD $, Mark D. Minden, MD, PhD, Aaron D Schimmer, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2581.
https://doi.org/10.1182/blood.V120.21.2581.2581
Published: 2012