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Journal Articles

Phase II Trial of Axicabagene Ciloleucel and Glofitamab As Second-Line Therapy for Patients with Relapsed or Refractory Large B-Cell Lymphoma

Kunhwa Kim, Dai Chihara, Luis E. Fayad, Sattva S. Neelapu, Sairah Ahmed, Frederick Hagemeister, Chijioke Nze, Swaminathan P Iyer, Preetesh Jain, Michael Wang, Paolo Strati, Fateeha Furqan, Ayushi Chauhan, Michael R. Green, Christopher R. Flowers, Jason R. Westin
Journal: Blood
Blood (2024) 144 (Supplement 1): 4511.1.
https://doi.org/10.1182/blood-2024-205196
Published: 2024
Journal Articles

Atezolizumab Combined with Venetoclax and Obinutuzumab for Frontline CLL

Patrick K. Reville, Sogand Sajedi, Alessandra Ferrajoli, Jan A. Burger, Michael J. Keating, Naveen Garg, Qing Deng, Michael R. Green, Hussein A. Abbas, William G. Wierda, Nitin Jain
Journal: Blood
Blood (2024) 144 (Supplement 1): 1014.
https://doi.org/10.1182/blood-2024-206306
Published: 2024
Journal Articles

Mutagenic DNA Lesions in Normal Hematopoietic Stem Cells Persist for Years Causing Distinct Patterns of Mutation

Michael Spencer Chapman, Emily Mitchell, Kenichi Yoshida, Nicholas Williams, Margarete A. Fabre, Anna Maria Ranzoni, Philip S. Robinson, Lori Kregar, C. Matthias Wilk, Steffen Boettcher, Krishnaa Mahbubani, Kourosh Saeb-Parsy, Stanley Ng, George S Vassiliou, Kate Gowers, Sam Janes, Matt Hoare, Anthony R Green, Ana Cvejic, Markus G. Manz, Elisa Laurenti, Inigo Martincorena, Michael Stratton, Jyoti Nangalia, Tim H.H. Coorens, Peter Campbell
Journal: Blood
Blood (2024) 144 (Supplement 1): 2673.
https://doi.org/10.1182/blood-2024-208773
Published: 2024
Journal Articles

Comprehensive Characterization and Validation of the Tumor Microenvironment in Patients with Relapsed/Refractory Large B-Cell Lymphoma Identifies Subgroups with Greatest Benefit from CD19 CAR T-Cell Therapy

Xubin Li, Kartik Singhal, Qing Deng, Dai Chihara, David A Russler-Germain, Usama Hussein, Jennifer Ann Foltz, Jared Henderson, Ashley Wilson, Evelyn Schmidt, Imran A. Nizamuddin, Tommy Dinh, Ryan Sun, Akhil Kesaraju, Laura K. Hilton, David W. Scott, Francisco Vega, Christopher R. Flowers, Obi Griffith, Todd A Fehniger, Malachi Griffith, Michael R. Green
Journal: Blood
Blood (2024) 144 (Supplement 1): 643.
https://doi.org/10.1182/blood-2024-204166
Published: 2024
Journal Articles

Adaptation to ex vivo culture reduces human hematopoietic stem cell activity independently of the cell cycle

Carys S. Johnson, Matthew Williams, Kendig Sham, Serena Belluschi, Wenjuan Ma, Xiaonan Wang, Winnie W. Y. Lau, Kerstin B. Kaufmann, Gabriela Krivdova, Emily F. Calderbank, Nicole Mende, Jessica McLeod, Giovanna Mantica, Juan Li, Charlotte Grey-Wilson, Michael Drakopoulos, Shaaezmeen Basheer, Shubhankar Sinha, Evangelia Diamanti, Christina Basford, Nicola K. Wilson, Steven J. Howe, John E. Dick, Berthold Göttgens, Anthony R. Green, Natalie Francis, Elisa Laurenti
Journal: Blood
Blood (2024) 144 (7): 729–741.
https://doi.org/10.1182/blood.2023021426
Published: 2024
Includes: Supplemental data
Journal Articles

