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Journal Articles

ALK2 and JAK2 Inhibition for Improved Treatment of Anemia in Myelofibrosis Patients: Preclinical Profile of an ALK2 Inhibitor Zilurgisertib in Combination with Ruxolitinib

Matthew C. Stubbs, Michelle Pusey, Xiaoming Wen, Katherine Drake, Nina Zolotarjova, Amanda Smith, Maryanne Covington, Guofeng Zhang, Ricardo Macarrón, Sunkyu Kim
Journal: Blood
Blood (2023) 142 (Supplement 1): 1789.
https://doi.org/10.1182/blood-2023-181055
Published: 2023
Journal Articles

Preclinical Evaluation of INCB160058 - a Novel and Potentially Disease-Modifying Therapy for JAK2V617F Mutant Myeloproliferative Neoplasms

Matthew C. Stubbs, Hamza Celik, Yanran Ai, Xin He, Hong Chang, Angela Lei, Mark Rupar, Brittney Wass, Melody Diamond, Xiaoming Wen, Jun Li, Nina Zolotarjova, Alex Margulis, Gaurang Trivedi, Angelo B.A. Laranjeira, Cooper A. Taylor, Jennifer Rocha, Christoph Pollmann, Jacob Piehler, Bianca L. Ferreira, Ian Hitchcock, Ricardo Macarrón, Eddy W. Yue, Sunkyu Kim
Journal: Blood
Blood (2023) 142 (Supplement 1): 860.
https://doi.org/10.1182/blood-2023-179369
Published: 2023
Journal Articles

Comparison of the Enzymatic and Cellular Profiles of Clinical JAK2 Inhibitors for the Treatment of Myelofibrosis

Hamza Celik, Maryanne Covington, Katherine Drake, Kamna Katiyar, Alex Margulis, Amanda Smith, Gaurang Trivedi, Brittney Wass, Guofeng Zhang, Nina Zolotarjova, Sunkyu Kim, Ricardo Macarrón
Journal: Blood
Blood (2023) 142 (Supplement 1): 4532.
https://doi.org/10.1182/blood-2023-174917
Published: 2023
Journal Articles

Characterization of INCB00928, a Potent and Selective ALK2 Inhibitor for the Treatment of Anemia

Yaoyu Chen, Matthew C. Stubbs, PhD, Michelle Pusey, Xiaoming Wen, Robert J. Collins, Kanishk Kapilashrami, Mark Rupar, Pramod Thekkat, Luping Lin, PhD, Kevin Bowman, Yan-ou Yang, Sharon Diamond, Swamy Yeleswaram, PhD, Sunkyu Kim, Holly K. Koblish, PhD, Yingnan Chen, Susan Wee, PhD BS
Journal: Blood
Blood (2020) 136 (Supplement 1): 52.
https://doi.org/10.1182/blood-2020-136138
Published: 2020
Journal Articles

Synergistic Drug Combinations with a CDK4/6 Inhibitor in T-Cell Acute Lymphoblastic Leukemia

Yana Pikman, MD, Andrew Furman, BA, Emily S. Lee, Andrew E. Place, MDPhD, Gabriela Alexe, PhD, Rebecca Modiste, RT(N), LAT, Prafulla Gokhale, PhD, Sunkyu Kim, PhD, Lewis B. Silverman, MD, Kimberly Stegmaier, MD
Journal: Blood
Blood (2015) 126 (23): 2488.
https://doi.org/10.1182/blood.V126.23.2488.2488
Published: 2015