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Journal Articles

Characterization of INCB00928, a Potent and Selective ALK2 Inhibitor for the Treatment of Anemia

Yaoyu Chen, Matthew C. Stubbs, PhD, Michelle Pusey, Xiaoming Wen, Robert J. Collins, Kanishk Kapilashrami, Mark Rupar, Pramod Thekkat, Luping Lin, PhD, Kevin Bowman, Yan-ou Yang, Sharon Diamond, Swamy Yeleswaram, PhD, Sunkyu Kim, Holly K. Koblish, PhD, Yingnan Chen, Susan Wee, PhD BS
Journal: Blood
Blood (2020) 136 (Supplement 1): 52.
https://doi.org/10.1182/blood-2020-136138
Published: 2020
Journal Articles

PFKFB3 Is a Crucial Target in the Treatment of Tyrosine Kinase Inhibitor Resistant Chronic Myelogenous Leukemia

Yu Zhu, Jianyong Li, Chun Qiao, Yi Shan, MD, Sixuan Qian, Yaoyu Chen, Ming Hong, Huihui Zhao, Huapeng LI, Xuejun Zhu, Yang Zhongfa
Journal: Blood
Blood (2016) 128 (22): 3936.
https://doi.org/10.1182/blood.V128.22.3936.3936
Published: 2016
Journal Articles

TP53-Induced Glycolysis and Apoptosis Regulator Protects from Spontaneous Apoptosis and Predicts Poor Prognosis in Chronic Lymphocytic Leukemia

Ming Hong, Yi Xia, Yu Zhu, MD, Huihui Zhao, Yue Xie, Lei Fan, MD, PhD, Li Wang, Kourong Miao, MD, Wei Wu, Huayuan Zhu, MD, Yaoyu Chen, Wei Xu, Sixuan Qian, Jianyong Li
Journal: Blood
Blood (2016) 128 (22): 5101.
https://doi.org/10.1182/blood.V128.22.5101.5101
Published: 2016
Journal Articles

Genetic and Pharmacologic Targeting Of Alox5 Attenuates JAK2V617F Induced PV In Mice

Yaoyu Chen, MD, PhD, Yi Shan, Zhiru Guo, PhD, Aibin Liang, MD, PhD, Shaoguang Li, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 112.
https://doi.org/10.1182/blood.V122.21.112.112
Published: 2013
Journal Articles

Nfkb1 Plays a Tumor-Suppressing Role in BCR-ABL-Induced Leukemias

Con Sullivan, Yaoyu Chen, Zhiru Guo, Yi Shan, Cong Peng, Haojian Zhang, Jason Bubier, Thomas Sproule, Derry Roopenian, Shaoguang Li, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 1666.
https://doi.org/10.1182/blood.V120.21.1666.1666
Published: 2012
Journal Articles

PRKD2 Serine-Threonine Kinase, an Essential Effector of Gabp Transcription Factor, Is Required for Development of Chronic Myelogenous Leukemia

Zhong-Fa Yang, PhD, Haojian Zhang, Leyuan Ma, Cong Peng, PhD, Yaoyu Chen, Michael Green, Shaoguang Li, MD, PhD, Alan G. Rosmarin, MD
Journal: Blood
Blood (2012) 120 (21): 1672.
https://doi.org/10.1182/blood.V120.21.1672.1672
Published: 2012
Journal Articles

Without GABP Transcription Factor, BCR-ABL Cannot Transform HSCs to Leukemic Stem Cells Nor Induce Chronic Myelogenous Leukemia in Mice

Zhongfa Yang, PhD, Cong Peng, Yaoyu Chen, Junling Wang, Xuejun Zhu, Karen Drumea, MD, Shaoguang Li, MD, PhD, Alan G. Rosmarin, MD
Journal: Blood
Blood (2011) 118 (21): 965.
https://doi.org/10.1182/blood.V118.21.965.965
Published: 2011
Journal Articles

A tumor suppressor function of the Msr1 gene in leukemia stem cells of chronic myeloid leukemia

Yaoyu Chen, Con Sullivan, Cong Peng, Yi Shan, Yiguo Hu, Dongguang Li, Shaoguang Li
Journal: Blood
Blood (2011) 118 (2): 390–400.
https://doi.org/10.1182/blood-2010-11-316760
Published: 2011
Includes: Supplemental data
Journal Articles

Loss of P-Selectin Promotes the Function of Aged Hematopoietic and Leukemic Stem Cells.

Yaoyu Chen, Sullivan Con, Yiguo Hu, Linghong Kong, Cong Peng, Shaoguang Li, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 1577.
https://doi.org/10.1182/blood.V116.21.1577.1577
Published: 2010
Journal Articles

PTEN is a tumor suppressor in CML stem cells and BCR-ABL–induced leukemias in mice

Cong Peng, Yaoyu Chen, Zhongfa Yang, Haojian Zhang, Lori Osterby, Alan G. Rosmarin, Shaoguang Li
Journal: Blood
Blood (2010) 115 (3): 626–635.
https://doi.org/10.1182/blood-2009-06-228130
Published: 2010
Includes: Supplemental data
Journal Articles

The Tumor Suppressor Role of the Msr1 Gene in Cancer Stem Cells of Chronic Myeloid Leukemia.

Yaoyu Chen, Con Sullivan, Shaoguang Li
Journal: Blood
Blood (2009) 114 (22): 188.
https://doi.org/10.1182/blood.V114.22.188.188
Published: 2009
Journal Articles

Beta-catenin Is Essential for Survival of Leukemia Stem Cells Insensitive to Kinase Inhibition in Mice with BCR-ABL Induced Chronic Myeloid Leukemia.

Shaoguang Li, Yiguo Hu, Yaoyu Chen, Lori Douglas
Journal: Blood
Blood (2008) 112 (11): 1080.
https://doi.org/10.1182/blood.V112.11.1080.1080
Published: 2008
Journal Articles

Inhibitory Effects of Homoharringtonine on Leukemic Stem Cells and BCR-ABL Induced Chronic Myeloid Leukemia and Acute Lymphoblastic Leukemia in Mice.

Yaoyu Chen, MD, Yiguo Hu, MD., PhD, Shawnya Michaels, PhD, Dennis Brown, PhD, Shaoguang Li, MD, PhD
Journal: Blood
Blood (2007) 110 (11): 2912.
https://doi.org/10.1182/blood.V110.11.2912.2912
Published: 2007