Smart Stop: Lenalidomide, Tafasitamab, Rituximab, and Acalabrutinib Alone and with Combination Chemotherapy for the Treatment of Newly Diagnosed Diffuse Large B-Cell Lymphoma

Jason Westin, Raphael E Steiner, Dai Chihara, Sairah Ahmed, Preetesh Jain, Luis Malpica, Swami P. Iyer, Luis Fayad, Ranjit Nair, Loretta J. Nastoupil, Sattva S. Neelapu, Jared Henderson, Maria Alma Rodriguez, F. B. Hagemeister, Francisco Vega, Brittani Pulsifer, Jisha Tom, Isak Durmic, Gita Masand, Lei Feng, Michael R. Green, Christopher R. Flowers, Paolo Strati
Journal: Blood
Blood (2023) 142 (Supplement 1): 856.
https://doi.org/10.1182/blood-2023-180381
Published: 2023
Journal Articles

Polygenic Germline Risk of Common Haematological Traits Drives Clonal Selection on JAK2 V617F and Development of Myeloproliferative Neoplasms

Jyoti Nangalia, Jing Guo, Klaudia Walter, Pedro Quiros, Muxin Gu, E Joanna Baxter, John Danesh, Emanuele Di Angelantonio, David Roberts, Paola Guglielmelli, Claire N Harrison, Anna L Godfrey, Anthony R Green, George Vassiliou, Dragana Vuckovic, Nicole Soranzo
Journal: Blood
Blood (2023) 142 (Supplement 1): 863.
https://doi.org/10.1182/blood-2023-189551
Published: 2023
Journal Articles

Initial Clinical Results and Immune Correlates of a Phase 2 Study of Daratumumab, Bortezomib, Dexamethasone Followed By a Proteasome Inhibitor in -Class Transition ( i CT) to Daratumumab, Ixazomib, Dexamethasone in Relapsed Refractory Multiple Myeloma

Hans C. Lee, June Li, Heather Lin, Astrid D. Murga, Gabriela M Rodriguez, Mostafa E. Mohamed, Jared Henderson, Sarah Rodriguez, Melody R. Becnel, Donna M. Weber, Swami P. Iyer, Gregory P. Kaufman, Sheeba K. Thomas, Elisabet E. Manasanch, Krina K. Patel, Stephen J. Noga, Michael R. Green, Robert Z. Orlowski, Cara L Haymaker
Journal: Blood
Blood (2023) 142 (Supplement 1): 4760.
https://doi.org/10.1182/blood-2023-188201
Published: 2023
Journal Articles

SWI/SNF Chromatin Remodeling Complex Orchestrates Sequential Binding of Key Transcription Factors in B Cells and Restricts Aggressive Lymphoma

Darko Barisic, Christopher Chin, Cem Meydan, Matthew Teater, Ioanna Tsialta, Coraline Mlynarczyk, Amy Chadburn, Min Xia, Christian Steidl, David W. Scott, Andrew P. Weng, Christopher Mason, Michael R. Green, Ari M Melnick
Journal: Blood
Blood (2023) 142 (Supplement 1): 718.
https://doi.org/10.1182/blood-2023-190494
Published: 2023
Journal Articles

IFNγ Signaling in Acute Myeloid Leukemia Mediates Immunomodulation and Reveals Therapeutic Strategies

Bofei Wang, Patrick K Reville, Fatima Z Jelloul, Poonam N Desai, Pamella Borges, Christopher Ly, Ivo Veletic, Enes Dasdemir, Jared K. Burks, Guilin Tang, Shengnan Guo, Nicole Vaugh, Natalia Baran, Qing Deng, Jairo Matthews, Preethi Gunaratne, Dinler A Antunes, Suhendan Ekmekcioglu, Koji Sasaki, Miriam B. Garcia, Branko Cuglievan, Dapeng Hao, Naval Daver, Michael R. Green, Marina Y. Konopleva, Andy Futreal, Sean M. Post, Hussein A Abbas
Journal: Blood
Blood (2023) 142 (Supplement 1): 2796.
https://doi.org/10.1182/blood-2023-175010
Published: 2023
Journal Articles

