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Journal Articles

Protein Degrader WH25244 Eliminates Venetoclax Resistance Factors: Mutant or Hyperphosphorylated BCL2, and BCL-XL

Daisy Y. Diaz Rohena, Andrew D. Mitchell, Jing Wang, Stephanie Chamberlain, Chaomei Liu, John R. Sanchez, II, Charmelle D. Williams, Trisha K. Wathan, Bailey Slawin, Kevin Bowman, Yaxia Yuan, Peiyi Zhang, Wanyi Hu, Guangrong Zheng, William G. Wierda, Nitin Jain, Matthew S. Davids, Daohong Zhou, Jennifer A. Woyach, Deepa Sampath
Journal: Blood
Blood (2024) 144 (Supplement 1): 2786.
https://doi.org/10.1182/blood-2024-208159
Published: 2024
Journal Articles

Novel Drug to Target HK2 Overcomes Therapeutic Resistance in Preclinical B-Cell Lymphoma Models

Juan Gu, Cory Mavis, Jessica C Wang, Kevin Bowman, Taylor K Mandeville, Ahmet E Tatar, Zepnep Benekli, Matthew J Cortese, Francisco J. Hernandez-Ilizaliturri
Journal: Blood
Blood (2023) 142 (Supplement 1): 5793.
https://doi.org/10.1182/blood-2023-185189
Published: 2023
Journal Articles

Venetoclax Pre-Treatment of CLL/SLL Patients Enhances Autologous CAR T-Cells Efficacy

Matthew J Cortese, Cory Mavis, Taylor K Mandeville, Juan Gu, Kevin Bowman, Francisco J. Hernandez-Ilizaliturri
Journal: Blood
Blood (2023) 142 (Supplement 1): 6518.
https://doi.org/10.1182/blood-2023-189733
Published: 2023
Journal Articles

Compatibility of Venetoclax and OPN51107 in Treatment of Mantle Cell Lymphoma

Kevin Bowman, Cory Mavis, Juan Gu, Taylor K Mandeville, Jessica C Wang, Matthew J Cortese, Francisco J. Hernandez-Ilizaliturri
Journal: Blood
Blood (2023) 142 (Supplement 1): 6102.
https://doi.org/10.1182/blood-2023-189739
Published: 2023
Journal Articles

Mitochondrial Reprogramming By Bcl-2 Inhibitor Venetoclax Enhances αCD19 CAR-T Cell Fitness and Anti-Tumor Efficacy

Taylor K Mandeville, Cory Mavis, Juan Gu, Kevin Bowman, Scott Olejniczak, Prasenjit Dey, Gyorgy Paragh, Matthew J Cortese, Francisco J. Hernandez-Ilizaliturri
Journal: Blood
Blood (2023) 142 (Supplement 1): 6845.
https://doi.org/10.1182/blood-2023-191051
Published: 2023
Journal Articles

Enhanced Anti-Tumor Activity with Exposure to BCL-2 and BRD4 Inhibitors in Mantle Cell Lymphoma

Kevin Bowman, Cory Mavis, Taylor K Mandeville, Noah Lemoine, Juan Gu, Francisco Hernandez-Ilizaliturri
Journal: Blood
Blood (2022) 140 (Supplement 1): 8850.
https://doi.org/10.1182/blood-2022-169438
Published: 2022
Journal Articles

Enhancing α-CD19 CAR T Antitumor Efficacy Using the BH3 Mimetic, Venetoclax

Taylor Mandeville, Cory Mavis, Juan Gu, Noah Lemoine, Kevin Bowman, Scott Olejniczak, Prasenjit Dey, Gyorgy Paragh, Francisco Hernandez-Ilizaliturri
Journal: Blood
Blood (2022) 140 (Supplement 1): 7398–7399.
https://doi.org/10.1182/blood-2022-170436
Published: 2022
Journal Articles

Effect of Mcl-1 Inhibitor, AMG-176, on T Cell Quality and Function

Noah Lemoine, Taylor K Mandeville, Cory Mavis, Kevin Bowman, Juan J. Gu, Francisco Hernandez-Ilizaliturri
Journal: Blood
Blood (2022) 140 (Supplement 1): 12706–12707.
https://doi.org/10.1182/blood-2022-170122
Published: 2022
Journal Articles

Characterization of INCB00928, a Potent and Selective ALK2 Inhibitor for the Treatment of Anemia

Yaoyu Chen, Matthew C. Stubbs, PhD, Michelle Pusey, Xiaoming Wen, Robert J. Collins, Kanishk Kapilashrami, Mark Rupar, Pramod Thekkat, Luping Lin, PhD, Kevin Bowman, Yan-ou Yang, Sharon Diamond, Swamy Yeleswaram, PhD, Sunkyu Kim, Holly K. Koblish, PhD, Yingnan Chen, Susan Wee, PhD BS
Journal: Blood
Blood (2020) 136 (Supplement 1): 52.
https://doi.org/10.1182/blood-2020-136138
Published: 2020
Journal Articles

LSD1 Inhibition Induces Fetal Hemoglobin Expression and Provides a Novel Therapeutic Approach to Sickle Cell Disease

Sang Hyun Lee, PhD, Maxim Soloviev, MDPhD, Yan Zhang, PhD, Valerie Roman, Gengjie Yang, Kevin Bowman, Krista Burke, Alexander Margulis, Sybil O'Connor, Yan-ou Yang, PhD, Liangxing Wu, PhD, Richard Wynn, PhD, Timothy Burn, PhD, Dana Shuey, PhD, Sharon Diamond, PhD, Wenqing Yao, PhD, Gregory Hollis, PhD, Swamy Yeleswaram, PhD, Alan Roberts, PhD, Reid Huber, PhD, Peggy Scherle, PhD, Bruce Ruggeri, PhD
Journal: Blood
Blood (2016) 128 (22): 2472.
https://doi.org/10.1182/blood.V128.22.2472.2472
Published: 2016