Outcomes in Patients with Relapsed Refractory T-Cell/Histiocyte-Rich Large B-Cell Lymphoma Treated with CAR-T Cell Therapies or Salvage Chemotherapy - a Single-Institution Experience

Ranjit Nair, Iyanuoluwa Ogundipe, Jillian Gunther, L. Jeffrey Medeiros, Preetesh Jain, Loretta J. Nastoupil, Chelsea Camille Pinnix, Luis Malpica, Sairah Ahmed, Roberto Miranda, Luis Fayad, Raphael E Steiner, Frederick Hagemeister, Hun Ju Lee, Maria Alma Rodriguez, Paolo Strati, Dai Chihara, Michael Wang, Yago Nieto, Jeremy Ramdial, Ajlan Al Zaki, Chijioke Nze, Michael R. Green, Bouthaina S. Dabaja, Jie Xu, Beenu Thakral, Sattva S. Neelapu, Francisco Vega, Christopher R. Flowers, Penny Fang, Jason Westin, Lei Feng, Swami P. Iyer
Journal: Blood
Blood (2023) 142 (Supplement 1): 6327.
https://doi.org/10.1182/blood-2023-191096
Published: 2023
Journal Articles

Iron homeostasis governs erythroid phenotype in polycythemia vera

Cavan Bennett, Victoria E. Jackson, Anne Pettikiriarachchi, Thomas Hayman, Ute Schaeper, Gemma Moir-Meyer, Katherine Fielding, Ricardo Ataide, Danielle Clucas, Andrew Baldi, Alexandra L. Garnham, Connie S. N. Li-Wai-Suen, Stephen J. Loughran, E. Joanna Baxter, Anthony R. Green, Warren S. Alexander, Melanie Bahlo, Kate Burbury, Ashley P. Ng, Sant-Rayn Pasricha
Journal: Blood
Blood (2023) 141 (26): 3199–3214.
https://doi.org/10.1182/blood.2022016779
Published: 2023
Includes: Supplemental data
Journal Articles

Smarca4 (Brg1) Controls Germinal Center B-Cell Development and Is a Haploinsufficient Tumor Suppressor in Lymphoma

Qing Deng, Cem Meydan, Priya Lakra, Darko Barisic, Christopher R Chin, Estela Rojas-Neira, Vida Ravanmehr, Jared Henderson, Panhong Gou, Nader Kim El-Mallawany, Carl Allen, Branko Cuglievan, Francisco Vega, Christopher E Mason, Ari Melnick, Michael R Green
Journal: Blood
Blood (2022) 140 (Supplement 1): 1690–1691.
https://doi.org/10.1182/blood-2022-166258
Published: 2022
Journal Articles

Single Cell RNA-Seq Reveals Intra-Tumoral Heterogeneity Relevant to Differentiation States and Outcomes Among Newly Diagnosed Acute Myeloid Leukemia Patients

Bofei Wang, Fatima Zahra Jelloul, Pamella Borges, Poonam Desai, Guilin Tang, Marina Konopleva, Natalia Baran, Michael R Green, Qing Deng, Naval Daver, Andy Futreal, Dapeng Hao, Hussein A Abbas
Journal: Blood
Blood (2022) 140 (Supplement 1): 6272–6273.
https://doi.org/10.1182/blood-2022-167527
Published: 2022
Journal Articles

Crebbp Kat Domain Missense Mutations Alter Its Dynamic Loading Onto Chromatin and Create a Transcription Factor Sink

Haopeng Yang, Wenchao Zhang, Vida Ravanmehr, Jared Henderson, Qing Deng, Felipe Samaniego, Fernando Rodrigues-Lima, Michael R Green
Journal: Blood
Blood (2022) 140 (Supplement 1): 8768–8769.
https://doi.org/10.1182/blood-2022-166230
Published: 2022
Journal Articles

B-Cell Receptor Signaling Modulates Cholesterol Biosynthesis in Diffuse Large B-Cell Lymphoma

Nitin Agarwal, Akanksha Aradhya, Mario L. Marques-Piubelli, Luisa M Solis Soto, Daniel Bilbao, Ralf Landgraf, Vida Ravanmehr, Jared Henderson, Michael R. Green, Eric Davis, Francisco Vega
Journal: Blood
Blood (2022) 140 (Supplement 1): 1320–1321.
https://doi.org/10.1182/blood-2022-158043
Published: 2022
Journal Articles

CD19 CAR-T Outcomes in Patients with EBV-Positive DLBCL

Ranjit Nair, Amy Ayers, Loretta J. Nastoupil, Jillian R. Gunther, Luis Fayad, Nathan H. Fowler, Roberto N. Miranda, Fredrick B. Hagemeister, Hun Ju Lee, Maria Alma Rodriguez, Raphael Steiner, Paolo Strati, Yago Nieto, Jeremy L. Ramdial, Dai Chihara, Michael L. Wang, Luis E Malpica Castillo, Neeraj Saini, Preetesh Jain, Chelsea C. Pinnix, Bouthaina S. Dabaja, Michael R Green, Christopher R. Flowers, L. Jeffrey Medeiros, Mario L. Marques-Piubelli, Francisco Vega, Mansoor Noorani, Sairah Ahmed, Jason Westin, Sattva S. Neelapu, Lei Feng, Swaminathan Padmanabhan Iyer
Journal: Blood
Blood (2022) 140 (Supplement 1): 3800–3802.
https://doi.org/10.1182/blood-2022-171120
Published: 2022
Journal Articles

Single-Cell Profiling of CD8 Landscape in Treatment Naïve and Relapsed/Refractory AML Patients Reveals Distinct Effector Cellular States Predictive of Outcomes

Poonam Desai, Bofei Wang, Fatima Zahra Jelloul, Gheath Alatrash, Natalia Baran, Qing Deng, Michael R Green, Naval Daver, Marina Konopleva, Andy Futreal, Dapeng Hao, Hussein A Abbas
Journal: Blood
Blood (2022) 140 (Supplement 1): 9144–9145.
https://doi.org/10.1182/blood-2022-167225
Published: 2022
Journal Articles

DTX1 Controls Germinal Center B-Cell Development and Lymphomagenesis

Atish Kizhakeyil, Sreejoyee Ghosh, Estela Rojas-Neira, Qing Deng, Jared Henderson, Jordan Showell, Ari Melnick, Wendy Beguelin, Francisco Vega, Loretta J. Nastoupil, Michael R Green
Journal: Blood
Blood (2022) 140 (Supplement 1): 1700–1701.
https://doi.org/10.1182/blood-2022-167086
Published: 2022
Journal Articles

Targetable Cellular Etiology of Prolonged Cytopenia Following CD19 CAR T-Cell Therapy

Xubin Li, Qing Deng, Jared Henderson, Grace Watson, Laurel Deaton, Taylor Cain, Luis Fayad, Swaminathan Padmanabhan Iyer, Fredrick B. Hagemeister, Loretta J. Nastoupil, Nathan H. Fowler, Jason Westin, Raphael Steiner, Ranjit Nair, Sairah Ahmed, Gheath Alatrash, Sattva S. Neelapu, Paolo Strati, Michael R Green
Journal: Blood
Blood (2022) 140 (Supplement 1): 4502–4503.
https://doi.org/10.1182/blood-2022-166308
Published: 2022